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The map label for this gene is ahpC [H]

Identifier: 50083688

GI number: 50083688

Start: 432824

End: 433387

Strand: Reverse

Name: ahpC [H]

Synonym: ACIAD0436

Alternate gene names: 50083688

Gene position: 433387-432824 (Counterclockwise)

Preceding gene: 50083689

Following gene: 50083686

Centisome position: 12.04

GC content: 39.36

Gene sequence:

>564_bases
ATGAGTTTAATCAATACCGAAATCAAACCTTTTCAAGCGACTGCATATCAAAATGGTCAATTTATCGATATTTCCGAAGC
TGACTTAAAAGGAAAATGGTCTGTGGTATTTTTTTACCCTGCTGACTTTACCTTTGTGTGTCCAACGGAACTTGAAGACC
TTGCAGATCAATATGCAGAGTTTCAGAAGCTAGGTGTCGATATCTACTCTGTTTCTACAGATACTCACTTCACCCATAAA
GCATGGCATGATACATCAGATGCCATTGGTAAAATCCAATATGCCATGATTGGTGACCCAACTTGGACCATTTCTAAAAA
CTTTGAAGTTTTAATTGAAGCTGAAGGTTTGGCTGATCGTGGAACATTTGTAATTGATCCAGAAGGTAAAATCCAAATTG
TTGAAATCAATGCGGGTGGAATTGGCCGTGACGCACAAGAACTGCTACGTAAAGTAAAAGCAGCCGTATACGTTTACAAT
CATCCAGGTGAAGTCTGTCCTGCCAAATGGAAAGAAGGTGATGCAACACTTGCACCATCGATTGATCTAGTGGGTAAAAT
CTAA

Upstream 100 bases:

>100_bases
ATCAATTTTATAAAAAATTTCTGTTTTTACGATTTATATAAATGCGTTATCTTGGTTGCCACATTAAGAACTTTCTCACG
CCATTAAGAGGATCAAGATA

Downstream 100 bases:

>100_bases
ACCTATATCACTTTAAGCTATGAACCACTTCCCAAACAGGAAGTGGTTTTTGTATTTAAGATCGTATACAGCACTGCCGT
TGCAATAATGGAATCAGCCA

Product: alkyl hydroperoxide reductase protein

Products: NA

Alternate protein names: Alkyl hydroperoxide reductase protein C22; Peroxiredoxin; SCRP-23; Sulfate starvation-induced protein 8; SSI8; Thioredoxin peroxidase [H]

Number of amino acids: Translated: 187; Mature: 186

Protein sequence:

>187_residues
MSLINTEIKPFQATAYQNGQFIDISEADLKGKWSVVFFYPADFTFVCPTELEDLADQYAEFQKLGVDIYSVSTDTHFTHK
AWHDTSDAIGKIQYAMIGDPTWTISKNFEVLIEAEGLADRGTFVIDPEGKIQIVEINAGGIGRDAQELLRKVKAAVYVYN
HPGEVCPAKWKEGDATLAPSIDLVGKI

Sequences:

>Translated_187_residues
MSLINTEIKPFQATAYQNGQFIDISEADLKGKWSVVFFYPADFTFVCPTELEDLADQYAEFQKLGVDIYSVSTDTHFTHK
AWHDTSDAIGKIQYAMIGDPTWTISKNFEVLIEAEGLADRGTFVIDPEGKIQIVEINAGGIGRDAQELLRKVKAAVYVYN
HPGEVCPAKWKEGDATLAPSIDLVGKI
>Mature_186_residues
SLINTEIKPFQATAYQNGQFIDISEADLKGKWSVVFFYPADFTFVCPTELEDLADQYAEFQKLGVDIYSVSTDTHFTHKA
WHDTSDAIGKIQYAMIGDPTWTISKNFEVLIEAEGLADRGTFVIDPEGKIQIVEINAGGIGRDAQELLRKVKAAVYVYNH
PGEVCPAKWKEGDATLAPSIDLVGKI

Specific function: Directly reduces organic hydroperoxides in its reduced dithiol form [H]

COG id: COG0450

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI5802974, Length=173, Percent_Identity=46.242774566474, Blast_Score=163, Evalue=8e-41,
Organism=Homo sapiens, GI32483377, Length=173, Percent_Identity=46.242774566474, Blast_Score=163, Evalue=9e-41,
Organism=Homo sapiens, GI32189392, Length=175, Percent_Identity=42.2857142857143, Blast_Score=149, Evalue=2e-36,
Organism=Homo sapiens, GI4505591, Length=175, Percent_Identity=43.4285714285714, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI32455266, Length=175, Percent_Identity=43.4285714285714, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI32455264, Length=175, Percent_Identity=43.4285714285714, Blast_Score=148, Evalue=3e-36,
Organism=Homo sapiens, GI5453549, Length=180, Percent_Identity=40, Blast_Score=137, Evalue=8e-33,
Organism=Homo sapiens, GI33188454, Length=74, Percent_Identity=48.6486486486487, Blast_Score=87, Evalue=1e-17,
Organism=Escherichia coli, GI1786822, Length=187, Percent_Identity=71.1229946524064, Blast_Score=294, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI17554494, Length=177, Percent_Identity=41.2429378531073, Blast_Score=144, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI32565831, Length=174, Percent_Identity=40.8045977011494, Blast_Score=143, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI193204376, Length=174, Percent_Identity=40.8045977011494, Blast_Score=143, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI25153706, Length=164, Percent_Identity=28.6585365853659, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6320661, Length=181, Percent_Identity=34.8066298342541, Blast_Score=120, Evalue=9e-29,
Organism=Saccharomyces cerevisiae, GI6323613, Length=175, Percent_Identity=36, Blast_Score=118, Evalue=6e-28,
Organism=Saccharomyces cerevisiae, GI6319407, Length=163, Percent_Identity=30.6748466257669, Blast_Score=80, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17738015, Length=177, Percent_Identity=38.4180790960452, Blast_Score=145, Evalue=2e-35,
Organism=Drosophila melanogaster, GI21357347, Length=191, Percent_Identity=36.6492146596859, Blast_Score=141, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24656348, Length=182, Percent_Identity=39.010989010989, Blast_Score=141, Evalue=3e-34,
Organism=Drosophila melanogaster, GI17864676, Length=182, Percent_Identity=39.010989010989, Blast_Score=141, Evalue=3e-34,
Organism=Drosophila melanogaster, GI17157991, Length=170, Percent_Identity=40.5882352941176, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24641739, Length=170, Percent_Identity=40.5882352941176, Blast_Score=139, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24581278, Length=154, Percent_Identity=34.4155844155844, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24652436, Length=163, Percent_Identity=28.8343558282209, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI17975518, Length=158, Percent_Identity=28.4810126582279, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24652434, Length=158, Percent_Identity=28.4810126582279, Blast_Score=69, Evalue=2e-12,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2250 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 6040 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1580 Molecules/Cell In: Stationary-Phase

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017559
- InterPro:   IPR019479
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10417 1-cysPrx_C; PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20752; Mature: 20620

Theoretical pI: Translated: 4.40; Mature: 4.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLINTEIKPFQATAYQNGQFIDISEADLKGKWSVVFFYPADFTFVCPTELEDLADQYAE
CCCCCCCCCCEEEEEECCCCEEEECCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKLGVDIYSVSTDTHFTHKAWHDTSDAIGKIQYAMIGDPTWTISKNFEVLIEAEGLADR
HHHHCEEEEEEECCCCEEECCCCCCCCHHCEEEEEEECCCEEEEECCEEEEEEECCCCCC
GTFVIDPEGKIQIVEINAGGIGRDAQELLRKVKAAVYVYNHPGEVCPAKWKEGDATLAPS
CCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCEEECCC
IDLVGKI
EEEEECC
>Mature Secondary Structure 
SLINTEIKPFQATAYQNGQFIDISEADLKGKWSVVFFYPADFTFVCPTELEDLADQYAE
CCCCCCCCCEEEEEECCCCEEEECCCCCCCEEEEEEEECCCEEEECCCHHHHHHHHHHH
FQKLGVDIYSVSTDTHFTHKAWHDTSDAIGKIQYAMIGDPTWTISKNFEVLIEAEGLADR
HHHHCEEEEEEECCCCEEECCCCCCCCHHCEEEEEEECCCEEEEECCEEEEEEECCCCCC
GTFVIDPEGKIQIVEINAGGIGRDAQELLRKVKAAVYVYNHPGEVCPAKWKEGDATLAPS
CCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHEEEEEECCCCCCCCCCCCCCCEEECCC
IDLVGKI
EEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]