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The map label for this gene is nadA [H]

Identifier: 50083883

GI number: 50083883

Start: 641548

End: 642612

Strand: Direct

Name: nadA [H]

Synonym: ACIAD0651

Alternate gene names: 50083883

Gene position: 641548-642612 (Clockwise)

Preceding gene: 50083882

Following gene: 50083887

Centisome position: 17.83

GC content: 43.94

Gene sequence:

>1065_bases
ATGAATGATGCGACTTTAATTGCAAATGATGCAAAAGTAATCGTGCAAGCGCATTTAGATCGTTTGGGTGAACCTAAGGA
TCATCACTTGAGTCCAGATGTAAAACAGGCCAAGTTCGATCAAATCAAGGAAGAATTAAAAAAACGTAATGCTGTTCTGG
TTGCGCATTATTATTGTGATCCTGACGTTCAGGAGCTTGCTGAGCTGACGGGAGGCTGTGTATCTGACTCTCTAGAAATG
GCACGCTTTGGTCGTGATCATGACGCTACGACCTTAGTTGTGGCTGGTGTTAAATTTATGGGCGAAACAGCCAAAATTTT
ATCTCCAGAAAAAACGATTCTGATGCCGACCCTAGAGGCAACCTGCTCACTAGATTTGGGATGTCCAGTTGATGAGTTCT
CGGCTTTTTGTGATCAACATCCAGATCATACTGTTGTGGTGTATGCCAATACCTCAGCGGCAGTGAAAGCACGTGCAGAC
TGGGTAGTAACTTCAAGTTGTGCTGTTGAAATTATTGAACATCTAGATAGTTTGGGTGAAAAGATTATCTGGGCACCAGA
TCAACATTTAGGCCGTTATATTCAAAAGAAAACTGGTGCCGAGATGTTGCTTTGGGATGGTTCTTGTATCGTGCATGAAG
AATTCCGTGCCCGTGGCATTGCCAATATGAAAGCCTTATATCCAGATGCAGCAGTGCTTGTACATCCTGAATCACCAGAA
TCGGTGGTTGAGATTGCCGATGCAGTAGGCAGTACATCGCAATTGATTAAGGCAGCACAGACTTTACCAAATGAACGTTT
GATTGTAGCCACAGATCGTGGAATCTTTTACAAGATGCAACAAGCAGTACCGCATAAGATTTTGGTGGAAGCACCAACTG
CGGGCGAAGGTGCTACTTGTCGCTCATGTGCACATTGCCCGTGGATGGCAATGAATGAGCTGGATGGTATTTTGCATGTT
TTACAGCATGCCGATCAGGAAATTCATGTTGATCCACAGCTCGCTGAACGTGCAAAACTTCCTTTAGATCGAATGTTGAG
CTTTAGTGCATCGTTGAAGCGTTAA

Upstream 100 bases:

>100_bases
TTTAAATTTGGTTTTTTATCAGCTCATATTATCTTTACATGCTGAGCTGTTGTACGTTAACGCTCGCAAAATGCTAGCTA
GAGAATAGAGAAGACGTTTT

Downstream 100 bases:

>100_bases
AATGCTTGTTAAATATACATTTGATAACGTTTTTTCACTTTTTTTAACTCTAGGTGTTGACGTGGTTGAGCGTCCCGCCT
AGAATGCACACCGTACCGCA

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 354; Mature: 354

Protein sequence:

>354_residues
MNDATLIANDAKVIVQAHLDRLGEPKDHHLSPDVKQAKFDQIKEELKKRNAVLVAHYYCDPDVQELAELTGGCVSDSLEM
ARFGRDHDATTLVVAGVKFMGETAKILSPEKTILMPTLEATCSLDLGCPVDEFSAFCDQHPDHTVVVYANTSAAVKARAD
WVVTSSCAVEIIEHLDSLGEKIIWAPDQHLGRYIQKKTGAEMLLWDGSCIVHEEFRARGIANMKALYPDAAVLVHPESPE
SVVEIADAVGSTSQLIKAAQTLPNERLIVATDRGIFYKMQQAVPHKILVEAPTAGEGATCRSCAHCPWMAMNELDGILHV
LQHADQEIHVDPQLAERAKLPLDRMLSFSASLKR

Sequences:

>Translated_354_residues
MNDATLIANDAKVIVQAHLDRLGEPKDHHLSPDVKQAKFDQIKEELKKRNAVLVAHYYCDPDVQELAELTGGCVSDSLEM
ARFGRDHDATTLVVAGVKFMGETAKILSPEKTILMPTLEATCSLDLGCPVDEFSAFCDQHPDHTVVVYANTSAAVKARAD
WVVTSSCAVEIIEHLDSLGEKIIWAPDQHLGRYIQKKTGAEMLLWDGSCIVHEEFRARGIANMKALYPDAAVLVHPESPE
SVVEIADAVGSTSQLIKAAQTLPNERLIVATDRGIFYKMQQAVPHKILVEAPTAGEGATCRSCAHCPWMAMNELDGILHV
LQHADQEIHVDPQLAERAKLPLDRMLSFSASLKR
>Mature_354_residues
MNDATLIANDAKVIVQAHLDRLGEPKDHHLSPDVKQAKFDQIKEELKKRNAVLVAHYYCDPDVQELAELTGGCVSDSLEM
ARFGRDHDATTLVVAGVKFMGETAKILSPEKTILMPTLEATCSLDLGCPVDEFSAFCDQHPDHTVVVYANTSAAVKARAD
WVVTSSCAVEIIEHLDSLGEKIIWAPDQHLGRYIQKKTGAEMLLWDGSCIVHEEFRARGIANMKALYPDAAVLVHPESPE
SVVEIADAVGSTSQLIKAAQTLPNERLIVATDRGIFYKMQQAVPHKILVEAPTAGEGATCRSCAHCPWMAMNELDGILHV
LQHADQEIHVDPQLAERAKLPLDRMLSFSASLKR

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 1 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=331, Percent_Identity=71.6012084592145, Blast_Score=501, Evalue=1e-143,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 38872; Mature: 38872

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDATLIANDAKVIVQAHLDRLGEPKDHHLSPDVKQAKFDQIKEELKKRNAVLVAHYYCD
CCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEECC
PDVQELAELTGGCVSDSLEMARFGRDHDATTLVVAGVKFMGETAKILSPEKTILMPTLEA
CCHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECHHHHCCHHHHCCCCCEEEEECCHH
TCSLDLGCPVDEFSAFCDQHPDHTVVVYANTSAAVKARADWVVTSSCAVEIIEHLDSLGE
HEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHHHHHHHCC
KIIWAPDQHLGRYIQKKTGAEMLLWDGSCIVHEEFRARGIANMKALYPDAAVLVHPESPE
EEEECCHHHHHHHHHHHCCCEEEEECCCEEEEHHHHHCCCCHHHHHCCCCEEEEECCCCH
SVVEIADAVGSTSQLIKAAQTLPNERLIVATDRGIFYKMQQAVPHKILVEAPTAGEGATC
HHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCEEEEECCCCCCCCCC
RSCAHCPWMAMNELDGILHVLQHADQEIHVDPQLAERAKLPLDRMLSFSASLKR
HHHCCCCCHHHHHHHHHHHHHHHCCCCEECCHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MNDATLIANDAKVIVQAHLDRLGEPKDHHLSPDVKQAKFDQIKEELKKRNAVLVAHYYCD
CCCCEEEECCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEECC
PDVQELAELTGGCVSDSLEMARFGRDHDATTLVVAGVKFMGETAKILSPEKTILMPTLEA
CCHHHHHHHCCCHHHHHHHHHHCCCCCCCCEEEEECHHHHCCHHHHCCCCCEEEEECCHH
TCSLDLGCPVDEFSAFCDQHPDHTVVVYANTSAAVKARADWVVTSSCAVEIIEHLDSLGE
HEEECCCCCHHHHHHHHHCCCCCEEEEEECCCCEEEECCCEEEEHHHHHHHHHHHHHHCC
KIIWAPDQHLGRYIQKKTGAEMLLWDGSCIVHEEFRARGIANMKALYPDAAVLVHPESPE
EEEECCHHHHHHHHHHHCCCEEEEECCCEEEEHHHHHCCCCHHHHHCCCCEEEEECCCCH
SVVEIADAVGSTSQLIKAAQTLPNERLIVATDRGIFYKMQQAVPHKILVEAPTAGEGATC
HHHHHHHHHCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHCCCCEEEEECCCCCCCCCC
RSCAHCPWMAMNELDGILHVLQHADQEIHVDPQLAERAKLPLDRMLSFSASLKR
HHHCCCCCHHHHHHHHHHHHHHHCCCCEECCHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA