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The map label for this gene is acdA [H]

Identifier: 50083856

GI number: 50083856

Start: 609925

End: 611715

Strand: Reverse

Name: acdA [H]

Synonym: ACIAD0623

Alternate gene names: 50083856

Gene position: 611715-609925 (Counterclockwise)

Preceding gene: 50083857

Following gene: 50083854

Centisome position: 17.0

GC content: 43.33

Gene sequence:

>1791_bases
GTGAACACCATGCCAATTTATAATGCTCCCCTTGCAGATATGCGTTTTATCCTAAACGATGTATTTAATGCAGAACAATT
CTGGCAAGCCAATGAAAATCTTGCACATATTGATGCCGCGACAGCAGAAGCCATTTTAGAAGAAATGGCCAAATTTGCGC
AAAATGTTACTTCACCCTTGAACCGTACAGGCGATGAAGAAGGCGCACATTATGATCAAGGTCAGGTCACCACACCTGCG
GGTTTTAAAGATGCTTTTCAGCAATATGCACAAGGCGGCTGGATTGGTTTAGGTGCGGATGAAGAATGGGGCGGCCAAGG
TATGCCAAAAATGCTCACCGTTCTTGCTGACGAAATGTTATTTGCCACCAATCCATCATTTATGCTCTATCCTCTGCTTT
CTGTCGGTGCAGGTATGGCATTGAATAGTTATGCCTCTCAAGAGCAAAAAGAAACCTATTTGCCAAAAATATATTCGGGC
GAATGGTCTGGAACGATGTGTTTAACTGAGCCACATGCAGGGACAGATTTAGGTATTATCAAAACCAAAGCTGAACCAAA
TGTTGATGGTAGCTACCATATTACAGGAACCAAGATCTTTATTACTGGTGGAGATCATGACCTCAGTCAGAACATCATCC
ATCTTGTATTAGCCAAAACCCCAGATGCACCTGCAGGATCACGTGGCATTTCGCTGTTTATTGTGCCTAAATTTTTAGTC
AATGAAGATGGTTCGCTGGGTGAACGCAACGCAGTTGGTCCTGGTTCGATTGAACATAAAATGGGGATCAAAGCATCGGC
TACTTGTGTCATGAACTTCGATGGTGCCAAAGGCTTTTTGGTCGGTAAGGAAAACGAAGGGCTGGCTGCCATGTTTGTCA
TGATGAACTACGAACGTTTATCCATGGGTATTCAAGGTCTAGGTGCTTCTGAGTTTGCCTATCAAAATGCAGCACAGTAT
GCGACAGACCGTTTACAGGGTCGTAGTGCATCGGGTGTTCAGTCACCAAATAAACCTGCCGATAGCATCTTGGTCCATGG
TGATGTGCGTCGTATGTTGCTCAATGTCAGAGCAAATAATGAAGCTTCACGTGCCTTTGCAGTTTATGTGGGCCAACAAC
TCGACATTACCAAGTTTTCAACTGACCCAGAGGCGGTAAAAAAAGCCAATAACCGTGTAGCTTTGCTGACACCTATTGCC
AAAGCCTATCTGACTGACACAGCCTTTCAGGCGACATTAGATGCACAAATGTGCTTTGGTGGGCATGGCTATATTCGTGA
ATGGGGGATGGAGCAATGTGTTCGTGACTTACGTATTGCCCAGATTTACGAAGGTACCAATGGCGTTCAGTCTCAAGACT
TAATTGGTCGTAAAACCATTAAATGTGGTGGCGCATTTATTGCTGAATATATCAGCGAAATTCGTGATTTTACCAATACT
TTGGGTGCCGATCTCAACTTTATCAAAGATGCCACACTGGATGCCGCCACAGAAGTTGAAGCGATTACTCAATTCATTAT
TGAACAAGCTGCTGAAAGTGCGGAGTTTCCAAATGCTGCCGCAGTAGATTATTTGCATGCAGTTGGTTTACTCAGTTTTG
CCTATATGTTTGCTAAAATCTCAGCCGCCGCTAAAGAAAAATCAGGCGAGTTCTATCAAAATAAACTGGCACTTGCACAA
TATTTTGTAGGTCGTATTTTGCCAGAACTGGAATCACGTATTAAGAAAATTGAGGCGGGTTCAGATTTAGTAATGAGTTT
TACTGAAGACTACTTTACGACTCAATCCTAA

Upstream 100 bases:

>100_bases
CTTTTTTTATAAAATCGGTGATAAATTAAAGCTATTCCAGAAACCGTCATTGCTTATATTTATTGTGTAATATGAAGCAC
ATAAATGTAAAATAACAAAG

Downstream 100 bases:

>100_bases
TTTACCGCAAATAAAAAAATGCCTGCTTATGCAGGCGTTTTTTATTTAGGATAAAACTTATGAATTGAATTTGCTATTTG
CGGCTCAAGCTCGTTCAATG

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 596; Mature: 596

Protein sequence:

>596_residues
MNTMPIYNAPLADMRFILNDVFNAEQFWQANENLAHIDAATAEAILEEMAKFAQNVTSPLNRTGDEEGAHYDQGQVTTPA
GFKDAFQQYAQGGWIGLGADEEWGGQGMPKMLTVLADEMLFATNPSFMLYPLLSVGAGMALNSYASQEQKETYLPKIYSG
EWSGTMCLTEPHAGTDLGIIKTKAEPNVDGSYHITGTKIFITGGDHDLSQNIIHLVLAKTPDAPAGSRGISLFIVPKFLV
NEDGSLGERNAVGPGSIEHKMGIKASATCVMNFDGAKGFLVGKENEGLAAMFVMMNYERLSMGIQGLGASEFAYQNAAQY
ATDRLQGRSASGVQSPNKPADSILVHGDVRRMLLNVRANNEASRAFAVYVGQQLDITKFSTDPEAVKKANNRVALLTPIA
KAYLTDTAFQATLDAQMCFGGHGYIREWGMEQCVRDLRIAQIYEGTNGVQSQDLIGRKTIKCGGAFIAEYISEIRDFTNT
LGADLNFIKDATLDAATEVEAITQFIIEQAAESAEFPNAAAVDYLHAVGLLSFAYMFAKISAAAKEKSGEFYQNKLALAQ
YFVGRILPELESRIKKIEAGSDLVMSFTEDYFTTQS

Sequences:

>Translated_596_residues
MNTMPIYNAPLADMRFILNDVFNAEQFWQANENLAHIDAATAEAILEEMAKFAQNVTSPLNRTGDEEGAHYDQGQVTTPA
GFKDAFQQYAQGGWIGLGADEEWGGQGMPKMLTVLADEMLFATNPSFMLYPLLSVGAGMALNSYASQEQKETYLPKIYSG
EWSGTMCLTEPHAGTDLGIIKTKAEPNVDGSYHITGTKIFITGGDHDLSQNIIHLVLAKTPDAPAGSRGISLFIVPKFLV
NEDGSLGERNAVGPGSIEHKMGIKASATCVMNFDGAKGFLVGKENEGLAAMFVMMNYERLSMGIQGLGASEFAYQNAAQY
ATDRLQGRSASGVQSPNKPADSILVHGDVRRMLLNVRANNEASRAFAVYVGQQLDITKFSTDPEAVKKANNRVALLTPIA
KAYLTDTAFQATLDAQMCFGGHGYIREWGMEQCVRDLRIAQIYEGTNGVQSQDLIGRKTIKCGGAFIAEYISEIRDFTNT
LGADLNFIKDATLDAATEVEAITQFIIEQAAESAEFPNAAAVDYLHAVGLLSFAYMFAKISAAAKEKSGEFYQNKLALAQ
YFVGRILPELESRIKKIEAGSDLVMSFTEDYFTTQS
>Mature_596_residues
MNTMPIYNAPLADMRFILNDVFNAEQFWQANENLAHIDAATAEAILEEMAKFAQNVTSPLNRTGDEEGAHYDQGQVTTPA
GFKDAFQQYAQGGWIGLGADEEWGGQGMPKMLTVLADEMLFATNPSFMLYPLLSVGAGMALNSYASQEQKETYLPKIYSG
EWSGTMCLTEPHAGTDLGIIKTKAEPNVDGSYHITGTKIFITGGDHDLSQNIIHLVLAKTPDAPAGSRGISLFIVPKFLV
NEDGSLGERNAVGPGSIEHKMGIKASATCVMNFDGAKGFLVGKENEGLAAMFVMMNYERLSMGIQGLGASEFAYQNAAQY
ATDRLQGRSASGVQSPNKPADSILVHGDVRRMLLNVRANNEASRAFAVYVGQQLDITKFSTDPEAVKKANNRVALLTPIA
KAYLTDTAFQATLDAQMCFGGHGYIREWGMEQCVRDLRIAQIYEGTNGVQSQDLIGRKTIKCGGAFIAEYISEIRDFTNT
LGADLNFIKDATLDAATEVEAITQFIIEQAAESAEFPNAAAVDYLHAVGLLSFAYMFAKISAAAKEKSGEFYQNKLALAQ
YFVGRILPELESRIKKIEAGSDLVMSFTEDYFTTQS

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=411, Percent_Identity=26.2773722627737, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI4557235, Length=425, Percent_Identity=27.5294117647059, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI76496475, Length=425, Percent_Identity=27.5294117647059, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI226958412, Length=418, Percent_Identity=28.4688995215311, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI4501857, Length=386, Percent_Identity=26.9430051813472, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI226958414, Length=382, Percent_Identity=29.3193717277487, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI21361497, Length=372, Percent_Identity=27.4193548387097, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI7656849, Length=386, Percent_Identity=25.3886010362694, Blast_Score=93, Evalue=9e-19,
Organism=Homo sapiens, GI4557233, Length=432, Percent_Identity=26.3888888888889, Blast_Score=87, Evalue=5e-17,
Organism=Homo sapiens, GI187960098, Length=313, Percent_Identity=28.1150159744409, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI4557231, Length=313, Percent_Identity=28.1150159744409, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI4503943, Length=321, Percent_Identity=28.6604361370716, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI7669494, Length=190, Percent_Identity=32.6315789473684, Blast_Score=79, Evalue=2e-14,
Organism=Escherichia coli, GI87082384, Length=290, Percent_Identity=27.5862068965517, Blast_Score=89, Evalue=7e-19,
Organism=Caenorhabditis elegans, GI17508101, Length=411, Percent_Identity=27.007299270073, Blast_Score=111, Evalue=9e-25,
Organism=Caenorhabditis elegans, GI17569725, Length=365, Percent_Identity=29.041095890411, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI17533517, Length=423, Percent_Identity=25.7683215130024, Blast_Score=104, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71985184, Length=378, Percent_Identity=27.5132275132275, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=427, Percent_Identity=27.8688524590164, Blast_Score=102, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI17534899, Length=363, Percent_Identity=28.099173553719, Blast_Score=102, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17506239, Length=405, Percent_Identity=25.679012345679, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI86563383, Length=357, Percent_Identity=26.0504201680672, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI86563381, Length=357, Percent_Identity=26.0504201680672, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17570075, Length=320, Percent_Identity=26.25, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI32563615, Length=237, Percent_Identity=28.2700421940928, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71990804, Length=267, Percent_Identity=27.3408239700375, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71985192, Length=253, Percent_Identity=30.4347826086957, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17505929, Length=372, Percent_Identity=23.9247311827957, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI281363737, Length=364, Percent_Identity=28.2967032967033, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24666513, Length=413, Percent_Identity=27.3607748184019, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21355753, Length=389, Percent_Identity=27.5064267352185, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24660351, Length=316, Percent_Identity=29.746835443038, Blast_Score=92, Evalue=9e-19,
Organism=Drosophila melanogaster, GI21356377, Length=405, Percent_Identity=27.1604938271605, Blast_Score=89, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24646207, Length=392, Percent_Identity=23.7244897959184, Blast_Score=69, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 64821; Mature: 64821

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTMPIYNAPLADMRFILNDVFNAEQFWQANENLAHIDAATAEAILEEMAKFAQNVTSPL
CCCCCCCCCCHHHHHHHHHHHHCHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
NRTGDEEGAHYDQGQVTTPAGFKDAFQQYAQGGWIGLGADEEWGGQGMPKMLTVLADEML
HCCCCCCCCCCCCCCEECCCCHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHH
FATNPSFMLYPLLSVGAGMALNSYASQEQKETYLPKIYSGEWSGTMCLTEPHAGTDLGII
EECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCCCEEE
KTKAEPNVDGSYHITGTKIFITGGDHDLSQNIIHLVLAKTPDAPAGSRGISLFIVPKFLV
EECCCCCCCCEEEEEEEEEEEECCCCCHHHHHEEEEEECCCCCCCCCCCEEEEEEEHHEE
NEDGSLGERNAVGPGSIEHKMGIKASATCVMNFDGAKGFLVGKENEGLAAMFVMMNYERL
CCCCCCCCCCCCCCCCCHHHCCCCEEEEEEEEECCCCEEEEECCCCCCEEEHHHHHHHHH
SMGIQGLGASEFAYQNAAQYATDRLQGRSASGVQSPNKPADSILVHGDVRRMLLNVRANN
HHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCC
EASRAFAVYVGQQLDITKFSTDPEAVKKANNRVALLTPIAKAYLTDTAFQATLDAQMCFG
CCCCEEEEEECCEEEEEECCCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHEEC
GHGYIREWGMEQCVRDLRIAQIYEGTNGVQSQDLIGRKTIKCGGAFIAEYISEIRDFTNT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LGADLNFIKDATLDAATEVEAITQFIIEQAAESAEFPNAAAVDYLHAVGLLSFAYMFAKI
HCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
SAAAKEKSGEFYQNKLALAQYFVGRILPELESRIKKIEAGSDLVMSFTEDYFTTQS
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTMPIYNAPLADMRFILNDVFNAEQFWQANENLAHIDAATAEAILEEMAKFAQNVTSPL
CCCCCCCCCCHHHHHHHHHHHHCHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHH
NRTGDEEGAHYDQGQVTTPAGFKDAFQQYAQGGWIGLGADEEWGGQGMPKMLTVLADEML
HCCCCCCCCCCCCCCEECCCCHHHHHHHHHCCCEEECCCCCCCCCCCHHHHHHHHHHHHH
FATNPSFMLYPLLSVGAGMALNSYASQEQKETYLPKIYSGEWSGTMCLTEPHAGTDLGII
EECCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCCCCEEEEECCCCCCCCEEE
KTKAEPNVDGSYHITGTKIFITGGDHDLSQNIIHLVLAKTPDAPAGSRGISLFIVPKFLV
EECCCCCCCCEEEEEEEEEEEECCCCCHHHHHEEEEEECCCCCCCCCCCEEEEEEEHHEE
NEDGSLGERNAVGPGSIEHKMGIKASATCVMNFDGAKGFLVGKENEGLAAMFVMMNYERL
CCCCCCCCCCCCCCCCCHHHCCCCEEEEEEEEECCCCEEEEECCCCCCEEEHHHHHHHHH
SMGIQGLGASEFAYQNAAQYATDRLQGRSASGVQSPNKPADSILVHGDVRRMLLNVRANN
HHCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHCCCC
EASRAFAVYVGQQLDITKFSTDPEAVKKANNRVALLTPIAKAYLTDTAFQATLDAQMCFG
CCCCEEEEEECCEEEEEECCCCHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHHHHHEEC
GHGYIREWGMEQCVRDLRIAQIYEGTNGVQSQDLIGRKTIKCGGAFIAEYISEIRDFTNT
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHH
LGADLNFIKDATLDAATEVEAITQFIIEQAAESAEFPNAAAVDYLHAVGLLSFAYMFAKI
HCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
SAAAKEKSGEFYQNKLALAQYFVGRILPELESRIKKIEAGSDLVMSFTEDYFTTQS
HHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]