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The map label for this gene is thrC [H]

Identifier: 50083540

GI number: 50083540

Start: 262869

End: 264008

Strand: Reverse

Name: thrC [H]

Synonym: ACIAD0263

Alternate gene names: 50083540

Gene position: 264008-262869 (Counterclockwise)

Preceding gene: 228913484

Following gene: 50083538

Centisome position: 7.34

GC content: 44.82

Gene sequence:

>1140_bases
ATGTCTAATGCCAATCGTTATACCGGTCTCGTAGATCGTTATCGTGACCGCTTGCCAGTTTCTGCAACGACACGAGCTAT
TTCTTTAGGTGAAGGAAATACTCCACTGATTAAACTAGAGAATATTCCACGTATCATTGGCAAAGATGTCGAAATTTATG
TCAAGTATGAAGGTTTGAACCCAACAGGTTCATTTAAAGACCGTGGTATGACTATGGCAGTCACCAAAGCCGTTGAAGAA
GGTTCAAAAGCGATTATCTGTGCATCGACAGGCAATACCTCGGCTGCCGCTGCTGCCTATGCAGCACGTGCAGGCATCAA
AGCGTTTGTTTTGATTCCTGAAGGTAAAATTGCCATGGGTAAAATGGCGCAAGCCATGATGTATGGCGCAATCACTATGC
AAATCCGCGGTAACTTCGATGATGGTATGCGTCTAGTAAAAGAAGTTGCCGATCAAGCGCCTGTCACCATTGTTAACTCA
ATTAATCCGTATCGTTTGCAAGGTCAAAAAACCATTGCTTACGAAATCGTGGAAGCTTTAGGTCGTGCGCCTGATTATCA
CTGCTTACCCGTGGGTAATGCAGGTAATATCACGGCACACTGGATGGGTTATACCGAAGCAGTCGCTAACCAGCCAGCAG
ATCAATTTGAGCAAGTGATTTATGATGCCGCTACAGACCAGTTTACTGGTCCTAAACCTGAAGGCTTACCAACGATGGTC
GGTTATCAGGCAGCAGGTGCAGCACCATTCTTACGTGGTGCACCAGTGGAGCAACCAGAAACTGTTGCAACTGCGATTCG
TATTGGTAATCCACAAAGCTGGAACCACGCTAAAGCCGTTGTACGTGACTCTCAAGGCTGGTTTGATGAACTTCAAGATA
GCGAGATTCTAGAAGCTCAACGTTTACTCTCTATGTACGAAGGTGTATTTGTAGAACCTGCTTCTGCAGCGTCTATCGGT
GGTGCAATCCGTGACATTAAAGCGGGCAAAATTGCTGAAGGTTCTGTGATTGTATGTACAGTGACAGGAAATGGCTTAAA
AGATCCAGATACCGCCATCAAACAATGTGCTGATGCAGTCATGCTATCCATTGATGCCACAATGAATCAGGTAAAAGATT
CGATTCTTTCTAATATGTAA

Upstream 100 bases:

>100_bases
CGAAATTGTGCGAATTCGTTTAGAATCGCTTGATAGTTAATCGGGTGGAGAGGGTCTTCCCTCTCGCCAGCTCTACCTTA
CTCTTGGAACATACATCATC

Downstream 100 bases:

>100_bases
GAATTAATTTTCCCATTAAAAAAACCAGTTGCTTGCAACTGGTTTTTTTATATCTAGATTTTTATGACATCTAACTTGAT
ATTGTAGATCGTCTTAAATT

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 379; Mature: 378

Protein sequence:

>379_residues
MSNANRYTGLVDRYRDRLPVSATTRAISLGEGNTPLIKLENIPRIIGKDVEIYVKYEGLNPTGSFKDRGMTMAVTKAVEE
GSKAIICASTGNTSAAAAAYAARAGIKAFVLIPEGKIAMGKMAQAMMYGAITMQIRGNFDDGMRLVKEVADQAPVTIVNS
INPYRLQGQKTIAYEIVEALGRAPDYHCLPVGNAGNITAHWMGYTEAVANQPADQFEQVIYDAATDQFTGPKPEGLPTMV
GYQAAGAAPFLRGAPVEQPETVATAIRIGNPQSWNHAKAVVRDSQGWFDELQDSEILEAQRLLSMYEGVFVEPASAASIG
GAIRDIKAGKIAEGSVIVCTVTGNGLKDPDTAIKQCADAVMLSIDATMNQVKDSILSNM

Sequences:

>Translated_379_residues
MSNANRYTGLVDRYRDRLPVSATTRAISLGEGNTPLIKLENIPRIIGKDVEIYVKYEGLNPTGSFKDRGMTMAVTKAVEE
GSKAIICASTGNTSAAAAAYAARAGIKAFVLIPEGKIAMGKMAQAMMYGAITMQIRGNFDDGMRLVKEVADQAPVTIVNS
INPYRLQGQKTIAYEIVEALGRAPDYHCLPVGNAGNITAHWMGYTEAVANQPADQFEQVIYDAATDQFTGPKPEGLPTMV
GYQAAGAAPFLRGAPVEQPETVATAIRIGNPQSWNHAKAVVRDSQGWFDELQDSEILEAQRLLSMYEGVFVEPASAASIG
GAIRDIKAGKIAEGSVIVCTVTGNGLKDPDTAIKQCADAVMLSIDATMNQVKDSILSNM
>Mature_378_residues
SNANRYTGLVDRYRDRLPVSATTRAISLGEGNTPLIKLENIPRIIGKDVEIYVKYEGLNPTGSFKDRGMTMAVTKAVEEG
SKAIICASTGNTSAAAAAYAARAGIKAFVLIPEGKIAMGKMAQAMMYGAITMQIRGNFDDGMRLVKEVADQAPVTIVNSI
NPYRLQGQKTIAYEIVEALGRAPDYHCLPVGNAGNITAHWMGYTEAVANQPADQFEQVIYDAATDQFTGPKPEGLPTMVG
YQAAGAAPFLRGAPVEQPETVATAIRIGNPQSWNHAKAVVRDSQGWFDELQDSEILEAQRLLSMYEGVFVEPASAASIGG
AIRDIKAGKIAEGSVIVCTVTGNGLKDPDTAIKQCADAVMLSIDATMNQVKDSILSNM

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 40470; Mature: 40338

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNANRYTGLVDRYRDRLPVSATTRAISLGEGNTPLIKLENIPRIIGKDVEIYVKYEGLN
CCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCCCHHHCCCEEEEEEEECCC
PTGSFKDRGMTMAVTKAVEEGSKAIICASTGNTSAAAAAYAARAGIKAFVLIPEGKIAMG
CCCCCCCCCEEHEEHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCHHH
KMAQAMMYGAITMQIRGNFDDGMRLVKEVADQAPVTIVNSINPYRLQGQKTIAYEIVEAL
HHHHHHHHEEEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCEEECCCHHHHHHHHHHH
GRAPDYHCLPVGNAGNITAHWMGYTEAVANQPADQFEQVIYDAATDQFTGPKPEGLPTMV
CCCCCCEEEECCCCCCEEEEECCHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHH
GYQAAGAAPFLRGAPVEQPETVATAIRIGNPQSWNHAKAVVRDSQGWFDELQDSEILEAQ
CCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHHCCCCCHHHHHCCHHHHHHH
RLLSMYEGVFVEPASAASIGGAIRDIKAGKIAEGSVIVCTVTGNGLKDPDTAIKQCADAV
HHHHHHCCEEECCCCHHHHCHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
MLSIDATMNQVKDSILSNM
EEHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNANRYTGLVDRYRDRLPVSATTRAISLGEGNTPLIKLENIPRIIGKDVEIYVKYEGLN
CCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEECCCCHHHCCCEEEEEEEECCC
PTGSFKDRGMTMAVTKAVEEGSKAIICASTGNTSAAAAAYAARAGIKAFVLIPEGKIAMG
CCCCCCCCCEEHEEHHHHHCCCCEEEEEECCCCHHHHHHHHHHCCCEEEEEECCCCCHHH
KMAQAMMYGAITMQIRGNFDDGMRLVKEVADQAPVTIVNSINPYRLQGQKTIAYEIVEAL
HHHHHHHHEEEEEEEECCCHHHHHHHHHHHCCCCEEEEECCCCEEECCCHHHHHHHHHHH
GRAPDYHCLPVGNAGNITAHWMGYTEAVANQPADQFEQVIYDAATDQFTGPKPEGLPTMV
CCCCCCEEEECCCCCCEEEEECCHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCHHH
GYQAAGAAPFLRGAPVEQPETVATAIRIGNPQSWNHAKAVVRDSQGWFDELQDSEILEAQ
CCCCCCCCCCCCCCCCCCCHHHEEEEEECCCCCCCHHHHHHCCCCCHHHHHCCHHHHHHH
RLLSMYEGVFVEPASAASIGGAIRDIKAGKIAEGSVIVCTVTGNGLKDPDTAIKQCADAV
HHHHHHCCEEECCCCHHHHCHHHHHCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHH
MLSIDATMNQVKDSILSNM
EEHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]