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The map label for this gene is aat

Identifier: 50084099

GI number: 50084099

Start: 872087

End: 872812

Strand: Reverse

Name: aat

Synonym: ACIAD0889

Alternate gene names: 50084099

Gene position: 872812-872087 (Counterclockwise)

Preceding gene: 50084100

Following gene: 50084098

Centisome position: 24.25

GC content: 39.53

Gene sequence:

>726_bases
ATGATTCTTCCATCGATGTATGTTTTTCCCGATCCACCCGAAGCAGATCCAGAAGGTCAGGGACTCATCTGTATTGGTGC
AGACCTGGAACCTTCGACGCTATTCGAAGCTTATACGCACGGATTATTTCCTTGGTTCAATGAAGGTGATCCAATTTGTT
GGTGGAGTCCAGAACCACGTTGTGTAATCTATCCAGAGCAGTATCAACCCAGTAAAACCTTAATTCGTAGTATGAAAAAG
TACGATTATCAAATCACCATGAATCGCGCTTTTGAAAAAGTAATACGTTCGTGTGCATTACCACGTAACTACACCAATGA
AACATGGATTTCAGAAGATATTGTACAAGGGTATGTGGAGTTATTTAAGGCAGGTTATGCTTATAGTGTAGAGGTATGGG
AAAACGATCAATTGATTGGCGGTTTATATGGGGTAAATATTGGTAAAGGTTGTTTCGGCGAATCGATGTTTAGTTTGCGT
ACAGACACTTCAAAAATTGCATTTTACACACTAATGCTGATTGGACAGGAAAATCAGGTTCCTTGGGTGGACTGTCAATT
GGTCAATGACCATCTAATTAGTCTGGGTGCCTGTACACTTTCTCGACAAGCCTACTTAAAATCGTTACAAGATGTAATTA
TTCAGCCCCCTATCAATTGGAAAAGATATCAAGAACGTGTATTTTCAAGTAAAAGAATTGCCCAAAATGCAAAACTAACC
GAATGA

Upstream 100 bases:

>100_bases
CGCAGATTTTTATTTAGATAGCATCTAAATTTAATATTTATTCTCATCCTATAAAAAAGATCGGCTAAAATGAAGCCGAT
CTTTTTATATCTCCCCTGCC

Downstream 100 bases:

>100_bases
TAACAATGAGGGGGCTGTATCACAATGAAATCATACCAACCAAAGTCCCTTCTTAACGACTTACAATATTATATTACCCC
ACCACACGATTGCAGTTATC

Product: leucyl/phenylalanyl-tRNA--protein transferase

Products: NA

Alternate protein names: L/F-transferase; Leucyltransferase; Phenyalanyltransferase

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MILPSMYVFPDPPEADPEGQGLICIGADLEPSTLFEAYTHGLFPWFNEGDPICWWSPEPRCVIYPEQYQPSKTLIRSMKK
YDYQITMNRAFEKVIRSCALPRNYTNETWISEDIVQGYVELFKAGYAYSVEVWENDQLIGGLYGVNIGKGCFGESMFSLR
TDTSKIAFYTLMLIGQENQVPWVDCQLVNDHLISLGACTLSRQAYLKSLQDVIIQPPINWKRYQERVFSSKRIAQNAKLT
E

Sequences:

>Translated_241_residues
MILPSMYVFPDPPEADPEGQGLICIGADLEPSTLFEAYTHGLFPWFNEGDPICWWSPEPRCVIYPEQYQPSKTLIRSMKK
YDYQITMNRAFEKVIRSCALPRNYTNETWISEDIVQGYVELFKAGYAYSVEVWENDQLIGGLYGVNIGKGCFGESMFSLR
TDTSKIAFYTLMLIGQENQVPWVDCQLVNDHLISLGACTLSRQAYLKSLQDVIIQPPINWKRYQERVFSSKRIAQNAKLT
E
>Mature_241_residues
MILPSMYVFPDPPEADPEGQGLICIGADLEPSTLFEAYTHGLFPWFNEGDPICWWSPEPRCVIYPEQYQPSKTLIRSMKK
YDYQITMNRAFEKVIRSCALPRNYTNETWISEDIVQGYVELFKAGYAYSVEVWENDQLIGGLYGVNIGKGCFGESMFSLR
TDTSKIAFYTLMLIGQENQVPWVDCQLVNDHLISLGACTLSRQAYLKSLQDVIIQPPINWKRYQERVFSSKRIAQNAKLT
E

Specific function: Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine

COG id: COG2360

COG function: function code O; Leu/Phe-tRNA-protein transferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the L/F-transferase family

Homologues:

Organism=Escherichia coli, GI1787111, Length=207, Percent_Identity=44.4444444444444, Blast_Score=187, Evalue=8e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LFTR_ACIAD (Q6FDS1)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045609.1
- ProteinModelPortal:   Q6FDS1
- SMR:   Q6FDS1
- STRING:   Q6FDS1
- GeneID:   2878569
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0889
- NMPDR:   fig|62977.3.peg.857
- eggNOG:   COG2360
- HOGENOM:   HBG485363
- OMA:   GEPILWW
- PhylomeDB:   Q6FDS1
- ProtClustDB:   PRK00301
- BioCyc:   ASP62977:ACIAD0889-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00688
- InterPro:   IPR016181
- InterPro:   IPR004616
- TIGRFAMs:   TIGR00667

Pfam domain/function: PF03588 Leu_Phe_trans; SSF55729 Acyl_CoA_acyltransferase

EC number: =2.3.2.6

Molecular weight: Translated: 27699; Mature: 27699

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILPSMYVFPDPPEADPEGQGLICIGADLEPSTLFEAYTHGLFPWFNEGDPICWWSPEPR
CCCCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCC
CVIYPEQYQPSKTLIRSMKKYDYQITMNRAFEKVIRSCALPRNYTNETWISEDIVQGYVE
EEECCCCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LFKAGYAYSVEVWENDQLIGGLYGVNIGKGCFGESMFSLRTDTSKIAFYTLMLIGQENQV
HHHCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCHHHHCCCCHHHEEEEEEEEECCCCC
PWVDCQLVNDHLISLGACTLSRQAYLKSLQDVIIQPPINWKRYQERVFSSKRIAQNAKLT
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCC
E
C
>Mature Secondary Structure
MILPSMYVFPDPPEADPEGQGLICIGADLEPSTLFEAYTHGLFPWFNEGDPICWWSPEPR
CCCCCEEECCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCEEEECCCCC
CVIYPEQYQPSKTLIRSMKKYDYQITMNRAFEKVIRSCALPRNYTNETWISEDIVQGYVE
EEECCCCCCCHHHHHHHHHHCCEEEEHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
LFKAGYAYSVEVWENDQLIGGLYGVNIGKGCFGESMFSLRTDTSKIAFYTLMLIGQENQV
HHHCCCEEEEEEECCCCEEEEEEECCCCCCCCCCCHHHHCCCCHHHEEEEEEEEECCCCC
PWVDCQLVNDHLISLGACTLSRQAYLKSLQDVIIQPPINWKRYQERVFSSKRIAQNAKLT
CEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCC
E
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA