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The map label for this gene is argJ

Identifier: 50083882

GI number: 50083882

Start: 640190

End: 641410

Strand: Direct

Name: argJ

Synonym: ACIAD0650

Alternate gene names: 50083882

Gene position: 640190-641410 (Clockwise)

Preceding gene: 50083881

Following gene: 50083883

Centisome position: 17.79

GC content: 43.49

Gene sequence:

>1221_bases
ATGGCTGTTGGTGACGTAACAATGCCGCACATGCATGTGGTAAATGGTGTAAAAATTGGTTCAACTGAAGCATATGTACG
TTATCCAAATCGACGAGATCTGGTTGTTTTTAAGTTTGTAGAAGGGTCTCATGTTGCGGGTGTCTTTACTCAAAGCGCAT
TTGCAGCCGCACCTGTGCTTGTATCAAAAAAACATTTAGCTGAAAGTGCGATCCGTTATCTGATTATCAATACGGGTAAT
GCGAATGCTGCTACAGGTCAAACAGGTGTAATCAATGCTCAAAAAACCTGTACTAAACTTGCCGAATTAGCTGGCGTAGA
ATCCAGTCAGGTATTGCCTTTTTCAACTGGTGTGATTGGTGAGCAACTCCCAATTGAGCGCTTACTTGATGGTATTCAGC
CAGCATTGCAAGATTTAAAAGATGATGCATGGACTGAAGCTGCCTTTGGTATCATGACGACAGATACCACACCAAAAGGT
GCATCAGAACAATTTGAGCTTGATGGTGTAGTTTATACCATGACAGGTATCAGTAAAGGCGCTGGCATGATTCGTCCAAA
TATGGCGACTATGCTTAGCTTCGTTGCTACTGATGCTCCAATCAGTCAATCACTGGTGCAAACGCTATTAAAGACAACAG
TTGAGCAATCATTTAACCGTATTACTATTGATGGTGATACCTCGACCAATGACTCTTGTATTTTTGTAGCGACAGGGCAA
GCAGGAGGGGTTGAAATCAGTTCTGAGCAAGATCCGAGATATTCCAAAATTCTTGAAATTTTGCAAAGAATTATGAATCG
TTTAGCACAGCTCATTGTTCGTGATGGTGAAGGTGCAACCAAATTCATTACCGTGGCTGTTGAGGGCGGAGAAAATACTC
AGGAATGCTGTGATGTTGCCTACAGTATTGCGCACTCTCCTCTGATTAAAACGGCTGTATTTGCATCCGATCCAAATTGG
GGGCGTATTGTGATGGCTATTGGTAAAGCAGGCGTACCGCAGTTAGATGTGAGTAAAGTTCAGGTCTGGCTAGATGACGT
ACAAATTTGCCGTGATGGTGGTGCTGCAGCGGATTACACCGAAGAACAGGGCGCTCGGGTGATGGCGCAGGCTGAAATGA
CGATTCGTGTAGATTTGGGACGTGGTACAGCAAAAGATACTGTATATACCTGTGATCTGTCGTATGATTATGTCAAGATT
AATGCGGACTATCGATCGTAA

Upstream 100 bases:

>100_bases
TTTGTAAATACAAGATAAATTTGCATAGATTAACGCTCGATTTTTCTGTTTATTTACACTAAGCTTTTCTTTTTGATAAC
AAACACAGTGGAAATCGAAA

Downstream 100 bases:

>100_bases
TTGATGACGATAAAAAACCTCATTCGTGAGGTTTTTTTTTAAATTTGGTTTTTTATCAGCTCATATTATCTTTACATGCT
GAGCTGTTGTACGTTAACGC

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MAVGDVTMPHMHVVNGVKIGSTEAYVRYPNRRDLVVFKFVEGSHVAGVFTQSAFAAAPVLVSKKHLAESAIRYLIINTGN
ANAATGQTGVINAQKTCTKLAELAGVESSQVLPFSTGVIGEQLPIERLLDGIQPALQDLKDDAWTEAAFGIMTTDTTPKG
ASEQFELDGVVYTMTGISKGAGMIRPNMATMLSFVATDAPISQSLVQTLLKTTVEQSFNRITIDGDTSTNDSCIFVATGQ
AGGVEISSEQDPRYSKILEILQRIMNRLAQLIVRDGEGATKFITVAVEGGENTQECCDVAYSIAHSPLIKTAVFASDPNW
GRIVMAIGKAGVPQLDVSKVQVWLDDVQICRDGGAAADYTEEQGARVMAQAEMTIRVDLGRGTAKDTVYTCDLSYDYVKI
NADYRS

Sequences:

>Translated_406_residues
MAVGDVTMPHMHVVNGVKIGSTEAYVRYPNRRDLVVFKFVEGSHVAGVFTQSAFAAAPVLVSKKHLAESAIRYLIINTGN
ANAATGQTGVINAQKTCTKLAELAGVESSQVLPFSTGVIGEQLPIERLLDGIQPALQDLKDDAWTEAAFGIMTTDTTPKG
ASEQFELDGVVYTMTGISKGAGMIRPNMATMLSFVATDAPISQSLVQTLLKTTVEQSFNRITIDGDTSTNDSCIFVATGQ
AGGVEISSEQDPRYSKILEILQRIMNRLAQLIVRDGEGATKFITVAVEGGENTQECCDVAYSIAHSPLIKTAVFASDPNW
GRIVMAIGKAGVPQLDVSKVQVWLDDVQICRDGGAAADYTEEQGARVMAQAEMTIRVDLGRGTAKDTVYTCDLSYDYVKI
NADYRS
>Mature_405_residues
AVGDVTMPHMHVVNGVKIGSTEAYVRYPNRRDLVVFKFVEGSHVAGVFTQSAFAAAPVLVSKKHLAESAIRYLIINTGNA
NAATGQTGVINAQKTCTKLAELAGVESSQVLPFSTGVIGEQLPIERLLDGIQPALQDLKDDAWTEAAFGIMTTDTTPKGA
SEQFELDGVVYTMTGISKGAGMIRPNMATMLSFVATDAPISQSLVQTLLKTTVEQSFNRITIDGDTSTNDSCIFVATGQA
GGVEISSEQDPRYSKILEILQRIMNRLAQLIVRDGEGATKFITVAVEGGENTQECCDVAYSIAHSPLIKTAVFASDPNWG
RIVMAIGKAGVPQLDVSKVQVWLDDVQICRDGGAAADYTEEQGARVMAQAEMTIRVDLGRGTAKDTVYTCDLSYDYVKIN
ADYRS

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=414, Percent_Identity=38.4057971014493, Blast_Score=254, Evalue=3e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ARGJ_ACIAD (Q6FED8)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045392.1
- ProteinModelPortal:   Q6FED8
- SMR:   Q6FED8
- STRING:   Q6FED8
- MEROPS:   T05.001
- GeneID:   2877981
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0650
- NMPDR:   fig|62977.3.peg.295
- eggNOG:   COG1364
- HOGENOM:   HBG284202
- OMA:   QNRFCAA
- PhylomeDB:   Q6FED8
- ProtClustDB:   PRK05388
- BioCyc:   ASP62977:ACIAD0650-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01106
- InterPro:   IPR002813
- InterPro:   IPR016117
- PANTHER:   PTHR23100
- TIGRFAMs:   TIGR00120

Pfam domain/function: PF01960 ArgJ; SSF56266 Pept_S58_DmpA/Arg_biosyn_ArgJ

EC number: =2.3.1.35; =2.3.1.1

Molecular weight: Translated: 43579; Mature: 43448

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVGDVTMPHMHVVNGVKIGSTEAYVRYPNRRDLVVFKFVEGSHVAGVFTQSAFAAAPVL
CCCCCCCCCCCHHCCCEEECCCCEEEECCCCCCEEEEEEECCCEEEEEHHHHHHHHCCHH
VSKKHLAESAIRYLIINTGNANAATGQTGVINAQKTCTKLAELAGVESSQVLPFSTGVIG
HHHHHHHHCEEEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCEEECCCCC
EQLPIERLLDGIQPALQDLKDDAWTEAAFGIMTTDTTPKGASEQFELDGVVYTMTGISKG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCEEECCEEEEEECCCCC
AGMIRPNMATMLSFVATDAPISQSLVQTLLKTTVEQSFNRITIDGDTSTNDSCIFVATGQ
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEECC
AGGVEISSEQDPRYSKILEILQRIMNRLAQLIVRDGEGATKFITVAVEGGENTQECCDVA
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEECCCCHHHHHHHH
YSIAHSPLIKTAVFASDPNWGRIVMAIGKAGVPQLDVSKVQVWLDDVQICRDGGAAADYT
HHHHCCCHHHEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
EEQGARVMAQAEMTIRVDLGRGTAKDTVYTCDLSYDYVKINADYRS
HHCCCEEEEEEEEEEEEEECCCCCCCEEEEEECCEEEEEEECCCCC
>Mature Secondary Structure 
AVGDVTMPHMHVVNGVKIGSTEAYVRYPNRRDLVVFKFVEGSHVAGVFTQSAFAAAPVL
CCCCCCCCCCHHCCCEEECCCCEEEECCCCCCEEEEEEECCCEEEEEHHHHHHHHCCHH
VSKKHLAESAIRYLIINTGNANAATGQTGVINAQKTCTKLAELAGVESSQVLPFSTGVIG
HHHHHHHHCEEEEEEEECCCCCCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCEEECCCCC
EQLPIERLLDGIQPALQDLKDDAWTEAAFGIMTTDTTPKGASEQFELDGVVYTMTGISKG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCCCCCEEECCEEEEEECCCCC
AGMIRPNMATMLSFVATDAPISQSLVQTLLKTTVEQSFNRITIDGDTSTNDSCIFVATGQ
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCEEEEEECC
AGGVEISSEQDPRYSKILEILQRIMNRLAQLIVRDGEGATKFITVAVEGGENTQECCDVA
CCCEEECCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEECCCCHHHHHHHH
YSIAHSPLIKTAVFASDPNWGRIVMAIGKAGVPQLDVSKVQVWLDDVQICRDGGAAADYT
HHHHCCCHHHEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCC
EEQGARVMAQAEMTIRVDLGRGTAKDTVYTCDLSYDYVKINADYRS
HHCCCEEEEEEEEEEEEEECCCCCCCEEEEEECCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA