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The map label for this gene is acdB [H]

Identifier: 50083857

GI number: 50083857

Start: 611878

End: 613755

Strand: Reverse

Name: acdB [H]

Synonym: ACIAD0624

Alternate gene names: 50083857

Gene position: 613755-611878 (Counterclockwise)

Preceding gene: 50083858

Following gene: 50083856

Centisome position: 17.06

GC content: 43.08

Gene sequence:

>1878_bases
GTGTCTGCTGGGCACCCCCATCGTTACAGTCAGGATATTATAAACGCTGGTTTAACCAGTATTGAGGAAACCGATATGCC
ACAATACAAAGCGCCTTTACGTGATATGCAATTTGTTTTGCATGAGTTATTAAATGCCAATGAACATTATGCAAAACTTC
CCGCATTCCAAGAAAACGTAAGCCGTGAACTGGTCGATCAATATTTGGAAGCTGCCGCAGATTTCTGTGAAAACGAGTTG
TCTCCACTCAATCAAGTCGGTGACCGTGAAGGCTGTACATGGAATGATGGTGTTGTCACGACTCCAACAGGTTTTAAAGA
AGCCTATCAGAAGTATATCGAACTCGGTTTCCCTTCACTTTCTGCCGAAGAACAATATGGCGGGCAAGGATTACCAAACT
CTCTTGGAATTGCCATTTCAGAAATGGTCGGTTCATCAAACTGGGCTTGGGGTATGTATCCTGGTCTTTCACATGGTGCT
GTACGTACCTTAGAACATCATGGTTCAGAGCAACAAAAAGATACTTATCTGCCTAATCTTGTTTCAGGCGTATGGACAGG
AACCATGTGCTTAACTGAATCTCATGCAGGTTCAGACTTGGGAATTATTCGTTCGAAAGCGGAACCGAATGAAGATGGCA
GCTATGCAATCTCAGGCGAGAAAATCTTTATCTCGGCTGGTGAACACGACATGGCTGACAATATTATTCATATTGTACTT
GCACGTTTGCCAGGTGCCCCAAAAGGTACCAAAGGTATTTCTTTATTCATCGTACCAAAATTTCTGGTCAATGAAGATGG
TTCATTAGGTGAACGTAATCACGTGCGCTGTGGTTCTATTGAACACAAAATGGGCATTCATGGTAATGCAACCTGCGTGA
TTAATTTTGATCGTGCTAAAGGTTACTTGATTGGGCCTGAAAACCGTGGTCTGAACTGTATGTTTACCTTCATGAATACT
GCACGTATTGGTACAGCAGTACAAGGTTTGGCAGCTTCTGAATCATCATTCCAAGGCGCTTTGACTTATGCCAAAGATCG
TCTGGCGATGCGCTCACTCTCTGGTCCAAAAGCTCCAGAAAAAGATGCAGATCCAATTATTGTTCATCCAGCTGTACGCA
ACATGCTTTTAACACAGAAGGCTTTTGCTGAAGGTGGCCGTGCATTGGTATATTTACTGGCACAATATGCAGATGTGGTT
GAGCATGGTATTACCGAAGAAGAACGGAAATTTGCAGATAATATCCTGTCTTTACTCACCCCAATTGCCAAAGCATTTTT
GACTGAAACTGGTTCAGAATCTGCTAAACATGGCGTACAGGTATTCGGTGGTCATGGCTTTATTTCTGAGCATGGTATGG
AACAAATTGTTCGTGATACCCGTATTGCTTGCTTGTATGAAGGCACGACAGAAATTCAGGCTCTGGATTTATTAGGTCGT
AAGGTTCTACAAACTCAAGGTGCAATGTTACGTGACTTCACGAAAATCATTCACAAGTTTGTCGAAGCCAACAAAGACAA
CGCTGCAATGAAAGAGTTTATTGAACCACTTGCTTCACTAAATAAAGAGTGGGGTGATGTCACCATGCAAATTGGTATGC
GTGCCATGCAAAATCCAGATGAAGTGGGTGCAGCAGCAGTAGATTATCTCTATTTCTCTGGTTATGTCACACTGGCTTAC
TTGTGGGCACGTATGGCAGAAGTAGCGCAACAGAAACTTGCTGCTGGAACCACAGATGCAGATTTCTACAATGCCAAAGT
GACCACTGCTCGCTTCTACTTTAAGAAAATTCTGCCACGTGTTCGCTCTCATGTAGATGTACTTTCAACGGGTGTAGAAT
CCTTGATGGCACTTGATGCAGAACACTTTGCGTTCTAA

Upstream 100 bases:

>100_bases
CATTTTAAGATAATTTTCTTTGACTTTACAGTCATGGATTAACACCCCGAAAAGCTTGTAGACACGTATAAGTTATTGCA
CGATGTAAAGCATAACAAAG

Downstream 100 bases:

>100_bases
TCATACTGAAGCGTTGATTGCAACGTGATAGTCAGAGAAAGGACTGATCAGTTTTGACAGTCCTTTTTTTATAAAATCGG
TGATAAATTAAAGCTATTCC

Product: acyl-CoA dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 625; Mature: 624

Protein sequence:

>625_residues
MSAGHPHRYSQDIINAGLTSIEETDMPQYKAPLRDMQFVLHELLNANEHYAKLPAFQENVSRELVDQYLEAAADFCENEL
SPLNQVGDREGCTWNDGVVTTPTGFKEAYQKYIELGFPSLSAEEQYGGQGLPNSLGIAISEMVGSSNWAWGMYPGLSHGA
VRTLEHHGSEQQKDTYLPNLVSGVWTGTMCLTESHAGSDLGIIRSKAEPNEDGSYAISGEKIFISAGEHDMADNIIHIVL
ARLPGAPKGTKGISLFIVPKFLVNEDGSLGERNHVRCGSIEHKMGIHGNATCVINFDRAKGYLIGPENRGLNCMFTFMNT
ARIGTAVQGLAASESSFQGALTYAKDRLAMRSLSGPKAPEKDADPIIVHPAVRNMLLTQKAFAEGGRALVYLLAQYADVV
EHGITEEERKFADNILSLLTPIAKAFLTETGSESAKHGVQVFGGHGFISEHGMEQIVRDTRIACLYEGTTEIQALDLLGR
KVLQTQGAMLRDFTKIIHKFVEANKDNAAMKEFIEPLASLNKEWGDVTMQIGMRAMQNPDEVGAAAVDYLYFSGYVTLAY
LWARMAEVAQQKLAAGTTDADFYNAKVTTARFYFKKILPRVRSHVDVLSTGVESLMALDAEHFAF

Sequences:

>Translated_625_residues
MSAGHPHRYSQDIINAGLTSIEETDMPQYKAPLRDMQFVLHELLNANEHYAKLPAFQENVSRELVDQYLEAAADFCENEL
SPLNQVGDREGCTWNDGVVTTPTGFKEAYQKYIELGFPSLSAEEQYGGQGLPNSLGIAISEMVGSSNWAWGMYPGLSHGA
VRTLEHHGSEQQKDTYLPNLVSGVWTGTMCLTESHAGSDLGIIRSKAEPNEDGSYAISGEKIFISAGEHDMADNIIHIVL
ARLPGAPKGTKGISLFIVPKFLVNEDGSLGERNHVRCGSIEHKMGIHGNATCVINFDRAKGYLIGPENRGLNCMFTFMNT
ARIGTAVQGLAASESSFQGALTYAKDRLAMRSLSGPKAPEKDADPIIVHPAVRNMLLTQKAFAEGGRALVYLLAQYADVV
EHGITEEERKFADNILSLLTPIAKAFLTETGSESAKHGVQVFGGHGFISEHGMEQIVRDTRIACLYEGTTEIQALDLLGR
KVLQTQGAMLRDFTKIIHKFVEANKDNAAMKEFIEPLASLNKEWGDVTMQIGMRAMQNPDEVGAAAVDYLYFSGYVTLAY
LWARMAEVAQQKLAAGTTDADFYNAKVTTARFYFKKILPRVRSHVDVLSTGVESLMALDAEHFAF
>Mature_624_residues
SAGHPHRYSQDIINAGLTSIEETDMPQYKAPLRDMQFVLHELLNANEHYAKLPAFQENVSRELVDQYLEAAADFCENELS
PLNQVGDREGCTWNDGVVTTPTGFKEAYQKYIELGFPSLSAEEQYGGQGLPNSLGIAISEMVGSSNWAWGMYPGLSHGAV
RTLEHHGSEQQKDTYLPNLVSGVWTGTMCLTESHAGSDLGIIRSKAEPNEDGSYAISGEKIFISAGEHDMADNIIHIVLA
RLPGAPKGTKGISLFIVPKFLVNEDGSLGERNHVRCGSIEHKMGIHGNATCVINFDRAKGYLIGPENRGLNCMFTFMNTA
RIGTAVQGLAASESSFQGALTYAKDRLAMRSLSGPKAPEKDADPIIVHPAVRNMLLTQKAFAEGGRALVYLLAQYADVVE
HGITEEERKFADNILSLLTPIAKAFLTETGSESAKHGVQVFGGHGFISEHGMEQIVRDTRIACLYEGTTEIQALDLLGRK
VLQTQGAMLRDFTKIIHKFVEANKDNAAMKEFIEPLASLNKEWGDVTMQIGMRAMQNPDEVGAAAVDYLYFSGYVTLAYL
WARMAEVAQQKLAAGTTDADFYNAKVTTARFYFKKILPRVRSHVDVLSTGVESLMALDAEHFAF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557235, Length=373, Percent_Identity=28.686327077748, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI76496475, Length=377, Percent_Identity=28.1167108753316, Blast_Score=109, Evalue=6e-24,
Organism=Homo sapiens, GI21361497, Length=385, Percent_Identity=26.2337662337662, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI4501859, Length=461, Percent_Identity=22.9934924078091, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI226958412, Length=424, Percent_Identity=26.4150943396226, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI226958414, Length=385, Percent_Identity=26.7532467532467, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI4557233, Length=418, Percent_Identity=26.3157894736842, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI7656849, Length=384, Percent_Identity=27.6041666666667, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI4501857, Length=396, Percent_Identity=27.7777777777778, Blast_Score=95, Evalue=2e-19,
Organism=Homo sapiens, GI4557231, Length=314, Percent_Identity=28.0254777070064, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI187960098, Length=314, Percent_Identity=28.0254777070064, Blast_Score=82, Evalue=1e-15,
Organism=Escherichia coli, GI87082384, Length=318, Percent_Identity=28.9308176100629, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI87081958, Length=330, Percent_Identity=24.8484848484848, Blast_Score=67, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71985184, Length=441, Percent_Identity=26.530612244898, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17533517, Length=423, Percent_Identity=26.4775413711584, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI17508101, Length=366, Percent_Identity=25.9562841530055, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17569725, Length=378, Percent_Identity=28.8359788359788, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17534899, Length=376, Percent_Identity=28.1914893617021, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17506239, Length=370, Percent_Identity=26.4864864864865, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI86563383, Length=401, Percent_Identity=23.9401496259352, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI86563381, Length=401, Percent_Identity=23.9401496259352, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17538396, Length=412, Percent_Identity=23.5436893203883, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71985192, Length=326, Percent_Identity=27.3006134969325, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17570075, Length=365, Percent_Identity=24.6575342465753, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI71990804, Length=296, Percent_Identity=25.3378378378378, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17505929, Length=363, Percent_Identity=23.6914600550964, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32563615, Length=230, Percent_Identity=28.2608695652174, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21355753, Length=422, Percent_Identity=25.5924170616114, Blast_Score=102, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24666513, Length=413, Percent_Identity=24.9394673123487, Blast_Score=97, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24646207, Length=422, Percent_Identity=26.303317535545, Blast_Score=96, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21356377, Length=420, Percent_Identity=26.6666666666667, Blast_Score=96, Evalue=8e-20,
Organism=Drosophila melanogaster, GI281363737, Length=394, Percent_Identity=24.8730964467005, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24660351, Length=314, Percent_Identity=29.6178343949045, Blast_Score=91, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 68530; Mature: 68399

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGHPHRYSQDIINAGLTSIEETDMPQYKAPLRDMQFVLHELLNANEHYAKLPAFQENV
CCCCCCCHHHHHHHHHCCCCCHHCCCCHHHCCHHHHHHHHHHHHCCCCHHHHCCHHHHHH
SRELVDQYLEAAADFCENELSPLNQVGDREGCTWNDGVVTTPTGFKEAYQKYIELGFPSL
HHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCC
SAEEQYGGQGLPNSLGIAISEMVGSSNWAWGMYPGLSHGAVRTLEHHGSEQQKDTYLPNL
CCCHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
VSGVWTGTMCLTESHAGSDLGIIRSKAEPNEDGSYAISGEKIFISAGEHDMADNIIHIVL
HHHHHHCHHEEECCCCCCCCCEEECCCCCCCCCCEEECCCEEEEECCCCCHHHHHHHHHH
ARLPGAPKGTKGISLFIVPKFLVNEDGSLGERNHVRCGSIEHKMGIHGNATCVINFDRAK
HHCCCCCCCCCCEEEEEECHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
GYLIGPENRGLNCMFTFMNTARIGTAVQGLAASESSFQGALTYAKDRLAMRSLSGPKAPE
CEEECCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
KDADPIIVHPAVRNMLLTQKAFAEGGRALVYLLAQYADVVEHGITEEERKFADNILSLLT
CCCCCEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
PIAKAFLTETGSESAKHGVQVFGGHGFISEHGMEQIVRDTRIACLYEGTTEIQALDLLGR
HHHHHHHHCCCCHHHHCCCEEECCCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHH
KVLQTQGAMLRDFTKIIHKFVEANKDNAAMKEFIEPLASLNKEWGDVTMQIGMRAMQNPD
HHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCH
EVGAAAVDYLYFSGYVTLAYLWARMAEVAQQKLAAGTTDADFYNAKVTTARFYFKKILPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
VRSHVDVLSTGVESLMALDAEHFAF
HHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SAGHPHRYSQDIINAGLTSIEETDMPQYKAPLRDMQFVLHELLNANEHYAKLPAFQENV
CCCCCCHHHHHHHHHCCCCCHHCCCCHHHCCHHHHHHHHHHHHCCCCHHHHCCHHHHHH
SRELVDQYLEAAADFCENELSPLNQVGDREGCTWNDGVVTTPTGFKEAYQKYIELGFPSL
HHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCC
SAEEQYGGQGLPNSLGIAISEMVGSSNWAWGMYPGLSHGAVRTLEHHGSEQQKDTYLPNL
CCCHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHH
VSGVWTGTMCLTESHAGSDLGIIRSKAEPNEDGSYAISGEKIFISAGEHDMADNIIHIVL
HHHHHHCHHEEECCCCCCCCCEEECCCCCCCCCCEEECCCEEEEECCCCCHHHHHHHHHH
ARLPGAPKGTKGISLFIVPKFLVNEDGSLGERNHVRCGSIEHKMGIHGNATCVINFDRAK
HHCCCCCCCCCCEEEEEECHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCC
GYLIGPENRGLNCMFTFMNTARIGTAVQGLAASESSFQGALTYAKDRLAMRSLSGPKAPE
CEEECCCCCCCEEEEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
KDADPIIVHPAVRNMLLTQKAFAEGGRALVYLLAQYADVVEHGITEEERKFADNILSLLT
CCCCCEEECHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
PIAKAFLTETGSESAKHGVQVFGGHGFISEHGMEQIVRDTRIACLYEGTTEIQALDLLGR
HHHHHHHHCCCCHHHHCCCEEECCCCCHHHHHHHHHHHHHHEEEEECCCCHHHHHHHHHH
KVLQTQGAMLRDFTKIIHKFVEANKDNAAMKEFIEPLASLNKEWGDVTMQIGMRAMQNPD
HHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCH
EVGAAAVDYLYFSGYVTLAYLWARMAEVAQQKLAAGTTDADFYNAKVTTARFYFKKILPR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHH
VRSHVDVLSTGVESLMALDAEHFAF
HHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]