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The map label for this gene is groES [H]

Identifier: 49476035

GI number: 49476035

Start: 1549332

End: 1549628

Strand: Reverse

Name: groES [H]

Synonym: BH13540

Alternate gene names: 49476035

Gene position: 1549628-1549332 (Counterclockwise)

Preceding gene: 49476037

Following gene: 49476034

Centisome position: 80.25

GC content: 43.43

Gene sequence:

>297_bases
ATGGCTAACATACAATTCCGCCCACTTCACGATCGTGTTGTTGTCCGTCGGGTTGAATCTGAAAATAAAACTGCTGGTGG
GATTATCATCCCCGATACAGCGAAGGAAAAACCTCAAGAAGGTGAAGTTATCGCTGTTGGTAATGGAGCTCTCGATGACA
ATGGGAAGCGTGTGCCTTTAGAAGTAAAAACAGGGGACCGTATCTTGTTTGGAAAATGGTCTGGAACCGAAGTGAAGATT
AATGGGGAAGACCTTTTAATCATGAAAGAGTCTGACATTATGGGGATTTTGGGTTAA

Upstream 100 bases:

>100_bases
GGCAATTTTATATTCCAGTCATTGTTAGCACTCTTTCTTAAAGAGCGCTAACAAAGACTTAAGATTAATTCATTTATATT
AAATTTTAAGGATTTAAAAT

Downstream 100 bases:

>100_bases
TCCAACCTCTCAATTTTTTTCATTTTCTACTATTTAGGACATAACTCCAAGGAGAAATTAAATGGCTGCTAAAGAAGTCA
AGTTTGGCCGTGAAGCGCGT

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 98; Mature: 97

Protein sequence:

>98_residues
MANIQFRPLHDRVVVRRVESENKTAGGIIIPDTAKEKPQEGEVIAVGNGALDDNGKRVPLEVKTGDRILFGKWSGTEVKI
NGEDLLIMKESDIMGILG

Sequences:

>Translated_98_residues
MANIQFRPLHDRVVVRRVESENKTAGGIIIPDTAKEKPQEGEVIAVGNGALDDNGKRVPLEVKTGDRILFGKWSGTEVKI
NGEDLLIMKESDIMGILG
>Mature_97_residues
ANIQFRPLHDRVVVRRVESENKTAGGIIIPDTAKEKPQEGEVIAVGNGALDDNGKRVPLEVKTGDRILFGKWSGTEVKIN
GEDLLIMKESDIMGILG

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI4504523, Length=91, Percent_Identity=37.3626373626374, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1790585, Length=95, Percent_Identity=49.4736842105263, Blast_Score=92, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI17555568, Length=92, Percent_Identity=41.304347826087, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324594, Length=89, Percent_Identity=37.0786516853933, Blast_Score=73, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21356029, Length=93, Percent_Identity=40.8602150537634, Blast_Score=73, Evalue=4e-14,
Organism=Drosophila melanogaster, GI21358317, Length=101, Percent_Identity=36.6336633663366, Blast_Score=66, Evalue=5e-12,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 10696; Mature: 10565

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANIQFRPLHDRVVVRRVESENKTAGGIIIPDTAKEKPQEGEVIAVGNGALDDNGKRVPL
CCCCEEEECCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEE
EVKTGDRILFGKWSGTEVKINGEDLLIMKESDIMGILG
EECCCCEEEEECCCCCEEEECCCEEEEEECCCEEEECC
>Mature Secondary Structure 
ANIQFRPLHDRVVVRRVESENKTAGGIIIPDTAKEKPQEGEVIAVGNGALDDNGKRVPL
CCCEEEECCCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCEEEEECCCCCCCCCEEEE
EVKTGDRILFGKWSGTEVKINGEDLLIMKESDIMGILG
EECCCCEEEEECCCCCEEEECCCEEEEEECCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA