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The map label for this gene is gudP [H]

Identifier: 49478259

GI number: 49478259

Start: 3332249

End: 3333463

Strand: Reverse

Name: gudP [H]

Synonym: BT9727_3266

Alternate gene names: 49478259

Gene position: 3333463-3332249 (Counterclockwise)

Preceding gene: 49479482

Following gene: 49479259

Centisome position: 63.64

GC content: 34.81

Gene sequence:

>1215_bases
ATGGAAGAAAGGATGAACAGTACTTATAAGTGGGTGATGTTAATTGTTGCGACGATTGCTCAAACAACAGCGACACTTAT
AACATATGGTGTCGGGGTTTTCGCTTTATTTTGGAAAGAAGAATATGCGCTTAAGAATATGGAGAGTGGATTGTTAGTAA
GTGTTGTAAATGTTGGACCGTTATTTTGTATGCTTTTTGTCGGTCGGCTACTTGATCAATATAATGAAAAAATATTAATT
TCTATCAGTTCATTTTTGCTAGGGAGTTCGCTTTTACTGACTAATATAGTAAGTGGATTTAATGGGTTATTATTTGTACT
TTTATTAATAGGAATGTTTTATAGTGTTTCCCAGCCAGGAGGAAGTAAAGTGATTTTAAAATGGTTCCCAAAAGAAAATC
GCGGATTAGCGATGGGGATAAGGCAAGCTGGTATACCGATTGGTGGCGCGTTAGCGGGAGTGTTAATCCCGTTTCTTACA
GTACAATATAATATGACTTACGCGATAAATAGTATCGCATGCATTGGTATAATTGGAGGAGTATTATTTTTTGTGTTTTA
TAAAGAGCCATATGTTCAGGAGGAAGCGAGGGAAGGACATATTAAAATTTCCTTTTGGATGGAGCTAAAAGTAGTGATAT
GTAAAAAAGAGTTGTATCCAATTTATATAACGGGTATTTGCATGATTTCATTACAAATGGTGTTAGTTGGACACTTCATG
AAATTTTTAGCAGGGGAACAACCGATTACATCTATTGTAGCCGGAACAGTATTTTCAGTTATGTTCTTTTCTGGAATGAT
TGGTCGTGTTGCATTAGCAGCTATTAGTGATGTGTTTTATAAGGGGAATCGGCGTATACCTTTATTTATAGCTGTCTGCG
CTTCTATCGGCTTGATTTTATTGTTAGTAATGAGTATACATACAATAACGAGCGGAGTTTTGTATAGTGTAAGTGCATTG
TTAGGATTCTTTTCAATTGGATGGTTTAGTCTTTTTATCGCCGAAGTTGCTGAATCGGCAAGTGAAGAATCTGTTGGAAT
AACAGTTAGTTTGGCACTTACATTCAATCAAATTGCGATTATTGTTGCACCTGTTTTATTTGGTTATATTGTCGATGAGA
AAGGGTATATGTATGCTTGGTTATGTATAGTGCTATTATTAAGTATTTCGGCAGTCAGTTTATATAGAAAAAACAAAAAA
ATAAAAGAAAGTTAG

Upstream 100 bases:

>100_bases
AAAGATATCAATTTTTTTGATGGATTATATGATGAATCTTTATTTTATATGATATCAGAACTTTCATACAATGGAAGAGG
ATGGAGGGATTATTGTGTTA

Downstream 100 bases:

>100_bases
CAATGTAAATTTTTTATGAAGAAAATATAAAGAAATGCCGAGTGAGCGACATTTCTTTTTTTATTTGTTGTATAATCAAA
ATATAAATGAGATTTATTTT

Product: major facilitator family transporter

Products: NA

Alternate protein names: D-glucarate permease [H]

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MEERMNSTYKWVMLIVATIAQTTATLITYGVGVFALFWKEEYALKNMESGLLVSVVNVGPLFCMLFVGRLLDQYNEKILI
SISSFLLGSSLLLTNIVSGFNGLLFVLLLIGMFYSVSQPGGSKVILKWFPKENRGLAMGIRQAGIPIGGALAGVLIPFLT
VQYNMTYAINSIACIGIIGGVLFFVFYKEPYVQEEAREGHIKISFWMELKVVICKKELYPIYITGICMISLQMVLVGHFM
KFLAGEQPITSIVAGTVFSVMFFSGMIGRVALAAISDVFYKGNRRIPLFIAVCASIGLILLLVMSIHTITSGVLYSVSAL
LGFFSIGWFSLFIAEVAESASEESVGITVSLALTFNQIAIIVAPVLFGYIVDEKGYMYAWLCIVLLLSISAVSLYRKNKK
IKES

Sequences:

>Translated_404_residues
MEERMNSTYKWVMLIVATIAQTTATLITYGVGVFALFWKEEYALKNMESGLLVSVVNVGPLFCMLFVGRLLDQYNEKILI
SISSFLLGSSLLLTNIVSGFNGLLFVLLLIGMFYSVSQPGGSKVILKWFPKENRGLAMGIRQAGIPIGGALAGVLIPFLT
VQYNMTYAINSIACIGIIGGVLFFVFYKEPYVQEEAREGHIKISFWMELKVVICKKELYPIYITGICMISLQMVLVGHFM
KFLAGEQPITSIVAGTVFSVMFFSGMIGRVALAAISDVFYKGNRRIPLFIAVCASIGLILLLVMSIHTITSGVLYSVSAL
LGFFSIGWFSLFIAEVAESASEESVGITVSLALTFNQIAIIVAPVLFGYIVDEKGYMYAWLCIVLLLSISAVSLYRKNKK
IKES
>Mature_404_residues
MEERMNSTYKWVMLIVATIAQTTATLITYGVGVFALFWKEEYALKNMESGLLVSVVNVGPLFCMLFVGRLLDQYNEKILI
SISSFLLGSSLLLTNIVSGFNGLLFVLLLIGMFYSVSQPGGSKVILKWFPKENRGLAMGIRQAGIPIGGALAGVLIPFLT
VQYNMTYAINSIACIGIIGGVLFFVFYKEPYVQEEAREGHIKISFWMELKVVICKKELYPIYITGICMISLQMVLVGHFM
KFLAGEQPITSIVAGTVFSVMFFSGMIGRVALAAISDVFYKGNRRIPLFIAVCASIGLILLLVMSIHTITSGVLYSVSAL
LGFFSIGWFSLFIAEVAESASEESVGITVSLALTFNQIAIIVAPVLFGYIVDEKGYMYAWLCIVLLLSISAVSLYRKNKK
IKES

Specific function: Uptake of D-glucarate [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Escherichia coli, GI1789152, Length=413, Percent_Identity=23.4866828087167, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI87082320, Length=387, Percent_Identity=21.1886304909561, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004744
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44457; Mature: 44457

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEERMNSTYKWVMLIVATIAQTTATLITYGVGVFALFWKEEYALKNMESGLLVSVVNVGP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHH
LFCMLFVGRLLDQYNEKILISISSFLLGSSLLLTNIVSGFNGLLFVLLLIGMFYSVSQPG
HHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GSKVILKWFPKENRGLAMGIRQAGIPIGGALAGVLIPFLTVQYNMTYAINSIACIGIIGG
CCEEEEEECCCCCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHH
VLFFVFYKEPYVQEEAREGHIKISFWMELKVVICKKELYPIYITGICMISLQMVLVGHFM
HHHHHHHCCCCHHHHHCCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
KFLAGEQPITSIVAGTVFSVMFFSGMIGRVALAAISDVFYKGNRRIPLFIAVCASIGLIL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LLVMSIHTITSGVLYSVSALLGFFSIGWFSLFIAEVAESASEESVGITVSLALTFNQIAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHH
IVAPVLFGYIVDEKGYMYAWLCIVLLLSISAVSLYRKNKKIKES
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MEERMNSTYKWVMLIVATIAQTTATLITYGVGVFALFWKEEYALKNMESGLLVSVVNVGP
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHH
LFCMLFVGRLLDQYNEKILISISSFLLGSSLLLTNIVSGFNGLLFVLLLIGMFYSVSQPG
HHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
GSKVILKWFPKENRGLAMGIRQAGIPIGGALAGVLIPFLTVQYNMTYAINSIACIGIIGG
CCEEEEEECCCCCCCCEEEHHHCCCCCHHHHHHHHHHHHHHHEEEEEHHHHHHHHHHHHH
VLFFVFYKEPYVQEEAREGHIKISFWMELKVVICKKELYPIYITGICMISLQMVLVGHFM
HHHHHHHCCCCHHHHHCCCCEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHH
KFLAGEQPITSIVAGTVFSVMFFSGMIGRVALAAISDVFYKGNRRIPLFIAVCASIGLIL
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LLVMSIHTITSGVLYSVSALLGFFSIGWFSLFIAEVAESASEESVGITVSLALTFNQIAI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEHHHHHHH
IVAPVLFGYIVDEKGYMYAWLCIVLLLSISAVSLYRKNKKIKES
HHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7704254; 9384377 [H]