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The map label for this gene is ggt [H]

Identifier: 50084136

GI number: 50084136

Start: 911211

End: 913172

Strand: Direct

Name: ggt [H]

Synonym: ACIAD0929

Alternate gene names: 50084136

Gene position: 911211-913172 (Clockwise)

Preceding gene: 50084135

Following gene: 50084139

Centisome position: 25.32

GC content: 45.26

Gene sequence:

>1962_bases
ATGCAAAAAAAATATTTCCTCATTCTGGGAGGTTTTTTAAGTTTAGGATTGTTACAGGGGTGTAATGATTCAAATGATCA
GGAACAAACATCTACAATCGTAGATACCAACCCGAATAGCTGTAATCAGCTGACTAGTGATGGCTCAACTGTCGTGGTAG
GCAGTGGGCAAGTCGGCGATCCTTCGGCACCCGAACCTGCCTCTGCATATCGTTTGGGTTTAAAAGCAAAAACATCAAAT
CAATATATGGTCGTTGCCAATACACCACTGGCGACTAAAGCAGGCTGTGACATCTTAAAAGCAGGTGGTTCGGCTGTAGA
TGCAGCAATTGCTGTACAAGCCGTACTGGGTTTGGTCGAACCACAATCGAGTACCATTGCAGGTAGTGCATTTATGATGT
ACTACGATGCCCAAACTCAAAAAGTCACAGCCTATGATGGCCGAGAAACTGCCCCAGCAGCAGCCAATGAATATTATCTG
GTTCGTCAGAATCTAGAGGATCCAAACTCACTCGCACCCGTGCCAAGTGCAAGACGTAGTGGTCGTTCGATTGGGGTGCC
TGGTGTGATGCGTATGCTGGAAATGGCGCATAACGAACATGGTAAATTAAGATGGAATCAATTATTTGATAACTCCGTAC
AATTAGCCGAAGGTGGTTTTAAAGTACCAGGACGACTGGCAGCCGCTATTCAAAGTAATGCAGCTTCATTGGCTCTGGAT
GCAAATGCAGTAAAAACTTACTTTCATGCAGATGGTTCTCCTTATCAGGTGGGAGAAACCATGACCAATCAGGACTATGC
ACGCACCATTCGTACGATTGCGGCGAATGGTGCTCAAGCAATGTATAGTGGAACAATTGCACAGGCAATCATTGCTAAAG
CTCAACAAGATAAAGGTGATGATGCCGCCAATACGCCCATTACTCCAAGTCTGATGACACTGAATGATTTAGCCAATTAT
CAAGCCAAGAAGCGTGATGCCATCTGTTTTACTTATCGTAGCCAGTATCATGTATGTACCATGCCACCGCCATCATCAGG
AGGGATTGCTGTGGCTCAGACGCTGGGAATTTTAGAGAATTTTGATCTTGCATCATATGGCCCGACACAGCCTGAAACCG
AGGGTGGTGTGCCTACGGTGATGGGTGTGCATTTAGTTTCCGAGGCTGAGCGTCTGGCGTATGCCGATCGTGATAAATAT
GTCGCAGATACCGATTTTGTGCCGCTTCCCGCTCAAGGTGTCAGCAGCATGCTCAATAAAAACTATTTGAAGCAACGTGC
GGGTTTGATTAATCCAGATCAAAGCATGAAAGTCGCAACTGCTGGAGACTTTAGTGTCAATGCGGGTATTGATAATACTG
TAGAGCATGGAACAACTCAGTTTACGATTGCAGATGCTTATGGCAATGTTGTGTCTATGACATCTACGGTTGAGTCGAGT
ATGGGTTCATTCCATATGGTTGATGGATTCTTGCTGACCAATCAATTGACAGATTTTAGTGCACAGCCAGTAGATAGCAC
AGGTAATTTGGTTGCAAACCGTGTTCAAGCCAATAAACGGCCAAGAAGTACCATGGCACCGACGTTGGTCTTTAAAGGGA
CTGCACCAGGTGATTTCTATATGGCAACGGGTTCACCAGGCGGCGGTACGATTATCCAGTATGTGGTCAAAACACTGGTA
GGCGCACTAGACTGGAATTTAGATGCACAGCAAGCGACTTCACTTGTGAATTTTGGTGCGACCAATAGCGCAAATACCAA
TGTAGATAGTTCAAATACTTCACTTGATCTAACTGCACTCATCGATGGCTTAAAAGCTAAAGGTCATGGCATTAATTCTT
CGGCACAAAGTAGTGGGGTTGCTACCATTATGCGCATTGCCATACAAAATCAGCAGATTAAGTATGTGGGTGGCGTCGAC
CCTCGACGTGAAGGTATTGTACTGGGTAATGGTGCTTTATAG

Upstream 100 bases:

>100_bases
TATTAAGCATTTGATATAAAAGGTAATTTATTTTTTCTAAATATTGGCTCCATAATTGCTTGGAAGGAACACTTAATAAT
GAAATATAAATGGAGATGCA

Downstream 100 bases:

>100_bases
TTTCAGGCATTTAATTTAGATCAATAAAAAAGCTGCAAGTTATTGCAGCTTTTTTATTTATATCAAATTGGACTTCGCTC
TTTTGAGTGCCTGACTCCAT

Product: gamma-glutamyltranspeptidase precursor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 653; Mature: 653

Protein sequence:

>653_residues
MQKKYFLILGGFLSLGLLQGCNDSNDQEQTSTIVDTNPNSCNQLTSDGSTVVVGSGQVGDPSAPEPASAYRLGLKAKTSN
QYMVVANTPLATKAGCDILKAGGSAVDAAIAVQAVLGLVEPQSSTIAGSAFMMYYDAQTQKVTAYDGRETAPAAANEYYL
VRQNLEDPNSLAPVPSARRSGRSIGVPGVMRMLEMAHNEHGKLRWNQLFDNSVQLAEGGFKVPGRLAAAIQSNAASLALD
ANAVKTYFHADGSPYQVGETMTNQDYARTIRTIAANGAQAMYSGTIAQAIIAKAQQDKGDDAANTPITPSLMTLNDLANY
QAKKRDAICFTYRSQYHVCTMPPPSSGGIAVAQTLGILENFDLASYGPTQPETEGGVPTVMGVHLVSEAERLAYADRDKY
VADTDFVPLPAQGVSSMLNKNYLKQRAGLINPDQSMKVATAGDFSVNAGIDNTVEHGTTQFTIADAYGNVVSMTSTVESS
MGSFHMVDGFLLTNQLTDFSAQPVDSTGNLVANRVQANKRPRSTMAPTLVFKGTAPGDFYMATGSPGGGTIIQYVVKTLV
GALDWNLDAQQATSLVNFGATNSANTNVDSSNTSLDLTALIDGLKAKGHGINSSAQSSGVATIMRIAIQNQQIKYVGGVD
PRREGIVLGNGAL

Sequences:

>Translated_653_residues
MQKKYFLILGGFLSLGLLQGCNDSNDQEQTSTIVDTNPNSCNQLTSDGSTVVVGSGQVGDPSAPEPASAYRLGLKAKTSN
QYMVVANTPLATKAGCDILKAGGSAVDAAIAVQAVLGLVEPQSSTIAGSAFMMYYDAQTQKVTAYDGRETAPAAANEYYL
VRQNLEDPNSLAPVPSARRSGRSIGVPGVMRMLEMAHNEHGKLRWNQLFDNSVQLAEGGFKVPGRLAAAIQSNAASLALD
ANAVKTYFHADGSPYQVGETMTNQDYARTIRTIAANGAQAMYSGTIAQAIIAKAQQDKGDDAANTPITPSLMTLNDLANY
QAKKRDAICFTYRSQYHVCTMPPPSSGGIAVAQTLGILENFDLASYGPTQPETEGGVPTVMGVHLVSEAERLAYADRDKY
VADTDFVPLPAQGVSSMLNKNYLKQRAGLINPDQSMKVATAGDFSVNAGIDNTVEHGTTQFTIADAYGNVVSMTSTVESS
MGSFHMVDGFLLTNQLTDFSAQPVDSTGNLVANRVQANKRPRSTMAPTLVFKGTAPGDFYMATGSPGGGTIIQYVVKTLV
GALDWNLDAQQATSLVNFGATNSANTNVDSSNTSLDLTALIDGLKAKGHGINSSAQSSGVATIMRIAIQNQQIKYVGGVD
PRREGIVLGNGAL
>Mature_653_residues
MQKKYFLILGGFLSLGLLQGCNDSNDQEQTSTIVDTNPNSCNQLTSDGSTVVVGSGQVGDPSAPEPASAYRLGLKAKTSN
QYMVVANTPLATKAGCDILKAGGSAVDAAIAVQAVLGLVEPQSSTIAGSAFMMYYDAQTQKVTAYDGRETAPAAANEYYL
VRQNLEDPNSLAPVPSARRSGRSIGVPGVMRMLEMAHNEHGKLRWNQLFDNSVQLAEGGFKVPGRLAAAIQSNAASLALD
ANAVKTYFHADGSPYQVGETMTNQDYARTIRTIAANGAQAMYSGTIAQAIIAKAQQDKGDDAANTPITPSLMTLNDLANY
QAKKRDAICFTYRSQYHVCTMPPPSSGGIAVAQTLGILENFDLASYGPTQPETEGGVPTVMGVHLVSEAERLAYADRDKY
VADTDFVPLPAQGVSSMLNKNYLKQRAGLINPDQSMKVATAGDFSVNAGIDNTVEHGTTQFTIADAYGNVVSMTSTVESS
MGSFHMVDGFLLTNQLTDFSAQPVDSTGNLVANRVQANKRPRSTMAPTLVFKGTAPGDFYMATGSPGGGTIIQYVVKTLV
GALDWNLDAQQATSLVNFGATNSANTNVDSSNTSLDLTALIDGLKAKGHGINSSAQSSGVATIMRIAIQNQQIKYVGGVD
PRREGIVLGNGAL

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=496, Percent_Identity=29.0322580645161, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI73915090, Length=496, Percent_Identity=29.0322580645161, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI73915096, Length=496, Percent_Identity=29.0322580645161, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI73915094, Length=496, Percent_Identity=29.0322580645161, Blast_Score=164, Evalue=2e-40,
Organism=Homo sapiens, GI109148539, Length=541, Percent_Identity=26.4325323475046, Blast_Score=143, Evalue=5e-34,
Organism=Homo sapiens, GI113429324, Length=552, Percent_Identity=26.4492753623188, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI113429326, Length=558, Percent_Identity=26.1648745519713, Blast_Score=132, Evalue=8e-31,
Organism=Homo sapiens, GI153266901, Length=508, Percent_Identity=23.8188976377953, Blast_Score=119, Evalue=1e-26,
Organism=Homo sapiens, GI153266885, Length=507, Percent_Identity=24.0631163708087, Blast_Score=118, Evalue=2e-26,
Organism=Homo sapiens, GI153266907, Length=507, Percent_Identity=22.2879684418146, Blast_Score=98, Evalue=2e-20,
Organism=Escherichia coli, GI1789856, Length=512, Percent_Identity=34.765625, Blast_Score=257, Evalue=2e-69,
Organism=Caenorhabditis elegans, GI17542894, Length=511, Percent_Identity=28.9628180039139, Blast_Score=161, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI193208245, Length=545, Percent_Identity=28.6238532110092, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI193208247, Length=546, Percent_Identity=28.7545787545788, Blast_Score=160, Evalue=3e-39,
Organism=Caenorhabditis elegans, GI17506189, Length=505, Percent_Identity=27.7227722772277, Blast_Score=145, Evalue=8e-35,
Organism=Caenorhabditis elegans, GI212646519, Length=541, Percent_Identity=27.3567467652495, Blast_Score=141, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI72000294, Length=541, Percent_Identity=27.3567467652495, Blast_Score=141, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6323330, Length=531, Percent_Identity=23.728813559322, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI161077880, Length=601, Percent_Identity=27.6206322795341, Blast_Score=153, Evalue=3e-37,
Organism=Drosophila melanogaster, GI45551474, Length=601, Percent_Identity=27.6206322795341, Blast_Score=153, Evalue=4e-37,
Organism=Drosophila melanogaster, GI161077878, Length=601, Percent_Identity=27.6206322795341, Blast_Score=153, Evalue=5e-37,
Organism=Drosophila melanogaster, GI24642670, Length=601, Percent_Identity=27.6206322795341, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI24642666, Length=601, Percent_Identity=27.6206322795341, Blast_Score=152, Evalue=6e-37,
Organism=Drosophila melanogaster, GI18859893, Length=588, Percent_Identity=28.2312925170068, Blast_Score=140, Evalue=4e-33,
Organism=Drosophila melanogaster, GI161077496, Length=500, Percent_Identity=23.8, Blast_Score=115, Evalue=1e-25,
Organism=Drosophila melanogaster, GI18859741, Length=493, Percent_Identity=25.5578093306288, Blast_Score=110, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 68786; Mature: 68786

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQKKYFLILGGFLSLGLLQGCNDSNDQEQTSTIVDTNPNSCNQLTSDGSTVVVGSGQVGD
CCCEEEEEECHHHHHHHHHCCCCCCCCHHHCEEEECCCCCHHHHCCCCCEEEEECCCCCC
PSAPEPASAYRLGLKAKTSNQYMVVANTPLATKAGCDILKAGGSAVDAAIAVQAVLGLVE
CCCCCCCHHHEEEEEEECCCCEEEEECCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCC
PQSSTIAGSAFMMYYDAQTQKVTAYDGRETAPAAANEYYLVRQNLEDPNSLAPVPSARRS
CCCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHC
GRSIGVPGVMRMLEMAHNEHGKLRWNQLFDNSVQLAEGGFKVPGRLAAAIQSNAASLALD
CCCCCCHHHHHHHHHHHCCCCCEEHHHHCCCCEEECCCCCCCCHHHHHHHHCCCCEEEEE
ANAVKTYFHADGSPYQVGETMTNQDYARTIRTIAANGAQAMYSGTIAQAIIAKAQQDKGD
CHHEEEEEECCCCCEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
DAANTPITPSLMTLNDLANYQAKKRDAICFTYRSQYHVCTMPPPSSGGIAVAQTLGILEN
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHC
FDLASYGPTQPETEGGVPTVMGVHLVSEAERLAYADRDKYVADTDFVPLPAQGVSSMLNK
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHH
NYLKQRAGLINPDQSMKVATAGDFSVNAGIDNTVEHGTTQFTIADAYGNVVSMTSTVESS
HHHHHHCCCCCCCCCEEEEECCCCEEECCCCCCHHCCCEEEEEECCCCCEEEHHHHHHHH
MGSFHMVDGFLLTNQLTDFSAQPVDSTGNLVANRVQANKRPRSTMAPTLVFKGTAPGDFY
CCCEEEECCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEE
MATGSPGGGTIIQYVVKTLVGALDWNLDAQQATSLVNFGATNSANTNVDSSNTSLDLTAL
EEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHH
IDGLKAKGHGINSSAQSSGVATIMRIAIQNQQIKYVGGVDPRREGIVLGNGAL
HHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEECCCC
>Mature Secondary Structure
MQKKYFLILGGFLSLGLLQGCNDSNDQEQTSTIVDTNPNSCNQLTSDGSTVVVGSGQVGD
CCCEEEEEECHHHHHHHHHCCCCCCCCHHHCEEEECCCCCHHHHCCCCCEEEEECCCCCC
PSAPEPASAYRLGLKAKTSNQYMVVANTPLATKAGCDILKAGGSAVDAAIAVQAVLGLVE
CCCCCCCHHHEEEEEEECCCCEEEEECCCCCCCCCCHHHHCCCCHHHHHHHHHHHHHHCC
PQSSTIAGSAFMMYYDAQTQKVTAYDGRETAPAAANEYYLVRQNLEDPNSLAPVPSARRS
CCCCCCCCCEEEEEEECCCCEEEECCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCHHHC
GRSIGVPGVMRMLEMAHNEHGKLRWNQLFDNSVQLAEGGFKVPGRLAAAIQSNAASLALD
CCCCCCHHHHHHHHHHHCCCCCEEHHHHCCCCEEECCCCCCCCHHHHHHHHCCCCEEEEE
ANAVKTYFHADGSPYQVGETMTNQDYARTIRTIAANGAQAMYSGTIAQAIIAKAQQDKGD
CHHEEEEEECCCCCEECCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC
DAANTPITPSLMTLNDLANYQAKKRDAICFTYRSQYHVCTMPPPSSGGIAVAQTLGILEN
CCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCCCCHHHHHHHHHHC
FDLASYGPTQPETEGGVPTVMGVHLVSEAERLAYADRDKYVADTDFVPLPAQGVSSMLNK
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHH
NYLKQRAGLINPDQSMKVATAGDFSVNAGIDNTVEHGTTQFTIADAYGNVVSMTSTVESS
HHHHHHCCCCCCCCCEEEEECCCCEEECCCCCCHHCCCEEEEEECCCCCEEEHHHHHHHH
MGSFHMVDGFLLTNQLTDFSAQPVDSTGNLVANRVQANKRPRSTMAPTLVFKGTAPGDFY
CCCEEEECCEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCEEEEECCCCCCEE
MATGSPGGGTIIQYVVKTLVGALDWNLDAQQATSLVNFGATNSANTNVDSSNTSLDLTAL
EEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHH
IDGLKAKGHGINSSAQSSGVATIMRIAIQNQQIKYVGGVDPRREGIVLGNGAL
HHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCEEEEECCCCCCCCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA