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The map label for this gene is aidB [H]

Identifier: 50083701

GI number: 50083701

Start: 449533

End: 451179

Strand: Direct

Name: aidB [H]

Synonym: ACIAD0452

Alternate gene names: 50083701

Gene position: 449533-451179 (Clockwise)

Preceding gene: 50083699

Following gene: 50083704

Centisome position: 12.49

GC content: 45.05

Gene sequence:

>1647_bases
ATGATGACAAGGATACCCGATCAGTCTGATAACCAATTTAATGAATTATGTAACTACAATTTATATCAAAGCGATGTGCC
TTTACAGGAAATTCTGAAACGTTATGGACATCACGAGCAGAAACAGCTTACAACGTTTGGCGAAATACTTGGTCATCAAC
GTAGTTATATGCTGGCAGATCAAGCCAATCGACATTTACCACAATTGCATGGTTTTGATGCGCGTGGCCGACGAATCGAT
GAAGTTGAGTTTCATCCCGCCTGGCATCAATGGATGCGACAAAATCGTGAATATGCATTACATGCACATCCATTTATTAC
AAGCGCTGCTCAAACGGGTTGGGTGGAGTGGGCTGCGCGTTTTTATTTGAGTGGCCAGGTTGAAAGTGGCAGTTTGTGTC
CGAGCGCAATGACATTAGGAAGTATTCCCTTGATTCAACGCGAATCTAAATTATGGCAAACCTTAGGTAAAAAACTGCTT
TCTTGTGACTATGATGAACGAGATATACTCATCTCCCAGAAATCATCAATCTGGGTTGGAATGGGAATGACCGAAAAGCA
GGGTGGCTCGGATGTGCGTGCCAATCAAACATTCGCCAAGCCCGTTGGTATTTCAGGTCGTGGAGAGGAATATTTATTGA
CGGGGCATAAATGGTTTTTTTCTGCACCCATGTCGGATGCGCATTTGGTGGTCGCACAAACTTCACAAGAGGAACTCGCC
TGTTTTTTTGTGCCGCGTTGGTTATCAAATGGGAGTAAAAACCATATTGAGATTCAGCAGCTCAAAAATAAGGTGGGCAA
TAAAAGTAATTCCAGTAGTGAAGTCGAATTTCGCGATGCATTGGGCATTATGATTGGAGAGGAAGGGCGAGGTATTCCCA
CGATTATCGAGATGGCAACCTATACCCGTTTAACATGTTCGGTTGGAAGTACAGCGATACTTCGTCAGGCTTTGGTACAA
TGTATCGCTTACACACGTCAGCGTCGTGCATTTGGTCGAGTTCTTGCAGATCAACCGCTTATGCAGGCAGTTCTGACCGA
TATGGCACTGGAAACTGAAGCAGCGCTACACTTGAGCATGCATTTGGCAGCATGCTACCAACGTGATGATGACATCTCAC
AGGCATGGGTACGGTTATTGACGCCAGCAGCCAAGTTCTGGATCTGTAAGCGTGCTGTTGAGTTGACTGGCGAAGCTATG
GAGGTGTTTGGTGGCAACGGTTATGTCGAGACAGGCATAATGTCTCGGCTGTTTAAAGAAGCACCTGTTAATTCAATTTG
GGAAGGCTCAGGAAATATTATGTGTCTGGATGTGCTTAGGGCAATACAGCGTCATCCTGAATCTATTCAGGTTTTATTCG
ATTCATTTGGCGATGTAACTGCGCAAGAGTCTTGCTTGTATCAGGACCTTCAGGCGTTGAAAGATGAGTTGCAATATTCT
AGTGAGCAATTGCAGTTTAGCGCCCGTCACTTTGTTAGCCGTTTGGTGCTGCTGACACAAGCCGTATTGATGAGGCGCTA
CGCTCCCCATTGGGTATCCGATGCATTTATCCAGTCTCGTTATGGTACTTGGCATGGACGAGTGACTGGAATATTACCCG
TTATGCCAGATTCCAAACTAATTTTGGAGCGTGCATATCCAGAATAA

Upstream 100 bases:

>100_bases
TCATATGTTTGGAAAATAAAGATCATCATGACCTATGTGCCCAAAATTCTGGTATATCTAGAAAACCATCTAGAAATAAA
ATAAACCATGGATAAGTCGC

Downstream 100 bases:

>100_bases
AATTTTCAATTAAAAAAGGGCAAATGATTTGCCCTTTTCTGATGAAGCCTAATTTAAACTGATACCAATCTGTTAGATTT
GACCATGTCGCCAAGCCCGT

Product: acyl-CoA dehydrogenase (AidB)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MMTRIPDQSDNQFNELCNYNLYQSDVPLQEILKRYGHHEQKQLTTFGEILGHQRSYMLADQANRHLPQLHGFDARGRRID
EVEFHPAWHQWMRQNREYALHAHPFITSAAQTGWVEWAARFYLSGQVESGSLCPSAMTLGSIPLIQRESKLWQTLGKKLL
SCDYDERDILISQKSSIWVGMGMTEKQGGSDVRANQTFAKPVGISGRGEEYLLTGHKWFFSAPMSDAHLVVAQTSQEELA
CFFVPRWLSNGSKNHIEIQQLKNKVGNKSNSSSEVEFRDALGIMIGEEGRGIPTIIEMATYTRLTCSVGSTAILRQALVQ
CIAYTRQRRAFGRVLADQPLMQAVLTDMALETEAALHLSMHLAACYQRDDDISQAWVRLLTPAAKFWICKRAVELTGEAM
EVFGGNGYVETGIMSRLFKEAPVNSIWEGSGNIMCLDVLRAIQRHPESIQVLFDSFGDVTAQESCLYQDLQALKDELQYS
SEQLQFSARHFVSRLVLLTQAVLMRRYAPHWVSDAFIQSRYGTWHGRVTGILPVMPDSKLILERAYPE

Sequences:

>Translated_548_residues
MMTRIPDQSDNQFNELCNYNLYQSDVPLQEILKRYGHHEQKQLTTFGEILGHQRSYMLADQANRHLPQLHGFDARGRRID
EVEFHPAWHQWMRQNREYALHAHPFITSAAQTGWVEWAARFYLSGQVESGSLCPSAMTLGSIPLIQRESKLWQTLGKKLL
SCDYDERDILISQKSSIWVGMGMTEKQGGSDVRANQTFAKPVGISGRGEEYLLTGHKWFFSAPMSDAHLVVAQTSQEELA
CFFVPRWLSNGSKNHIEIQQLKNKVGNKSNSSSEVEFRDALGIMIGEEGRGIPTIIEMATYTRLTCSVGSTAILRQALVQ
CIAYTRQRRAFGRVLADQPLMQAVLTDMALETEAALHLSMHLAACYQRDDDISQAWVRLLTPAAKFWICKRAVELTGEAM
EVFGGNGYVETGIMSRLFKEAPVNSIWEGSGNIMCLDVLRAIQRHPESIQVLFDSFGDVTAQESCLYQDLQALKDELQYS
SEQLQFSARHFVSRLVLLTQAVLMRRYAPHWVSDAFIQSRYGTWHGRVTGILPVMPDSKLILERAYPE
>Mature_548_residues
MMTRIPDQSDNQFNELCNYNLYQSDVPLQEILKRYGHHEQKQLTTFGEILGHQRSYMLADQANRHLPQLHGFDARGRRID
EVEFHPAWHQWMRQNREYALHAHPFITSAAQTGWVEWAARFYLSGQVESGSLCPSAMTLGSIPLIQRESKLWQTLGKKLL
SCDYDERDILISQKSSIWVGMGMTEKQGGSDVRANQTFAKPVGISGRGEEYLLTGHKWFFSAPMSDAHLVVAQTSQEELA
CFFVPRWLSNGSKNHIEIQQLKNKVGNKSNSSSEVEFRDALGIMIGEEGRGIPTIIEMATYTRLTCSVGSTAILRQALVQ
CIAYTRQRRAFGRVLADQPLMQAVLTDMALETEAALHLSMHLAACYQRDDDISQAWVRLLTPAAKFWICKRAVELTGEAM
EVFGGNGYVETGIMSRLFKEAPVNSIWEGSGNIMCLDVLRAIQRHPESIQVLFDSFGDVTAQESCLYQDLQALKDELQYS
SEQLQFSARHFVSRLVLLTQAVLMRRYAPHWVSDAFIQSRYGTWHGRVTGILPVMPDSKLILERAYPE

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI226958412, Length=280, Percent_Identity=23.9285714285714, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI226958414, Length=280, Percent_Identity=23.9285714285714, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI4557231, Length=315, Percent_Identity=22.5396825396825, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI187960098, Length=315, Percent_Identity=22.5396825396825, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI4557233, Length=259, Percent_Identity=25.0965250965251, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI7656849, Length=272, Percent_Identity=26.1029411764706, Blast_Score=69, Evalue=9e-12,
Organism=Homo sapiens, GI4501857, Length=279, Percent_Identity=26.1648745519713, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI87082384, Length=519, Percent_Identity=43.9306358381503, Blast_Score=392, Evalue=1e-110,
Organism=Escherichia coli, GI87081958, Length=268, Percent_Identity=26.4925373134328, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI86563383, Length=493, Percent_Identity=27.5862068965517, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI86563381, Length=493, Percent_Identity=27.5862068965517, Blast_Score=166, Evalue=3e-41,
Organism=Caenorhabditis elegans, GI17538396, Length=274, Percent_Identity=24.0875912408759, Blast_Score=85, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17505929, Length=321, Percent_Identity=26.4797507788162, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17569725, Length=278, Percent_Identity=24.4604316546763, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17551932, Length=314, Percent_Identity=25.796178343949, Blast_Score=74, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17508101, Length=259, Percent_Identity=25.4826254826255, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17506239, Length=268, Percent_Identity=24.2537313432836, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356377, Length=292, Percent_Identity=23.972602739726, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21355753, Length=265, Percent_Identity=21.5094339622642, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24660351, Length=272, Percent_Identity=24.6323529411765, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281363737, Length=311, Percent_Identity=21.8649517684887, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: NA

Molecular weight: Translated: 62177; Mature: 62177

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00072 ACYL_COA_DH_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTRIPDQSDNQFNELCNYNLYQSDVPLQEILKRYGHHEQKQLTTFGEILGHQRSYMLAD
CCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHH
QANRHLPQLHGFDARGRRIDEVEFHPAWHQWMRQNREYALHAHPFITSAAQTGWVEWAAR
HHHCCCCHHCCCCCCCCCCCCEEECHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHH
FYLSGQVESGSLCPSAMTLGSIPLIQRESKLWQTLGKKLLSCDYDERDILISQKSSIWVG
HHEECCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEE
MGMTEKQGGSDVRANQTFAKPVGISGRGEEYLLTGHKWFFSAPMSDAHLVVAQTSQEELA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCCEEEEEECCCCCEE
CFFVPRWLSNGSKNHIEIQQLKNKVGNKSNSSSEVEFRDALGIMIGEEGRGIPTIIEMAT
EEEEEHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEHHHHHCEEECCCCCCCHHHHHHHH
YTRLTCSVGSTAILRQALVQCIAYTRQRRAFGRVLADQPLMQAVLTDMALETEAALHLSM
HHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
HLAACYQRDDDISQAWVRLLTPAAKFWICKRAVELTGEAMEVFGGNGYVETGIMSRLFKE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEHHHHHHHHHHH
APVNSIWEGSGNIMCLDVLRAIQRHPESIQVLFDSFGDVTAQESCLYQDLQALKDELQYS
CCCCCEECCCCCEEHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
SEQLQFSARHFVSRLVLLTQAVLMRRYAPHWVSDAFIQSRYGTWHGRVTGILPVMPDSKL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCHH
ILERAYPE
HHHCCCCC
>Mature Secondary Structure
MMTRIPDQSDNQFNELCNYNLYQSDVPLQEILKRYGHHEQKQLTTFGEILGHQRSYMLAD
CCCCCCCCCCCHHHHHHCCCCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHH
QANRHLPQLHGFDARGRRIDEVEFHPAWHQWMRQNREYALHAHPFITSAAQTGWVEWAAR
HHHCCCCHHCCCCCCCCCCCCEEECHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHH
FYLSGQVESGSLCPSAMTLGSIPLIQRESKLWQTLGKKLLSCDYDERDILISQKSSIWVG
HHEECCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCEEEE
MGMTEKQGGSDVRANQTFAKPVGISGRGEEYLLTGHKWFFSAPMSDAHLVVAQTSQEELA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCEEEEECCCCCCEEEEEECCCCCEE
CFFVPRWLSNGSKNHIEIQQLKNKVGNKSNSSSEVEFRDALGIMIGEEGRGIPTIIEMAT
EEEEEHHHCCCCCCCCHHHHHHHHHCCCCCCCCCEEHHHHHCEEECCCCCCCHHHHHHHH
YTRLTCSVGSTAILRQALVQCIAYTRQRRAFGRVLADQPLMQAVLTDMALETEAALHLSM
HHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
HLAACYQRDDDISQAWVRLLTPAAKFWICKRAVELTGEAMEVFGGNGYVETGIMSRLFKE
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCEEHHHHHHHHHHH
APVNSIWEGSGNIMCLDVLRAIQRHPESIQVLFDSFGDVTAQESCLYQDLQALKDELQYS
CCCCCEECCCCCEEHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCC
SEQLQFSARHFVSRLVLLTQAVLMRRYAPHWVSDAFIQSRYGTWHGRVTGILPVMPDSKL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCEEEEEEECCCCCHH
ILERAYPE
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]