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The map label for this gene is 50083699

Identifier: 50083699

GI number: 50083699

Start: 446311

End: 447363

Strand: Direct

Name: 50083699

Synonym: ACIAD0450

Alternate gene names: NA

Gene position: 446311-447363 (Clockwise)

Preceding gene: 50083698

Following gene: 50083701

Centisome position: 12.4

GC content: 45.49

Gene sequence:

>1053_bases
ATGAAAGAGAAGCCGACATTAACTTATCAATTGCCGACTAAATCTTGTTTGACCCATACATGGAGTAAGCCTTCTTTTCA
TTATGTAGATTCTGAGCAAGCGGGGCCAGCCCGTTTCTATAATCAGGTGAAACGTCCGTCTGCGCGTGGTTCGACTGAAC
TTCTGCGTTGGTTAGCGACGCGTGAATCATACACATGGCAGGTCGACATATCTCGTGAATATGAGCTGCGCCTTAACACG
CCTATTGCCATTCCACAAAATCGGCCACATGCCAGCTTAGACGACTGGCAAGTATGGTTTGTTGGTCATGCAACAGTACT
GCTTCAGATTGGGCCATATAATTTTATTACCGATCCAGTCTGGTGCGAATATGCCAGTCCTCACCAAGGTCGTGGCCCGC
GTCGGGTTTGCCCAGCAGGAATTGCACTGGAACACTTGCCCACAATTCACGCCGTGTTGCTCAGCCACAATCATTATGAT
CATATGGATCTGGCGACACTGGAATGGCTACATCGTAAATTCGCAATGCCCATCTATACTGGATTAGGAAATCAATATTA
TTTACCCAAAGACTATCATGTGATTGAGATGGACTGGTGGCAGATGATCCCGTTTCACGATCTCACCATTATGTATACGC
CAGCTCAACACGGTTCAGGTCGTGGTATACGTGATCAAGGCAAAGCCTTGTGGGGTGGGTTTTCAGTTATTGCAGAATCA
GGTCACGCTTTTTTTGCTGGCGACACAGGTTATGGGCCACATTTTAAAGAAATTTATGAGCGTTGTGGTGCCCCTCGAAT
TGCATTGTTACCAATCGGAGCCTATGAACCGCGCGATTTGATGCAGTATGTCCATATGAATCCACAAGATGCTCTGCATG
CACATCTAGATTTACATGCACAACGAACCATGGCAATTCATTATCGAACATTTCAGCTCACAGATGAACATCGTGATGAT
CCAGAGCGTGAACTTACGCATCTGTTAAAAACCTCATCTAAATTGGTCAATCCATTTTACTGTATCCGTGAAGGACATAA
GCTCACTGTTTAA

Upstream 100 bases:

>100_bases
TTAAATCAACAAAACGGAGAAATAGTCGCTGCTAAAGTTAAATGAAAAACATGCGTAAAAATATGTTTATTTGACCACGA
GATGATGACTGAAATCACCT

Downstream 100 bases:

>100_bases
AGCTTTTTGTTTGCAATAAAAAACCACCCGCAGGTGGTTTTTTATTGCTTTTCTATTATAAGAAACCAGGATGACCTTTA
GCAGGATCACTGTCACGGGC

Product: Zn-dependent hydrolase of the beta-lactamase fold

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MKEKPTLTYQLPTKSCLTHTWSKPSFHYVDSEQAGPARFYNQVKRPSARGSTELLRWLATRESYTWQVDISREYELRLNT
PIAIPQNRPHASLDDWQVWFVGHATVLLQIGPYNFITDPVWCEYASPHQGRGPRRVCPAGIALEHLPTIHAVLLSHNHYD
HMDLATLEWLHRKFAMPIYTGLGNQYYLPKDYHVIEMDWWQMIPFHDLTIMYTPAQHGSGRGIRDQGKALWGGFSVIAES
GHAFFAGDTGYGPHFKEIYERCGAPRIALLPIGAYEPRDLMQYVHMNPQDALHAHLDLHAQRTMAIHYRTFQLTDEHRDD
PERELTHLLKTSSKLVNPFYCIREGHKLTV

Sequences:

>Translated_350_residues
MKEKPTLTYQLPTKSCLTHTWSKPSFHYVDSEQAGPARFYNQVKRPSARGSTELLRWLATRESYTWQVDISREYELRLNT
PIAIPQNRPHASLDDWQVWFVGHATVLLQIGPYNFITDPVWCEYASPHQGRGPRRVCPAGIALEHLPTIHAVLLSHNHYD
HMDLATLEWLHRKFAMPIYTGLGNQYYLPKDYHVIEMDWWQMIPFHDLTIMYTPAQHGSGRGIRDQGKALWGGFSVIAES
GHAFFAGDTGYGPHFKEIYERCGAPRIALLPIGAYEPRDLMQYVHMNPQDALHAHLDLHAQRTMAIHYRTFQLTDEHRDD
PERELTHLLKTSSKLVNPFYCIREGHKLTV
>Mature_350_residues
MKEKPTLTYQLPTKSCLTHTWSKPSFHYVDSEQAGPARFYNQVKRPSARGSTELLRWLATRESYTWQVDISREYELRLNT
PIAIPQNRPHASLDDWQVWFVGHATVLLQIGPYNFITDPVWCEYASPHQGRGPRRVCPAGIALEHLPTIHAVLLSHNHYD
HMDLATLEWLHRKFAMPIYTGLGNQYYLPKDYHVIEMDWWQMIPFHDLTIMYTPAQHGSGRGIRDQGKALWGGFSVIAES
GHAFFAGDTGYGPHFKEIYERCGAPRIALLPIGAYEPRDLMQYVHMNPQDALHAHLDLHAQRTMAIHYRTFQLTDEHRDD
PERELTHLLKTSSKLVNPFYCIREGHKLTV

Specific function: Unknown

COG id: COG2220

COG function: function code R; Predicted Zn-dependent hydrolases of the beta-lactamase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To K.pneumoniae romA [H]

Homologues:

Organism=Homo sapiens, GI170932483, Length=331, Percent_Identity=36.8580060422961, Blast_Score=199, Evalue=2e-51,
Organism=Homo sapiens, GI170932481, Length=331, Percent_Identity=36.8580060422961, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI17543102, Length=285, Percent_Identity=31.9298245614035, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI25148824, Length=285, Percent_Identity=31.9298245614035, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17543100, Length=285, Percent_Identity=31.9298245614035, Blast_Score=145, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17543104, Length=256, Percent_Identity=33.203125, Blast_Score=144, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6325154, Length=261, Percent_Identity=30.6513409961686, Blast_Score=116, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 40519; Mature: 40519

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEKPTLTYQLPTKSCLTHTWSKPSFHYVDSEQAGPARFYNQVKRPSARGSTELLRWLAT
CCCCCCEEEECCCHHHHHHCCCCCCEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
RESYTWQVDISREYELRLNTPIAIPQNRPHASLDDWQVWFVGHATVLLQIGPYNFITDPV
CCCEEEEEEECCEEEEEECCEEECCCCCCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCE
WCEYASPHQGRGPRRVCPAGIALEHLPTIHAVLLSHNHYDHMDLATLEWLHRKFAMPIYT
EECCCCCCCCCCCCCCCCCCCHHHHCCHHEEHEEECCCCCCCHHHHHHHHHHHHCCHHEE
GLGNQYYLPKDYHVIEMDWWQMIPFHDLTIMYTPAQHGSGRGIRDQGKALWGGFSVIAES
CCCCEEECCCCCEEEEECCEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHCCHHHEECC
GHAFFAGDTGYGPHFKEIYERCGAPRIALLPIGAYEPRDLMQYVHMNPQDALHAHLDLHA
CCEEEECCCCCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHEEEC
QRTMAIHYRTFQLTDEHRDDPERELTHLLKTSSKLVNPFYCIREGHKLTV
CEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCEECC
>Mature Secondary Structure
MKEKPTLTYQLPTKSCLTHTWSKPSFHYVDSEQAGPARFYNQVKRPSARGSTELLRWLAT
CCCCCCEEEECCCHHHHHHCCCCCCEEECCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHH
RESYTWQVDISREYELRLNTPIAIPQNRPHASLDDWQVWFVGHATVLLQIGPYNFITDPV
CCCEEEEEEECCEEEEEECCEEECCCCCCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCE
WCEYASPHQGRGPRRVCPAGIALEHLPTIHAVLLSHNHYDHMDLATLEWLHRKFAMPIYT
EECCCCCCCCCCCCCCCCCCCHHHHCCHHEEHEEECCCCCCCHHHHHHHHHHHHCCHHEE
GLGNQYYLPKDYHVIEMDWWQMIPFHDLTIMYTPAQHGSGRGIRDQGKALWGGFSVIAES
CCCCEEECCCCCEEEEECCEEECCCCCEEEEEECCCCCCCCCCCCCCCCHHCCHHHEECC
GHAFFAGDTGYGPHFKEIYERCGAPRIALLPIGAYEPRDLMQYVHMNPQDALHAHLDLHA
CCEEEECCCCCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHEEEC
QRTMAIHYRTFQLTDEHRDDPERELTHLLKTSSKLVNPFYCIREGHKLTV
CEEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]