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The map label for this gene is exbB [H]

Identifier: 49476130

GI number: 49476130

Start: 1688248

End: 1689090

Strand: Reverse

Name: exbB [H]

Synonym: BH14710

Alternate gene names: 49476130

Gene position: 1689090-1688248 (Counterclockwise)

Preceding gene: 49476133

Following gene: 49476129

Centisome position: 87.47

GC content: 45.31

Gene sequence:

>843_bases
ATGGAATCTGAAACAATACCTTTAGACACTCCACCTGCTGTATTTGCAGCGCATGATCTTTCTCCTTTTTCTATGTTTAT
GGCCGCTGATTTTGTGGTGAAAGCCGTTATTGTGTTGTTGTTGCTGGCTTCTCTGGCATCTTGGACAATTGCTTTTGTAA
AGATCATTGAAATTACCTTGGCAAAACGAAAAGCACGTCATGAACTGCGCTTGGTTCTTAGCGCTCAAACTCTGACACGT
TTGGCTGCTAGCTTGAAAGACAGCAAAGGACCTGGTGTGTTTTTTTTTAAAGAAATGCTTAAAGAGGTGTATCTTTCCAC
GCAAAAGGTCAACTTTATTGCAACGGAGGATTCCAGTGAAAGACAAGGGGAACAAACGGTTGTCTGTGAAGATGCTATCC
CCTATGCAGAGATTGCGCGATATGGAGAGACTGCTCGTGGTGTTAATGAGGGCTTGAAGGAGCGTGTGCATTCACTTTTG
TCGCGTTGCTTACTGGCTGCTACACGCCGTGTTGCATGTGGGAGCGCTGTTCTTGCAACTATTGGTGCTATTGCTCCCTT
CGTTGGTCTTTTTGCAACCGTTTGGGGGATCATGAATTCTTTCATCGGAATTGCTCAATCGCAAACAACACGGCTTGATG
TCGTCGCTCCTGGAATTGCCGAAGCCTTGCTTGCAACGGCTATCGGCCTTTTTGTGGCTATTCCCGCTGTTGTTATGTAT
AATAGCCTGATGCGTGCTTTGAGCGGTTATCGCAATGATTTGGGTGATATCGCTGCTGCACTTGAGAGACTCTTGAGCCG
TGAACTCGATCGATATAGACAACAGAAAAGTCATAAACAATGA

Upstream 100 bases:

>100_bases
AAATGGTATTGTGGCAAAGTGATGCTACGCCGGGTGATGGTACAGCTGTAAGATCAAAAAGTGAAAACCACAATGAAAAC
CACAATAATGTGAGACAAAA

Downstream 100 bases:

>100_bases
AAGCAAACTTTAATGAAGATTGGGATCTCGATGAGAGTGGGTTGCACAACGAGATCAATGTTACCCCTTTCATTGATGTC
GTTTTAGTGTTGCTTATTGT

Product: biopolymer transport exbB protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MESETIPLDTPPAVFAAHDLSPFSMFMAADFVVKAVIVLLLLASLASWTIAFVKIIEITLAKRKARHELRLVLSAQTLTR
LAASLKDSKGPGVFFFKEMLKEVYLSTQKVNFIATEDSSERQGEQTVVCEDAIPYAEIARYGETARGVNEGLKERVHSLL
SRCLLAATRRVACGSAVLATIGAIAPFVGLFATVWGIMNSFIGIAQSQTTRLDVVAPGIAEALLATAIGLFVAIPAVVMY
NSLMRALSGYRNDLGDIAAALERLLSRELDRYRQQKSHKQ

Sequences:

>Translated_280_residues
MESETIPLDTPPAVFAAHDLSPFSMFMAADFVVKAVIVLLLLASLASWTIAFVKIIEITLAKRKARHELRLVLSAQTLTR
LAASLKDSKGPGVFFFKEMLKEVYLSTQKVNFIATEDSSERQGEQTVVCEDAIPYAEIARYGETARGVNEGLKERVHSLL
SRCLLAATRRVACGSAVLATIGAIAPFVGLFATVWGIMNSFIGIAQSQTTRLDVVAPGIAEALLATAIGLFVAIPAVVMY
NSLMRALSGYRNDLGDIAAALERLLSRELDRYRQQKSHKQ
>Mature_280_residues
MESETIPLDTPPAVFAAHDLSPFSMFMAADFVVKAVIVLLLLASLASWTIAFVKIIEITLAKRKARHELRLVLSAQTLTR
LAASLKDSKGPGVFFFKEMLKEVYLSTQKVNFIATEDSSERQGEQTVVCEDAIPYAEIARYGETARGVNEGLKERVHSLL
SRCLLAATRRVACGSAVLATIGAIAPFVGLFATVWGIMNSFIGIAQSQTTRLDVVAPGIAEALLATAIGLFVAIPAVVMY
NSLMRALSGYRNDLGDIAAALERLLSRELDRYRQQKSHKQ

Specific function: Involved in the tonB-dependent energy-dependent transport of various receptor-bound substrates. Protects exbD from proteolytic degradation and functionally stabilizes tonB [H]

COG id: COG0811

COG function: function code U; Biopolymer transport proteins

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the exbB/tolQ family [H]

Homologues:

Organism=Escherichia coli, GI1789381, Length=262, Percent_Identity=43.5114503816794, Blast_Score=184, Evalue=6e-48,
Organism=Escherichia coli, GI1786958, Length=249, Percent_Identity=29.718875502008, Blast_Score=95, Evalue=5e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002898
- InterPro:   IPR014164 [H]

Pfam domain/function: PF01618 MotA_ExbB [H]

EC number: NA

Molecular weight: Translated: 30504; Mature: 30504

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESETIPLDTPPAVFAAHDLSPFSMFMAADFVVKAVIVLLLLASLASWTIAFVKIIEITL
CCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKRKARHELRLVLSAQTLTRLAASLKDSKGPGVFFFKEMLKEVYLSTQKVNFIATEDSSE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCC
RQGEQTVVCEDAIPYAEIARYGETARGVNEGLKERVHSLLSRCLLAATRRVACGSAVLAT
CCCCCEEEECCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGAIAPFVGLFATVWGIMNSFIGIAQSQTTRLDVVAPGIAEALLATAIGLFVAIPAVVMY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHHHH
NSLMRALSGYRNDLGDIAAALERLLSRELDRYRQQKSHKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MESETIPLDTPPAVFAAHDLSPFSMFMAADFVVKAVIVLLLLASLASWTIAFVKIIEITL
CCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AKRKARHELRLVLSAQTLTRLAASLKDSKGPGVFFFKEMLKEVYLSTQKVNFIATEDSSE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHEEEEECCCCCC
RQGEQTVVCEDAIPYAEIARYGETARGVNEGLKERVHSLLSRCLLAATRRVACGSAVLAT
CCCCCEEEECCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGAIAPFVGLFATVWGIMNSFIGIAQSQTTRLDVVAPGIAEALLATAIGLFVAIPAVVMY
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHCCCHHHHHHHHHHHHHHHHHHHHHHH
NSLMRALSGYRNDLGDIAAALERLLSRELDRYRQQKSHKQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8437515 [H]