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The map label for this gene is minC

Identifier: 50084105

GI number: 50084105

Start: 878889

End: 879611

Strand: Reverse

Name: minC

Synonym: ACIAD0895

Alternate gene names: 50084105

Gene position: 879611-878889 (Counterclockwise)

Preceding gene: 50084106

Following gene: 50084104

Centisome position: 24.44

GC content: 39.56

Gene sequence:

>723_bases
ATGGCTGATATACGGATTACAGGCAGAATGGTTAATTTTACCCGATTAACCTTCGATACCAATGATCATGATGCCATCCG
ACAACAACTTACTTCTATTTTAAATGAAGGCTCGTATCAAGGTACAGTCGTCATTCTCGATAGTACAGTCGAGCAAGAAT
TAATTGCATTGATTCAATTGCTGATCAGTCTTGGCTTACAACCTATGGCTGTCATTGACGGTATTTTGAGTGACGAAGCA
AAAGCGATTCAGTTTCCGGTGTTGCCAGCAGATCAGCCTCTACAACGTATCAAGGCATCCAAAGAAGAAATTACCGTCAT
TGCTACACCTAAAGCAGCAGATACAACTCCTGAAACAAAAACACCCATAACAAAAACAGCGATTGCACACAAAACCTCAT
ACCATGATGAAATTTTGCGTACAGGACAATGCTTGGTGCAGGATCATGGCGATATTATTTTAAATGCTGGCATGAACAGT
GGTTCTGAAGTAATTGCATCAGGTAATATTCATATTTATGGTAATGTTCGTGGTCGAATTATCGCTGGTGCTGGTGGTAA
TCCCTCTGCACGTATTTTCTGTCATGCACTGGAAGCTGAACTTGTTTCAATTGCTGGGACGTATTGTGTTGCAGAAGACA
TACCAAAAGATGTATTAAAGAAGTCTGTACATATTTATCTAAATGATAACCAAGAACTTGAATTTCGGGCGTTGGAATTT
TAA

Upstream 100 bases:

>100_bases
TTTACCTAGAGAATTCAGTTAATTTGTTCTAGCATCTGGTCTATTTACTCAATATAACTTCAACGTCCAACAACCCGTCA
GAAGTTCTTAAGGAATAATT

Downstream 100 bases:

>100_bases
GGTATAAATTAAGCACCTGAAAAGCCCGTAAAAAGCGGGTGTATGACCATAATAGGAGTGGATTCGGTGGCCAAAATTGT
TGTCGTAACATCAGGCAAAG

Product: cell division inhibitor, inhibits ftsZ ring formation

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 240; Mature: 239

Protein sequence:

>240_residues
MADIRITGRMVNFTRLTFDTNDHDAIRQQLTSILNEGSYQGTVVILDSTVEQELIALIQLLISLGLQPMAVIDGILSDEA
KAIQFPVLPADQPLQRIKASKEEITVIATPKAADTTPETKTPITKTAIAHKTSYHDEILRTGQCLVQDHGDIILNAGMNS
GSEVIASGNIHIYGNVRGRIIAGAGGNPSARIFCHALEAELVSIAGTYCVAEDIPKDVLKKSVHIYLNDNQELEFRALEF

Sequences:

>Translated_240_residues
MADIRITGRMVNFTRLTFDTNDHDAIRQQLTSILNEGSYQGTVVILDSTVEQELIALIQLLISLGLQPMAVIDGILSDEA
KAIQFPVLPADQPLQRIKASKEEITVIATPKAADTTPETKTPITKTAIAHKTSYHDEILRTGQCLVQDHGDIILNAGMNS
GSEVIASGNIHIYGNVRGRIIAGAGGNPSARIFCHALEAELVSIAGTYCVAEDIPKDVLKKSVHIYLNDNQELEFRALEF
>Mature_239_residues
ADIRITGRMVNFTRLTFDTNDHDAIRQQLTSILNEGSYQGTVVILDSTVEQELIALIQLLISLGLQPMAVIDGILSDEAK
AIQFPVLPADQPLQRIKASKEEITVIATPKAADTTPETKTPITKTAIAHKTSYHDEILRTGQCLVQDHGDIILNAGMNSG
SEVIASGNIHIYGNVRGRIIAGAGGNPSARIFCHALEAELVSIAGTYCVAEDIPKDVLKKSVHIYLNDNQELEFRALEF

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=120, Percent_Identity=40, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_ACIAD (Q6FDR5)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045615.1
- ProteinModelPortal:   Q6FDR5
- STRING:   Q6FDR5
- GeneID:   2879539
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0895
- NMPDR:   fig|62977.3.peg.897
- eggNOG:   COG0850
- HOGENOM:   HBG399077
- OMA:   KDARIFC
- ProtClustDB:   CLSK830533
- BioCyc:   ASP62977:ACIAD0895-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 26116; Mature: 25985

Theoretical pI: Translated: 4.94; Mature: 4.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADIRITGRMVNFTRLTFDTNDHDAIRQQLTSILNEGSYQGTVVILDSTVEQELIALIQL
CCCEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHH
LISLGLQPMAVIDGILSDEAKAIQFPVLPADQPLQRIKASKEEITVIATPKAADTTPETK
HHHCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCC
TPITKTAIAHKTSYHDEILRTGQCLVQDHGDIILNAGMNSGSEVIASGNIHIYGNVRGRI
CCCHHHHHHHCCCHHHHHHHCCCEEEECCCCEEEECCCCCCCEEEEECCEEEEECCCEEE
IAGAGGNPSARIFCHALEAELVSIAGTYCVAEDIPKDVLKKSVHIYLNDNQELEFRALEF
EECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHCEEEEEECCCCCEEEEEECC
>Mature Secondary Structure 
ADIRITGRMVNFTRLTFDTNDHDAIRQQLTSILNEGSYQGTVVILDSTVEQELIALIQL
CCEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHCCCCCCEEEEEEECCHHHHHHHHHHH
LISLGLQPMAVIDGILSDEAKAIQFPVLPADQPLQRIKASKEEITVIATPKAADTTPETK
HHHCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCC
TPITKTAIAHKTSYHDEILRTGQCLVQDHGDIILNAGMNSGSEVIASGNIHIYGNVRGRI
CCCHHHHHHHCCCHHHHHHHCCCEEEECCCCEEEECCCCCCCEEEEECCEEEEECCCEEE
IAGAGGNPSARIFCHALEAELVSIAGTYCVAEDIPKDVLKKSVHIYLNDNQELEFRALEF
EECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHCEEEEEECCCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA