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The map label for this gene is rutG [H]

Identifier: 50083326

GI number: 50083326

Start: 36899

End: 38263

Strand: Direct

Name: rutG [H]

Synonym: ACIAD0031

Alternate gene names: 50083326

Gene position: 36899-38263 (Clockwise)

Preceding gene: 50083325

Following gene: 50083327

Centisome position: 1.03

GC content: 46.45

Gene sequence:

>1365_bases
ATGTCGAGTCAAGAACCGTGGTTTGCCAAATTTAAGCCTTATCAAGGCGATCTGGAACATCATCCTGTCCAGATCGATGA
ATATCTTCCCGCAGGCAAAAGTATTGTGTTAGGGCTACAACATGCTTTTGCCATGTTTGGCGCAACTGTACTGGCACCGT
TATTGATGGGCTTTGATCCCAATCTGACGATTTTTATAACTGGGTTTGGTACCATTTTATTCTTTTTAATTACAGGTGGT
CGTTTACCCAGCTATCTGGGTTCAAGTTTTGCCTTTATTGCAGCAGTCGCGGCGGCAACGGGCTATAACGGGGTGGGGAC
CAATCCAAATCTGGCACTAGCGCTGGGTGGAACGGTGGTCTGTGGTGTGATTTATGCTGCCATCGGTCTGATCGTGATGC
GTACAGGAACAGCATGGATTGAAAAATTGATGCCACCGATTGTCACAGGTGCAATTGTCATGATCATTGGCTTGAATCTG
GCTCCTGTGACCATCAAAGGTGTATCTGGAAATGGCTTTGATACATGGATGGCTGTGCTGACGATCTTATGTATCAGTGC
TGTGGCCGTATTTACTCGCGGTATGCTACGTCGATTATTACTTTTAGTGGGACTTTGTGCGGCTTATTTTGCCTATTTTA
TCTTGGCCAATGTATTTGGCTTGGGCAAAGCCATTGATTTTAGTCCGATCGCTCAAGCTGCCTGGTTGGGTATCCCGAAC
TTTCATACCCCTGTTTTTCAAGCCAATGCAATTTTACTCATCGCACCTGTGGCCCTGATTCTGGTAGCAGAAAATCTGGG
ACATTTTAAAGCGGTATCCGCCATGACGGGTCGTAATCTATCGCCTTATATGGGACGTGGTTTCTTTGCAGATGGTGTGT
GTACCACTTTATCTGCCTCAGTGGGTGGTACGGGCATGACCACCTATGCCGAAAATATTGGCGTGATGGCAGTGACCAAA
GTTTATTCGACGACCGTGTTTGTTGTGGCAGGGGTATTTGCAATTTTACTTGGGCTTTCACCTAAGTTTGGCGCAGTGAT
TCATACCATTCCAGTTGCCTTGCTTGGTGGGGCGTCAATTGTGGTGTTTGGCCTGATCACTGTTGCAGGTGCCAAAATCT
GGATTGATCATAAAGTGGATTTTACTCAGAACAGTACGCTGATTATTGCGGCTGTGAGTCTGATTATGGGGGCAGGCAAT
TTTAGTTTACATATTGGAGCGTTTGATTTGGGGGGAATTGGGACTGCGACACTGGCGGCAATTGTACTGAACTTATTGCT
CAATCGTGATTCTGGCAAGCGCAGTCAGCTTGAACCCAATGCACAGCCTGAGAAAATCATTCAGCCTGTCAGCCCTCAAT
CTTAA

Upstream 100 bases:

>100_bases
AACATTGCCAAGGACAAAATGCCTTGATGTATTTTAACCGCAATTATTGCGAACCCCATTGTGTAGCTTAAGTCTCATAT
TGAAATGAGGAGAAATAGCG

Downstream 100 bases:

>100_bases
GGAGACCGTTGTATCATGCGTATCGGATTTATTGGATTAGGGGCCATGGGCTGGCATATGGCAGGCCACTTGACCCAACT
CGATGCCACTGTGATGGTCT

Product: purine permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 453

Protein sequence:

>454_residues
MSSQEPWFAKFKPYQGDLEHHPVQIDEYLPAGKSIVLGLQHAFAMFGATVLAPLLMGFDPNLTIFITGFGTILFFLITGG
RLPSYLGSSFAFIAAVAAATGYNGVGTNPNLALALGGTVVCGVIYAAIGLIVMRTGTAWIEKLMPPIVTGAIVMIIGLNL
APVTIKGVSGNGFDTWMAVLTILCISAVAVFTRGMLRRLLLLVGLCAAYFAYFILANVFGLGKAIDFSPIAQAAWLGIPN
FHTPVFQANAILLIAPVALILVAENLGHFKAVSAMTGRNLSPYMGRGFFADGVCTTLSASVGGTGMTTYAENIGVMAVTK
VYSTTVFVVAGVFAILLGLSPKFGAVIHTIPVALLGGASIVVFGLITVAGAKIWIDHKVDFTQNSTLIIAAVSLIMGAGN
FSLHIGAFDLGGIGTATLAAIVLNLLLNRDSGKRSQLEPNAQPEKIIQPVSPQS

Sequences:

>Translated_454_residues
MSSQEPWFAKFKPYQGDLEHHPVQIDEYLPAGKSIVLGLQHAFAMFGATVLAPLLMGFDPNLTIFITGFGTILFFLITGG
RLPSYLGSSFAFIAAVAAATGYNGVGTNPNLALALGGTVVCGVIYAAIGLIVMRTGTAWIEKLMPPIVTGAIVMIIGLNL
APVTIKGVSGNGFDTWMAVLTILCISAVAVFTRGMLRRLLLLVGLCAAYFAYFILANVFGLGKAIDFSPIAQAAWLGIPN
FHTPVFQANAILLIAPVALILVAENLGHFKAVSAMTGRNLSPYMGRGFFADGVCTTLSASVGGTGMTTYAENIGVMAVTK
VYSTTVFVVAGVFAILLGLSPKFGAVIHTIPVALLGGASIVVFGLITVAGAKIWIDHKVDFTQNSTLIIAAVSLIMGAGN
FSLHIGAFDLGGIGTATLAAIVLNLLLNRDSGKRSQLEPNAQPEKIIQPVSPQS
>Mature_453_residues
SSQEPWFAKFKPYQGDLEHHPVQIDEYLPAGKSIVLGLQHAFAMFGATVLAPLLMGFDPNLTIFITGFGTILFFLITGGR
LPSYLGSSFAFIAAVAAATGYNGVGTNPNLALALGGTVVCGVIYAAIGLIVMRTGTAWIEKLMPPIVTGAIVMIIGLNLA
PVTIKGVSGNGFDTWMAVLTILCISAVAVFTRGMLRRLLLLVGLCAAYFAYFILANVFGLGKAIDFSPIAQAAWLGIPNF
HTPVFQANAILLIAPVALILVAENLGHFKAVSAMTGRNLSPYMGRGFFADGVCTTLSASVGGTGMTTYAENIGVMAVTKV
YSTTVFVVAGVFAILLGLSPKFGAVIHTIPVALLGGASIVVFGLITVAGAKIWIDHKVDFTQNSTLIIAAVSLIMGAGNF
SLHIGAFDLGGIGTATLAAIVLNLLLNRDSGKRSQLEPNAQPEKIIQPVSPQS

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680145, Length=174, Percent_Identity=29.8850574712644, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI44680143, Length=174, Percent_Identity=29.8850574712644, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI87081818, Length=441, Percent_Identity=62.1315192743764, Blast_Score=553, Evalue=1e-158,
Organism=Escherichia coli, GI1788843, Length=431, Percent_Identity=37.3549883990719, Blast_Score=258, Evalue=7e-70,
Organism=Escherichia coli, GI87082181, Length=444, Percent_Identity=28.1531531531532, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87082178, Length=279, Percent_Identity=29.3906810035842, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790087, Length=404, Percent_Identity=25.2475247524752, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17558856, Length=432, Percent_Identity=26.3888888888889, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI17541904, Length=174, Percent_Identity=31.0344827586207, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17542262, Length=172, Percent_Identity=32.5581395348837, Blast_Score=78, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17542260, Length=211, Percent_Identity=29.8578199052133, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71993493, Length=211, Percent_Identity=29.3838862559242, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21356175, Length=206, Percent_Identity=27.6699029126214, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 47436; Mature: 47305

Theoretical pI: Translated: 8.84; Mature: 8.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSQEPWFAKFKPYQGDLEHHPVQIDEYLPAGKSIVLGLQHAFAMFGATVLAPLLMGFDP
CCCCCCCCEECCCCCCCCCCCCEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
NLTIFITGFGTILFFLITGGRLPSYLGSSFAFIAAVAAATGYNGVGTNPNLALALGGTVV
CEEEEEEHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHH
CGVIYAAIGLIVMRTGTAWIEKLMPPIVTGAIVMIIGLNLAPVTIKGVSGNGFDTWMAVL
HHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHH
TILCISAVAVFTRGMLRRLLLLVGLCAAYFAYFILANVFGLGKAIDFSPIAQAAWLGIPN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCC
FHTPVFQANAILLIAPVALILVAENLGHFKAVSAMTGRNLSPYMGRGFFADGVCTTLSAS
CCCCHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHCCCCCCCCHHHHHHHC
VGGTGMTTYAENIGVMAVTKVYSTTVFVVAGVFAILLGLSPKFGAVIHTIPVALLGGASI
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHH
VVFGLITVAGAKIWIDHKVDFTQNSTLIIAAVSLIMGAGNFSLHIGAFDLGGIGTATLAA
HHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECEECCCCCHHHHHH
IVLNLLLNRDSGKRSQLEPNAQPEKIIQPVSPQS
HHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
SSQEPWFAKFKPYQGDLEHHPVQIDEYLPAGKSIVLGLQHAFAMFGATVLAPLLMGFDP
CCCCCCCEECCCCCCCCCCCCEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
NLTIFITGFGTILFFLITGGRLPSYLGSSFAFIAAVAAATGYNGVGTNPNLALALGGTVV
CEEEEEEHHHHHHHHHHCCCCCHHHHCCHHHHHHHHHHHCCCCCCCCCCCEEEEECHHHH
CGVIYAAIGLIVMRTGTAWIEKLMPPIVTGAIVMIIGLNLAPVTIKGVSGNGFDTWMAVL
HHHHHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHH
TILCISAVAVFTRGMLRRLLLLVGLCAAYFAYFILANVFGLGKAIDFSPIAQAAWLGIPN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCC
FHTPVFQANAILLIAPVALILVAENLGHFKAVSAMTGRNLSPYMGRGFFADGVCTTLSAS
CCCCHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHCCCCCCCCHHHHHHHC
VGGTGMTTYAENIGVMAVTKVYSTTVFVVAGVFAILLGLSPKFGAVIHTIPVALLGGASI
CCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCHHH
VVFGLITVAGAKIWIDHKVDFTQNSTLIIAAVSLIMGAGNFSLHIGAFDLGGIGTATLAA
HHHHHHHHHCCEEEEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEECEECCCCCHHHHHH
IVLNLLLNRDSGKRSQLEPNAQPEKIIQPVSPQS
HHHHHHHCCCCCCCCCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]