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The map label for this gene is argD

Identifier: 49480909

GI number: 49480909

Start: 3959193

End: 3960353

Strand: Reverse

Name: argD

Synonym: BT9727_3876

Alternate gene names: 49480909

Gene position: 3960353-3959193 (Counterclockwise)

Preceding gene: 49478551

Following gene: 49478550

Centisome position: 75.61

GC content: 38.42

Gene sequence:

>1161_bases
ATGACAAGTCATCTTTTTCAAACGTATGGGAGAAGAAATGTTGAGTTTGTAAAGGGGAATGGAACGAAAGTCATTGATAA
CAACGGTAAACAATATTTAGATTTCACATCAGGGATTGGTGTATGTAATTTAGGGCATTGCCATCCTACTGTTATGAAAG
CGGTACAAGAGCAACTTAATGATATATGGCATATATCTAATCTGTTTACAAACAGCTTACAAGAAGAAGTCGCGTCATTA
TTAACAGAAAATATAGCATTAGATTATGTGTTTTTCTGTAATAGCGGGGCAGAGGCGAATGAAGCAGCTTTGAAGCTAGC
TCGTAAGCATACTGGAAAATCTCTCGTCGTAACGTGTGAACAGTCTTTTCACGGTAGAACATTCGGAACGATGAGTGCGA
CGGGGCAAAATAAAGTGAAAGAAGGATTTGGTCCGCTCCTTCCGTCTTTTTTACATACTCCATTTAACGATATAAAGGCG
CTCAAGGAAGTAATGAATGAAGAAGTTGCGGCAGTAATGGTAGAAGTTGTTCAAGGAGAGGGAGGAGTTATACCTGCTGA
TCTATCCTTTTTGAAAGAGATTGAAACATTATGTAAGAAGTTTGGTTCCTTATTTATTATAGACGAAGTACAAACAGGGA
TCGGAAGAACAGGTACATTATTTGCTTACGAACAAATGGGAATAGATCCTCATATCGTTACTACCGCTAAGGCGCTTGGA
AATGGGATTCCTGTTGGAGCAATGATTGGTCGGAAAGAACTCGGAACGTCGTTCACTGCAGGATCGCACGGTTCAACGTT
TGGCGGAAATTATGTTGCAATGGCTGCAGCGGAAGCAGTATTGCAAGTAAGTAAAAGACCATCGTTTTTAAAAGAAGTAC
AAGAAAAGGGCGAGTATGTATTACAGAAGTTGCAAGAGGAATTACAACATGTCGAATGTATTCAAAATATACGTGGTAAG
GGGCTTATGGTTGGAATTGAATGTACGCATGAAGTTACAAGTTTTATAGAACAACTAGAAAAAGAGGGACTGCTCGTATT
ACAAGCAGGGCCTACTGTTATAAGACTATTACCACCACTTATTGTGACGAATGAAGAGTTAGAACAGGCAGTATATATAA
TAAAAAAAGTAGTTTGTACAAAAAACGTATCAATCATATAA

Upstream 100 bases:

>100_bases
TGGGAGTGCAAAAGATAAGTATCGTAAATGGTACAAAAGATTTTACTGAAGATACAGGAGAATGTATTGGAACGACGGTA
ACGAGGGGAGTGAGTATTGT

Downstream 100 bases:

>100_bases
GGGGGAAGTTTCATGTCAACTGTACAAGTACCGAAATTAAATACGAAAGATCTTTTAACACTAGAAGAATTAACGAAAGA
AGAAATTATTTCTTTAATTG

Product: acetylornithine aminotransferase

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 386; Mature: 385

Protein sequence:

>386_residues
MTSHLFQTYGRRNVEFVKGNGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLNDIWHISNLFTNSLQEEVASL
LTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCEQSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKA
LKEVMNEEVAAVMVEVVQGEGGVIPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIDPHIVTTAKALG
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAEAVLQVSKRPSFLKEVQEKGEYVLQKLQEELQHVECIQNIRGK
GLMVGIECTHEVTSFIEQLEKEGLLVLQAGPTVIRLLPPLIVTNEELEQAVYIIKKVVCTKNVSII

Sequences:

>Translated_386_residues
MTSHLFQTYGRRNVEFVKGNGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLNDIWHISNLFTNSLQEEVASL
LTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCEQSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKA
LKEVMNEEVAAVMVEVVQGEGGVIPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIDPHIVTTAKALG
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAEAVLQVSKRPSFLKEVQEKGEYVLQKLQEELQHVECIQNIRGK
GLMVGIECTHEVTSFIEQLEKEGLLVLQAGPTVIRLLPPLIVTNEELEQAVYIIKKVVCTKNVSII
>Mature_385_residues
TSHLFQTYGRRNVEFVKGNGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLNDIWHISNLFTNSLQEEVASLL
TENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCEQSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKAL
KEVMNEEVAAVMVEVVQGEGGVIPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIDPHIVTTAKALGN
GIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAEAVLQVSKRPSFLKEVQEKGEYVLQKLQEELQHVECIQNIRGKG
LMVGIECTHEVTSFIEQLEKEGLLVLQAGPTVIRLLPPLIVTNEELEQAVYIIKKVVCTKNVSII

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=391, Percent_Identity=32.7365728900256, Blast_Score=209, Evalue=5e-54,
Organism=Homo sapiens, GI13994255, Length=433, Percent_Identity=30.715935334873, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI284507298, Length=301, Percent_Identity=33.8870431893688, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI37574042, Length=422, Percent_Identity=27.7251184834123, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI24119277, Length=401, Percent_Identity=27.930174563591, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI226442709, Length=392, Percent_Identity=27.5510204081633, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI226442705, Length=422, Percent_Identity=26.7772511848341, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI188536080, Length=429, Percent_Identity=22.3776223776224, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI38679950, Length=429, Percent_Identity=22.3776223776224, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI38679946, Length=429, Percent_Identity=22.3776223776224, Blast_Score=86, Evalue=4e-17,
Organism=Escherichia coli, GI1789759, Length=376, Percent_Identity=41.2234042553192, Blast_Score=304, Evalue=5e-84,
Organism=Escherichia coli, GI1788044, Length=361, Percent_Identity=41.5512465373961, Blast_Score=293, Evalue=1e-80,
Organism=Escherichia coli, GI145693181, Length=395, Percent_Identity=35.9493670886076, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1789016, Length=396, Percent_Identity=32.5757575757576, Blast_Score=204, Evalue=1e-53,
Organism=Escherichia coli, GI1787560, Length=386, Percent_Identity=33.160621761658, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1786349, Length=327, Percent_Identity=30.2752293577982, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1786991, Length=403, Percent_Identity=28.287841191067, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=384, Percent_Identity=35.4166666666667, Blast_Score=234, Evalue=8e-62,
Organism=Caenorhabditis elegans, GI32564660, Length=434, Percent_Identity=31.7972350230415, Blast_Score=199, Evalue=2e-51,
Organism=Caenorhabditis elegans, GI25144274, Length=376, Percent_Identity=31.1170212765957, Blast_Score=182, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI71992977, Length=410, Percent_Identity=30, Blast_Score=167, Evalue=1e-41,
Organism=Caenorhabditis elegans, GI71981843, Length=186, Percent_Identity=31.7204301075269, Blast_Score=102, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI17541228, Length=439, Percent_Identity=23.6902050113895, Blast_Score=86, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6324432, Length=392, Percent_Identity=35.969387755102, Blast_Score=251, Evalue=2e-67,
Organism=Saccharomyces cerevisiae, GI6323470, Length=402, Percent_Identity=33.3333333333333, Blast_Score=211, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6324386, Length=358, Percent_Identity=26.2569832402235, Blast_Score=100, Evalue=3e-22,
Organism=Saccharomyces cerevisiae, GI6321456, Length=366, Percent_Identity=25.4098360655738, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21357415, Length=389, Percent_Identity=31.8766066838046, Blast_Score=208, Evalue=6e-54,
Organism=Drosophila melanogaster, GI28574759, Length=411, Percent_Identity=31.1435523114355, Blast_Score=190, Evalue=2e-48,
Organism=Drosophila melanogaster, GI161085790, Length=408, Percent_Identity=31.3725490196078, Blast_Score=189, Evalue=2e-48,
Organism=Drosophila melanogaster, GI21356575, Length=408, Percent_Identity=31.1274509803922, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI281366494, Length=418, Percent_Identity=25.1196172248804, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24667139, Length=418, Percent_Identity=25.1196172248804, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI24667143, Length=418, Percent_Identity=25.1196172248804, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 42106; Mature: 41975

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSHLFQTYGRRNVEFVKGNGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLN
CCCHHHHHHCCCCEEEEECCCCEEEECCCCEEEECCCCCCEECCCCCCHHHHHHHHHHHH
DIWHISNLFTNSLQEEVASLLTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEC
QSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKALKEVMNEEVAAVMVEVVQGE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
GGVIPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIDPHIVTTAKALG
CCCCCHHHHHHHHHHHHHHHHCCEEEEECHHHCCCCCCEEEEHHHCCCCCHHHHHHHHHC
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAEAVLQVSKRPSFLKEVQEKGEYV
CCCCCHHHHCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQKLQEELQHVECIQNIRGKGLMVGIECTHEVTSFIEQLEKEGLLVLQAGPTVIRLLPPL
HHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCH
IVTNEELEQAVYIIKKVVCTKNVSII
HCCCHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TSHLFQTYGRRNVEFVKGNGTKVIDNNGKQYLDFTSGIGVCNLGHCHPTVMKAVQEQLN
CCHHHHHHCCCCEEEEECCCCEEEECCCCEEEECCCCCCEECCCCCCHHHHHHHHHHHH
DIWHISNLFTNSLQEEVASLLTENIALDYVFFCNSGAEANEAALKLARKHTGKSLVVTCE
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHCCCCEEEEEEC
QSFHGRTFGTMSATGQNKVKEGFGPLLPSFLHTPFNDIKALKEVMNEEVAAVMVEVVQGE
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
GGVIPADLSFLKEIETLCKKFGSLFIIDEVQTGIGRTGTLFAYEQMGIDPHIVTTAKALG
CCCCCHHHHHHHHHHHHHHHHCCEEEEECHHHCCCCCCEEEEHHHCCCCCHHHHHHHHHC
NGIPVGAMIGRKELGTSFTAGSHGSTFGGNYVAMAAAEAVLQVSKRPSFLKEVQEKGEYV
CCCCCHHHHCHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LQKLQEELQHVECIQNIRGKGLMVGIECTHEVTSFIEQLEKEGLLVLQAGPTVIRLLPPL
HHHHHHHHHHHHHHHHCCCCEEEEEEECHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCH
IVTNEELEQAVYIIKKVVCTKNVSII
HCCCHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]