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The map label for this gene is minD [H]

Identifier: 50084104

GI number: 50084104

Start: 878010

End: 878846

Strand: Reverse

Name: minD [H]

Synonym: ACIAD0894

Alternate gene names: 50084104

Gene position: 878846-878010 (Counterclockwise)

Preceding gene: 50084105

Following gene: 50084103

Centisome position: 24.42

GC content: 40.26

Gene sequence:

>837_bases
ATGACCATAATAGGAGTGGATTCGGTGGCCAAAATTGTTGTCGTAACATCAGGCAAAGGTGGTGTAGGTAAAACTACTAC
AAGTGCATCTTTTGCAACAGGTTTAGCCCTACGTGGTCATAAAACTGTTGTGATTGATTTTGACGTAGGTTTACGTAATC
TAGACCTCATCATGGGATGCGAGCGCCGTGTTGTTTATGATTTTGTCAATGTGATTAACAACGAAGCACGCTTACAGCAG
GCTTTAATTCGCGATAAAGACATTGAAAATTTGTATATTTTACCTGCGTCACAAACACGTGATAAAGATGCCTTGACCGA
CGAAGGCGTCGCCCGTGTAATCGAAGAATTATCTCAAGAATTTGATTATATTATTTGTGACTCACCTGCGGGTATTGAGC
GCGGTGCTATTTTAGCCATGTATCATGCAGATGAAGCGATTATTGTGACGAATCCAGAAATTTCTTCTGTACGTGACTCT
GACCGTATTATTGGCATGCTAGATAGTAAAACTAAAAAAGTAGAGCAAAATGAAGGACGTGTGCGTAAACATTTATGTAT
TACGCGCTTCAACCCTGAACGTGCAGATCGTCAAGAAATGTTAACAATCGATGATATTTCTAAAGATATTTTGCGTATTC
CAACGTTAGGTGTCATTCCAGAATGTCCTAGCGTATTACAAGCTTCAAACGAAGGAAAACCTGTAGTTCTTTATACAGAA
TCAAAATCAGGTCAGGCTTACGATGACCTTGTTGCGCGTTTCTTGGGAGAAGAACGTCCTTATCGACATATTACCGTTCA
ACCGAAAAGCTGGTTGGCACGATTATTTGGAGCATAA

Upstream 100 bases:

>100_bases
TGTACATATTTATCTAAATGATAACCAAGAACTTGAATTTCGGGCGTTGGAATTTTAAGGTATAAATTAAGCACCTGAAA
AGCCCGTAAAAAGCGGGTGT

Downstream 100 bases:

>100_bases
GCATGGCAGGATTCTGGAGCAAAATATTCGGTAATGATGAAAAGCCTTCGAGCGCCCAAACAGCCAAAGATCGTTTAAAA
GTTATCGTGGCATCTGAGCA

Product: cell division inhibitor, a membrane ATPase,activates minC

Products: NA

Alternate protein names: Cell division inhibitor minD [H]

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MTIIGVDSVAKIVVVTSGKGGVGKTTTSASFATGLALRGHKTVVIDFDVGLRNLDLIMGCERRVVYDFVNVINNEARLQQ
ALIRDKDIENLYILPASQTRDKDALTDEGVARVIEELSQEFDYIICDSPAGIERGAILAMYHADEAIIVTNPEISSVRDS
DRIIGMLDSKTKKVEQNEGRVRKHLCITRFNPERADRQEMLTIDDISKDILRIPTLGVIPECPSVLQASNEGKPVVLYTE
SKSGQAYDDLVARFLGEERPYRHITVQPKSWLARLFGA

Sequences:

>Translated_278_residues
MTIIGVDSVAKIVVVTSGKGGVGKTTTSASFATGLALRGHKTVVIDFDVGLRNLDLIMGCERRVVYDFVNVINNEARLQQ
ALIRDKDIENLYILPASQTRDKDALTDEGVARVIEELSQEFDYIICDSPAGIERGAILAMYHADEAIIVTNPEISSVRDS
DRIIGMLDSKTKKVEQNEGRVRKHLCITRFNPERADRQEMLTIDDISKDILRIPTLGVIPECPSVLQASNEGKPVVLYTE
SKSGQAYDDLVARFLGEERPYRHITVQPKSWLARLFGA
>Mature_277_residues
TIIGVDSVAKIVVVTSGKGGVGKTTTSASFATGLALRGHKTVVIDFDVGLRNLDLIMGCERRVVYDFVNVINNEARLQQA
LIRDKDIENLYILPASQTRDKDALTDEGVARVIEELSQEFDYIICDSPAGIERGAILAMYHADEAIIVTNPEISSVRDSD
RIIGMLDSKTKKVEQNEGRVRKHLCITRFNPERADRQEMLTIDDISKDILRIPTLGVIPECPSVLQASNEGKPVVLYTES
KSGQAYDDLVARFLGEERPYRHITVQPKSWLARLFGA

Specific function: ATPase required for the correct placement of the division site. Cell division inhibitors minC and minD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to desta

COG id: COG2894

COG function: function code D; Septum formation inhibitor-activating ATPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the parA family. MinD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787423, Length=271, Percent_Identity=64.5756457564576, Blast_Score=361, Evalue=1e-101,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR010223 [H]

Pfam domain/function: PF01656 CbiA [H]

EC number: NA

Molecular weight: Translated: 30832; Mature: 30700

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIIGVDSVAKIVVVTSGKGGVGKTTTSASFATGLALRGHKTVVIDFDVGLRNLDLIMGC
CEEEECCCEEEEEEEECCCCCCCCCCCCCHHHHCEEECCCEEEEEEECCCCCCCHHHHCC
ERRVVYDFVNVINNEARLQQALIRDKDIENLYILPASQTRDKDALTDEGVARVIEELSQE
CHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
FDYIICDSPAGIERGAILAMYHADEAIIVTNPEISSVRDSDRIIGMLDSKTKKVEQNEGR
CCEEEECCCCCCCCCCEEEEEECCCEEEEECCCHHCCCCCCCEEEEECCCHHHHHHCCCH
VRKHLCITRFNPERADRQEMLTIDDISKDILRIPTLGVIPECPSVLQASNEGKPVVLYTE
HHHEEEEEECCCCCCCHHHEEEHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEEEEEC
SKSGQAYDDLVARFLGEERPYRHITVQPKSWLARLFGA
CCCCCHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHCC
>Mature Secondary Structure 
TIIGVDSVAKIVVVTSGKGGVGKTTTSASFATGLALRGHKTVVIDFDVGLRNLDLIMGC
EEEECCCEEEEEEEECCCCCCCCCCCCCHHHHCEEECCCEEEEEEECCCCCCCHHHHCC
ERRVVYDFVNVINNEARLQQALIRDKDIENLYILPASQTRDKDALTDEGVARVIEELSQE
CHHHHHHHHHHHCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
FDYIICDSPAGIERGAILAMYHADEAIIVTNPEISSVRDSDRIIGMLDSKTKKVEQNEGR
CCEEEECCCCCCCCCCEEEEEECCCEEEEECCCHHCCCCCCCEEEEECCCHHHHHHCCCH
VRKHLCITRFNPERADRQEMLTIDDISKDILRIPTLGVIPECPSVLQASNEGKPVVLYTE
HHHEEEEEECCCCCCCHHHEEEHHHHHHHHHHCCCCCCCCCCHHHHHCCCCCCEEEEEEC
SKSGQAYDDLVARFLGEERPYRHITVQPKSWLARLFGA
CCCCCHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10710307 [H]