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The map label for this gene is ubiG

Identifier: 50083338

GI number: 50083338

Start: 48537

End: 49253

Strand: Reverse

Name: ubiG

Synonym: ACIAD0044

Alternate gene names: 50083338

Gene position: 49253-48537 (Counterclockwise)

Preceding gene: 50083340

Following gene: 50083337

Centisome position: 1.37

GC content: 45.05

Gene sequence:

>717_bases
ATGTCACAACTGAATGTTGATCCACAGGAAATCGCAAAATTTGAAGCACTTGCAGCCAAATGGTGGGATCAGCATTCTGA
ATTTCGCCCACTTCACCAAATTAATCCTTTACGTTTAAACTGGATTGATGAACATGCAGGTGGCCTTGCGGGCAAGAAAG
TACTGGATGTCGGTTGTGGTGGCGGGATTTTGGCTGAAAGTATGGCACGTCGCGGTGCAGATGTACTCGGAATCGATATG
GGTGAGGCACCGCTGAATGTAGCACGTTTACATGCAGAGCAAGAACAAGTCGCAAATATCGAATATCGTCAGATTCCAGT
TGAAGAACTTGCTCAAGAGCAAGCAGGCCAATATGACATTGTGACCTGTATGGAAATGATGGAGCATGTTCCAGATCCTG
CATCAATCATCAAAGCCTGTCAGACTCTGGTCAAACCAGGTGGGCATGTGTTTTTCTCGACCATTAACCGTAACCCAAAA
TCTTACCTATTTGCGATCATTGGTGCCGAATACGTTCTGCGTTTACTGCCAAAAGGAACTCACGATTACCACAAATTTAT
TCGCCCGTCAGAGATGGCACACGATATTCGTGAAGCAGGTCTTAAGCTTAAAGATATGACGGGTTTGCACTACAATCCAT
TGACCAAACACTATTGGCTGGCGCCAAATGTCGATGTCAATTACATGGTGCATACCCTCAAAGAAGGTCAATCATGA

Upstream 100 bases:

>100_bases
TGTGAAGATTTTTTCTGAATTTATCGCTTTTTCTGGAATTACCGCTACACTAAACAGCAAATTAAACGCATTAAAATCAT
CTAAATTTGAGGCCATACCC

Downstream 100 bases:

>100_bases
AAGCAGTTTTATTTGACCTTGATGGAACCTTAATTGATACGGCTGCGGACTTTATTCGCATCATTCAAGAAATGTGTCGT
GAAGAACAGCGCGAAGTGGT

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase

Number of amino acids: Translated: 238; Mature: 237

Protein sequence:

>238_residues
MSQLNVDPQEIAKFEALAAKWWDQHSEFRPLHQINPLRLNWIDEHAGGLAGKKVLDVGCGGGILAESMARRGADVLGIDM
GEAPLNVARLHAEQEQVANIEYRQIPVEELAQEQAGQYDIVTCMEMMEHVPDPASIIKACQTLVKPGGHVFFSTINRNPK
SYLFAIIGAEYVLRLLPKGTHDYHKFIRPSEMAHDIREAGLKLKDMTGLHYNPLTKHYWLAPNVDVNYMVHTLKEGQS

Sequences:

>Translated_238_residues
MSQLNVDPQEIAKFEALAAKWWDQHSEFRPLHQINPLRLNWIDEHAGGLAGKKVLDVGCGGGILAESMARRGADVLGIDM
GEAPLNVARLHAEQEQVANIEYRQIPVEELAQEQAGQYDIVTCMEMMEHVPDPASIIKACQTLVKPGGHVFFSTINRNPK
SYLFAIIGAEYVLRLLPKGTHDYHKFIRPSEMAHDIREAGLKLKDMTGLHYNPLTKHYWLAPNVDVNYMVHTLKEGQS
>Mature_237_residues
SQLNVDPQEIAKFEALAAKWWDQHSEFRPLHQINPLRLNWIDEHAGGLAGKKVLDVGCGGGILAESMARRGADVLGIDMG
EAPLNVARLHAEQEQVANIEYRQIPVEELAQEQAGQYDIVTCMEMMEHVPDPASIIKACQTLVKPGGHVFFSTINRNPKS
YLFAIIGAEYVLRLLPKGTHDYHKFIRPSEMAHDIREAGLKLKDMTGLHYNPLTKHYWLAPNVDVNYMVHTLKEGQS

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family

Homologues:

Organism=Homo sapiens, GI118600965, Length=246, Percent_Identity=36.9918699186992, Blast_Score=182, Evalue=3e-46,
Organism=Escherichia coli, GI1788564, Length=228, Percent_Identity=64.0350877192982, Blast_Score=313, Evalue=5e-87,
Organism=Caenorhabditis elegans, GI115533050, Length=240, Percent_Identity=35, Blast_Score=142, Evalue=1e-34,
Organism=Saccharomyces cerevisiae, GI6324476, Length=254, Percent_Identity=32.6771653543307, Blast_Score=124, Evalue=1e-29,
Organism=Drosophila melanogaster, GI281365311, Length=246, Percent_Identity=31.3008130081301, Blast_Score=140, Evalue=8e-34,
Organism=Drosophila melanogaster, GI24585589, Length=198, Percent_Identity=35.8585858585859, Blast_Score=136, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIG_ACIAD (Q6FFY1)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_044848.1
- ProteinModelPortal:   Q6FFY1
- SMR:   Q6FFY1
- STRING:   Q6FFY1
- GeneID:   2880804
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0044
- NMPDR:   fig|62977.3.peg.1168
- eggNOG:   COG2227
- HOGENOM:   HBG738842
- OMA:   DHAEIAK
- PhylomeDB:   Q6FFY1
- ProtClustDB:   PRK05134
- BioCyc:   ASP62977:ACIAD0044-MONOMER
- HAMAP:   MF_00472
- InterPro:   IPR013216
- InterPro:   IPR010233
- TIGRFAMs:   TIGR01983

Pfam domain/function: PF08241 Methyltransf_11

EC number: =2.1.1.64

Molecular weight: Translated: 26744; Mature: 26613

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQLNVDPQEIAKFEALAAKWWDQHSEFRPLHQINPLRLNWIDEHAGGLAGKKVLDVGCG
CCCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCEEEEEEHHHCCCCCCCCEEEECCC
GGILAESMARRGADVLGIDMGEAPLNVARLHAEQEQVANIEYRQIPVEELAQEQAGQYDI
CHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHCCCCHH
VTCMEMMEHVPDPASIIKACQTLVKPGGHVFFSTINRNPKSYLFAIIGAEYVLRLLPKGT
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
HDYHKFIRPSEMAHDIREAGLKLKDMTGLHYNPLTKHYWLAPNVDVNYMVHTLKEGQS
HHHHHHCCHHHHHHHHHHHCCEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCC
>Mature Secondary Structure 
SQLNVDPQEIAKFEALAAKWWDQHSEFRPLHQINPLRLNWIDEHAGGLAGKKVLDVGCG
CCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHCCCCEEEEEEHHHCCCCCCCCEEEECCC
GGILAESMARRGADVLGIDMGEAPLNVARLHAEQEQVANIEYRQIPVEELAQEQAGQYDI
CHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHCCCCHH
VTCMEMMEHVPDPASIIKACQTLVKPGGHVFFSTINRNPKSYLFAIIGAEYVLRLLPKGT
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCC
HDYHKFIRPSEMAHDIREAGLKLKDMTGLHYNPLTKHYWLAPNVDVNYMVHTLKEGQS
HHHHHHCCHHHHHHHHHHHCCEEECCCCCCCCCCCCEEEECCCCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA