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The map label for this gene is clpX [H]

Identifier: 50083773

GI number: 50083773

Start: 522217

End: 523527

Strand: Direct

Name: clpX [H]

Synonym: ACIAD0535

Alternate gene names: 50083773

Gene position: 522217-523527 (Clockwise)

Preceding gene: 50083772

Following gene: 50083774

Centisome position: 14.51

GC content: 42.41

Gene sequence:

>1311_bases
ATGTCCGAACATCCTCAAGGACAAAAACACTGTTCATTTTGCGGTAAATCTCAGGCTGAAGTCGGAAAACTGATCGCAGG
CGAAAACGCTTATATTTGTAATGAATGTGTGGATGTGTGCTTGGATCTTGTTCAAACTAGCCAGCAAGTTGAAGCAGGGG
ATTGGGCAAGTCGAGATTTGCCAAAACCTCATGAAATTCGGGCGGCTTTAGATCAATATGTGATTGGTCAAGATCTGGCA
AAGAAAACGCTATCTGTTGCAGTGTATAACCATTACAAGCGTTTAAAGGCTGGTCAGTCTGGACATGTATCCAAGCACGA
AGTTGAAATTGCAAAAAGTAATATTTTACTGATTGGGCCAACGGGTTCAGGTAAGACTTTATTGGCACAGACGTTGGCGC
GTCTACTGGATGTGCCATTTGCAATGGCTGATGCCACCACACTGACCGAAGCAGGTTATGTGGGTGAAGATGTTGAAAAC
ATTGTACAGAAGCTTTTACAAAAAGCAGATTACGATGTTGAGAAAGCACAGAAAGGGATTATTTATATCGATGAGATCGA
TAAAATTACCCGCAAATCTGAAAATCCATCAATTACCCGTGACGTATCTGGCGAAGGCGTGCAACAGGCGCTATTGAAGA
TGATCGAAGGCACAGTTGCTTCGATTCCGCCACAAGGTGGTCGTAAGCATCCGCAGCAGGAATTTATTCAGATCGATACT
TCGAACATTCTGTTTATCTGTGGTGGTGCTTTTGCTGGTCTTGAAAAGATTGTTCAGCAGCGTCATGAAAAAGGTGGTAT
TGGTTTCAATGCCGAAGTGAAAAAGAAAGACGAAACCAAAAAGCTGGCTGAATTGTTCCGTCAGGTTGAGCCAACCGATT
TGGTGAAATTTGGATTAATTCCAGAGTTTATTGGTCGTCTGCCTGTTATTGCGACGCTTGAAGAGCTAGATGAAGCAGCA
TTGATGCAGATTCTAACTGAACCAAAAAATGCTTTAACGCGTCAATACCAGTCATTATTTCAAATGGAAAATGTTGATCT
GGTGTTTGAAGAGTCTGCATTACGAGCGATTGCCAAGAAAGCACTTGAGCGGAATACAGGGGCACGTGGTTTGCGCTCAA
TCATGGAAAATGTATTGCTTGAAACCATGTATGATTTGCCAAGCCGTAAGGATATTGGCACTGTCGTGGTGAATGAAGCT
GTGATTCGTGGTGAAGCAGAACCCGAGTACAAGAAAGAGCATACTCAAAAAAAAGATACCCATGAACATAACGTTGCTGA
TTTAAAGGTCATTGATTCTAAATCTGCATAA

Upstream 100 bases:

>100_bases
GATAACTTCATGACCGCACAAGCCGCAAAAGAATATGGTTTAGTGGATGAAGTTTTATCTAAGCGTCCCTAATAATTAAG
ATTTAAGTTGTGGAGTAGAT

Downstream 100 bases:

>100_bases
TGTTTCATTGGTCTGAAAAGCATGATTTGCCTCGGCATTTCATGCTTTTTTTATTGCAATTGTAAAGTGAGATGTTAATC
TAAATTTGAGATACGCATAG

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 436; Mature: 435

Protein sequence:

>436_residues
MSEHPQGQKHCSFCGKSQAEVGKLIAGENAYICNECVDVCLDLVQTSQQVEAGDWASRDLPKPHEIRAALDQYVIGQDLA
KKTLSVAVYNHYKRLKAGQSGHVSKHEVEIAKSNILLIGPTGSGKTLLAQTLARLLDVPFAMADATTLTEAGYVGEDVEN
IVQKLLQKADYDVEKAQKGIIYIDEIDKITRKSENPSITRDVSGEGVQQALLKMIEGTVASIPPQGGRKHPQQEFIQIDT
SNILFICGGAFAGLEKIVQQRHEKGGIGFNAEVKKKDETKKLAELFRQVEPTDLVKFGLIPEFIGRLPVIATLEELDEAA
LMQILTEPKNALTRQYQSLFQMENVDLVFEESALRAIAKKALERNTGARGLRSIMENVLLETMYDLPSRKDIGTVVVNEA
VIRGEAEPEYKKEHTQKKDTHEHNVADLKVIDSKSA

Sequences:

>Translated_436_residues
MSEHPQGQKHCSFCGKSQAEVGKLIAGENAYICNECVDVCLDLVQTSQQVEAGDWASRDLPKPHEIRAALDQYVIGQDLA
KKTLSVAVYNHYKRLKAGQSGHVSKHEVEIAKSNILLIGPTGSGKTLLAQTLARLLDVPFAMADATTLTEAGYVGEDVEN
IVQKLLQKADYDVEKAQKGIIYIDEIDKITRKSENPSITRDVSGEGVQQALLKMIEGTVASIPPQGGRKHPQQEFIQIDT
SNILFICGGAFAGLEKIVQQRHEKGGIGFNAEVKKKDETKKLAELFRQVEPTDLVKFGLIPEFIGRLPVIATLEELDEAA
LMQILTEPKNALTRQYQSLFQMENVDLVFEESALRAIAKKALERNTGARGLRSIMENVLLETMYDLPSRKDIGTVVVNEA
VIRGEAEPEYKKEHTQKKDTHEHNVADLKVIDSKSA
>Mature_435_residues
SEHPQGQKHCSFCGKSQAEVGKLIAGENAYICNECVDVCLDLVQTSQQVEAGDWASRDLPKPHEIRAALDQYVIGQDLAK
KTLSVAVYNHYKRLKAGQSGHVSKHEVEIAKSNILLIGPTGSGKTLLAQTLARLLDVPFAMADATTLTEAGYVGEDVENI
VQKLLQKADYDVEKAQKGIIYIDEIDKITRKSENPSITRDVSGEGVQQALLKMIEGTVASIPPQGGRKHPQQEFIQIDTS
NILFICGGAFAGLEKIVQQRHEKGGIGFNAEVKKKDETKKLAELFRQVEPTDLVKFGLIPEFIGRLPVIATLEELDEAAL
MQILTEPKNALTRQYQSLFQMENVDLVFEESALRAIAKKALERNTGARGLRSIMENVLLETMYDLPSRKDIGTVVVNEAV
IRGEAEPEYKKEHTQKKDTHEHNVADLKVIDSKSA

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=352, Percent_Identity=48.8636363636364, Blast_Score=332, Evalue=4e-91,
Organism=Escherichia coli, GI1786642, Length=400, Percent_Identity=70.5, Blast_Score=577, Evalue=1e-166,
Organism=Escherichia coli, GI1790366, Length=214, Percent_Identity=33.1775700934579, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=337, Percent_Identity=46.2908011869436, Blast_Score=293, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI71982905, Length=337, Percent_Identity=46.2908011869436, Blast_Score=292, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI71988663, Length=390, Percent_Identity=39.2307692307692, Blast_Score=258, Evalue=3e-69,
Organism=Caenorhabditis elegans, GI71988660, Length=250, Percent_Identity=40.4, Blast_Score=174, Evalue=9e-44,
Organism=Saccharomyces cerevisiae, GI6319704, Length=434, Percent_Identity=40.5529953917051, Blast_Score=285, Evalue=1e-77,
Organism=Drosophila melanogaster, GI24648291, Length=323, Percent_Identity=46.749226006192, Blast_Score=309, Evalue=2e-84,
Organism=Drosophila melanogaster, GI24648289, Length=323, Percent_Identity=46.749226006192, Blast_Score=309, Evalue=3e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 48182; Mature: 48050

Theoretical pI: Translated: 5.84; Mature: 5.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEHPQGQKHCSFCGKSQAEVGKLIAGENAYICNECVDVCLDLVQTSQQVEAGDWASRDL
CCCCCCCHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PKPHEIRAALDQYVIGQDLAKKTLSVAVYNHYKRLKAGQSGHVSKHEVEIAKSNILLIGP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEECCCEEEEEC
TGSGKTLLAQTLARLLDVPFAMADATTLTEAGYVGEDVENIVQKLLQKADYDVEKAQKGI
CCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
IYIDEIDKITRKSENPSITRDVSGEGVQQALLKMIEGTVASIPPQGGRKHPQQEFIQIDT
EEEEHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHEEECC
SNILFICGGAFAGLEKIVQQRHEKGGIGFNAEVKKKDETKKLAELFRQVEPTDLVKFGLI
CCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
PEFIGRLPVIATLEELDEAALMQILTEPKNALTRQYQSLFQMENVDLVFEESALRAIAKK
HHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHH
ALERNTGARGLRSIMENVLLETMYDLPSRKDIGTVVVNEAVIRGEAEPEYKKEHTQKKDT
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCC
HEHNVADLKVIDSKSA
CCCCCCEEEEECCCCC
>Mature Secondary Structure 
SEHPQGQKHCSFCGKSQAEVGKLIAGENAYICNECVDVCLDLVQTSQQVEAGDWASRDL
CCCCCCHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
PKPHEIRAALDQYVIGQDLAKKTLSVAVYNHYKRLKAGQSGHVSKHEVEIAKSNILLIGP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHEECCCEEEEEC
TGSGKTLLAQTLARLLDVPFAMADATTLTEAGYVGEDVENIVQKLLQKADYDVEKAQKGI
CCCCHHHHHHHHHHHHCCCHHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
IYIDEIDKITRKSENPSITRDVSGEGVQQALLKMIEGTVASIPPQGGRKHPQQEFIQIDT
EEEEHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCHHHCCCCCCCCCCCHHHHEEECC
SNILFICGGAFAGLEKIVQQRHEKGGIGFNAEVKKKDETKKLAELFRQVEPTDLVKFGLI
CCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
PEFIGRLPVIATLEELDEAALMQILTEPKNALTRQYQSLFQMENVDLVFEESALRAIAKK
HHHHCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHH
ALERNTGARGLRSIMENVLLETMYDLPSRKDIGTVVVNEAVIRGEAEPEYKKEHTQKKDT
HHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHCC
HEHNVADLKVIDSKSA
CCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA