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The map label for this gene is ileS

Identifier: 50083317

GI number: 50083317

Start: 26764

End: 29601

Strand: Reverse

Name: ileS

Synonym: ACIAD0022

Alternate gene names: 50083317

Gene position: 29601-26764 (Counterclockwise)

Preceding gene: 50083318

Following gene: 50083316

Centisome position: 0.82

GC content: 44.82

Gene sequence:

>2838_bases
ATGAGCGATAAGCAAACTCCTGAAAATGCAGTGGACTATAAAGCCACGCTAAACCTGCCGGGCACCGAATTTGCCATGAA
AGCAAACTTGGCCGTGCGCGAAGTGAAATGGTTAGAAGAGTGGTATGCCGACAACATTTATCAGAAGATTCGTGCATCGC
GTATTGGTAAGAAAAAATATGTTTTACATGATGGTCCTCCTTATGCCAATGGTCAGATCCATTTGGGTCATGCCGTCAAT
AAAGTCTTAAAAGATATTATCGTCAAAAGCCGTGTCATGGACGGTTTTGACGCACCTTATGTGCCTGGCTGGGACTGTCA
TGGTTTACCAATTGAGCTTAAAGTTGAAGAAAAAGTCGGTAAGGTCGGTGTGAAGGTCGATGCCTCAACTTTCCGTAAAG
CGTGTCGTGAGTATGCGTTGAGTCAAGTCGACTTACAGCGTAAAGACTTTATTCGTATGGGCGTATTTGGTGACTGGCAA
GACCCTTACTTGACCATGAACTTTAAGCAAGAAGCCGATATTGTTCGCTCACTTGGTGAGATTCAGAAAGCAGGTCATAT
CGAGCCTGGCTTAAAACCAGTGAACTGGTGTATCGACTGTGGTTCTGCATTGGCAGAAGCAGAAGTTGAATATGAAGATA
AAAAATCCGATGCGATTGATGTCGGTTTTGGCGTGGTTGATCTGAATGATTTAAGTGCCCGTTTAAACGTAGAAGTTCAA
GATCCAACTGATATTGTGATCTGGACGACTACACCTTGGACATTGCCTGCTAACCAAGCGGTTGCTTTGCATGCCGAGAT
TGACTATCAATTGGTACAAGTACAAAGCGATCGTGGTACGCAAAACTTTATCTTGGCCAAAGATCTGGTCGAATCTGCGA
TTGCTCGCTATAAGCTCGAAAATCCAGTGGTATTGGCTGATTTTAAAGGTGCGGTACTTGAATTACTTCAGTTACAGCAT
CCACTCTTGGCAGATCGTCAGGTTCCTGTGATCTTAGGTGAACACGTCATTGCAACTAGTGGTACAGGTGCGGTTCATAC
TGCGCCAGGTCACGGTACTGACGACTATAAAGTGGGTCTGATTTATAACCTTAAAGTCGATAATCCTGTGGGCGGTAATG
GGGTGTATTTACCAACTGCGCCAATTTTCTCGGGTGAGCATATTTATAAAGCCAACCCACAAATCATTGAAGCATTGGGT
GCAACAGGTCGTCTTTGGGCACATCAACCCATTGTACATAGCTATCCACATTGCTGGCGCCATAAAACTCCAATTATTTT
CCGTGCGACACCGCAATGGTTTATCAGCATGGATGCCAAAGGTCTACGTGAATGTGCCCTCAATGCGATTGAAAATGACA
TCAGCTTTGTACCAGACTGGGGTAAAAACCGGATTGAATCGATGATTGAAGGTCGTCCAGACTGGTGTATCTCACGTCAA
CGGACTTGGGGTGTGCCAATTCCATTTTTTGTACACAAAGATACCAACGAACTTCACCCGCGTACCCCTGAGCTGATTGA
AGAAGTTGCTCAGCTCATTGAGCACGAAGGAATCGATGCCTGGTTTAACCGTGAAGCCAAAGACTTCATCGGTGCCGATG
CTGAACACTACAATGCCGTCCGAGATACCCTTGATGTCTGGTTCGACTCTGGTACAACACACTATGCAGTATTACGTCAG
CGTGAAGAATTGACGGATCCAGCAGATTTGTATCTGGAAGGTTCAGATCAGCATCGTGGCTGGTTCCAGTCATCATTGCT
GACATCTATTGCCATCAATGAACGTGCACCATATAAGGGTCTGCTCACACACGGTTTCGTGGTCGATGAAAAAGGCCGCA
AGATGTCTAAATCTTTGGGCAATATCATTACGCCGCAAGACATTATCAAAGATATGGGTGCTGATGGTTTACGTTTTTGG
ATTGCATCTAGTGACTATCGCTATGAAATGACTGCAGGTAAAGAAATTTTCAGTCGTGCGTCAGATGGTTATCGTCGTAT
TCGTAATACCTTGCGTTTCTTGTTGGCGAACCTAAATGGCTTTACACCATCGACGGATGCATTGCCTGTTGATCAACTGA
TCGCATTAGATCAATACATCCTACAACGTGCGGCTGAGGTTCAGAAAACCGTTCAGCAAGCCTATGAAGACATGAACTTC
CATATTGTTTGTAGCGCTTTGACCAACTTCTGTATCAATGACTTGGGCGGTTTCTATCTCGATATTATTAAAGATCGTCA
GTACACCACCAAGGCAGATTCAGCAGCTCGCCATTCAGCACAAACTGCGTTGTATCATTTGGTTCAAGCCTTTGTTCGCT
GGATGAGCCCTATCTTGAGCTTCACTGCACAAGAAGCTTGGCCGTTGATTCCAGAGCAAACCGAGCAATATGTGTTTACT
ACTGAGTGGTACGACATTCCAGTCGCATCGACTGCCAACCTGATTTCAGAAGCAGATTGGCAAACATTAATTAGCGTAAA
ATCAGCAGTAAATAAACAGATTGAAGCGGCACGTAATGCCAAACTGGTGGGTAGTAATCTTTCTGCCAAAGTTGAAATTT
GGGCCAAAGACGAACTTCAAAGCGTATTAAACCAATTGGGTGACGAATTGCGTTTTGTCCTGATTACCTCTCAGGTGAAT
GTTTATCCGTATGCAGAGCAAGGTGAAAGCACTGAAATGGATGGCTTACGCGTGCAAATTTCGGCGGCTGAAGGTGAAAA
ATGTGTACGTTGCTGGCATGTTCTCCCCGATGTAAATACTCATGCAGATCATCCAGGTTTATGCGGTCGTTGCATTATTA
ACGTCACGGGCAGTGGCGAAGTGAGAAAATATGCCTAA

Upstream 100 bases:

>100_bases
GAATTTCGTAAGCAAAATACCCAACGCCCTTTTTAATTTAAAATTTTTGATGTTAAAAACACGTCAGCTTTAACGCTGAT
CGAACTGGAAGACAACTTGC

Downstream 100 bases:

>100_bases
GCTTGAAGCAAAAAAAGGCTTATTCCAGTTTTATCCGCATAATCTAATTTGGCTTGGACTTTCAATCCTTGCCATTATTA
TTGATCAGTGGACAAAATGG

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 945; Mature: 944

Protein sequence:

>945_residues
MSDKQTPENAVDYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANGQIHLGHAVN
KVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDASTFRKACREYALSQVDLQRKDFIRMGVFGDWQ
DPYLTMNFKQEADIVRSLGEIQKAGHIEPGLKPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQ
DPTDIVIWTTTPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKGAVLELLQLQH
PLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPVGGNGVYLPTAPIFSGEHIYKANPQIIEALG
ATGRLWAHQPIVHSYPHCWRHKTPIIFRATPQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQ
RTWGVPIPFFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAVRDTLDVWFDSGTTHYAVLRQ
REELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLTHGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFW
IASSDYRYEMTAGKEIFSRASDGYRRIRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNF
HIVCSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTAQEAWPLIPEQTEQYVFT
TEWYDIPVASTANLISEADWQTLISVKSAVNKQIEAARNAKLVGSNLSAKVEIWAKDELQSVLNQLGDELRFVLITSQVN
VYPYAEQGESTEMDGLRVQISAAEGEKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA

Sequences:

>Translated_945_residues
MSDKQTPENAVDYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANGQIHLGHAVN
KVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDASTFRKACREYALSQVDLQRKDFIRMGVFGDWQ
DPYLTMNFKQEADIVRSLGEIQKAGHIEPGLKPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQ
DPTDIVIWTTTPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKGAVLELLQLQH
PLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPVGGNGVYLPTAPIFSGEHIYKANPQIIEALG
ATGRLWAHQPIVHSYPHCWRHKTPIIFRATPQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQ
RTWGVPIPFFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAVRDTLDVWFDSGTTHYAVLRQ
REELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLTHGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFW
IASSDYRYEMTAGKEIFSRASDGYRRIRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNF
HIVCSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTAQEAWPLIPEQTEQYVFT
TEWYDIPVASTANLISEADWQTLISVKSAVNKQIEAARNAKLVGSNLSAKVEIWAKDELQSVLNQLGDELRFVLITSQVN
VYPYAEQGESTEMDGLRVQISAAEGEKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA
>Mature_944_residues
SDKQTPENAVDYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKYVLHDGPPYANGQIHLGHAVNK
VLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVGKVGVKVDASTFRKACREYALSQVDLQRKDFIRMGVFGDWQD
PYLTMNFKQEADIVRSLGEIQKAGHIEPGLKPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQD
PTDIVIWTTTPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLENPVVLADFKGAVLELLQLQHP
LLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGLIYNLKVDNPVGGNGVYLPTAPIFSGEHIYKANPQIIEALGA
TGRLWAHQPIVHSYPHCWRHKTPIIFRATPQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQR
TWGVPIPFFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAVRDTLDVWFDSGTTHYAVLRQR
EELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKGLLTHGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWI
ASSDYRYEMTAGKEIFSRASDGYRRIRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNFH
IVCSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILSFTAQEAWPLIPEQTEQYVFTT
EWYDIPVASTANLISEADWQTLISVKSAVNKQIEAARNAKLVGSNLSAKVEIWAKDELQSVLNQLGDELRFVLITSQVNV
YPYAEQGESTEMDGLRVQISAAEGEKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily

Homologues:

Organism=Homo sapiens, GI46852147, Length=992, Percent_Identity=35.0806451612903, Blast_Score=550, Evalue=1e-156,
Organism=Homo sapiens, GI94721239, Length=691, Percent_Identity=29.6671490593343, Blast_Score=285, Evalue=1e-76,
Organism=Homo sapiens, GI94721241, Length=691, Percent_Identity=29.6671490593343, Blast_Score=285, Evalue=1e-76,
Organism=Homo sapiens, GI5454158, Length=803, Percent_Identity=24.6575342465753, Blast_Score=191, Evalue=3e-48,
Organism=Homo sapiens, GI268370293, Length=830, Percent_Identity=23.2530120481928, Blast_Score=172, Evalue=1e-42,
Organism=Homo sapiens, GI268370297, Length=830, Percent_Identity=23.2530120481928, Blast_Score=172, Evalue=2e-42,
Organism=Homo sapiens, GI268370295, Length=795, Percent_Identity=23.7735849056604, Blast_Score=169, Evalue=9e-42,
Organism=Escherichia coli, GI2367096, Length=942, Percent_Identity=56.2632696390658, Blast_Score=1088, Evalue=0.0,
Organism=Escherichia coli, GI1790708, Length=801, Percent_Identity=23.2209737827715, Blast_Score=150, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI71980946, Length=959, Percent_Identity=31.2825860271116, Blast_Score=416, Evalue=1e-116,
Organism=Caenorhabditis elegans, GI17541896, Length=802, Percent_Identity=27.8054862842893, Blast_Score=288, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI17510661, Length=791, Percent_Identity=24.905183312263, Blast_Score=206, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI72001587, Length=803, Percent_Identity=24.4084682440847, Blast_Score=165, Evalue=1e-40,
Organism=Saccharomyces cerevisiae, GI6325217, Length=996, Percent_Identity=33.9357429718875, Blast_Score=515, Evalue=1e-146,
Organism=Saccharomyces cerevisiae, GI6319395, Length=788, Percent_Identity=27.9187817258883, Blast_Score=288, Evalue=4e-78,
Organism=Saccharomyces cerevisiae, GI6321531, Length=882, Percent_Identity=23.6961451247166, Blast_Score=179, Evalue=1e-45,
Organism=Drosophila melanogaster, GI281366294, Length=870, Percent_Identity=34.2528735632184, Blast_Score=463, Evalue=1e-130,
Organism=Drosophila melanogaster, GI28574730, Length=812, Percent_Identity=28.9408866995074, Blast_Score=307, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24668547, Length=812, Percent_Identity=28.9408866995074, Blast_Score=307, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24668543, Length=812, Percent_Identity=28.9408866995074, Blast_Score=307, Evalue=2e-83,
Organism=Drosophila melanogaster, GI17864482, Length=926, Percent_Identity=24.2980561555076, Blast_Score=186, Evalue=8e-47,
Organism=Drosophila melanogaster, GI24653289, Length=926, Percent_Identity=24.2980561555076, Blast_Score=186, Evalue=8e-47,
Organism=Drosophila melanogaster, GI21355675, Length=856, Percent_Identity=23.5981308411215, Blast_Score=183, Evalue=5e-46,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_ACIAD (Q6FG02)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_044827.1
- ProteinModelPortal:   Q6FG02
- SMR:   Q6FG02
- STRING:   Q6FG02
- GeneID:   2878563
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD0022
- NMPDR:   fig|62977.3.peg.1087
- eggNOG:   COG0060
- HOGENOM:   HBG577712
- OMA:   KQVLTHG
- PhylomeDB:   Q6FG02
- ProtClustDB:   PRK05743
- BioCyc:   ASP62977:ACIAD0022-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_02002
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- InterPro:   IPR010663
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; PF06827 zf-FPG_IleRS; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 106146; Mature: 106015

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 573-573 BINDING 617-617

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDKQTPENAVDYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKY
CCCCCCCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VLHDGPPYANGQIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVG
EEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHC
KVGVKVDASTFRKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGE
CCCEEECHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCCCCEEEEECCHHHHHHHHHHH
IQKAGHIEPGLKPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQ
HHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECEEEEEECCCCEEEEEEEE
DPTDIVIWTTTPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLE
CCCCEEEEECCCCCCCCCCEEEEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCC
NPVVLADFKGAVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGL
CCEEEECCCHHHHHHHHHCCCHHCCCCCCEEECCEEEEECCCCCEECCCCCCCCCEEEEE
IYNLKVDNPVGGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWR
EEEEEECCCCCCCEEEECCCCCCCCCEEEECCHHHHHHHCCCCCEECCCCHHHCCCHHHC
HKTPIIFRATPQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQ
CCCCEEEEECCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCEECCC
RTWGVPIPFFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAV
CCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHCCCHHHHHHH
RDTLDVWFDSGTTHYAVLRQREELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKG
HHHHHHHCCCCCCHHHHHHHHHHCCCCHHEEEECCCCCCHHHHHHHHHHHHCCCCCCCCC
LLTHGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRA
HHHCCEEECCCCHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCEEEEEHHHHHHHHHH
SDGYRRIRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
HIVCSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILS
EEEHHHHHHHHHHHCCHHEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTAQEAWPLIPEQTEQYVFTTEWYDIPVASTANLISEADWQTLISVKSAVNKQIEAARNA
HHHHHCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KLVGSNLSAKVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPYAEQGESTEMDGLRVQI
EEECCCCCEEEEEEEHHHHHHHHHHCCCCEEEEEEEECEEEEEECCCCCCCCCCCEEEEE
SAAEGEKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA
ECCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure 
SDKQTPENAVDYKATLNLPGTEFAMKANLAVREVKWLEEWYADNIYQKIRASRIGKKKY
CCCCCCCCCCCEEEEECCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
VLHDGPPYANGQIHLGHAVNKVLKDIIVKSRVMDGFDAPYVPGWDCHGLPIELKVEEKVG
EEECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEHHHHC
KVGVKVDASTFRKACREYALSQVDLQRKDFIRMGVFGDWQDPYLTMNFKQEADIVRSLGE
CCCEEECHHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCCCCEEEEECCHHHHHHHHHHH
IQKAGHIEPGLKPVNWCIDCGSALAEAEVEYEDKKSDAIDVGFGVVDLNDLSARLNVEVQ
HHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEECEEEEEECCCCEEEEEEEE
DPTDIVIWTTTPWTLPANQAVALHAEIDYQLVQVQSDRGTQNFILAKDLVESAIARYKLE
CCCCEEEEECCCCCCCCCCEEEEEEECCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCC
NPVVLADFKGAVLELLQLQHPLLADRQVPVILGEHVIATSGTGAVHTAPGHGTDDYKVGL
CCEEEECCCHHHHHHHHHCCCHHCCCCCCEEECCEEEEECCCCCEECCCCCCCCCEEEEE
IYNLKVDNPVGGNGVYLPTAPIFSGEHIYKANPQIIEALGATGRLWAHQPIVHSYPHCWR
EEEEEECCCCCCCEEEECCCCCCCCCEEEECCHHHHHHHCCCCCEECCCCHHHCCCHHHC
HKTPIIFRATPQWFISMDAKGLRECALNAIENDISFVPDWGKNRIESMIEGRPDWCISRQ
CCCCEEEEECCCEEEECCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCEECCC
RTWGVPIPFFVHKDTNELHPRTPELIEEVAQLIEHEGIDAWFNREAKDFIGADAEHYNAV
CCCCCCCCEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCHHHCCCHHHHHCCCHHHHHHH
RDTLDVWFDSGTTHYAVLRQREELTDPADLYLEGSDQHRGWFQSSLLTSIAINERAPYKG
HHHHHHHCCCCCCHHHHHHHHHHCCCCHHEEEECCCCCCHHHHHHHHHHHHCCCCCCCCC
LLTHGFVVDEKGRKMSKSLGNIITPQDIIKDMGADGLRFWIASSDYRYEMTAGKEIFSRA
HHHCCEEECCCCHHHHHHHCCCCCHHHHHHHCCCCCEEEEEECCCEEEEEHHHHHHHHHH
SDGYRRIRNTLRFLLANLNGFTPSTDALPVDQLIALDQYILQRAAEVQKTVQQAYEDMNF
HHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCE
HIVCSALTNFCINDLGGFYLDIIKDRQYTTKADSAARHSAQTALYHLVQAFVRWMSPILS
EEEHHHHHHHHHHHCCHHEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTAQEAWPLIPEQTEQYVFTTEWYDIPVASTANLISEADWQTLISVKSAVNKQIEAARNA
HHHHHCCCCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
KLVGSNLSAKVEIWAKDELQSVLNQLGDELRFVLITSQVNVYPYAEQGESTEMDGLRVQI
EEECCCCCEEEEEEEHHHHHHHHHHCCCCEEEEEEEECEEEEEECCCCCCCCCCCEEEEE
SAAEGEKCVRCWHVLPDVNTHADHPGLCGRCIINVTGSGEVRKYA
ECCCCHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA