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The map label for this gene is hutG

Identifier: 49478308

GI number: 49478308

Start: 3481867

End: 3482838

Strand: Reverse

Name: hutG

Synonym: BT9727_3402

Alternate gene names: 49478308

Gene position: 3482838-3481867 (Counterclockwise)

Preceding gene: 49478309

Following gene: 49479453

Centisome position: 66.5

GC content: 39.3

Gene sequence:

>972_bases
GTGGAGCACGGCCACTATTTAAAGAAAAATGCCAAGTTTATCGATCGTGAAGTGACAAAATGGAGTGAAATGATTAAAGA
TTGGGAGGAAGGCGTGGAAATATTCGGTGCGGCCTTAATTGGAGCACCCCTTTCTAAACCGTCTATTAGTCATTCAGGAG
CAAGTTTTGCTCCAAAAACAATTCGTGCGATGTTAGATGCATATAGCACGTATGCAATTACAGAAGAACATGATATGAAA
GAAAGTGTCTTATATGATTGCGGCGATATTACGATGCATGTGACGAATATAAAAGAAAGTCATAACCGAATTGCGAAAAC
AGTTGGTCATGTAACGAAAGTAAATCCGAACATGATACCAATCGTTCTTGGTGGGGATCACTCGATTAGTTTTCCGAGTA
TAACAGGATTTGCAAATAGTAAAGGGAAGGTCGGTATTATTCAATTTGATGCCCATCATGATTTGCGCAATTTAGAAGAT
GGTGGTCCGTCAAATGGTACACCGTTCCGTAGTTTACTAGAAAATGATGTGATTACAGGAAAACAACTCGTTCAAATCGG
AATTCGTAATTTTTCAAATGCACGAGCGTACCATGAATATGCAAAAGAACAAGATGTGACAGTGTATACAATGAAAGATG
TACGAGAGCGAGAAATCAAAGATATTATTATAGAAAGTATTGAAGTATTAAGAAAGCAAGGCGTGACCTCTATTTACATT
TCTCTTGATATGGATGTGCTAGATCAAGCATTTGCACCAGGTTGTCCAGCAATCGGTCCTGGTGGAATGGACAGTACAAC
TTTACTTGATGCGATTGAATTGCTTGGTAACGAACCGCTTGTTCAAGGGATGGATATTGTAGAAATTGATCCAACCCTCG
ATTTTAGAGATATGACGAGTCGAGTAGCTGCGCAAGTGATTATGAGTTTTCTTTTGGCGAGGGAGACAATCCGTAAGCAG
GTTAGTATATAG

Upstream 100 bases:

>100_bases
ATGCTTACAATTATGCTTACGTACCGTATCATTACGGCGTAAGTCATGTAAATACAGTATGGAAGAATGGTAATATCGCA
TATACAAGAGGTGAACAATC

Downstream 100 bases:

>100_bases
GTGTAAAATGAATAGGGGGTATTTACAGATTCTGTATAAAAAACACATTACTACTCATATGTAGTAATGTGTTTTTATGT
AAAAAGAGAAGGTGAAATTA

Product: formimidoylglutamase

Products: NA

Alternate protein names: Formiminoglutamase; Formiminoglutamate hydrolase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MEHGHYLKKNAKFIDREVTKWSEMIKDWEEGVEIFGAALIGAPLSKPSISHSGASFAPKTIRAMLDAYSTYAITEEHDMK
ESVLYDCGDITMHVTNIKESHNRIAKTVGHVTKVNPNMIPIVLGGDHSISFPSITGFANSKGKVGIIQFDAHHDLRNLED
GGPSNGTPFRSLLENDVITGKQLVQIGIRNFSNARAYHEYAKEQDVTVYTMKDVREREIKDIIIESIEVLRKQGVTSIYI
SLDMDVLDQAFAPGCPAIGPGGMDSTTLLDAIELLGNEPLVQGMDIVEIDPTLDFRDMTSRVAAQVIMSFLLARETIRKQ
VSI

Sequences:

>Translated_323_residues
MEHGHYLKKNAKFIDREVTKWSEMIKDWEEGVEIFGAALIGAPLSKPSISHSGASFAPKTIRAMLDAYSTYAITEEHDMK
ESVLYDCGDITMHVTNIKESHNRIAKTVGHVTKVNPNMIPIVLGGDHSISFPSITGFANSKGKVGIIQFDAHHDLRNLED
GGPSNGTPFRSLLENDVITGKQLVQIGIRNFSNARAYHEYAKEQDVTVYTMKDVREREIKDIIIESIEVLRKQGVTSIYI
SLDMDVLDQAFAPGCPAIGPGGMDSTTLLDAIELLGNEPLVQGMDIVEIDPTLDFRDMTSRVAAQVIMSFLLARETIRKQ
VSI
>Mature_323_residues
MEHGHYLKKNAKFIDREVTKWSEMIKDWEEGVEIFGAALIGAPLSKPSISHSGASFAPKTIRAMLDAYSTYAITEEHDMK
ESVLYDCGDITMHVTNIKESHNRIAKTVGHVTKVNPNMIPIVLGGDHSISFPSITGFANSKGKVGIIQFDAHHDLRNLED
GGPSNGTPFRSLLENDVITGKQLVQIGIRNFSNARAYHEYAKEQDVTVYTMKDVREREIKDIIIESIEVLRKQGVTSIYI
SLDMDVLDQAFAPGCPAIGPGGMDSTTLLDAIELLGNEPLVQGMDIVEIDPTLDFRDMTSRVAAQVIMSFLLARETIRKQ
VSI

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=309, Percent_Identity=31.0679611650485, Blast_Score=135, Evalue=5e-32,
Organism=Homo sapiens, GI10947139, Length=319, Percent_Identity=26.3322884012539, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI4502215, Length=313, Percent_Identity=23.3226837060703, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1789306, Length=260, Percent_Identity=27.3076923076923, Blast_Score=96, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24638886, Length=289, Percent_Identity=24.2214532871972, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005923
- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.8 [H]

Molecular weight: Translated: 35760; Mature: 35760

Theoretical pI: Translated: 5.39; Mature: 5.39

Prosite motif: PS00147 ARGINASE_1 ; PS00148 ARGINASE_2 ; PS01053 ARGINASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHGHYLKKNAKFIDREVTKWSEMIKDWEEGVEIFGAALIGAPLSKPSISHSGASFAPKT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
IRAMLDAYSTYAITEEHDMKESVLYDCGDITMHVTNIKESHNRIAKTVGHVTKVNPNMIP
HHHHHHHHHHEEECCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHEECCCCEEE
IVLGGDHSISFPSITGFANSKGKVGIIQFDAHHDLRNLEDGGPSNGTPFRSLLENDVITG
EEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHCCCCCCCCCCCHHHHHHHHCCCCH
KQLVQIGIRNFSNARAYHEYAKEQDVTVYTMKDVREREIKDIIIESIEVLRKQGVTSIYI
HHHHHHHHHCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SLDMDVLDQAFAPGCPAIGPGGMDSTTLLDAIELLGNEPLVQGMDIVEIDPTLDFRDMTS
EECHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHH
RVAAQVIMSFLLARETIRKQVSI
HHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEHGHYLKKNAKFIDREVTKWSEMIKDWEEGVEIFGAALIGAPLSKPSISHSGASFAPKT
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHH
IRAMLDAYSTYAITEEHDMKESVLYDCGDITMHVTNIKESHNRIAKTVGHVTKVNPNMIP
HHHHHHHHHHEEECCHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHEECCCCEEE
IVLGGDHSISFPSITGFANSKGKVGIIQFDAHHDLRNLEDGGPSNGTPFRSLLENDVITG
EEECCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHCCCCCCCCCCCHHHHHHHHCCCCH
KQLVQIGIRNFSNARAYHEYAKEQDVTVYTMKDVREREIKDIIIESIEVLRKQGVTSIYI
HHHHHHHHHCCCCHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEE
SLDMDVLDQAFAPGCPAIGPGGMDSTTLLDAIELLGNEPLVQGMDIVEIDPTLDFRDMTS
EECHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEECCCCCHHHHHH
RVAAQVIMSFLLARETIRKQVSI
HHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]