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The map label for this gene is cysH [H]

Identifier: 50084046

GI number: 50084046

Start: 820908

End: 821657

Strand: Reverse

Name: cysH [H]

Synonym: ACIAD0833

Alternate gene names: 50084046

Gene position: 821657-820908 (Counterclockwise)

Preceding gene: 50084048

Following gene: 50084045

Centisome position: 22.83

GC content: 41.2

Gene sequence:

>750_bases
TTGCCAGGAGCATTTATGACCGCCATTCCTACCATTGATTTGGTTGATGCACTTAATACAGAGTATGCAGACAAGTATCC
GACCGAGATTCTTGAGCTTGCTCTGAATCAAGAAGGTGAAATTGCCATTTCATTTTCTGGTGCAGAAGATGTAGTACTCA
TTGATATGGCCTCACGTTTACGTAAGCCGTTTCGTGTTTTTAGTCTGGATACAGGACGTTTACATCCAGAGACTTATCAA
TTCATTGAAACTGTCCGCAAACATTATAATATCGAGATCGAAATCTGTTTTCCCGAAGCTGAAACAGTTCAAAACTTCGT
AAAAGAAAAAGGATTGTTTAGCTTCTTTGAAGATGGTCATTCCGAATGTTGTGGTATTCGAAAAGTACAGCCACTTCGTA
AAAAACTGGCAACATTAGATGGCTGGATCACAGGTCAACGTAAAGATCAAAGCCCTGGTACTCGTAATGAAATTCCAGTT
GTTCAGGCAGATGCAGGTTTTTCAGGCCCAGGAAAACAGTTAATCAAGTATAATCCGCTTGCCAACTGGTCAAGTGCAGA
TGTATGGAATTATATTCGTATGATGGAAATTCCGTATAATCCATTGCACGAGCGTGGTTTTGTTTCGATTGGCTGTGAAC
CATGTACTCGCCCTGTTTTGCCCAACCAGCATGAACGTGAAGGTCGTTGGTGGTGGGAAGAAGCGACTAAAAAAGAATGT
GGCCTACATGCAGGCAACTTAAATAAATAA

Upstream 100 bases:

>100_bases
TCATGATTGAAAGTGCGTGAAATAGATTGATCGCACTTTTATTTCGTATAAATTAGAACCTTTATAATTTACTGCGCTAT
ATAATACGCATCCAAGCCTC

Downstream 100 bases:

>100_bases
TTTAAAAAAAACCACTGTTATTGCAGTGGTTTTTTTTATGTACTCGCTATTCAGTATAATTCGTTAGATTTATGTTGATT
AATAACGATATACTCAATAC

Product: phosphoadenosine phosphosulfate reductase

Products: NA

Alternate protein names: 3'-phosphoadenylylsulfate reductase; PAPS reductase, thioredoxin dependent; PAPS sulfotransferase; PAdoPS reductase [H]

Number of amino acids: Translated: 249; Mature: 248

Protein sequence:

>249_residues
MPGAFMTAIPTIDLVDALNTEYADKYPTEILELALNQEGEIAISFSGAEDVVLIDMASRLRKPFRVFSLDTGRLHPETYQ
FIETVRKHYNIEIEICFPEAETVQNFVKEKGLFSFFEDGHSECCGIRKVQPLRKKLATLDGWITGQRKDQSPGTRNEIPV
VQADAGFSGPGKQLIKYNPLANWSSADVWNYIRMMEIPYNPLHERGFVSIGCEPCTRPVLPNQHEREGRWWWEEATKKEC
GLHAGNLNK

Sequences:

>Translated_249_residues
MPGAFMTAIPTIDLVDALNTEYADKYPTEILELALNQEGEIAISFSGAEDVVLIDMASRLRKPFRVFSLDTGRLHPETYQ
FIETVRKHYNIEIEICFPEAETVQNFVKEKGLFSFFEDGHSECCGIRKVQPLRKKLATLDGWITGQRKDQSPGTRNEIPV
VQADAGFSGPGKQLIKYNPLANWSSADVWNYIRMMEIPYNPLHERGFVSIGCEPCTRPVLPNQHEREGRWWWEEATKKEC
GLHAGNLNK
>Mature_248_residues
PGAFMTAIPTIDLVDALNTEYADKYPTEILELALNQEGEIAISFSGAEDVVLIDMASRLRKPFRVFSLDTGRLHPETYQF
IETVRKHYNIEIEICFPEAETVQNFVKEKGLFSFFEDGHSECCGIRKVQPLRKKLATLDGWITGQRKDQSPGTRNEIPVV
QADAGFSGPGKQLIKYNPLANWSSADVWNYIRMMEIPYNPLHERGFVSIGCEPCTRPVLPNQHEREGRWWWEEATKKECG
LHAGNLNK

Specific function: Reduction of activated sulfate into sulfite [H]

COG id: COG0175

COG function: function code EH; 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PAPS reductase family. CysH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789121, Length=213, Percent_Identity=28.169014084507, Blast_Score=92, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6325425, Length=210, Percent_Identity=30, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011798
- InterPro:   IPR004511
- InterPro:   IPR002500
- InterPro:   IPR014729 [H]

Pfam domain/function: PF01507 PAPS_reduct [H]

EC number: =1.8.4.8 [H]

Molecular weight: Translated: 28363; Mature: 28231

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPGAFMTAIPTIDLVDALNTEYADKYPTEILELALNQEGEIAISFSGAEDVVLIDMASRL
CCCCHHHHCCCHHHHHHHCCHHCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEHHHHH
RKPFRVFSLDTGRLHPETYQFIETVRKHYNIEIEICFPEAETVQNFVKEKGLFSFFEDGH
CCCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCHHHHHHCCH
SECCGIRKVQPLRKKLATLDGWITGQRKDQSPGTRNEIPVVQADAGFSGPGKQLIKYNPL
HHHCCCHHHHHHHHHHHHHHCEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCC
ANWSSADVWNYIRMMEIPYNPLHERGFVSIGCEPCTRPVLPNQHEREGRWWWEEATKKEC
CCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
GLHAGNLNK
CCCCCCCCC
>Mature Secondary Structure 
PGAFMTAIPTIDLVDALNTEYADKYPTEILELALNQEGEIAISFSGAEDVVLIDMASRL
CCCHHHHCCCHHHHHHHCCHHCHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEEHHHHH
RKPFRVFSLDTGRLHPETYQFIETVRKHYNIEIEICFPEAETVQNFVKEKGLFSFFEDGH
CCCEEEEEECCCCCCHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHCCHHHHHHCCH
SECCGIRKVQPLRKKLATLDGWITGQRKDQSPGTRNEIPVVQADAGFSGPGKQLIKYNPL
HHHCCCHHHHHHHHHHHHHHCEECCCCCCCCCCCCCCCCEEEECCCCCCCCCCEEEECCC
ANWSSADVWNYIRMMEIPYNPLHERGFVSIGCEPCTRPVLPNQHEREGRWWWEEATKKEC
CCCCCCHHHHHHHHHCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
GLHAGNLNK
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA