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The map label for this gene is dsbC [H]

Identifier: 50083542

GI number: 50083542

Start: 265546

End: 266358

Strand: Reverse

Name: dsbC [H]

Synonym: ACIAD0265

Alternate gene names: 50083542

Gene position: 266358-265546 (Counterclockwise)

Preceding gene: 50083543

Following gene: 228913484

Centisome position: 7.4

GC content: 41.45

Gene sequence:

>813_bases
ATGACGTTTACCCGTTCGCATCTTCTTATCGCCTGCGCTTTGGCTGGCAGTTTCGCTCTATCTGCATGTTCTAAGCAGGA
TCAATCTGCTAATCAAGATACGCTTACAGCCAATACTCCTGCTACAGGCGAAGCTTCAACTTTAAGTGAACGAAATGCGC
AACAACGTTTAATTTCAACTTTGCAACAGCATCTTAAAACAGCAAATATCAATGCCAAGATTGTGAATGTTCAAGCTACT
GAAGTTCCCAATTTATATTGGGTGAGTTTGGAAGGTATGCCCTCTATTTATGCAACGAGTGATGGAAAGTATATTATTCA
GGGGGATGTCATTCGTTTGGGCGACAAACAATTGGTCAGTGTCGGTGATGCATTACAAGCCACCGAAAACAAAAAGCTCT
TTGCAGCCTTAAAAAAAGAAGACTTGATTGTTTATCCAGCTAAAGACGGCAAGGCAAAACATGTCATCTACGTATTTACA
GATGCAAGCTGTCCATATTGTCATAAACTGCATGAACATCTTGATGAAATTACCGCCAAAGGTATTGAAGTTCGTTATAT
TGCTTGGCCACGTGGTGAGCAATTTATGCCAACCATGGAAGCGGTCTGGTGTAGTCAGGATCGTAAAGCTGCCTTTACGC
AGGCCGTGCAAGGACAACCTGTACAAGCAGCTCAATGTAAAAACCCAGTACGTGAACAATATCAGCTTGGTTTAAATATT
GGTGTAAATGGTACACCTGCAATTTACAACACCAATGGCGAATACTTAGGTGGATATTTGACACCTGATGAACTGGTAAA
ACGCTTGAAATAA

Upstream 100 bases:

>100_bases
TTTTTCTAGTTACAGTTGGCATCGAATAATTAACATCATTTGAGTATTTTTTTGATATTCTTATCGGCTTGAATAACAAA
TGAAATGAAAAGGGTTGTTT

Downstream 100 bases:

>100_bases
GTTGTTTTATCATTCAAACAATAATTAAAAACCTTGTTTAAACCAAAAAGGTCTTGACTAAAAATTAAATGCGTTGGCAA
TTGTTTATGGAATTGCCAAC

Product: thiol:disulfide interchange protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MTFTRSHLLIACALAGSFALSACSKQDQSANQDTLTANTPATGEASTLSERNAQQRLISTLQQHLKTANINAKIVNVQAT
EVPNLYWVSLEGMPSIYATSDGKYIIQGDVIRLGDKQLVSVGDALQATENKKLFAALKKEDLIVYPAKDGKAKHVIYVFT
DASCPYCHKLHEHLDEITAKGIEVRYIAWPRGEQFMPTMEAVWCSQDRKAAFTQAVQGQPVQAAQCKNPVREQYQLGLNI
GVNGTPAIYNTNGEYLGGYLTPDELVKRLK

Sequences:

>Translated_270_residues
MTFTRSHLLIACALAGSFALSACSKQDQSANQDTLTANTPATGEASTLSERNAQQRLISTLQQHLKTANINAKIVNVQAT
EVPNLYWVSLEGMPSIYATSDGKYIIQGDVIRLGDKQLVSVGDALQATENKKLFAALKKEDLIVYPAKDGKAKHVIYVFT
DASCPYCHKLHEHLDEITAKGIEVRYIAWPRGEQFMPTMEAVWCSQDRKAAFTQAVQGQPVQAAQCKNPVREQYQLGLNI
GVNGTPAIYNTNGEYLGGYLTPDELVKRLK
>Mature_269_residues
TFTRSHLLIACALAGSFALSACSKQDQSANQDTLTANTPATGEASTLSERNAQQRLISTLQQHLKTANINAKIVNVQATE
VPNLYWVSLEGMPSIYATSDGKYIIQGDVIRLGDKQLVSVGDALQATENKKLFAALKKEDLIVYPAKDGKAKHVIYVFTD
ASCPYCHKLHEHLDEITAKGIEVRYIAWPRGEQFMPTMEAVWCSQDRKAAFTQAVQGQPVQAAQCKNPVREQYQLGLNIG
VNGTPAIYNTNGEYLGGYLTPDELVKRLK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process. DsbC is reoxidized by a yet uncharacterized protein. Also acts as a disulfide isomerase [H]

COG id: COG1651

COG function: function code O; Protein-disulfide isomerase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioredoxin family. DsbC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789260, Length=214, Percent_Identity=37.8504672897196, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: 100 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018950
- InterPro:   IPR009094
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF10411 DsbC_N [H]

EC number: 5.3.4.1

Molecular weight: Translated: 29691; Mature: 29560

Theoretical pI: Translated: 7.83; Mature: 7.83

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFTRSHLLIACALAGSFALSACSKQDQSANQDTLTANTPATGEASTLSERNAQQRLIST
CCCCHHHHEEHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHH
LQQHLKTANINAKIVNVQATEVPNLYWVSLEGMPSIYATSDGKYIIQGDVIRLGDKQLVS
HHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCCCEEEECCCCEEEECCEEEECCHHHHH
VGDALQATENKKLFAALKKEDLIVYPAKDGKAKHVIYVFTDASCPYCHKLHEHLDEITAK
HHHHHHHCCCCCEEEEECCCCEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHC
GIEVRYIAWPRGEQFMPTMEAVWCSQDRKAAFTQAVQGQPVQAAQCKNPVREQYQLGLNI
CEEEEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHCCEEE
GVNGTPAIYNTNGEYLGGYLTPDELVKRLK
CCCCCCEEECCCCCEECCEECHHHHHHHCC
>Mature Secondary Structure 
TFTRSHLLIACALAGSFALSACSKQDQSANQDTLTANTPATGEASTLSERNAQQRLIST
CCCHHHHEEHHHHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHH
LQQHLKTANINAKIVNVQATEVPNLYWVSLEGMPSIYATSDGKYIIQGDVIRLGDKQLVS
HHHHHHHCCCCEEEEEEEECCCCCEEEEEECCCCCEEEECCCCEEEECCEEEECCHHHHH
VGDALQATENKKLFAALKKEDLIVYPAKDGKAKHVIYVFTDASCPYCHKLHEHLDEITAK
HHHHHHHCCCCCEEEEECCCCEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHC
GIEVRYIAWPRGEQFMPTMEAVWCSQDRKAAFTQAVQGQPVQAAQCKNPVREQYQLGLNI
CEEEEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCHHHHCCHHHHHHHCCEEE
GVNGTPAIYNTNGEYLGGYLTPDELVKRLK
CCCCCCEEECCCCCEECCEECHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11248100 [H]