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The map label for this gene is nuoC

Identifier: 49480404

GI number: 49480404

Start: 5034985

End: 5036334

Strand: Reverse

Name: nuoC

Synonym: BT9727_4980

Alternate gene names: 49480404

Gene position: 5036334-5034985 (Counterclockwise)

Preceding gene: 49481270

Following gene: 49481375

Centisome position: 96.16

GC content: 46.22

Gene sequence:

>1350_bases
ATGAGTGATCCTAACAAAGACTTAGAGGATTTAAAAAGAGAAGCGGCTAGGCGTGCGAAAGAAGAGGCGAGAAAGCGTCT
CGTTGCGAAACATGGTGTGGAAATAAGTAAACTTGAGGAAGAAAATCGCGAAAAAGAGAAAGCGCTACCAAAAAATGACG
ATATGACTATAGAAGAAGCAAAACGACGTGCAGCCGCGGCCGCAAAAGCAAAAGCGGCGTCGTTAGCGAAGCAGAAAAGA
GAAGGAATAGAAGAAGTAACGGAAGAAGAAAAGGCCAAAGCGAAGGCGAAGGCAGCTGCGGCCGCAAAAGCAAAAGCAGC
GTCGTTAGCGAAGCAGAAAAGAGAAGGAATAGAAGAAGTAACGGAAGAGGAAAAGGTCAAAGCGAAGGCAGCGGCAAAAG
CAAAAGCGGCGTCGTTAGCGAAGCAGAAAAGAGAAGGAACAGAAGAAGTAACGGAAGAAGAAAAGGCGAAAGCGAAGGCA
GCGGCAGCTGCAAAAGCAAAAGCAAAAGCGGCGGCGTTAGCGAAACAGAAAAGAGAAGGAACAGAAGAAGTAACGGAAGA
AGAAAAGGCCAAAGCGAAGGTGAAGGCAGCTGCAAAAGCAAAAGCGGCGGCGTTAGCGAAGCAGAAAAGAGAAGGAACAG
AAGAAGTAACGGAAGAAGAAAAGGCGAAAGCGAAAGCGAAGGCAGTCGCAGCCGCGAAAGCAAAAGCAGCAGCGTTAGCG
AAGCAGAAAGCATCGCAAGGTAATGGAGATTCGGGAGATGAAAAGGCGAAGGCAATTGCAGCAGCAAAGGCAAAAGCGGC
AGCGGCTGCAAGGGCGAAGACAAAGGGTGCTGAAGGTAAGAAGGAAGAGGAGCCGAAGCAGGAAGAGCCATCCGTGAATG
AACCGTATTTAAATCAGTATGTTGAAGTTATTAAGGGAAAGATAGGAGAGGATATATTAGTAGATTTCTACATTAATAAA
CTGTCAAAAGATGTACCAACTCTTGTGGTGGAACCTGCAAAATATTATGAAGTAATGGAGTTACTGCGATTCCATGAGGG
ACTTGCATTTGATTATATGTCAGAGCTACATGCGACGGATTTTGTGACACATATGGAAGTGTATGTTCATTTATTTTCAT
ATGGAAAGAAACAGTCAGTAGCGGTGAAGGTGAAGCTGGATAGGGAAGCGCCGCAAGTGGAATCGGTGACAGCGCTTTGG
AAAGGAGCGGACTGGCCAGAGCGGGAAGCGTATGATTTGCTTGGTATTGTATTTAAGGGGCATCCGAATTTATCACGTAT
TTTAATGCCTGATGATTGGGTAGGGCACCCGCTTAGGAAAGATTATGAACCGTATGATGTGGAGGTGTAG

Upstream 100 bases:

>100_bases
CTGGTTGCCCACCAAATCCTGCAGCTTTAATTTATGGAATTAATAAATTAAAAGAAAAAATTCGTTACGAAGCAAAGACT
GGAAAGCAGGTGACGAATAA

Downstream 100 bases:

>100_bases
CTAAATGATCCGTACGGAAGAAATGCTTTTGAATGTAGGTCCTCAGCATCCGAGTACACACGGTGTGTTCAGGCTTGTTA
TTAAGATTGACGGGGAAATT

Product: NADH dehydrogenase subunit C

Products: NA

Alternate protein names: NADH dehydrogenase I subunit C; NDH-1 subunit C [H]

Number of amino acids: Translated: 449; Mature: 448

Protein sequence:

>449_residues
MSDPNKDLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEAKRRAAAAAKAKAASLAKQKR
EGIEEVTEEEKAKAKAKAAAAAKAKAASLAKQKREGIEEVTEEEKVKAKAAAKAKAASLAKQKREGTEEVTEEEKAKAKA
AAAAKAKAKAAALAKQKREGTEEVTEEEKAKAKVKAAAKAKAAALAKQKREGTEEVTEEEKAKAKAKAVAAAKAKAAALA
KQKASQGNGDSGDEKAKAIAAAKAKAAAAARAKTKGAEGKKEEEPKQEEPSVNEPYLNQYVEVIKGKIGEDILVDFYINK
LSKDVPTLVVEPAKYYEVMELLRFHEGLAFDYMSELHATDFVTHMEVYVHLFSYGKKQSVAVKVKLDREAPQVESVTALW
KGADWPEREAYDLLGIVFKGHPNLSRILMPDDWVGHPLRKDYEPYDVEV

Sequences:

>Translated_449_residues
MSDPNKDLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEAKRRAAAAAKAKAASLAKQKR
EGIEEVTEEEKAKAKAKAAAAAKAKAASLAKQKREGIEEVTEEEKVKAKAAAKAKAASLAKQKREGTEEVTEEEKAKAKA
AAAAKAKAKAAALAKQKREGTEEVTEEEKAKAKVKAAAKAKAAALAKQKREGTEEVTEEEKAKAKAKAVAAAKAKAAALA
KQKASQGNGDSGDEKAKAIAAAKAKAAAAARAKTKGAEGKKEEEPKQEEPSVNEPYLNQYVEVIKGKIGEDILVDFYINK
LSKDVPTLVVEPAKYYEVMELLRFHEGLAFDYMSELHATDFVTHMEVYVHLFSYGKKQSVAVKVKLDREAPQVESVTALW
KGADWPEREAYDLLGIVFKGHPNLSRILMPDDWVGHPLRKDYEPYDVEV
>Mature_448_residues
SDPNKDLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEAKRRAAAAAKAKAASLAKQKRE
GIEEVTEEEKAKAKAKAAAAAKAKAASLAKQKREGIEEVTEEEKVKAKAAAKAKAASLAKQKREGTEEVTEEEKAKAKAA
AAAKAKAKAAALAKQKREGTEEVTEEEKAKAKVKAAAKAKAAALAKQKREGTEEVTEEEKAKAKAKAVAAAKAKAAALAK
QKASQGNGDSGDEKAKAIAAAKAKAAAAARAKTKGAEGKKEEEPKQEEPSVNEPYLNQYVEVIKGKIGEDILVDFYINKL
SKDVPTLVVEPAKYYEVMELLRFHEGLAFDYMSELHATDFVTHMEVYVHLFSYGKKQSVAVKVKLDREAPQVESVTALWK
GADWPEREAYDLLGIVFKGHPNLSRILMPDDWVGHPLRKDYEPYDVEV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG0852

COG function: function code C; NADH:ubiquinone oxidoreductase 27 kD subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I 30 kDa subunit family [H]

Homologues:

Organism=Homo sapiens, GI4758788, Length=118, Percent_Identity=33.8983050847458, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI145693162, Length=100, Percent_Identity=44, Blast_Score=92, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71990788, Length=118, Percent_Identity=36.4406779661017, Blast_Score=82, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI32563621, Length=118, Percent_Identity=36.4406779661017, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010218
- InterPro:   IPR001268
- ProDom:   PD001581 [H]

Pfam domain/function: PF00329 Complex1_30kDa [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 49092; Mature: 48961

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDPNKDLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEA
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHH
KRRAAAAAKAKAASLAKQKREGIEEVTEEEKAKAKAKAAAAAKAKAASLAKQKREGIEEV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TEEEKVKAKAAAKAKAASLAKQKREGTEEVTEEEKAKAKAAAAAKAKAKAAALAKQKREG
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TEEVTEEEKAKAKVKAAAKAKAAALAKQKREGTEEVTEEEKAKAKAKAVAAAKAKAAALA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KQKASQGNGDSGDEKAKAIAAAKAKAAAAARAKTKGAEGKKEEEPKQEEPSVNEPYLNQY
HHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHH
VEVIKGKIGEDILVDFYINKLSKDVPTLVVEPAKYYEVMELLRFHEGLAFDYMSELHATD
HHHHHHHCCCHHHHHHHHHHHCCCCCCEEECHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
FVTHMEVYVHLFSYGKKQSVAVKVKLDREAPQVESVTALWKGADWPEREAYDLLGIVFKG
HHHHHHHHHHHHHCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
HPNLSRILMPDDWVGHPLRKDYEPYDVEV
CCCCCEEECCCCCCCCCHHCCCCCCCCCC
>Mature Secondary Structure 
SDPNKDLEDLKREAARRAKEEARKRLVAKHGVEISKLEEENREKEKALPKNDDMTIEEA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCHHHH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CCCCCEEECCCCCCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA