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The map label for this gene is ahpC [C]

Identifier: 50083879

GI number: 50083879

Start: 635833

End: 636489

Strand: Reverse

Name: ahpC [C]

Synonym: ACIAD0647

Alternate gene names: 50083879

Gene position: 636489-635833 (Counterclockwise)

Preceding gene: 50083884

Following gene: 50083878

Centisome position: 17.69

GC content: 41.4

Gene sequence:

>657_bases
ATGAGGTTTTGCACCATGACTTTACGTTTAGGCGATACAGCGCCCAATTTTGAACAAGATTCTAGCGAAGGTCTAATTAA
TTTTTATGACTTTTTGGGTGATAGTTGGGGCATCCTGTTTTCGCATCCAGCAGATTATACGCCTGTATGTACTACAGAAT
TAGGATATACCGCAAAACTCAAAGATGAATTTGAAAAACGTCATGTCAAAGCCATTGCTCTTTCGGTAGATGATGTCGAT
TCACATCAGGGCTGGATTAAAGACATCAATGAAACCCAACAGACCACGGTTAACTTTCCAATTTTGGCCGATAAAGACCG
TCAGGTTTCTGAGCTTTATGGTTTTATTCATCCGAATGCAAGTGAAACCACCACTGTTCGTTCATTGGTCATTATCGATC
CGAATAAAAAAGTGAGACTTATTATTACCTATCCAGCTTCGACTGGACGAAATTTCAATGAAGTATTGCGTGTCATCGAC
TCTTTACAATTGACAGACAACTACAAGGTCGCAACCCCTGCCAACTGGCAGCAAGGTGAAGATGTAGTGATTGTACCGTC
AATTAAGGATGAAGCTGAACTTAAAGAACGCTTTCCCAAAGGCTACAAGGCCGTTACCCCGTACCTACGCTTAACACCAC
AGCCTGATCAGAAATAA

Upstream 100 bases:

>100_bases
TTTCTATATACAAAAAATTCATAATAAAATACAAAAACCTTTATTTTATTTGCAATATAAATGTCGCATATTAGATCTCA
TTAGATAGAACAATATACAG

Downstream 100 bases:

>100_bases
AATAATAAGACGAATAACAGCAAGCCTATCCATCTGATAGGCTTTTTCCTTTTTATAAGTGCTTTAATTTACATTGGACT
TCTCAGGTATTTCAGTGATA

Product: antioxidant protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MRFCTMTLRLGDTAPNFEQDSSEGLINFYDFLGDSWGILFSHPADYTPVCTTELGYTAKLKDEFEKRHVKAIALSVDDVD
SHQGWIKDINETQQTTVNFPILADKDRQVSELYGFIHPNASETTTVRSLVIIDPNKKVRLIITYPASTGRNFNEVLRVID
SLQLTDNYKVATPANWQQGEDVVIVPSIKDEAELKERFPKGYKAVTPYLRLTPQPDQK

Sequences:

>Translated_218_residues
MRFCTMTLRLGDTAPNFEQDSSEGLINFYDFLGDSWGILFSHPADYTPVCTTELGYTAKLKDEFEKRHVKAIALSVDDVD
SHQGWIKDINETQQTTVNFPILADKDRQVSELYGFIHPNASETTTVRSLVIIDPNKKVRLIITYPASTGRNFNEVLRVID
SLQLTDNYKVATPANWQQGEDVVIVPSIKDEAELKERFPKGYKAVTPYLRLTPQPDQK
>Mature_218_residues
MRFCTMTLRLGDTAPNFEQDSSEGLINFYDFLGDSWGILFSHPADYTPVCTTELGYTAKLKDEFEKRHVKAIALSVDDVD
SHQGWIKDINETQQTTVNFPILADKDRQVSELYGFIHPNASETTTVRSLVIIDPNKKVRLIITYPASTGRNFNEVLRVID
SLQLTDNYKVATPANWQQGEDVVIVPSIKDEAELKERFPKGYKAVTPYLRLTPQPDQK

Specific function: Directly Reduces Organic Hydroperoxides In Its Reduced Dithiol Form. [C]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4758638, Length=221, Percent_Identity=51.131221719457, Blast_Score=221, Evalue=4e-58,
Organism=Homo sapiens, GI32189392, Length=190, Percent_Identity=32.1052631578947, Blast_Score=95, Evalue=4e-20,
Organism=Homo sapiens, GI4505591, Length=191, Percent_Identity=29.8429319371728, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI32455266, Length=191, Percent_Identity=29.8429319371728, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI32455264, Length=191, Percent_Identity=29.8429319371728, Blast_Score=91, Evalue=9e-19,
Organism=Homo sapiens, GI5453549, Length=148, Percent_Identity=30.4054054054054, Blast_Score=79, Evalue=2e-15,
Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=31.2138728323699, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=31.2138728323699, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1786822, Length=154, Percent_Identity=27.2727272727273, Blast_Score=66, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI25153706, Length=200, Percent_Identity=42, Blast_Score=168, Evalue=2e-42,
Organism=Caenorhabditis elegans, GI193204376, Length=189, Percent_Identity=31.7460317460317, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI32565831, Length=189, Percent_Identity=31.7460317460317, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17554494, Length=195, Percent_Identity=28.2051282051282, Blast_Score=81, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6319407, Length=212, Percent_Identity=55.188679245283, Blast_Score=233, Evalue=2e-62,
Organism=Saccharomyces cerevisiae, GI6320661, Length=157, Percent_Identity=31.8471337579618, Blast_Score=74, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6323613, Length=160, Percent_Identity=30.625, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24581278, Length=219, Percent_Identity=48.4018264840183, Blast_Score=213, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24652434, Length=207, Percent_Identity=48.3091787439614, Blast_Score=190, Evalue=6e-49,
Organism=Drosophila melanogaster, GI24652436, Length=207, Percent_Identity=48.3091787439614, Blast_Score=189, Evalue=8e-49,
Organism=Drosophila melanogaster, GI17975518, Length=207, Percent_Identity=48.3091787439614, Blast_Score=189, Evalue=9e-49,
Organism=Drosophila melanogaster, GI17157991, Length=174, Percent_Identity=31.0344827586207, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24641739, Length=174, Percent_Identity=31.0344827586207, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21357347, Length=198, Percent_Identity=28.7878787878788, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24656348, Length=160, Percent_Identity=29.375, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17864676, Length=160, Percent_Identity=29.375, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI17738015, Length=175, Percent_Identity=29.1428571428571, Blast_Score=76, Evalue=2e-14,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR019479
- InterPro:   IPR022915
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 24759; Mature: 24759

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFCTMTLRLGDTAPNFEQDSSEGLINFYDFLGDSWGILFSHPADYTPVCTTELGYTAKL
CCEEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCEEECCCCCEEHH
KDEFEKRHVKAIALSVDDVDSHQGWIKDINETQQTTVNFPILADKDRQVSELYGFIHPNA
HHHHHHHEEEEEEEEECCCCCCCCHHHHCCCHHHEEECCCEEECCCCCHHHHHEEECCCC
SETTTVRSLVIIDPNKKVRLIITYPASTGRNFNEVLRVIDSLQLTDNYKVATPANWQQGE
CCCEEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHEECCCCEEEECCCCCCCCC
DVVIVPSIKDEAELKERFPKGYKAVTPYLRLTPQPDQK
CEEEEECCCCHHHHHHHCCCCCEECCCEEEECCCCCCC
>Mature Secondary Structure
MRFCTMTLRLGDTAPNFEQDSSEGLINFYDFLGDSWGILFSHPADYTPVCTTELGYTAKL
CCEEEEEEEECCCCCCCCCCCCCCHHHHHHHCCCCCCEEEECCCCCCCEEECCCCCEEHH
KDEFEKRHVKAIALSVDDVDSHQGWIKDINETQQTTVNFPILADKDRQVSELYGFIHPNA
HHHHHHHEEEEEEEEECCCCCCCCHHHHCCCHHHEEECCCEEECCCCCHHHHHEEECCCC
SETTTVRSLVIIDPNKKVRLIITYPASTGRNFNEVLRVIDSLQLTDNYKVATPANWQQGE
CCCEEEEEEEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHEECCCCEEEECCCCCCCCC
DVVIVPSIKDEAELKERFPKGYKAVTPYLRLTPQPDQK
CEEEEECCCCHHHHHHHCCCCCEECCCEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824 [H]