Click here to switch to the map view.

The map label for this gene is murG

Identifier: 161761253

GI number: 161761253

Start: 3750435

End: 3751529

Strand: Reverse

Name: murG

Synonym: BT9727_3652

Alternate gene names: 161761253

Gene position: 3751529-3750435 (Counterclockwise)

Preceding gene: 49478445

Following gene: 49479405

Centisome position: 71.63

GC content: 36.8

Gene sequence:

>1095_bases
GTGCGTGTATTAGTAAGTGGTGGGGGCACTGGAGGTCATATTTATCCGGCTCTTGCTTTAATAAGAGAAATAAAAAAATT
AAATCCGGAAGCAAGGTTTTTATATATTGGCACGGAAAATGGATTAGAGAGTACAATCGTGCCAAAAACAGGTATACCGT
TTCAATCTATTGTTATAAGTGGATTTAAGCGTAAAATATCGTTAGATAACGTGAAAACGGTGATGCGTTTCCTAAAAGGT
GTACAAGACAGTAAACGATATATTCGTCGTTTTAATCCAGATATTGTAATTGGAACGGGTGGATATGTATGTGGACCTGT
TGTATATGCTGCGGCAAAATTAGGTATTCCAACTATTGTACATGAACAAAATAGTGTACCTGGTGTAACGAATAAATTTT
TAAGTCGCTACGTTGATAAAGTTGCAGTTTGTTTTGAAGCGGCTGCAGAACATTTTCCACAGTCAAAAGTGGTCATGACA
GGAAATCCACGAGCGTCAGAAGTAATGGATCAAAATGGAATGAAAGGAAAACGTTCAGTAGGTTTATCCCTTCCTAAAAA
ATCCGTGCTTATTTTTGGTGGAAGCCGTGGGGCCAGACCAATTAACGATGCTTTCGTAGAGGCAATTGAACAGTTTGGAA
ATAAAAGTTACGAAATATTGTATGTAACAGGTGAAGTTCATTATGACAAAGTGATGGAAGCAGTGAAGCAAAAAGGGAAT
CCGAATAATGTTATTATTAAACCTTTCATTCATAATATGCCAGAAGTACTTACAGGTGTAGATCTTGTTGTTTCAAGAGC
TGGGGCAACAACACTTGCAGAATTAACAGCGTTAGGTAAGCCAAGTGTGTTAATTCCGAGTCCGTATGTAACAAATAACC
ATCAGGAAAAAAATGCACGTTCTGTTGTCGATAAAGGAGCAGCAAAAATGTTGCTTGAAAAAGATTTAACAGCTGAAACA
CTTATTCGTGATATTGATGAGATTCTATTAGATGCACAAACATTACAAAATATGAAGCTTGCTGCTGGGCAATTAGGTAT
TCCAGATGCAGCAAATAAGCTGTATGAAGTCATGAATAAGCTTGTAAAAAAATAA

Upstream 100 bases:

>100_bases
GTTTTATAAGACAGGGTTTTTCGTATGTGCGTGAAGAAACAATATGTATATAGAAATAAATACGACTGAAATAAGAAAAA
GAGAAGCGGAGGAGTTAGTA

Downstream 100 bases:

>100_bases
CGTTAGGTGAACGCCCTGCATACTACTGTAATAAGGATGCTGAGTATGGGGGAGATTGTTTATGGAGCAATTAGTAAATG
AGCTTATAGAAGCAAATGTT

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase 1 [H]

Number of amino acids: Translated: 364; Mature: 364

Protein sequence:

>364_residues
MRVLVSGGGTGGHIYPALALIREIKKLNPEARFLYIGTENGLESTIVPKTGIPFQSIVISGFKRKISLDNVKTVMRFLKG
VQDSKRYIRRFNPDIVIGTGGYVCGPVVYAAAKLGIPTIVHEQNSVPGVTNKFLSRYVDKVAVCFEAAAEHFPQSKVVMT
GNPRASEVMDQNGMKGKRSVGLSLPKKSVLIFGGSRGARPINDAFVEAIEQFGNKSYEILYVTGEVHYDKVMEAVKQKGN
PNNVIIKPFIHNMPEVLTGVDLVVSRAGATTLAELTALGKPSVLIPSPYVTNNHQEKNARSVVDKGAAKMLLEKDLTAET
LIRDIDEILLDAQTLQNMKLAAGQLGIPDAANKLYEVMNKLVKK

Sequences:

>Translated_364_residues
MRVLVSGGGTGGHIYPALALIREIKKLNPEARFLYIGTENGLESTIVPKTGIPFQSIVISGFKRKISLDNVKTVMRFLKG
VQDSKRYIRRFNPDIVIGTGGYVCGPVVYAAAKLGIPTIVHEQNSVPGVTNKFLSRYVDKVAVCFEAAAEHFPQSKVVMT
GNPRASEVMDQNGMKGKRSVGLSLPKKSVLIFGGSRGARPINDAFVEAIEQFGNKSYEILYVTGEVHYDKVMEAVKQKGN
PNNVIIKPFIHNMPEVLTGVDLVVSRAGATTLAELTALGKPSVLIPSPYVTNNHQEKNARSVVDKGAAKMLLEKDLTAET
LIRDIDEILLDAQTLQNMKLAAGQLGIPDAANKLYEVMNKLVKK
>Mature_364_residues
MRVLVSGGGTGGHIYPALALIREIKKLNPEARFLYIGTENGLESTIVPKTGIPFQSIVISGFKRKISLDNVKTVMRFLKG
VQDSKRYIRRFNPDIVIGTGGYVCGPVVYAAAKLGIPTIVHEQNSVPGVTNKFLSRYVDKVAVCFEAAAEHFPQSKVVMT
GNPRASEVMDQNGMKGKRSVGLSLPKKSVLIFGGSRGARPINDAFVEAIEQFGNKSYEILYVTGEVHYDKVMEAVKQKGN
PNNVIIKPFIHNMPEVLTGVDLVVSRAGATTLAELTALGKPSVLIPSPYVTNNHQEKNARSVVDKGAAKMLLEKDLTAET
LIRDIDEILLDAQTLQNMKLAAGQLGIPDAANKLYEVMNKLVKK

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=362, Percent_Identity=31.767955801105, Blast_Score=182, Evalue=3e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 39631; Mature: 39631

Theoretical pI: Translated: 10.06; Mature: 10.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLVSGGGTGGHIYPALALIREIKKLNPEARFLYIGTENGLESTIVPKTGIPFQSIVIS
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHH
GFKRKISLDNVKTVMRFLKGVQDSKRYIRRFNPDIVIGTGGYVCGPVVYAAAKLGIPTIV
HHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCEEE
HEQNSVPGVTNKFLSRYVDKVAVCFEAAAEHFPQSKVVMTGNPRASEVMDQNGMKGKRSV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCCCCC
GLSLPKKSVLIFGGSRGARPINDAFVEAIEQFGNKSYEILYVTGEVHYDKVMEAVKQKGN
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCC
PNNVIIKPFIHNMPEVLTGVDLVVSRAGATTLAELTALGKPSVLIPSPYVTNNHQEKNAR
CCCEEEEHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEECCCCCCCCCCCHHHHH
SVVDKGAAKMLLEKDLTAETLIRDIDEILLDAQTLQNMKLAAGQLGIPDAANKLYEVMNK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LVKK
HHCC
>Mature Secondary Structure
MRVLVSGGGTGGHIYPALALIREIKKLNPEARFLYIGTENGLESTIVPKTGIPFQSIVIS
CEEEEECCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHHHH
GFKRKISLDNVKTVMRFLKGVQDSKRYIRRFNPDIVIGTGGYVCGPVVYAAAKLGIPTIV
HHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHCCCEEE
HEQNSVPGVTNKFLSRYVDKVAVCFEAAAEHFPQSKVVMTGNPRASEVMDQNGMKGKRSV
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHCCCCCCCCCC
GLSLPKKSVLIFGGSRGARPINDAFVEAIEQFGNKSYEILYVTGEVHYDKVMEAVKQKGN
CCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHCCC
PNNVIIKPFIHNMPEVLTGVDLVVSRAGATTLAELTALGKPSVLIPSPYVTNNHQEKNAR
CCCEEEEHHHHCHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEECCCCCCCCCCCHHHHH
SVVDKGAAKMLLEKDLTAETLIRDIDEILLDAQTLQNMKLAAGQLGIPDAANKLYEVMNK
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
LVKK
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12721629 [H]