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The map label for this gene is comFA

Identifier: 49481146

GI number: 49481146

Start: 4917817

End: 4919166

Strand: Reverse

Name: comFA

Synonym: BT9727_4872

Alternate gene names: 49481146

Gene position: 4919166-4917817 (Counterclockwise)

Preceding gene: 49481650

Following gene: 49480782

Centisome position: 93.92

GC content: 39.78

Gene sequence:

>1350_bases
ATGGTTGCTGGAAAGCAGTTACTATTAGAAGAACTCTCTTCAGATTTACGGAGAGAATTAAGTGATTTGAAAAAGAAGGG
AGAGGTCATATGTGTACAAGGCGTAATAAAGAAGGTTTCTAAATATATATGTCAGCGCTGCGGGAATATAGAGCAGCGGC
TATTTGCATCATTTTTATGTAAAAGGTGCAGTAAAGTATGTACGTATTGCCGGAAGTGTATAACGATGGGGAGAGTTAGT
GAATGTGCTGTACTTGTTCGCGGGATTCATGAAAGAAAAGGAGAAAGGGAATTACATTCGTTACAGTGGAAAGGGAGTTT
GTCTCTTGGTCAGGAGCTAGCGGCGCAAGGTGTTATAGAAGCTATTAAGCAAAAAGAATCTTTTTTTATTTGGGCTGTGT
GCGGGGCTGGAAAAACAGAAATGTTATTTTACGGTATAGAAGAAGCACTTCAAAAAGGAGAAAGAGTGTGTATCGCAACG
CCAAGGACGGACGTTGTACTGGAATTAGCACCGAGATTACAAGAAGTGTTTCCAAGTATAAATGTAGCTGCTTTATACGG
AGGGAGTGTAGATCGTGAAAAAGATGCAGCGTTAGTCGTTGCAACGACTCACCAACTGTTACGTTACTATAGAGCATTTC
ATGTAATGATTGTAGATGAGATTGATGCCTTCCCGTATCATGCGGATCAAATGTTACAGTATGCAGTGCAGCAAGCGATG
AAAGAGAAAGCAGCGCGTATTTATTTAACTGCAACCCCTGATGAAAAGTGGAAGCGCAATTTCAGAAGGGGGAAACAAAA
AGGTATCATTGTCTCTGGAAGATACCATCGTCATCCGTTACCAGTTCCTCTATTTAGTTGGTGCGGAAATTGGAAGAAAA
GCCTCCATCATAAAAAAATTCCTCGTGTGTTACTACAATGGTTAAAAATGTACGTAAACAAAAAATACCCTATTTTTTTA
TTTGTTCCTCATGTGCGATATATAGAAGAAATGAGCCTGTTATTGAAAGGGTTGGATCATAGAATCGATGGCGTACATGC
AGAAGATCCGATGAGAAAAGAAAAAGTGGCAGCGTTTAGAAAGGGAGACATTCCGTTATTAGTTACAACGACAATTTTAG
AAAGAGGGGTAACTGTGAAGAACTTACAAGTGGCTGTGTTAGGGGCTGAAGAAGAAATATTTTCAGAAAGTGCGCTCGTA
CAAATTGCAGGCCGAGCAGGTCGTAGTTTTGAAGAACCGTATGGTGAGGTTGTTTATTTTCATTACGGTAAGACAGAGTC
GATGGTACGTGCGAAAAGACATATTCAAAGTATGAACAAAAGTGCGAAAGAACAAGGATTAATTGATTAA

Upstream 100 bases:

>100_bases
TAAAGTCGATAGCTTACTATTTTATAAGTAGGTTATCGGCTTTTTTGAGTTTTTACGAGATTATAAGAAAGGTTTATAGT
AATGCTGGGGGTGGTTACGG

Downstream 100 bases:

>100_bases
TGCATTGTTTACTTTGTGATGAATATATGTTGGAAACAGTTAGTTGGTACACTTTCTTTGTAAAGTCTCATAAAAAATAT
GTATGTGATAGATGTGAGCG

Product: comF operon protein 1

Products: NA

Alternate protein names: ATP-dependent helicase ComFA [H]

Number of amino acids: Translated: 449; Mature: 449

Protein sequence:

>449_residues
MVAGKQLLLEELSSDLRRELSDLKKKGEVICVQGVIKKVSKYICQRCGNIEQRLFASFLCKRCSKVCTYCRKCITMGRVS
ECAVLVRGIHERKGERELHSLQWKGSLSLGQELAAQGVIEAIKQKESFFIWAVCGAGKTEMLFYGIEEALQKGERVCIAT
PRTDVVLELAPRLQEVFPSINVAALYGGSVDREKDAALVVATTHQLLRYYRAFHVMIVDEIDAFPYHADQMLQYAVQQAM
KEKAARIYLTATPDEKWKRNFRRGKQKGIIVSGRYHRHPLPVPLFSWCGNWKKSLHHKKIPRVLLQWLKMYVNKKYPIFL
FVPHVRYIEEMSLLLKGLDHRIDGVHAEDPMRKEKVAAFRKGDIPLLVTTTILERGVTVKNLQVAVLGAEEEIFSESALV
QIAGRAGRSFEEPYGEVVYFHYGKTESMVRAKRHIQSMNKSAKEQGLID

Sequences:

>Translated_449_residues
MVAGKQLLLEELSSDLRRELSDLKKKGEVICVQGVIKKVSKYICQRCGNIEQRLFASFLCKRCSKVCTYCRKCITMGRVS
ECAVLVRGIHERKGERELHSLQWKGSLSLGQELAAQGVIEAIKQKESFFIWAVCGAGKTEMLFYGIEEALQKGERVCIAT
PRTDVVLELAPRLQEVFPSINVAALYGGSVDREKDAALVVATTHQLLRYYRAFHVMIVDEIDAFPYHADQMLQYAVQQAM
KEKAARIYLTATPDEKWKRNFRRGKQKGIIVSGRYHRHPLPVPLFSWCGNWKKSLHHKKIPRVLLQWLKMYVNKKYPIFL
FVPHVRYIEEMSLLLKGLDHRIDGVHAEDPMRKEKVAAFRKGDIPLLVTTTILERGVTVKNLQVAVLGAEEEIFSESALV
QIAGRAGRSFEEPYGEVVYFHYGKTESMVRAKRHIQSMNKSAKEQGLID
>Mature_449_residues
MVAGKQLLLEELSSDLRRELSDLKKKGEVICVQGVIKKVSKYICQRCGNIEQRLFASFLCKRCSKVCTYCRKCITMGRVS
ECAVLVRGIHERKGERELHSLQWKGSLSLGQELAAQGVIEAIKQKESFFIWAVCGAGKTEMLFYGIEEALQKGERVCIAT
PRTDVVLELAPRLQEVFPSINVAALYGGSVDREKDAALVVATTHQLLRYYRAFHVMIVDEIDAFPYHADQMLQYAVQQAM
KEKAARIYLTATPDEKWKRNFRRGKQKGIIVSGRYHRHPLPVPLFSWCGNWKKSLHHKKIPRVLLQWLKMYVNKKYPIFL
FVPHVRYIEEMSLLLKGLDHRIDGVHAEDPMRKEKVAAFRKGDIPLLVTTTILERGVTVKNLQVAVLGAEEEIFSESALV
QIAGRAGRSFEEPYGEVVYFHYGKTESMVRAKRHIQSMNKSAKEQGLID

Specific function: Involved in transformation (competence for DNA uptake). Required for DNA uptake but not for binding. May provide the driving force for transport of DNA through an aqueous channel [H]

COG id: COG4098

COG function: function code L; Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 helicase C-terminal domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR006935 [H]

Pfam domain/function: PF00271 Helicase_C; PF04851 ResIII [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 51255; Mature: 51255

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAGKQLLLEELSSDLRRELSDLKKKGEVICVQGVIKKVSKYICQRCGNIEQRLFASFLC
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KRCSKVCTYCRKCITMGRVSECAVLVRGIHERKGERELHSLQWKGSLSLGQELAAQGVIE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
AIKQKESFFIWAVCGAGKTEMLFYGIEEALQKGERVCIATPRTDVVLELAPRLQEVFPSI
HHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCC
NVAALYGGSVDREKDAALVVATTHQLLRYYRAFHVMIVDEIDAFPYHADQMLQYAVQQAM
CEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHH
KEKAARIYLTATPDEKWKRNFRRGKQKGIIVSGRYHRHPLPVPLFSWCGNWKKSLHHKKI
HHHHCEEEEEECCCHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHCCCHHHHHHHHHH
PRVLLQWLKMYVNKKYPIFLFVPHVRYIEEMSLLLKGLDHRIDGVHAEDPMRKEKVAAFR
HHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
KGDIPLLVTTTILERGVTVKNLQVAVLGAEEEIFSESALVQIAGRAGRSFEEPYGEVVYF
CCCCCEEEHHHHHHCCCEEECEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
HYGKTESMVRAKRHIQSMNKSAKEQGLID
EECCHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MVAGKQLLLEELSSDLRRELSDLKKKGEVICVQGVIKKVSKYICQRCGNIEQRLFASFLC
CCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
KRCSKVCTYCRKCITMGRVSECAVLVRGIHERKGERELHSLQWKGSLSLGQELAAQGVIE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHH
AIKQKESFFIWAVCGAGKTEMLFYGIEEALQKGERVCIATPRTDVVLELAPRLQEVFPSI
HHHCCCCEEEEEEECCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCC
NVAALYGGSVDREKDAALVVATTHQLLRYYRAFHVMIVDEIDAFPYHADQMLQYAVQQAM
CEEEEECCCCCCCCCCEEEEHHHHHHHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHH
KEKAARIYLTATPDEKWKRNFRRGKQKGIIVSGRYHRHPLPVPLFSWCGNWKKSLHHKKI
HHHHCEEEEEECCCHHHHHHHHCCCCCCEEEECCCCCCCCCCHHHHHCCCHHHHHHHHHH
PRVLLQWLKMYVNKKYPIFLFVPHVRYIEEMSLLLKGLDHRIDGVHAEDPMRKEKVAAFR
HHHHHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
KGDIPLLVTTTILERGVTVKNLQVAVLGAEEEIFSESALVQIAGRAGRSFEEPYGEVVYF
CCCCCEEEHHHHHHCCCEEECEEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEE
HYGKTESMVRAKRHIQSMNKSAKEQGLID
EECCHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8412657; 9384377 [H]