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The map label for this gene is metX

Identifier: 50083767

GI number: 50083767

Start: 513308

End: 514471

Strand: Reverse

Name: metX

Synonym: ACIAD0529

Alternate gene names: 50083767

Gene position: 514471-513308 (Counterclockwise)

Preceding gene: 50083768

Following gene: 50083766

Centisome position: 14.3

GC content: 43.38

Gene sequence:

>1164_bases
GTGTCTTTTCCATCTGACTCAGTGGGGTTGGTTACTCCGCAAAAGTTCCAATTTGAAGAACCTCTGCATCTCGAATGTGG
TCGAGTGTTGCCACGTTTTGAGCTGATGGTTGAAACCTATGGCACCTTAAATGCAGACTATTCAAATGCAATTTTGATTT
GTCATGCACTTTCTGGTCACCATCATGCAGCAGGTTATCATCACGATGATGATAAAAAAGCAGGTTGGTGGGATGCCTGT
ATTGGTCCTGGCAAAGCCATTGATACCAATAAATTCTTTGTTGTTGCACTGAATAACATTGGTGGCTGCAATGGATCAAC
TGGCCCTACCTCACCCAATCCTGAAAATGAAAACCGCCCTTACGGCCCAGATTTTCCACTGGTGACGGTGCGTGACTGGG
TTAAAACACAAGCATTACTTTCGGATCACTTAGGTATCCAGAGCTGGTATGCAGTGATTGGCGGTTCATTGGGCGGGATG
CAGGCTTTACAGTGGTCAGTCGATTATCCTGATCGTCTCAAAAACTGTGTGATTATTGCCAGTGCACCAAAGCTTTCTGC
ACAAAATATTGCCTTTAATGAAGTTGCCCGCCAATCGATTCTTTCCGACCCAGATTTTTATCACGGTCGTTATTTAGAGC
ATGACAGCTATCCCAAACGTGGTTTAATTTTAGCTCGAATGGTCGGACATATTACCTATTTGTCTGAAGAAGCCATGAAA
CAAAAATTTGGTCGTGACCTCAAATCGGGCAAATTTATGTATGGCTTTGATGTCGAGTTTCAGGTCGAAAGTTATTTACG
CTATCAAGGCGAGCAATTTAGCCGAAACTTTGATGCCAATACTTATCTGATTATGACCAAGGCATTGGATTATTTTGATC
CTTCTCGTGAGTATGAACAATCTCTAACCAAGGCTATGGCGCAAACGCAATGCCGCTTTTTAGTGGTGTCATTTACCACC
GACTGGCGTTTTGCACCAGAAAGATCCCAAGAAATTGTAGATGCACTCATCACCAACCATAAACCCGTCACTTATCTGGA
CGTAGATGCTGAACAGGGACATGATTCATTTCTGTTTCCGATTCCGCTTTACGTGAAAACACTTCGTGCATTTTTAGGCG
GTGAAGCACATTTAAAATCGACACCTCAAGTGGAGATCAACTGA

Upstream 100 bases:

>100_bases
GCTGCCGCAGTTTAATCTCGGTAAAAGACTCTTTTTGAAAGGATACCTATGGTATCCTTTCTTTTATTATTGATTTAAAG
ATAAAAGGCGAATTGCTCCC

Downstream 100 bases:

>100_bases
TGCGTATTGACCAACAACTTGCAGAAACGTGGATTAAACCAGGCTCAAGCGTACTAGATTTAGGCTGTGGAGATGGTGAA
TTATTGGCTCATATGAGTAA

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MSFPSDSVGLVTPQKFQFEEPLHLECGRVLPRFELMVETYGTLNADYSNAILICHALSGHHHAAGYHHDDDKKAGWWDAC
IGPGKAIDTNKFFVVALNNIGGCNGSTGPTSPNPENENRPYGPDFPLVTVRDWVKTQALLSDHLGIQSWYAVIGGSLGGM
QALQWSVDYPDRLKNCVIIASAPKLSAQNIAFNEVARQSILSDPDFYHGRYLEHDSYPKRGLILARMVGHITYLSEEAMK
QKFGRDLKSGKFMYGFDVEFQVESYLRYQGEQFSRNFDANTYLIMTKALDYFDPSREYEQSLTKAMAQTQCRFLVVSFTT
DWRFAPERSQEIVDALITNHKPVTYLDVDAEQGHDSFLFPIPLYVKTLRAFLGGEAHLKSTPQVEIN

Sequences:

>Translated_387_residues
MSFPSDSVGLVTPQKFQFEEPLHLECGRVLPRFELMVETYGTLNADYSNAILICHALSGHHHAAGYHHDDDKKAGWWDAC
IGPGKAIDTNKFFVVALNNIGGCNGSTGPTSPNPENENRPYGPDFPLVTVRDWVKTQALLSDHLGIQSWYAVIGGSLGGM
QALQWSVDYPDRLKNCVIIASAPKLSAQNIAFNEVARQSILSDPDFYHGRYLEHDSYPKRGLILARMVGHITYLSEEAMK
QKFGRDLKSGKFMYGFDVEFQVESYLRYQGEQFSRNFDANTYLIMTKALDYFDPSREYEQSLTKAMAQTQCRFLVVSFTT
DWRFAPERSQEIVDALITNHKPVTYLDVDAEQGHDSFLFPIPLYVKTLRAFLGGEAHLKSTPQVEIN
>Mature_386_residues
SFPSDSVGLVTPQKFQFEEPLHLECGRVLPRFELMVETYGTLNADYSNAILICHALSGHHHAAGYHHDDDKKAGWWDACI
GPGKAIDTNKFFVVALNNIGGCNGSTGPTSPNPENENRPYGPDFPLVTVRDWVKTQALLSDHLGIQSWYAVIGGSLGGMQ
ALQWSVDYPDRLKNCVIIASAPKLSAQNIAFNEVARQSILSDPDFYHGRYLEHDSYPKRGLILARMVGHITYLSEEAMKQ
KFGRDLKSGKFMYGFDVEFQVESYLRYQGEQFSRNFDANTYLIMTKALDYFDPSREYEQSLTKAMAQTQCRFLVVSFTTD
WRFAPERSQEIVDALITNHKPVTYLDVDAEQGHDSFLFPIPLYVKTLRAFLGGEAHLKSTPQVEIN

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=237, Percent_Identity=38.8185654008439, Blast_Score=158, Evalue=1e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_ACIAD (Q6FEQ3)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_045277.1
- ProteinModelPortal:   Q6FEQ3
- SMR:   Q6FEQ3
- STRING:   Q6FEQ3
- GeneID:   2879496
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0529
- NMPDR:   fig|62977.3.peg.1292
- eggNOG:   COG2021
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- PhylomeDB:   Q6FEQ3
- ProtClustDB:   PRK00175
- BioCyc:   ASP62977:ACIAD0529-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 43672; Mature: 43540

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: ACT_SITE 156-156 ACT_SITE 354-354

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPSDSVGLVTPQKFQFEEPLHLECGRVLPRFELMVETYGTLNADYSNAILICHALSGH
CCCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
HHAAGYHHDDDKKAGWWDACIGPGKAIDTNKFFVVALNNIGGCNGSTGPTSPNPENENRP
CCCCCCCCCCCCCCCCHHHHCCCCCEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCC
YGPDFPLVTVRDWVKTQALLSDHLGIQSWYAVIGGSLGGMQALQWSVDYPDRLKNCVIIA
CCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEECCCCHHHHCCEEEEE
SAPKLSAQNIAFNEVARQSILSDPDFYHGRYLEHDSYPKRGLILARMVGHITYLSEEAMK
ECCCCCCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
QKFGRDLKSGKFMYGFDVEFQVESYLRYQGEQFSRNFDANTYLIMTKALDYFDPSREYEQ
HHHCCHHHCCCEEEEEEEEEEHHHHHHHCCHHHCCCCCCCEEEEEEEHHHHCCCCHHHHH
SLTKAMAQTQCRFLVVSFTTDWRFAPERSQEIVDALITNHKPVTYLDVDAEQGHDSFLFP
HHHHHHHHCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEC
IPLYVKTLRAFLGGEAHLKSTPQVEIN
HHHHHHHHHHHHCCCCCCCCCCCEEEC
>Mature Secondary Structure 
SFPSDSVGLVTPQKFQFEEPLHLECGRVLPRFELMVETYGTLNADYSNAILICHALSGH
CCCCCCCCCCCCCCCCCCCCCCCHHCCCCHHHHHHHHHHCCCCCCCCCEEEEEEECCCC
HHAAGYHHDDDKKAGWWDACIGPGKAIDTNKFFVVALNNIGGCNGSTGPTSPNPENENRP
CCCCCCCCCCCCCCCCHHHHCCCCCEECCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCC
YGPDFPLVTVRDWVKTQALLSDHLGIQSWYAVIGGSLGGMQALQWSVDYPDRLKNCVIIA
CCCCCCEEEHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCEEEEECCCCHHHHCCEEEEE
SAPKLSAQNIAFNEVARQSILSDPDFYHGRYLEHDSYPKRGLILARMVGHITYLSEEAMK
ECCCCCCCCCHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHH
QKFGRDLKSGKFMYGFDVEFQVESYLRYQGEQFSRNFDANTYLIMTKALDYFDPSREYEQ
HHHCCHHHCCCEEEEEEEEEEHHHHHHHCCHHHCCCCCCCEEEEEEEHHHHCCCCHHHHH
SLTKAMAQTQCRFLVVSFTTDWRFAPERSQEIVDALITNHKPVTYLDVDAEQGHDSFLFP
HHHHHHHHCCEEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCEEEC
IPLYVKTLRAFLGGEAHLKSTPQVEIN
HHHHHHHHHHHHCCCCCCCCCCCEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA