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The map label for this gene is trxB [H]

Identifier: 50084100

GI number: 50084100

Start: 872885

End: 873832

Strand: Reverse

Name: trxB [H]

Synonym: ACIAD0890

Alternate gene names: 50084100

Gene position: 873832-872885 (Counterclockwise)

Preceding gene: 50084102

Following gene: 50084099

Centisome position: 24.28

GC content: 43.14

Gene sequence:

>948_bases
ATGAGCGCTCGTCACTCACGGTTAATTATCTTAGGTTCTGGTCCTGCAGGTTATAGCGCTGCTGTTTATGCAGCACGTGC
AAATCTCAAGCCAACCCTGATTGCTGGTTTACAACTGGGTGGTCAGTTGACAACGACCACTGAAGTCGACAACTGGCCTG
GTGATCCTGAAGGTTTAACTGGGCCTGCTCTGATGGAACGTATGCAAGCACATGCAGAACGTTTTGGTACAGAGATCGTT
TACGATCACATCAATGAAGTCGACTTAAAAACCCGTCCTTTTGTTCTTAAAGGCGATATGGATGAATATACGTGTGACGC
GCTCATTATTGCGACTGGTGCGACTGCACAATATTTAGGTTTAGAATCTGAAGCCGCCTTTATGGGTCAAGGTGTAAGTG
CTTGTGCGACCTGTGATGGTTTTTTCTATAAAAACCAGAAAGTCATGGTTGTCGGTGGTGGTAATACTGCAGTTGAAGAA
GCTTTGTATTTATCCAATATTGCCTCACATGTCACACTGGTGCATCGCCGTGATAGCTTGCGCTCTGAAAAAATCTTGCA
AGATCATCTTTTTGCCAAAGAAAAAGAAGGCAAAATTAGCATCGTATGGAACCATCAAGTAGATGAAGTATTGGGTGACA
CTACTGGTGTAACTTCGGTACGTTTAAAATCGACTCAAGATGAATCAACTCAAACCATCGATGTACAAGGTTTATTTGTG
GCTATTGGTCATAAACCAAATACAGAAATGTTTAAAGACCAACTTGAATTACGCGATGGTTATATTCAGGTACAAAGTGG
AACCAAGGGAAATGCCACTGCAACTTCTGTAGCGGGTGTATTTGCTGCGGGTGATGTGGCCGATAACATCTATCGTCAGG
CTATTACCTCTGCTGGTTCAGGTTGTATGGCAGCTTTGGACGCAGATTTTTATTTAGATAGCATCTAA

Upstream 100 bases:

>100_bases
TCGATTTAATTGATCAATATTATCAACATCAAATCACAGCCATTCCGCTTCAGTTTCACGTATAATTCTAAAAATTTCGA
TATAAATAAGGATACCTTTC

Downstream 100 bases:

>100_bases
ATTTAATATTTATTCTCATCCTATAAAAAAGATCGGCTAAAATGAAGCCGATCTTTTTATATCTCCCCTGCCATGATTCT
TCCATCGATGTATGTTTTTC

Product: thioredoxin reductase 1

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 315; Mature: 314

Protein sequence:

>315_residues
MSARHSRLIILGSGPAGYSAAVYAARANLKPTLIAGLQLGGQLTTTTEVDNWPGDPEGLTGPALMERMQAHAERFGTEIV
YDHINEVDLKTRPFVLKGDMDEYTCDALIIATGATAQYLGLESEAAFMGQGVSACATCDGFFYKNQKVMVVGGGNTAVEE
ALYLSNIASHVTLVHRRDSLRSEKILQDHLFAKEKEGKISIVWNHQVDEVLGDTTGVTSVRLKSTQDESTQTIDVQGLFV
AIGHKPNTEMFKDQLELRDGYIQVQSGTKGNATATSVAGVFAAGDVADNIYRQAITSAGSGCMAALDADFYLDSI

Sequences:

>Translated_315_residues
MSARHSRLIILGSGPAGYSAAVYAARANLKPTLIAGLQLGGQLTTTTEVDNWPGDPEGLTGPALMERMQAHAERFGTEIV
YDHINEVDLKTRPFVLKGDMDEYTCDALIIATGATAQYLGLESEAAFMGQGVSACATCDGFFYKNQKVMVVGGGNTAVEE
ALYLSNIASHVTLVHRRDSLRSEKILQDHLFAKEKEGKISIVWNHQVDEVLGDTTGVTSVRLKSTQDESTQTIDVQGLFV
AIGHKPNTEMFKDQLELRDGYIQVQSGTKGNATATSVAGVFAAGDVADNIYRQAITSAGSGCMAALDADFYLDSI
>Mature_314_residues
SARHSRLIILGSGPAGYSAAVYAARANLKPTLIAGLQLGGQLTTTTEVDNWPGDPEGLTGPALMERMQAHAERFGTEIVY
DHINEVDLKTRPFVLKGDMDEYTCDALIIATGATAQYLGLESEAAFMGQGVSACATCDGFFYKNQKVMVVGGGNTAVEEA
LYLSNIASHVTLVHRRDSLRSEKILQDHLFAKEKEGKISIVWNHQVDEVLGDTTGVTSVRLKSTQDESTQTIDVQGLFVA
IGHKPNTEMFKDQLELRDGYIQVQSGTKGNATATSVAGVFAAGDVADNIYRQAITSAGSGCMAALDADFYLDSI

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=315, Percent_Identity=69.2063492063492, Blast_Score=457, Evalue=1e-130,
Organism=Escherichia coli, GI87081763, Length=300, Percent_Identity=29.6666666666667, Blast_Score=134, Evalue=6e-33,
Organism=Saccharomyces cerevisiae, GI6320560, Length=323, Percent_Identity=45.2012383900929, Blast_Score=275, Evalue=5e-75,
Organism=Saccharomyces cerevisiae, GI6321898, Length=322, Percent_Identity=44.4099378881988, Blast_Score=271, Evalue=1e-73,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 33775; Mature: 33644

Theoretical pI: Translated: 4.74; Mature: 4.74

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSARHSRLIILGSGPAGYSAAVYAARANLKPTLIAGLQLGGQLTTTTEVDNWPGDPEGLT
CCCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCC
GPALMERMQAHAERFGTEIVYDHINEVDLKTRPFVLKGDMDEYTCDALIIATGATAQYLG
CHHHHHHHHHHHHHHCCHHEECCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCEEEC
LESEAAFMGQGVSACATCDGFFYKNQKVMVVGGGNTAVEEALYLSNIASHVTLVHRRDSL
CCCCHHHHCCCCHHHEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHEEEEHHHHH
RSEKILQDHLFAKEKEGKISIVWNHQVDEVLGDTTGVTSVRLKSTQDESTQTIDVQGLFV
HHHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEEEE
AIGHKPNTEMFKDQLELRDGYIQVQSGTKGNATATSVAGVFAAGDVADNIYRQAITSAGS
EECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHEECCHHHHHHHHHHHHHCCC
GCMAALDADFYLDSI
CEEEEEECCEEECCC
>Mature Secondary Structure 
SARHSRLIILGSGPAGYSAAVYAARANLKPTLIAGLQLGGQLTTTTEVDNWPGDPEGLT
CCCCCEEEEEECCCCCCCEEEEEECCCCCEEEEEEEECCCEEEEEEECCCCCCCCCCCC
GPALMERMQAHAERFGTEIVYDHINEVDLKTRPFVLKGDMDEYTCDALIIATGATAQYLG
CHHHHHHHHHHHHHHCCHHEECCCCCCCCCCCCEEEECCCCCCCCCEEEEEECCCCEEEC
LESEAAFMGQGVSACATCDGFFYKNQKVMVVGGGNTAVEEALYLSNIASHVTLVHRRDSL
CCCCHHHHCCCCHHHEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHHEEEEHHHHH
RSEKILQDHLFAKEKEGKISIVWNHQVDEVLGDTTGVTSVRLKSTQDESTQTIDVQGLFV
HHHHHHHHHHHCCCCCCEEEEEECCCHHHHHCCCCCCEEEEEECCCCCCCEEEEEEEEEE
AIGHKPNTEMFKDQLELRDGYIQVQSGTKGNATATSVAGVFAAGDVADNIYRQAITSAGS
EECCCCCHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHEECCHHHHHHHHHHHHHCCC
GCMAALDADFYLDSI
CEEEEEECCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]