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The map label for this gene is serC

Identifier: 49480113

GI number: 49480113

Start: 3106138

End: 3107220

Strand: Reverse

Name: serC

Synonym: BT9727_3023

Alternate gene names: 49480113

Gene position: 3107220-3106138 (Counterclockwise)

Preceding gene: 49478103

Following gene: 49480110

Centisome position: 59.32

GC content: 36.01

Gene sequence:

>1083_bases
ATGGAGAGAGTGTATAATTTTTCAGCTGGACCATCAATACTCCCTTTGCCAGTTTTAGAAAAAGTGCAAAAGGAGCTTGT
AAATTATAACGGGACAGGCATGTCTATTATGGAAATGAGTCACCGATCTTCTTATTTTCAAAGTATTATAGATGAAGCGG
GTAGCTTACTTCGTGAATTAATGAACATTCCTGATGAGTATGAAGTATTGTTTTTACAAGGTGGTGCTTCATTACAATTC
TCTATGATACCGTTAAATTTAATGAATACGTATAAAAAAGCAGGGTACGTATTGACTGGTTCATGGTCTAAAAAGGCACT
GCAAGAAGCTGAAAAAGTTGGAGAAGTACAAGTGATTGCTTCTTCTGAAAATGAGAAGTTTACTACAATTCCTAAACTGG
ATGGTTTATTAGGCAATGAAAAACTAGATTATGTACATATAACAACGAATAATACAATAGAGGGTACGAAATATGTGGAC
ATTCCACATGTAGATAAAGTACCACTCGTTGCGGATATGTCCTCAAATATTTTATCAGAACGATATGATGTTTCAAAGTT
TGGTCTTATATATGCGGGAGCGCAAAAGAACCTAGGGCCAGCGGGCTTAACGATTGCAATTATAAAAAGAGATTTAATTG
GAGGAGCAGATCGTTATTGTCCTACAATGTTAAACTATGAAACTTACAGTAAAAATAACTCCTTATATAATACACCGCCA
TCCTTTAGTATTTACGTAACAAAAATTGTATTAGAGTGGCTGAAAGAGCAAGGCGGAGTATCTGCGATTGAAGAACAAAA
TAAAATGAAATCTTCACTTCTTTACAATTTCTTAGATGAATCAAAATTGTTTACTTCACCAGTTGATCCTACGTATCGTT
CACTTATGAACATTCCGTTTACAACGCCGTCAGAAGAGCTGAACAATGAGTTTTTACAAAAAGCGAAAGAACGCGGCCTT
GTTACGCTAAAAGGACATCGATCAGTAGGTGGTATGCGCGCTAGTATTTACAATGCGATGCCAGCACACGGCGTACAGCA
ATTAGTAAATTATATGAAGGAATTTGAGCTTGAGAATAGATAG

Upstream 100 bases:

>100_bases
CCGTAATAATAGAAAACAAATTGACCGTGTCTTGTATTGTAGGGTATAATTCAGAAAGTTTAAAAAATAAAAGATGAGAA
ATAGGGAGGTTATTAGGGTG

Downstream 100 bases:

>100_bases
GGAGATGGGGATATGTTTCGTGTTCAAACGTTAAATCAAATTGCAGAAAAAGGTTTGCAAGTGCTTGGCGGAGAGCGCTA
TGAAGTAGGGGAGAGAATGG

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLRELMNIPDEYEVLFLQGGASLQF
SMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSENEKFTTIPKLDGLLGNEKLDYVHITTNNTIEGTKYVD
IPHVDKVPLVADMSSNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSKNNSLYNTPP
SFSIYVTKIVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLFTSPVDPTYRSLMNIPFTTPSEELNNEFLQKAKERGL
VTLKGHRSVGGMRASIYNAMPAHGVQQLVNYMKEFELENR

Sequences:

>Translated_360_residues
MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLRELMNIPDEYEVLFLQGGASLQF
SMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSENEKFTTIPKLDGLLGNEKLDYVHITTNNTIEGTKYVD
IPHVDKVPLVADMSSNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSKNNSLYNTPP
SFSIYVTKIVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLFTSPVDPTYRSLMNIPFTTPSEELNNEFLQKAKERGL
VTLKGHRSVGGMRASIYNAMPAHGVQQLVNYMKEFELENR
>Mature_360_residues
MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLRELMNIPDEYEVLFLQGGASLQF
SMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIASSENEKFTTIPKLDGLLGNEKLDYVHITTNNTIEGTKYVD
IPHVDKVPLVADMSSNILSERYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSKNNSLYNTPP
SFSIYVTKIVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLFTSPVDPTYRSLMNIPFTTPSEELNNEFLQKAKERGL
VTLKGHRSVGGMRASIYNAMPAHGVQQLVNYMKEFELENR

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=361, Percent_Identity=47.6454293628809, Blast_Score=340, Evalue=1e-93,
Organism=Homo sapiens, GI10863955, Length=356, Percent_Identity=42.6966292134831, Blast_Score=288, Evalue=7e-78,
Organism=Escherichia coli, GI1787136, Length=366, Percent_Identity=42.6229508196721, Blast_Score=314, Evalue=6e-87,
Organism=Caenorhabditis elegans, GI17506897, Length=360, Percent_Identity=44.7222222222222, Blast_Score=323, Evalue=7e-89,
Organism=Saccharomyces cerevisiae, GI6324758, Length=389, Percent_Identity=40.3598971722365, Blast_Score=286, Evalue=4e-78,
Organism=Drosophila melanogaster, GI21356589, Length=363, Percent_Identity=48.2093663911846, Blast_Score=340, Evalue=1e-93,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40367; Mature: 40367

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS00595 AA_TRANSFER_CLASS_5

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLREL
CCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MNIPDEYEVLFLQGGASLQFSMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIA
HCCCCCEEEEEEECCCCEEEEEECHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCEEEEE
SSENEKFTTIPKLDGLLGNEKLDYVHITTNNTIEGTKYVDIPHVDKVPLVADMSSNILSE
CCCCCCEEECCCHHCCCCCCCEEEEEEEECCEECCCEEECCCCCCCCCCHHHHHHHHHHH
RYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSKNNSLYNTPP
HCCHHHCCEEEECCCCCCCCCCEEEEEEHHHHCCCCCHHCCHHCCCEEECCCCCCCCCCC
SFSIYVTKIVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLFTSPVDPTYRSLMNIPF
CCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCC
TTPSEELNNEFLQKAKERGLVTLKGHRSVGGMRASIYNAMPAHGVQQLVNYMKEFELENR
CCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MERVYNFSAGPSILPLPVLEKVQKELVNYNGTGMSIMEMSHRSSYFQSIIDEAGSLLREL
CCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
MNIPDEYEVLFLQGGASLQFSMIPLNLMNTYKKAGYVLTGSWSKKALQEAEKVGEVQVIA
HCCCCCEEEEEEECCCCEEEEEECHHHHHHHHHCCEEEECCCHHHHHHHHHHCCCEEEEE
SSENEKFTTIPKLDGLLGNEKLDYVHITTNNTIEGTKYVDIPHVDKVPLVADMSSNILSE
CCCCCCEEECCCHHCCCCCCCEEEEEEEECCEECCCEEECCCCCCCCCCHHHHHHHHHHH
RYDVSKFGLIYAGAQKNLGPAGLTIAIIKRDLIGGADRYCPTMLNYETYSKNNSLYNTPP
HCCHHHCCEEEECCCCCCCCCCEEEEEEHHHHCCCCCHHCCHHCCCEEECCCCCCCCCCC
SFSIYVTKIVLEWLKEQGGVSAIEEQNKMKSSLLYNFLDESKLFTSPVDPTYRSLMNIPF
CCEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCC
TTPSEELNNEFLQKAKERGLVTLKGHRSVGGMRASIYNAMPAHGVQQLVNYMKEFELENR
CCCHHHHHHHHHHHHHHCCEEEEECCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA