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The map label for this gene is nuoH

Identifier: 49481263

GI number: 49481263

Start: 5032879

End: 5033880

Strand: Reverse

Name: nuoH

Synonym: BT9727_4978

Alternate gene names: 49481263

Gene position: 5033880-5032879 (Counterclockwise)

Preceding gene: 49481375

Following gene: 49481261

Centisome position: 96.11

GC content: 41.62

Gene sequence:

>1002_bases
ATGATTGAAACGCTCTTACAATCACCTTCAAGCTGGACGAATTTCTTCATTTTTTTCGGATTAGCGGTGCTCCTATTATT
TGCAGTCCTTGGCTTCGTTACATATGGAATTTTGGCAGAACGGAAAGTGATGGGTTTTATGCAAGGACGAATTGGGCCAA
ACCAAGTCGGGGGCCGGTTCGGTCTGCTGCAAACGGTAGCTGATGTTTTAAAACTACTACTAAAAGAAGATAGTATTCCG
AAAGCGGCAGATAAACCGTTGTTTATATTAGCGCCTGTTATTGCATTCGCGCCAGCATTTATGGTGCTTGCAGTCATCCC
GTTTACTGATAAATTTCAGTTCGCAGATATTGGCGTAGGCTTACTATATTACATTGCTGTTTCTGGCATTACGACGATTG
GCGTCGTAACGGGAGGATGGGCATCCAATAATAAATATTCCCTTTTAGGAGGGATGCGTGCGGCGGCGCAAATGATTTCT
TATGAAATTCCACTCGTAATGAGTGTAATTGGCATCGTTTTATTAGCTGGTAGCTTAAATTTAAATGAAATTGTAGCGGC
GCAGGAGAATGTTTGGTACATTTTCGTGCAACCAGTCGGTTTCGTCGTATTCTTAATCGCGGCGGTAGCAGAGTTAAATA
GGACGCCGTTTGATTTACCAGAAGCAGAATCGGAACTTGTTTCTGGATATCATACGGAATACTCAGGGTTTCGCTGGGCG
TTTTTCATGCTGTCAGAGTACGTATATTTTTTCGGGATGGCATCGTTAATTACAGTGCTTTTTTTAGGCGGATGGAATCC
AGTTATGTTCCTTGGATTTATCCCAGGTGCCGTATGGTTTGCTTTAAAGTTTAGCAGTGTAGTTTTTCTATTAATTTGGT
TCCGCGTTACGTTTCCGCGTATAAGAGGTGATCAGTTAATGGAGTTTGGCTGGAAAGTATTATTGCCAATTGCACTTGCA
AATATTTTCTTAACGGCATTGATTAAGGAGTTATTCTTCTAA

Upstream 100 bases:

>100_bases
ATTTGCAAATTTTACCGAAGTTATTAAAAGGTGAAAACATCGCCAATTTAATTACGATTTTAGGTGGAGTGGATATTGTA
CTTGGGGAGGTTGATGGCTA

Downstream 100 bases:

>100_bases
TCTATGAGGGGGGTGCCAGTAAGAGATGAAAGGTCTATTTAAAGGGCTAAAATATACACTAAGCAATTTGAGTAAGAAGA
AGGTGACGTATGATTATCCA

Product: NADH dehydrogenase subunit H

Products: NA

Alternate protein names: NADH dehydrogenase I subunit H; NDH-1 subunit H [H]

Number of amino acids: Translated: 333; Mature: 333

Protein sequence:

>333_residues
MIETLLQSPSSWTNFFIFFGLAVLLLFAVLGFVTYGILAERKVMGFMQGRIGPNQVGGRFGLLQTVADVLKLLLKEDSIP
KAADKPLFILAPVIAFAPAFMVLAVIPFTDKFQFADIGVGLLYYIAVSGITTIGVVTGGWASNNKYSLLGGMRAAAQMIS
YEIPLVMSVIGIVLLAGSLNLNEIVAAQENVWYIFVQPVGFVVFLIAAVAELNRTPFDLPEAESELVSGYHTEYSGFRWA
FFMLSEYVYFFGMASLITVLFLGGWNPVMFLGFIPGAVWFALKFSSVVFLLIWFRVTFPRIRGDQLMEFGWKVLLPIALA
NIFLTALIKELFF

Sequences:

>Translated_333_residues
MIETLLQSPSSWTNFFIFFGLAVLLLFAVLGFVTYGILAERKVMGFMQGRIGPNQVGGRFGLLQTVADVLKLLLKEDSIP
KAADKPLFILAPVIAFAPAFMVLAVIPFTDKFQFADIGVGLLYYIAVSGITTIGVVTGGWASNNKYSLLGGMRAAAQMIS
YEIPLVMSVIGIVLLAGSLNLNEIVAAQENVWYIFVQPVGFVVFLIAAVAELNRTPFDLPEAESELVSGYHTEYSGFRWA
FFMLSEYVYFFGMASLITVLFLGGWNPVMFLGFIPGAVWFALKFSSVVFLLIWFRVTFPRIRGDQLMEFGWKVLLPIALA
NIFLTALIKELFF
>Mature_333_residues
MIETLLQSPSSWTNFFIFFGLAVLLLFAVLGFVTYGILAERKVMGFMQGRIGPNQVGGRFGLLQTVADVLKLLLKEDSIP
KAADKPLFILAPVIAFAPAFMVLAVIPFTDKFQFADIGVGLLYYIAVSGITTIGVVTGGWASNNKYSLLGGMRAAAQMIS
YEIPLVMSVIGIVLLAGSLNLNEIVAAQENVWYIFVQPVGFVVFLIAAVAELNRTPFDLPEAESELVSGYHTEYSGFRWA
FFMLSEYVYFFGMASLITVLFLGGWNPVMFLGFIPGAVWFALKFSSVVFLLIWFRVTFPRIRGDQLMEFGWKVLLPIALA
NIFLTALIKELFF

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1005

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 1 (chain H)

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 1 family [H]

Homologues:

Organism=Homo sapiens, GI251831107, Length=288, Percent_Identity=38.1944444444444, Blast_Score=194, Evalue=8e-50,
Organism=Escherichia coli, GI1788618, Length=307, Percent_Identity=43.3224755700326, Blast_Score=265, Evalue=4e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023020
- InterPro:   IPR001694
- InterPro:   IPR018086 [H]

Pfam domain/function: PF00146 NADHdh [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 36881; Mature: 36881

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: PS00668 COMPLEX1_ND1_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIETLLQSPSSWTNFFIFFGLAVLLLFAVLGFVTYGILAERKVMGFMQGRIGPNQVGGRF
CCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHH
GLLQTVADVLKLLLKEDSIPKAADKPLFILAPVIAFAPAFMVLAVIPFTDKFQFADIGVG
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LLYYIAVSGITTIGVVTGGWASNNKYSLLGGMRAAAQMISYEIPLVMSVIGIVLLAGSLN
HHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LNEIVAAQENVWYIFVQPVGFVVFLIAAVAELNRTPFDLPEAESELVSGYHTEYSGFRWA
HHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCHHHH
FFMLSEYVYFFGMASLITVLFLGGWNPVMFLGFIPGAVWFALKFSSVVFLLIWFRVTFPR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IRGDQLMEFGWKVLLPIALANIFLTALIKELFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIETLLQSPSSWTNFFIFFGLAVLLLFAVLGFVTYGILAERKVMGFMQGRIGPNQVGGRF
CCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCHH
GLLQTVADVLKLLLKEDSIPKAADKPLFILAPVIAFAPAFMVLAVIPFTDKFQFADIGVG
HHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LLYYIAVSGITTIGVVTGGWASNNKYSLLGGMRAAAQMISYEIPLVMSVIGIVLLAGSLN
HHHHHHHHHHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
LNEIVAAQENVWYIFVQPVGFVVFLIAAVAELNRTPFDLPEAESELVSGYHTEYSGFRWA
HHHHHHCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCHHHH
FFMLSEYVYFFGMASLITVLFLGGWNPVMFLGFIPGAVWFALKFSSVVFLLIWFRVTFPR
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
IRGDQLMEFGWKVLLPIALANIFLTALIKELFF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA