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The map label for this gene is corA [H]

Identifier: 50083659

GI number: 50083659

Start: 404695

End: 405990

Strand: Direct

Name: corA [H]

Synonym: ACIAD0403

Alternate gene names: 50083659

Gene position: 404695-405990 (Clockwise)

Preceding gene: 50083658

Following gene: 50083660

Centisome position: 11.25

GC content: 39.35

Gene sequence:

>1296_bases
GTGAAAGCTGCGTTTTTCATGCAAAGATCATTTAATATCAATTTCATTGATCATGATCTAAGCTGGTTACGCATGCAGGT
TTACTACTTTTACCGACATACTACAGACAACTATATTTTTTTAAGTCGTGAACGCATGACTGATCATGAGCTCATTTTTA
AATGGGCAGACTGTGTACGTGAAGATGTTGTCAATCATGCAGAGCAGTGGCAGAAAAATATTAAAGGACTCACAGATCTG
AGTATCAATGAGTTTCATATTCGAGATATTCTTAATATCGATCATCCATGTGCATTTGACACTATGGAAGATTATGATCT
ACTCATTTTTAGGAAAATTATCACACCCGATGATCAGATCTCCAATAGTGATGTGACAGGTGAGATTCATGAAAGTATTT
TTGGTCTGGCAACCACACCGATTAGCTTTATTATGAGTCAGCATGTGTTGATCAGTATTCGTGAAACAGGAAATAAAGCC
ATTGATCACTATGTAGAACGTTTTGAGCAAATTTTACAGCGTAGTATTGAAGAGCAGAATAAACCGCGTAAACTTCCATC
GACACCGATTGATCTGACCTTACGAATGCTCAATAGCATGATTGATGCTTATCTGGATCTGAGAACACCATTGACTCGTC
GGGTCGAACATTGGCAGCGAGAGCTACTTCAAGGACGCAAGCGATTTAACCAATGGCCCCAATTATTTCAGGAAAATATG
GCGTTTCAGCAAGTCGAAAATTTATGTGAAGAGCAGATTGAAACCTTACAAGAACTACGTGATGAACTGGTTGAAAATTA
CCATCATCTAATGGGCGAACATGCTGCTGAGTCTCCAGATTTACTCTTAGTTCGAATGAATGATCTGGGGAGTCATATTG
AGCGAACACAGAAACATACCTCCAGATTACGAGCTGCGATTCAGTCAGCCATCGATTTACATTTTAATGCGATTGCCAAT
CAAACCAACGAAAACATGCGTATTTTGGCCATCATTACCGCAGTCTTTGCACCTTTAACGCTATTAACGGGGGTGTATGG
TATGAATTTTGAGTTCATTCCAGGCCTCAAATCTCCAGAGGGATTCTGGATGATGTTGGCGGCGATGCTATTGAGCACGG
TCTTACTTTTATATTATTTTTATCGACAACATTTGGTCGGGCGAGGTGAGAAAAGTGTCATTGAGATGCTGGCACAACAG
AAACACCAGCGGAATGTTAATCTGTTCTGGTTTCTAGATTATGAACCCATTAAACAAACGCTTAAAGAAGTTGAAAAGAT
CACACGATTTAAATAA

Upstream 100 bases:

>100_bases
CTTAAAGGTCTGTATCGAGATATGAATAATTCCGAACCTATAAATTAAATTGTCTTTGCAAAATCAAAGAAAGTGAATTG
AATGTTTATTTAGAAATTTT

Downstream 100 bases:

>100_bases
GCGTCCAAATTGATACGATCACAGACTTCACATTGTGAAAGTGCTAGGCTAAACTCGACAGATAGGAGATGACATTCCTC
CTCGCAAAAACCGCCGTTCT

Product: magnesium Mg(2+)/cobalt Co(2+) transport protein

Products: Ni2; [Cytoplasm]; Co; 2 [Cytoplasm]; Mg (II) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MKAAFFMQRSFNINFIDHDLSWLRMQVYYFYRHTTDNYIFLSRERMTDHELIFKWADCVREDVVNHAEQWQKNIKGLTDL
SINEFHIRDILNIDHPCAFDTMEDYDLLIFRKIITPDDQISNSDVTGEIHESIFGLATTPISFIMSQHVLISIRETGNKA
IDHYVERFEQILQRSIEEQNKPRKLPSTPIDLTLRMLNSMIDAYLDLRTPLTRRVEHWQRELLQGRKRFNQWPQLFQENM
AFQQVENLCEEQIETLQELRDELVENYHHLMGEHAAESPDLLLVRMNDLGSHIERTQKHTSRLRAAIQSAIDLHFNAIAN
QTNENMRILAIITAVFAPLTLLTGVYGMNFEFIPGLKSPEGFWMMLAAMLLSTVLLLYYFYRQHLVGRGEKSVIEMLAQQ
KHQRNVNLFWFLDYEPIKQTLKEVEKITRFK

Sequences:

>Translated_431_residues
MKAAFFMQRSFNINFIDHDLSWLRMQVYYFYRHTTDNYIFLSRERMTDHELIFKWADCVREDVVNHAEQWQKNIKGLTDL
SINEFHIRDILNIDHPCAFDTMEDYDLLIFRKIITPDDQISNSDVTGEIHESIFGLATTPISFIMSQHVLISIRETGNKA
IDHYVERFEQILQRSIEEQNKPRKLPSTPIDLTLRMLNSMIDAYLDLRTPLTRRVEHWQRELLQGRKRFNQWPQLFQENM
AFQQVENLCEEQIETLQELRDELVENYHHLMGEHAAESPDLLLVRMNDLGSHIERTQKHTSRLRAAIQSAIDLHFNAIAN
QTNENMRILAIITAVFAPLTLLTGVYGMNFEFIPGLKSPEGFWMMLAAMLLSTVLLLYYFYRQHLVGRGEKSVIEMLAQQ
KHQRNVNLFWFLDYEPIKQTLKEVEKITRFK
>Mature_431_residues
MKAAFFMQRSFNINFIDHDLSWLRMQVYYFYRHTTDNYIFLSRERMTDHELIFKWADCVREDVVNHAEQWQKNIKGLTDL
SINEFHIRDILNIDHPCAFDTMEDYDLLIFRKIITPDDQISNSDVTGEIHESIFGLATTPISFIMSQHVLISIRETGNKA
IDHYVERFEQILQRSIEEQNKPRKLPSTPIDLTLRMLNSMIDAYLDLRTPLTRRVEHWQRELLQGRKRFNQWPQLFQENM
AFQQVENLCEEQIETLQELRDELVENYHHLMGEHAAESPDLLLVRMNDLGSHIERTQKHTSRLRAAIQSAIDLHFNAIAN
QTNENMRILAIITAVFAPLTLLTGVYGMNFEFIPGLKSPEGFWMMLAAMLLSTVLLLYYFYRQHLVGRGEKSVIEMLAQQ
KHQRNVNLFWFLDYEPIKQTLKEVEKITRFK

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 51086; Mature: 51086

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAFFMQRSFNINFIDHDLSWLRMQVYYFYRHTTDNYIFLSRERMTDHELIFKWADCVR
CCCHHHHHHCCCCEEECCCHHHHHHHHHHHHEECCCCEEEEECCCCCHHHHHHHHHHHHH
EDVVNHAEQWQKNIKGLTDLSINEFHIRDILNIDHPCAFDTMEDYDLLIFRKIITPDDQI
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
SNSDVTGEIHESIFGLATTPISFIMSQHVLISIRETGNKAIDHYVERFEQILQRSIEEQN
CCCCCCHHHHHHHHHHHHHHHHHHHHCHHEEEEHHHCCHHHHHHHHHHHHHHHHHHHHCC
KPRKLPSTPIDLTLRMLNSMIDAYLDLRTPLTRRVEHWQRELLQGRKRFNQWPQLFQENM
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFQQVENLCEEQIETLQELRDELVENYHHLMGEHAAESPDLLLVRMNDLGSHIERTQKHT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHH
SRLRAAIQSAIDLHFNAIANQTNENMRILAIITAVFAPLTLLTGVYGMNFEFIPGLKSPE
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC
GFWMMLAAMLLSTVLLLYYFYRQHLVGRGEKSVIEMLAQQKHQRNVNLFWFLDYEPIKQT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHH
LKEVEKITRFK
HHHHHHHHCCC
>Mature Secondary Structure
MKAAFFMQRSFNINFIDHDLSWLRMQVYYFYRHTTDNYIFLSRERMTDHELIFKWADCVR
CCCHHHHHHCCCCEEECCCHHHHHHHHHHHHEECCCCEEEEECCCCCHHHHHHHHHHHHH
EDVVNHAEQWQKNIKGLTDLSINEFHIRDILNIDHPCAFDTMEDYDLLIFRKIITPDDQI
HHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHCCCCCCC
SNSDVTGEIHESIFGLATTPISFIMSQHVLISIRETGNKAIDHYVERFEQILQRSIEEQN
CCCCCCHHHHHHHHHHHHHHHHHHHHCHHEEEEHHHCCHHHHHHHHHHHHHHHHHHHHCC
KPRKLPSTPIDLTLRMLNSMIDAYLDLRTPLTRRVEHWQRELLQGRKRFNQWPQLFQENM
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFQQVENLCEEQIETLQELRDELVENYHHLMGEHAAESPDLLLVRMNDLGSHIERTQKHT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHH
SRLRAAIQSAIDLHFNAIANQTNENMRILAIITAVFAPLTLLTGVYGMNFEFIPGLKSPE
HHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC
GFWMMLAAMLLSTVLLLYYFYRQHLVGRGEKSVIEMLAQQKHQRNVNLFWFLDYEPIKQT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHH
LKEVEKITRFK
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Ni2; [Periplasm]; Co; 2 [Periplasm]; Mg (II) [Periplasm] [C]

Specific reaction: Ni2+ [Periplasm] = Ni2+ [Cytoplasm] Co+2 [Periplasm] = Co+2 [Cytoplasm] Mg (II) [Periplasm] = Mg (II) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]