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The map label for this gene is emrA [H]

Identifier: 50084134

GI number: 50084134

Start: 908317

End: 909453

Strand: Direct

Name: emrA [H]

Synonym: ACIAD0926

Alternate gene names: 50084134

Gene position: 908317-909453 (Clockwise)

Preceding gene: 50084132

Following gene: 50084135

Centisome position: 25.24

GC content: 44.94

Gene sequence:

>1137_bases
ATGACTGAATCTGCACAAGTGACTGCATCAGACGTAGATGATGATGCTTTAAAGGCGAAACGAAAGAAATTACTGAGTAT
TTTTGCCTTGGTTATTGTGATTGTTGCGATTTTATATGCAATCTGGTTTTTCTTCTTTAATCATACTGTCAGTACTGACA
ATGCTTATGTCGGGGCGGAAACTGCACAGATTACCTCTATGGTGACAGGGCAGGTTGCTGAAATTCGTGTACATGATACG
CAACAAGTACATAAAGGCGATATCTTGGCTCAGGTGGATCCAAGAGATGCACAGATTGCATTGAGCCAGGCACAAGCGAT
GCTGGCCAAAGCACAACGTCAGTATCGTCAGACAGAAGCCAACAGTAAATCTTTAAACTCTCAAGTCTTTGTAAGTGATG
ATGGAATTGCAAGTGCCCAGGCACAGGTAGGCAAGGCTCAAGCTGACTATAATAATGCCATTGAAGAGTTAAAACGTAGA
CAGACGCTTGAACAATCTGGCGCAATTTCTAAAGAAGAATTGAGTACGGCGCAAACAGCGGCACAAACTGCCAAAGCTGC
ACTAGATGTCGCTAAGGCAGCTGTTTCTCAGGCACAGTCAAGTCGCAAGGCAGCACAAAGTAACTTGGCAGCCAATCAGG
CCTTGATTCAGGGAGCCTCTGAAAACTCGGCACCAGATGTATTAAGCGCTGAAGCCAATGTACAACAAGCGCAGCTTGAT
CTTGAGCGTACCGTAATTCGTTCACCTGTTGATGGGGTCATTACAGGCCGTAATATTCAAGTGGGTCAGCGTGTGGCTCC
TGGTAGCGTACTCATGAAAATTGTTCCGCTTTCTGCGTTATATGTCGATGCAAACTTTAAAGAAAGTCAATTATCTAAAG
TACGTGTCGGGCAAGCAGCGACCTTAACGTCTGATTTATACGGCAGTGACGTTGAATATCACGGTAAGGTGATTGGATTC
TCGGGAGGAACAGGTTCTGCATTTGCGCTGATTCCTGCACAAAATGCAACAGGCAATTGGATTAAAGTGGTTCAGCGTTT
ACCAGTGCGTATCGCACTTGATCCGAAAGAATTGGCTGAGCATCCGTTACGTGTTGGGCTGTCTATGGATGCTAGCATCG
ATTTATCCAAGAAGTAA

Upstream 100 bases:

>100_bases
TTTAGTTTTATTTTAAGTTTCAGTTCAGGTTCAATTCCTAAACTTAAAATTAACTTAAGAAAATCGTGACAATTAGACCT
GAGCCATTTAGGAATACACA

Downstream 100 bases:

>100_bases
CCTATTATGACCGCTCAAAGTCAGGCTTCTTCGACCAAAACCCCTTTTGCTGAACTCAGTGGCGGACGATTACTGCTCGC
TGCATTTGTGATTGCACTTT

Product: multidrug resistance secretion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 378; Mature: 377

Protein sequence:

>378_residues
MTESAQVTASDVDDDALKAKRKKLLSIFALVIVIVAILYAIWFFFFNHTVSTDNAYVGAETAQITSMVTGQVAEIRVHDT
QQVHKGDILAQVDPRDAQIALSQAQAMLAKAQRQYRQTEANSKSLNSQVFVSDDGIASAQAQVGKAQADYNNAIEELKRR
QTLEQSGAISKEELSTAQTAAQTAKAALDVAKAAVSQAQSSRKAAQSNLAANQALIQGASENSAPDVLSAEANVQQAQLD
LERTVIRSPVDGVITGRNIQVGQRVAPGSVLMKIVPLSALYVDANFKESQLSKVRVGQAATLTSDLYGSDVEYHGKVIGF
SGGTGSAFALIPAQNATGNWIKVVQRLPVRIALDPKELAEHPLRVGLSMDASIDLSKK

Sequences:

