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The map label for this gene is argB

Identifier: 50084112

GI number: 50084112

Start: 886897

End: 887808

Strand: Direct

Name: argB

Synonym: ACIAD0903

Alternate gene names: 50084112

Gene position: 886897-887808 (Clockwise)

Preceding gene: 50084111

Following gene: 50084113

Centisome position: 24.65

GC content: 44.08

Gene sequence:

>912_bases
ATGCCACATCAGCATAAAGGTATCGATAAGGCAAAAATTTTGACTGAAGCTTTACCTTATATTCAACGTTTTTCTGGTAA
AACGCTGGTGGTCAAATATGGCGGTAATGCCATGACAGATCCTGAGCTTGAAAGCTCATTTGCCCGTGATATTGTACTGC
TTAAGACGGTCGGTCTGAATCCAATTGTGGTTCATGGTGGTGGCCCGCAGGTAGATTCATTACTCAAACGTTTAGGACAA
GTTTCTGATCGTATTGATGGAATGCGCGTGACCGATGAAGCGACCATGGAAGTGGTTGAAATGGTTTTGGGTGGTAGCGT
AAATAAGTCGATTGTCAATCTGATCAATCAACACGGTGGTCGTGCGATTGGCTTGACGGGTAAAGACGGCAATTTGATTC
GTGCACGTAAGCTACTCATGGAAAAACATGATGAACAGGGCGATATCAAGCATATCGATTTGGGCTTGGTAGGTGAAGTC
GTGGGCATCAAGACAGATGTACTCGAAATGTTTACCCAAAGTGATTTTATTCCGGTGATTGCGCCGTTAGGCGTTGATGA
AAGTGGCAATACCTACAATATCAATGCAGACTTGGTGGCTGGTAAGGTCGCAGAAGCATTAGGGGCAGAAAAACTGATTC
TTCTGACCAATATTTCAGGTGTTTTGGACGAAAACAAAAACCTTTTGACAGGGTTGTCCACACAAGAAGTAGACCGTTTG
ATTGCAACGGGCGTGATTTATGGAGGAATGATTCCGAAAGTTGGATGTGCATTAGATGCCGTAAAAGGCGGTGTAGTAAG
TGCACATATTGTGGATGGACGTGTTCCACATGCGACATTACTTGAAATCTTTACCGACCATGGCGTTGGTACCCTCATTA
CCAATCGTCTGCATGCTAAGTCAGAGCATTAA

Upstream 100 bases:

>100_bases
CAGCGTTTAGCTGAAATCAGACAAATATTTATCGTCATGCTGCAAAAGCAATACCCTAACATTGCACATGATCTTTCACA
GGCTTATTAAGGAGAGGCGA

Downstream 100 bases:

>100_bases
ACGTATATCCGCTACATATATCAAAAAGATCACGGAATGTGATCTTTTTTTTGGCAATAATTATTGGTCATTATTTTGTC
ATCTGTGTGTTTTAGTGTAA

Product: acetylglutamate kinase

Products: NA

Alternate protein names: N-acetyl-L-glutamate 5-phosphotransferase; NAG kinase; AGK

Number of amino acids: Translated: 303; Mature: 302

Protein sequence:

>303_residues
MPHQHKGIDKAKILTEALPYIQRFSGKTLVVKYGGNAMTDPELESSFARDIVLLKTVGLNPIVVHGGGPQVDSLLKRLGQ
VSDRIDGMRVTDEATMEVVEMVLGGSVNKSIVNLINQHGGRAIGLTGKDGNLIRARKLLMEKHDEQGDIKHIDLGLVGEV
VGIKTDVLEMFTQSDFIPVIAPLGVDESGNTYNINADLVAGKVAEALGAEKLILLTNISGVLDENKNLLTGLSTQEVDRL
IATGVIYGGMIPKVGCALDAVKGGVVSAHIVDGRVPHATLLEIFTDHGVGTLITNRLHAKSEH

Sequences:

>Translated_303_residues
MPHQHKGIDKAKILTEALPYIQRFSGKTLVVKYGGNAMTDPELESSFARDIVLLKTVGLNPIVVHGGGPQVDSLLKRLGQ
VSDRIDGMRVTDEATMEVVEMVLGGSVNKSIVNLINQHGGRAIGLTGKDGNLIRARKLLMEKHDEQGDIKHIDLGLVGEV
VGIKTDVLEMFTQSDFIPVIAPLGVDESGNTYNINADLVAGKVAEALGAEKLILLTNISGVLDENKNLLTGLSTQEVDRL
IATGVIYGGMIPKVGCALDAVKGGVVSAHIVDGRVPHATLLEIFTDHGVGTLITNRLHAKSEH
>Mature_302_residues
PHQHKGIDKAKILTEALPYIQRFSGKTLVVKYGGNAMTDPELESSFARDIVLLKTVGLNPIVVHGGGPQVDSLLKRLGQV
SDRIDGMRVTDEATMEVVEMVLGGSVNKSIVNLINQHGGRAIGLTGKDGNLIRARKLLMEKHDEQGDIKHIDLGLVGEVV
GIKTDVLEMFTQSDFIPVIAPLGVDESGNTYNINADLVAGKVAEALGAEKLILLTNISGVLDENKNLLTGLSTQEVDRLI
ATGVIYGGMIPKVGCALDAVKGGVVSAHIVDGRVPHATLLEIFTDHGVGTLITNRLHAKSEH

Specific function: Arginine biosynthesis; second step. [C]

COG id: COG0548

COG function: function code E; Acetylglutamate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetylglutamate kinase family

Homologues:

Organism=Escherichia coli, GI145693208, Length=235, Percent_Identity=31.4893617021277, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789181, Length=284, Percent_Identity=26.7605633802817, Blast_Score=89, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6320913, Length=296, Percent_Identity=29.3918918918919, Blast_Score=87, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGB_ACIAD (Q6FDQ8)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045622.1
- ProteinModelPortal:   Q6FDQ8
- SMR:   Q6FDQ8
- STRING:   Q6FDQ8
- GeneID:   2877974
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0903
- NMPDR:   fig|62977.3.peg.904
- eggNOG:   COG0548
- HOGENOM:   HBG497643
- OMA:   MDIVEMV
- PhylomeDB:   Q6FDQ8
- ProtClustDB:   PRK00942
- BioCyc:   ASP62977:ACIAD0903-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00082_B
- InterPro:   IPR004662
- InterPro:   IPR001048
- Gene3D:   G3DSA:3.40.1160.10
- PIRSF:   PIRSF000728
- TIGRFAMs:   TIGR00761

Pfam domain/function: PF00696 AA_kinase; SSF53633 Aa_kinase

EC number: =2.7.2.8

Molecular weight: Translated: 32306; Mature: 32175

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: NA

Important sites: BINDING 89-89 BINDING 193-193

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPHQHKGIDKAKILTEALPYIQRFSGKTLVVKYGGNAMTDPELESSFARDIVLLKTVGLN
CCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHEEEEEECCCC
PIVVHGGGPQVDSLLKRLGQVSDRIDGMRVTDEATMEVVEMVLGGSVNKSIVNLINQHGG
EEEEECCCCCHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
RAIGLTGKDGNLIRARKLLMEKHDEQGDIKHIDLGLVGEVVGIKTDVLEMFTQSDFIPVI
EEEEEECCCCCHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEE
APLGVDESGNTYNINADLVAGKVAEALGAEKLILLTNISGVLDENKNLLTGLSTQEVDRL
EECCCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEECCCHHHCCCCCCEECCCHHHHHHH
IATGVIYGGMIPKVGCALDAVKGGVVSAHIVDGRVPHATLLEIFTDHGVGTLITNRLHAK
HHHHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCC
SEH
CCC
>Mature Secondary Structure 
PHQHKGIDKAKILTEALPYIQRFSGKTLVVKYGGNAMTDPELESSFARDIVLLKTVGLN
CCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHEEEEEECCCC
PIVVHGGGPQVDSLLKRLGQVSDRIDGMRVTDEATMEVVEMVLGGSVNKSIVNLINQHGG
EEEEECCCCCHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHCCCCCHHHHHHHHHCCC
RAIGLTGKDGNLIRARKLLMEKHDEQGDIKHIDLGLVGEVVGIKTDVLEMFTQSDFIPVI
EEEEEECCCCCHHHHHHHHHHHCCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCEEEE
APLGVDESGNTYNINADLVAGKVAEALGAEKLILLTNISGVLDENKNLLTGLSTQEVDRL
EECCCCCCCCEEEECHHHHHHHHHHHCCCCEEEEEECCCHHHCCCCCCEECCCHHHHHHH
IATGVIYGGMIPKVGCALDAVKGGVVSAHIVDGRVPHATLLEIFTDHGVGTLITNRLHAK
HHHHHHHCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCCHHHHHHHHHCC
SEH
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA