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The map label for this gene is nuoD

Identifier: 49481375

GI number: 49481375

Start: 5033880

End: 5034980

Strand: Reverse

Name: nuoD

Synonym: BT9727_4979

Alternate gene names: 49481375

Gene position: 5034980-5033880 (Counterclockwise)

Preceding gene: 49480404

Following gene: 49481263

Centisome position: 96.13

GC content: 43.87

Gene sequence:

>1101_bases
ATGATCCGTACGGAAGAAATGCTTTTGAATGTAGGTCCTCAGCATCCGAGTACACACGGTGTGTTCAGGCTTGTTATTAA
GATTGACGGGGAAATTATTAAAGAAGCTACACCGGTTATTGGATATTTGCATCGCGGGACCGAAAAGATTGCAGAGAGCT
TACAGTATACGCAAATCATCCCTTATACAGATCGGATGGATTATTTATCGGCTATGACGAATAATTACGTCATTTGCCAC
GCTGTAGAGACGATGATGGGGCTTGAAATCCCGGAGCGGGCCGAATACTTGCGAGTACTTGCAATGGAGCTTGGAAGGAT
TGCGAGCCACCTCGTTTGGTGGGGGACAAATCTTCTTGATATAGGAGCAGTTAGCCCGTTTTTGTACGCGTTCCGTGAGC
GAGAAATGATTATTAATTTATTAAACGAATTATGCGGTGCACGGCTTACTTTTAACTATATGAGGGTTGGCGGTGTGAAA
TGGGATGCACCGGATGGTTGGATTGAAAAAGTGGAAGAATTTGTTCCATATATGAGAGAACAATTGGCAGGGTATCATGA
TCTTGTTAGCGGCAATGAGATTTTCTTAAATCGTGTAAAAGGCGTTGGTATATATAGCGCGGAGGAAGCGATTTCGTATT
CTTTAAGTGGAGCGAATTTACGATGCACAGGAGTAAACTGGGATCTTCGCAAGGATGAACCATACTCCATTTATGATCGT
TTTGACTTTCATATTCCTGTTGGGAGCGTGGGGGATGCTTGGGATCGCTACGTTTGCCGTATGCAGGAAATTGAGGAGTC
TTTAAAGATTGTTGAGCAAGCAGTCCAGCAGTTTCCAAAAGAAGGAGCTGTGCTGGCGAAAGTGCCGAAAATTATTAAGG
CGCCTAAAGGGGAAGCATTCGTCCGTATAGAGTCGCCGCGCGGAGAGATTGGTTGCTATATTGCTAGTGATGGGAAGAAA
GAGCCGTACCGCTTGAAGTTTCGCAGGCCGTCTTTTTACAATTTGCAAATTTTACCGAAGTTATTAAAAGGTGAAAACAT
CGCCAATTTAATTACGATTTTAGGTGGAGTGGATATTGTACTTGGGGAGGTTGATGGCTAA

Upstream 100 bases:

>100_bases
AAGGGGCATCCGAATTTATCACGTATTTTAATGCCTGATGATTGGGTAGGGCACCCGCTTAGGAAAGATTATGAACCGTA
TGATGTGGAGGTGTAGCTAA

Downstream 100 bases:

>100_bases
TGATTGAAACGCTCTTACAATCACCTTCAAGCTGGACGAATTTCTTCATTTTTTTCGGATTAGCGGTGCTCCTATTATTT
GCAGTCCTTGGCTTCGTTAC

Product: NADH dehydrogenase subunit D

Products: NA

Alternate protein names: NADH dehydrogenase I subunit D; NDH-1 subunit D [H]

Number of amino acids: Translated: 366; Mature: 366

Protein sequence:

>366_residues
MIRTEEMLLNVGPQHPSTHGVFRLVIKIDGEIIKEATPVIGYLHRGTEKIAESLQYTQIIPYTDRMDYLSAMTNNYVICH
AVETMMGLEIPERAEYLRVLAMELGRIASHLVWWGTNLLDIGAVSPFLYAFREREMIINLLNELCGARLTFNYMRVGGVK
WDAPDGWIEKVEEFVPYMREQLAGYHDLVSGNEIFLNRVKGVGIYSAEEAISYSLSGANLRCTGVNWDLRKDEPYSIYDR
FDFHIPVGSVGDAWDRYVCRMQEIEESLKIVEQAVQQFPKEGAVLAKVPKIIKAPKGEAFVRIESPRGEIGCYIASDGKK
EPYRLKFRRPSFYNLQILPKLLKGENIANLITILGGVDIVLGEVDG

Sequences:

>Translated_366_residues
MIRTEEMLLNVGPQHPSTHGVFRLVIKIDGEIIKEATPVIGYLHRGTEKIAESLQYTQIIPYTDRMDYLSAMTNNYVICH
AVETMMGLEIPERAEYLRVLAMELGRIASHLVWWGTNLLDIGAVSPFLYAFREREMIINLLNELCGARLTFNYMRVGGVK
WDAPDGWIEKVEEFVPYMREQLAGYHDLVSGNEIFLNRVKGVGIYSAEEAISYSLSGANLRCTGVNWDLRKDEPYSIYDR
FDFHIPVGSVGDAWDRYVCRMQEIEESLKIVEQAVQQFPKEGAVLAKVPKIIKAPKGEAFVRIESPRGEIGCYIASDGKK
EPYRLKFRRPSFYNLQILPKLLKGENIANLITILGGVDIVLGEVDG
>Mature_366_residues
MIRTEEMLLNVGPQHPSTHGVFRLVIKIDGEIIKEATPVIGYLHRGTEKIAESLQYTQIIPYTDRMDYLSAMTNNYVICH
AVETMMGLEIPERAEYLRVLAMELGRIASHLVWWGTNLLDIGAVSPFLYAFREREMIINLLNELCGARLTFNYMRVGGVK
WDAPDGWIEKVEEFVPYMREQLAGYHDLVSGNEIFLNRVKGVGIYSAEEAISYSLSGANLRCTGVNWDLRKDEPYSIYDR
FDFHIPVGSVGDAWDRYVCRMQEIEESLKIVEQAVQQFPKEGAVLAKVPKIIKAPKGEAFVRIESPRGEIGCYIASDGKK
EPYRLKFRRPSFYNLQILPKLLKGENIANLITILGGVDIVLGEVDG

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translo

COG id: COG0649

COG function: function code C; NADH:ubiquinone oxidoreductase 49 kD subunit 7

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 49 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758786, Length=385, Percent_Identity=39.2207792207792, Blast_Score=306, Evalue=2e-83,
Organism=Homo sapiens, GI260898743, Length=380, Percent_Identity=38.4210526315789, Blast_Score=295, Evalue=6e-80,
Organism=Escherichia coli, GI145693162, Length=385, Percent_Identity=38.7012987012987, Blast_Score=288, Evalue=3e-79,
Organism=Escherichia coli, GI1789076, Length=351, Percent_Identity=27.0655270655271, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI1788832, Length=358, Percent_Identity=25.6983240223464, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17568379, Length=386, Percent_Identity=38.860103626943, Blast_Score=306, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI17555284, Length=386, Percent_Identity=38.0829015544041, Blast_Score=305, Evalue=2e-83,
Organism=Drosophila melanogaster, GI24638644, Length=384, Percent_Identity=39.84375, Blast_Score=323, Evalue=1e-88,
Organism=Drosophila melanogaster, GI221459469, Length=382, Percent_Identity=39.0052356020942, Blast_Score=309, Evalue=2e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010219
- InterPro:   IPR001135
- InterPro:   IPR022885 [H]

Pfam domain/function: PF00346 Complex1_49kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 41529; Mature: 41529

Theoretical pI: Translated: 5.51; Mature: 5.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTEEMLLNVGPQHPSTHGVFRLVIKIDGEIIKEATPVIGYLHRGTEKIAESLQYTQII
CCCCHHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHEEC
PYTDRMDYLSAMTNNYVICHAVETMMGLEIPERAEYLRVLAMELGRIASHLVWWGTNLLD
CCCCHHHHHHHHHCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEH
IGAVSPFLYAFREREMIINLLNELCGARLTFNYMRVGGVKWDAPDGWIEKVEEFVPYMRE
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCEEECCCCHHHHHHHHHHHHHHH
QLAGYHDLVSGNEIFLNRVKGVGIYSAEEAISYSLSGANLRCTGVNWDLRKDEPYSIYDR
HHCCHHHHCCCCCEEEEHHCCCCEEEHHHHHEEEECCCEEEEECCCCCCCCCCCCEEECC
FDFHIPVGSVGDAWDRYVCRMQEIEESLKIVEQAVQQFPKEGAVLAKVPKIIKAPKGEAF
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEE
VRIESPRGEIGCYIASDGKKEPYRLKFRRPSFYNLQILPKLLKGENIANLITILGGVDIV
EEEECCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHCCCEEE
LGEVDG
EEECCC
>Mature Secondary Structure
MIRTEEMLLNVGPQHPSTHGVFRLVIKIDGEIIKEATPVIGYLHRGTEKIAESLQYTQII
CCCCHHHHHCCCCCCCCCCCEEEEEEEECCHHHHHHHHHHHHHHCCHHHHHHHHHHHEEC
PYTDRMDYLSAMTNNYVICHAVETMMGLEIPERAEYLRVLAMELGRIASHLVWWGTNLLD
CCCCHHHHHHHHHCCEEEEEEHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEH
IGAVSPFLYAFREREMIINLLNELCGARLTFNYMRVGGVKWDAPDGWIEKVEEFVPYMRE
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEECCEEECCCCHHHHHHHHHHHHHHH
QLAGYHDLVSGNEIFLNRVKGVGIYSAEEAISYSLSGANLRCTGVNWDLRKDEPYSIYDR
HHCCHHHHCCCCCEEEEHHCCCCEEEHHHHHEEEECCCEEEEECCCCCCCCCCCCEEECC
FDFHIPVGSVGDAWDRYVCRMQEIEESLKIVEQAVQQFPKEGAVLAKVPKIIKAPKGEAF
EEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEE
VRIESPRGEIGCYIASDGKKEPYRLKFRRPSFYNLQILPKLLKGENIANLITILGGVDIV
EEEECCCCCEEEEEECCCCCCCEEEEECCCCCCCHHHHHHHHCCCCHHHHHHHHCCCEEE
LGEVDG
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA