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The map label for this gene is fbaB

Identifier: 49476163

GI number: 49476163

Start: 1726949

End: 1727980

Strand: Reverse

Name: fbaB

Synonym: BH15060

Alternate gene names: NA

Gene position: 1727980-1726949 (Counterclockwise)

Preceding gene: 49476164

Following gene: 49476161

Centisome position: 89.48

GC content: 44.86

Gene sequence:

>1032_bases
ATGAATGAACGTCTGGAAGATATAGCACTTACTCTGGTAGGTGCGGGTAAAGGTATTTTGGCAGCAGATGAAAGTACTGC
AACGATTGGAAAGCGTTTTGAAAGCATTGGGGTGGAATGCACCGAAGATAATCGTCGCGCCTATCGTGAAATGCTGTTTA
CTGCAAAAGAAGCCATGGAAAGCGCTATCTCTGGTGTCATCTTATTTGATGAAACACTGCGTCAAAAAGCATCTACAGGG
CAGATGTTGACAGATCTTATTCGTGATGCAGGTGCTGTGCCGGGGATCAAAGTCGATACCGGTGCCAAACCATTGGCGGC
TTTTCCTCAAGAAACGATTACAGAAGGCTTGGATGGTCTTCGTGAGCGTTTAAAGGATTATTATACTTTGGGAGCCCGTT
TTGCTAAATGGCGCGCGGTCATTGCCATTGATGCACAGACTCTCCCAACAAGAGGGGCAATCAGTCAGAATGCACAAGCT
CTCGCGCGTTATGCTGCTTTATGTCAGGAAGCTGGTCTTGTACCGATTGTTGAACCGGAAGTGCTGATGGATGGACCATC
ACGCCAGCATTCTATTACGCGTTGCTTTGAGGTGACAAAAGTTGTTTTACACACTGTGTTTAAAGAATTATTTGAGGCAC
GTGTTCTTTTCGAGGGCATGATTTTAAAACCCAATATGGTGATTGATGGAAAAGATGCGCGCATTGCTTCTGTGGAAGAA
GTAGCTGAAAAGACAGTTCATGTTCTTAAACAGACTGTTCCTGCTGCTGTTCCAGGAATTGCTTTTCTTTCTGGAGGACA
AACTGATGAAGAAGCTACGGCACATTTGTCGGCTATGAATGCTTTGGGAGCATTGCCTTGGAAATTGACCTTTTCTTATG
GGCGGGCATTGCAAGCAGCTGCCTTAAAGGCATGGGCTGGAAAAAATGAAAATATTGTTGTTGCGCAAAAGGCTTTTTGT
CATCGTGCTCGAATGAACCACCTTGCTGCTTTGGGACAATGGACAAAAGATCAGGAAAAATCTTGTGCTTAA

Upstream 100 bases:

>100_bases
CATTTGAACAAACAGTTAAAAAAAAGCTGTATGATTATGGAGGGTGTGCTGGTGCATTGCACGCTTTTGGAAATTAAGAC
AGGATAAAGAGGAATTTTTT

Downstream 100 bases:

>100_bases
AAAACAATAAAATGTTGCTTCAATATAGTTAAGATTTTGGTTTTTAAGTGTGAAATGTAAATCTTATGCTGTATCAAACT
GTTGAAGGGCGCAATATTCT

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MNERLEDIALTLVGAGKGILAADESTATIGKRFESIGVECTEDNRRAYREMLFTAKEAMESAISGVILFDETLRQKASTG
QMLTDLIRDAGAVPGIKVDTGAKPLAAFPQETITEGLDGLRERLKDYYTLGARFAKWRAVIAIDAQTLPTRGAISQNAQA
LARYAALCQEAGLVPIVEPEVLMDGPSRQHSITRCFEVTKVVLHTVFKELFEARVLFEGMILKPNMVIDGKDARIASVEE
VAEKTVHVLKQTVPAAVPGIAFLSGGQTDEEATAHLSAMNALGALPWKLTFSYGRALQAAALKAWAGKNENIVVAQKAFC
HRARMNHLAALGQWTKDQEKSCA

Sequences:

>Translated_343_residues
MNERLEDIALTLVGAGKGILAADESTATIGKRFESIGVECTEDNRRAYREMLFTAKEAMESAISGVILFDETLRQKASTG
QMLTDLIRDAGAVPGIKVDTGAKPLAAFPQETITEGLDGLRERLKDYYTLGARFAKWRAVIAIDAQTLPTRGAISQNAQA
LARYAALCQEAGLVPIVEPEVLMDGPSRQHSITRCFEVTKVVLHTVFKELFEARVLFEGMILKPNMVIDGKDARIASVEE
VAEKTVHVLKQTVPAAVPGIAFLSGGQTDEEATAHLSAMNALGALPWKLTFSYGRALQAAALKAWAGKNENIVVAQKAFC
HRARMNHLAALGQWTKDQEKSCA
>Mature_343_residues
MNERLEDIALTLVGAGKGILAADESTATIGKRFESIGVECTEDNRRAYREMLFTAKEAMESAISGVILFDETLRQKASTG
QMLTDLIRDAGAVPGIKVDTGAKPLAAFPQETITEGLDGLRERLKDYYTLGARFAKWRAVIAIDAQTLPTRGAISQNAQA
LARYAALCQEAGLVPIVEPEVLMDGPSRQHSITRCFEVTKVVLHTVFKELFEARVLFEGMILKPNMVIDGKDARIASVEE
VAEKTVHVLKQTVPAAVPGIAFLSGGQTDEEATAHLSAMNALGALPWKLTFSYGRALQAAALKAWAGKNENIVVAQKAFC
HRARMNHLAALGQWTKDQEKSCA

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI34577112, Length=335, Percent_Identity=53.4328358208955, Blast_Score=332, Evalue=3e-91,
Organism=Homo sapiens, GI34577110, Length=335, Percent_Identity=53.4328358208955, Blast_Score=332, Evalue=3e-91,
Organism=Homo sapiens, GI4557305, Length=335, Percent_Identity=53.4328358208955, Blast_Score=332, Evalue=3e-91,
Organism=Homo sapiens, GI193794814, Length=335, Percent_Identity=53.4328358208955, Blast_Score=332, Evalue=3e-91,
Organism=Homo sapiens, GI4885063, Length=334, Percent_Identity=52.0958083832335, Blast_Score=322, Evalue=3e-88,
Organism=Homo sapiens, GI40354205, Length=335, Percent_Identity=51.6417910447761, Blast_Score=318, Evalue=5e-87,
Organism=Caenorhabditis elegans, GI25150450, Length=336, Percent_Identity=49.702380952381, Blast_Score=321, Evalue=3e-88,
Organism=Caenorhabditis elegans, GI71983985, Length=335, Percent_Identity=52.2388059701493, Blast_Score=321, Evalue=4e-88,
Organism=Caenorhabditis elegans, GI71983990, Length=231, Percent_Identity=49.3506493506493, Blast_Score=212, Evalue=2e-55,
Organism=Drosophila melanogaster, GI221459619, Length=336, Percent_Identity=51.1904761904762, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24650288, Length=336, Percent_Identity=51.1904761904762, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24650282, Length=335, Percent_Identity=51.044776119403, Blast_Score=324, Evalue=5e-89,
Organism=Drosophila melanogaster, GI24650280, Length=335, Percent_Identity=51.044776119403, Blast_Score=324, Evalue=5e-89,
Organism=Drosophila melanogaster, GI24650278, Length=335, Percent_Identity=51.044776119403, Blast_Score=324, Evalue=5e-89,
Organism=Drosophila melanogaster, GI45553577, Length=335, Percent_Identity=50.7462686567164, Blast_Score=322, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24650304, Length=336, Percent_Identity=43.75, Blast_Score=276, Evalue=1e-74,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 37212; Mature: 37212

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNERLEDIALTLVGAGKGILAADESTATIGKRFESIGVECTEDNRRAYREMLFTAKEAME
CCCHHHHHHHHEEECCCCEEECCCCHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHH
SAISGVILFDETLRQKASTGQMLTDLIRDAGAVPGIKVDTGAKPLAAFPQETITEGLDGL
HHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHCCHHHHHHHHHHH
RERLKDYYTLGARFAKWRAVIAIDAQTLPTRGAISQNAQALARYAALCQEAGLVPIVEPE
HHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCH
VLMDGPSRQHSITRCFEVTKVVLHTVFKELFEARVLFEGMILKPNMVIDGKDARIASVEE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCEEECCCCCCHHHHHH
VAEKTVHVLKQTVPAAVPGIAFLSGGQTDEEATAHLSAMNALGALPWKLTFSYGRALQAA
HHHHHHHHHHHHHHHHCCCHHEECCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
ALKAWAGKNENIVVAQKAFCHRARMNHLAALGQWTKDQEKSCA
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHCCCC
>Mature Secondary Structure
MNERLEDIALTLVGAGKGILAADESTATIGKRFESIGVECTEDNRRAYREMLFTAKEAME
CCCHHHHHHHHEEECCCCEEECCCCHHHHHHHHHHCCCEECCHHHHHHHHHHHHHHHHHH
SAISGVILFDETLRQKASTGQMLTDLIRDAGAVPGIKVDTGAKPLAAFPQETITEGLDGL
HHHCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCHHHCCHHHHHHHHHHH
RERLKDYYTLGARFAKWRAVIAIDAQTLPTRGAISQNAQALARYAALCQEAGLVPIVEPE
HHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEECCCH
VLMDGPSRQHSITRCFEVTKVVLHTVFKELFEARVLFEGMILKPNMVIDGKDARIASVEE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEECCCEEECCCCCCHHHHHH
VAEKTVHVLKQTVPAAVPGIAFLSGGQTDEEATAHLSAMNALGALPWKLTFSYGRALQAA
HHHHHHHHHHHHHHHHCCCHHEECCCCCCHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHH
ALKAWAGKNENIVVAQKAFCHRARMNHLAALGQWTKDQEKSCA
HHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12024217 [H]