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The map label for this gene is ecpD [H]

Identifier: 50083409

GI number: 50083409

Start: 121215

End: 121931

Strand: Direct

Name: ecpD [H]

Synonym: ACIAD0120

Alternate gene names: 50083409

Gene position: 121215-121931 (Clockwise)

Preceding gene: 50083408

Following gene: 50083410

Centisome position: 3.37

GC content: 41.42

Gene sequence:

>717_bases
ATGATGTACTGTATGGGCAGTACCTCAATAGTACATTCGAATGTTGTGATGACAGGCACCCGAGTGATTTATCCTGCCGA
GCAGAAAGAGAAGACTTTGCAGTTTAGCAATAATGCTGATCAAAGTTATCTTGTGCAAATCTGGCTGGATAAAGATAATC
CGCAATCGACACCTGAAACAGCAGATGCACCTTTTTTGATCAATCCGCAGGTGTTCCGAATTAATCCCAAACGGGGTCAA
ATGGTTCGGATGGTCTATACAGGTGATGCAATTTTACCTGCAGACAGAGAGTCGGTTTTTTACCTGAATTTTAAGCAAAT
TCCCGCACTCGAGAAAAATAAACTTGATCAAAATATGTTGGTGTTATTGGTTAAGAGTCGAATAAAAGTTTTTTATCGTC
CTAAAACCATCATTGGACCACCAGAAGATAGCTTTAAAACACTGACATATTCACTGGTAAAAGATCAGCATCTCACTTGG
CTAGAAGTCAATAATCCGAGTGGCTACTACGTCACTGCAACTCAGGCGACTGTCAAAGACAATGTATTGCAGGCCAAAGC
CATTGATGTTGGCATGATTCCACCCAAATCAACAGCACGATGGAAACTTGATCAATCACTGGTTCAAGAGGTAGGTACGG
AAGTGACCTTGCGTCTGGTCAATGATTATGGGGCTTATGTAAATCAGCTTATTCAACCCCAACAGCACTCCAATTAA

Upstream 100 bases:

>100_bases
TCCGCCATGTGCTCTGTATAGGATGACATGGCGTTTTTGACAAAATACAAGAAAAGGATAAAACGTGAAAAAAGCATCTA
AATTCTGGTCAAGTGTGCTG

Downstream 100 bases:

>100_bases
GGTAGGCTGATGATGGTCAAGCATAGCCGCCCTTTGTGGGCACATTCATTTTTATCTGTGGTGATTCACTCGTTACTGTT
TCATTCGGGTCAGTTGTATG

Product: pili assembly chaperone, required for type 1 fimbriae

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 238; Mature: 238

Protein sequence:

>238_residues
MMYCMGSTSIVHSNVVMTGTRVIYPAEQKEKTLQFSNNADQSYLVQIWLDKDNPQSTPETADAPFLINPQVFRINPKRGQ
MVRMVYTGDAILPADRESVFYLNFKQIPALEKNKLDQNMLVLLVKSRIKVFYRPKTIIGPPEDSFKTLTYSLVKDQHLTW
LEVNNPSGYYVTATQATVKDNVLQAKAIDVGMIPPKSTARWKLDQSLVQEVGTEVTLRLVNDYGAYVNQLIQPQQHSN

Sequences:

>Translated_238_residues
MMYCMGSTSIVHSNVVMTGTRVIYPAEQKEKTLQFSNNADQSYLVQIWLDKDNPQSTPETADAPFLINPQVFRINPKRGQ
MVRMVYTGDAILPADRESVFYLNFKQIPALEKNKLDQNMLVLLVKSRIKVFYRPKTIIGPPEDSFKTLTYSLVKDQHLTW
LEVNNPSGYYVTATQATVKDNVLQAKAIDVGMIPPKSTARWKLDQSLVQEVGTEVTLRLVNDYGAYVNQLIQPQQHSN
>Mature_238_residues
MMYCMGSTSIVHSNVVMTGTRVIYPAEQKEKTLQFSNNADQSYLVQIWLDKDNPQSTPETADAPFLINPQVFRINPKRGQ
MVRMVYTGDAILPADRESVFYLNFKQIPALEKNKLDQNMLVLLVKSRIKVFYRPKTIIGPPEDSFKTLTYSLVKDQHLTW
LEVNNPSGYYVTATQATVKDNVLQAKAIDVGMIPPKSTARWKLDQSLVQEVGTEVTLRLVNDYGAYVNQLIQPQQHSN

Specific function: Probably mediates assembly of a pilin [H]

COG id: COG3121

COG function: function code NU; P pilus assembly protein, chaperone PapD

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 Ig-like (immunoglobulin-like) domain [H]

Homologues:

Organism=Escherichia coli, GI1786333, Length=226, Percent_Identity=32.7433628318584, Blast_Score=132, Evalue=1e-32,
Organism=Escherichia coli, GI1790771, Length=226, Percent_Identity=32.7433628318584, Blast_Score=128, Evalue=4e-31,
Organism=Escherichia coli, GI1789532, Length=235, Percent_Identity=33.1914893617021, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1788428, Length=185, Percent_Identity=31.3513513513514, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI1786743, Length=224, Percent_Identity=30.3571428571429, Blast_Score=100, Evalue=7e-23,
Organism=Escherichia coli, GI1787171, Length=232, Percent_Identity=28.448275862069, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081806, Length=217, Percent_Identity=25.8064516129032, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786936, Length=209, Percent_Identity=28.2296650717703, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1788677, Length=224, Percent_Identity=31.25, Blast_Score=74, Evalue=6e-15,
Organism=Escherichia coli, GI87082203, Length=177, Percent_Identity=28.8135593220339, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008962
- InterPro:   IPR001829
- InterPro:   IPR016148
- InterPro:   IPR018046
- InterPro:   IPR016147 [H]

Pfam domain/function: PF02753 Pili_assembly_C; PF00345 Pili_assembly_N [H]

EC number: NA

Molecular weight: Translated: 27058; Mature: 27058

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMYCMGSTSIVHSNVVMTGTRVIYPAEQKEKTLQFSNNADQSYLVQIWLDKDNPQSTPET
CEEEECCCCEEECCEEEECCEEEECCCCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCC
ADAPFLINPQVFRINPKRGQMVRMVYTGDAILPADRESVFYLNFKQIPALEKNKLDQNML
CCCCEEECCEEEEECCCCCCEEEEEEECCEECCCCCCEEEEEEHHHCCCCCCCCCCCHHH
VLLVKSRIKVFYRPKTIIGPPEDSFKTLTYSLVKDQHLTWLEVNNPSGYYVTATQATVKD
EEEEECCEEEEECCCEEECCCCCCHHHEEEEEECCCCEEEEEECCCCCEEEEEECCCHHC
NVLQAKAIDVGMIPPKSTARWKLDQSLVQEVGTEVTLRLVNDYGAYVNQLIQPQQHSN
CEEEEEEEEEECCCCCCCCEEEHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MMYCMGSTSIVHSNVVMTGTRVIYPAEQKEKTLQFSNNADQSYLVQIWLDKDNPQSTPET
CEEEECCCCEEECCEEEECCEEEECCCCCCCEEEECCCCCCEEEEEEEEECCCCCCCCCC
ADAPFLINPQVFRINPKRGQMVRMVYTGDAILPADRESVFYLNFKQIPALEKNKLDQNML
CCCCEEECCEEEEECCCCCCEEEEEEECCEECCCCCCEEEEEEHHHCCCCCCCCCCCHHH
VLLVKSRIKVFYRPKTIIGPPEDSFKTLTYSLVKDQHLTWLEVNNPSGYYVTATQATVKD
EEEEECCEEEEECCCEEECCCCCCHHHEEEEEECCCCEEEEEECCCCCEEEEEECCCHHC
NVLQAKAIDVGMIPPKSTARWKLDQSLVQEVGTEVTLRLVNDYGAYVNQLIQPQQHSN
CEEEEEEEEEECCCCCCCCEEEHHHHHHHHCCCEEEEEEHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8102362; 8202364; 9278503 [H]