>Translated_378_residues
MTESAQVTASDVDDDALKAKRKKLLSIFALVIVIVAILYAIWFFFFNHTVSTDNAYVGAETAQITSMVTGQVAEIRVHDT
QQVHKGDILAQVDPRDAQIALSQAQAMLAKAQRQYRQTEANSKSLNSQVFVSDDGIASAQAQVGKAQADYNNAIEELKRR
QTLEQSGAISKEELSTAQTAAQTAKAALDVAKAAVSQAQSSRKAAQSNLAANQALIQGASENSAPDVLSAEANVQQAQLD
LERTVIRSPVDGVITGRNIQVGQRVAPGSVLMKIVPLSALYVDANFKESQLSKVRVGQAATLTSDLYGSDVEYHGKVIGF
SGGTGSAFALIPAQNATGNWIKVVQRLPVRIALDPKELAEHPLRVGLSMDASIDLSKK
>Mature_377_residues
TESAQVTASDVDDDALKAKRKKLLSIFALVIVIVAILYAIWFFFFNHTVSTDNAYVGAETAQITSMVTGQVAEIRVHDTQ
QVHKGDILAQVDPRDAQIALSQAQAMLAKAQRQYRQTEANSKSLNSQVFVSDDGIASAQAQVGKAQADYNNAIEELKRRQ
TLEQSGAISKEELSTAQTAAQTAKAALDVAKAAVSQAQSSRKAAQSNLAANQALIQGASENSAPDVLSAEANVQQAQLDL
ERTVIRSPVDGVITGRNIQVGQRVAPGSVLMKIVPLSALYVDANFKESQLSKVRVGQAATLTSDLYGSDVEYHGKVIGFS
GGTGSAFALIPAQNATGNWIKVVQRLPVRIALDPKELAEHPLRVGLSMDASIDLSKK

Specific function: Unknown

COG id: COG1566

COG function: function code V; Multidrug resistance efflux pump

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI1788711, Length=364, Percent_Identity=41.2087912087912, Blast_Score=278, Evalue=4e-76,
Organism=Escherichia coli, GI1789041, Length=361, Percent_Identity=43.4903047091413, Blast_Score=275, Evalue=4e-75,
Organism=Escherichia coli, GI1790519, Length=364, Percent_Identity=31.043956043956, Blast_Score=136, Evalue=3e-33,
Organism=Escherichia coli, GI87081951, Length=339, Percent_Identity=28.3185840707965, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789637, Length=335, Percent_Identity=26.5671641791045, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789900, Length=290, Percent_Identity=25.8620689655172, Blast_Score=69, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005694
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 40341; Mature: 40210

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTESAQVTASDVDDDALKAKRKKLLSIFALVIVIVAILYAIWFFFFNHTVSTDNAYVGAE
CCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCH
TAQITSMVTGQVAEIRVHDTQQVHKGDILAQVDPRDAQIALSQAQAMLAKAQRQYRQTEA
HHHHHHHHCCCEEEEEECCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
NSKSLNSQVFVSDDGIASAQAQVGKAQADYNNAIEELKRRQTLEQSGAISKEELSTAQTA
CCCCCCCEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AQTAKAALDVAKAAVSQAQSSRKAAQSNLAANQALIQGASENSAPDVLSAEANVQQAQLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHH
LERTVIRSPVDGVITGRNIQVGQRVAPGSVLMKIVPLSALYVDANFKESQLSKVRVGQAA
HHHHHHHCCCCCEEECCCEECCCCCCCHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCHH
TLTSDLYGSDVEYHGKVIGFSGGTGSAFALIPAQNATGNWIKVVQRLPVRIALDPKELAE
HHHHHHCCCCCEECCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEECHHHHHC
HPLRVGLSMDASIDLSKK
CHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TESAQVTASDVDDDALKAKRKKLLSIFALVIVIVAILYAIWFFFFNHTVSTDNAYVGAE
CCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCH
TAQITSMVTGQVAEIRVHDTQQVHKGDILAQVDPRDAQIALSQAQAMLAKAQRQYRQTEA
HHHHHHHHCCCEEEEEECCCHHHHCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
NSKSLNSQVFVSDDGIASAQAQVGKAQADYNNAIEELKRRQTLEQSGAISKEELSTAQTA
CCCCCCCEEEECCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHH
AQTAKAALDVAKAAVSQAQSSRKAAQSNLAANQALIQGASENSAPDVLSAEANVQQAQLD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCCHHHHHHH
LERTVIRSPVDGVITGRNIQVGQRVAPGSVLMKIVPLSALYVDANFKESQLSKVRVGQAA
HHHHHHHCCCCCEEECCCEECCCCCCCHHHHHHHHHHEEEEEECCCCHHHHHHHHCCCHH
TLTSDLYGSDVEYHGKVIGFSGGTGSAFALIPAQNATGNWIKVVQRLPVRIALDPKELAE
HHHHHHCCCCCEECCEEEEECCCCCCEEEEEECCCCCCHHHHHHHHCCCEEEECHHHHHC
HPLRVGLSMDASIDLSKK
CHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]