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The map label for this gene is slt [C]

Identifier: 49475864

GI number: 49475864

Start: 1251330

End: 1251839

Strand: Reverse

Name: slt [C]

Synonym: BH11350

Alternate gene names: 49475864

Gene position: 1251839-1251330 (Counterclockwise)

Preceding gene: 49475865

Following gene: 49475863

Centisome position: 64.83

GC content: 36.08

Gene sequence:

>510_bases
ATGCAATTTTTGAAAATTCTTTTAAGTGCAGTATTTGCTATATCTTTTGTGTTTGATATAAGTTTGGCTCATACCGTGTT
AAATGTTGCAGGGTCAAGTGAAGGCTCAGAGATTATTGCTTCTAAGATTCCTGTTCGTCCTTATGAGTTTCTTATTCAGA
AATTTGCGAATAAGTACAATGTTCCTGTTAATTTGGCACATGCTGTTGTAAGAGTTGAAAGTGATTATAAGGCCTTTATA
AAAGGGGCGGCTGGTGAAATAGGTTTGATGCAAATTAAACCTTCTACGGCACGAGGATTGGGTTTTAAGGGATCAGTGCA
AGATCTGTATGATCCTGCGACTAATCTTGAATATGGTATGCGTTATTTGGCGCGGGCATATAAACTAAGTGCTGGTGATA
CGTGTGGCACAATCCTTAAATATAATGCAGGTCATGCTGCAAAAAAAATGAATTCCATTTCAGAAAAATATTGCTCAAAA
GTAAAAACTTATCTGGCTTCTTTAAAATGA

Upstream 100 bases:

>100_bases
TTTCATTTTCAAGCCGCTCTTTCGTTTTTTTTCTATGTACAATGCGCCCACCAAGCCGTTGCAGCTAGGATTTAAGAATG
TCTTAATGAAGAGAAAGAAA

Downstream 100 bases:

>100_bases
AGATGTACCATTAAAAGCAATGTTTTTTTTCAGATTTGTAAAATATATTGCAGGACTCTTTTCACTTGACCAAAAATGTT
TTATAAATAAAGTATCAGTC

Product: transmembrane protein

Products: 1,6-Anhydrobond [C]

Alternate protein names: Transglycosylase; Lytic Murein Transglycosylase; Transglycosylase Protein; Lytic Transglycosylase; Soluble Lytic Transglycosylase; Soluble Lytic Murein Transglycosylase; Transmembrane Protein; Transglycosylase Slt Family; Transglycosylase SLT Domain; Transglycosylase SLT Domain-Containing Protein; Transglycosylase SLT Domain Protein

Number of amino acids: Translated: 169; Mature: 169

Protein sequence:

>169_residues
MQFLKILLSAVFAISFVFDISLAHTVLNVAGSSEGSEIIASKIPVRPYEFLIQKFANKYNVPVNLAHAVVRVESDYKAFI
KGAAGEIGLMQIKPSTARGLGFKGSVQDLYDPATNLEYGMRYLARAYKLSAGDTCGTILKYNAGHAAKKMNSISEKYCSK
VKTYLASLK

Sequences:

>Translated_169_residues
MQFLKILLSAVFAISFVFDISLAHTVLNVAGSSEGSEIIASKIPVRPYEFLIQKFANKYNVPVNLAHAVVRVESDYKAFI
KGAAGEIGLMQIKPSTARGLGFKGSVQDLYDPATNLEYGMRYLARAYKLSAGDTCGTILKYNAGHAAKKMNSISEKYCSK
VKTYLASLK
>Mature_169_residues
MQFLKILLSAVFAISFVFDISLAHTVLNVAGSSEGSEIIASKIPVRPYEFLIQKFANKYNVPVNLAHAVVRVESDYKAFI
KGAAGEIGLMQIKPSTARGLGFKGSVQDLYDPATNLEYGMRYLARAYKLSAGDTCGTILKYNAGHAAKKMNSISEKYCSK
VKTYLASLK

Specific function: Murein-Degrading Enzyme. Catalyzes The Cleavage Of The Glycosidic Bonds Between N-Acetylmuramic Acid And N- Acetylglucosamine Residues In Peptidoglycan. May Play A Role In Recycling Of Muropeptides During Cell Elongation And/Or Cell Division. [C]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Periplasmic Protein. Tightly Associated With The Murein Sacculus [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 3.2.1.- [C]

Molecular weight: Translated: 18455; Mature: 18455

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFLKILLSAVFAISFVFDISLAHTVLNVAGSSEGSEIIASKIPVRPYEFLIQKFANKYN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHCC
VPVNLAHAVVRVESDYKAFIKGAAGEIGLMQIKPSTARGLGFKGSVQDLYDPATNLEYGM
CCHHHHHHHHHHCCHHHHHHHCCCCCEEEEEECCCHHCCCCCCCCHHHHHCCCCCHHHHH
RYLARAYKLSAGDTCGTILKYNAGHAAKKMNSISEKYCSKVKTYLASLK
HHHHHHHHCCCCCCCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQFLKILLSAVFAISFVFDISLAHTVLNVAGSSEGSEIIASKIPVRPYEFLIQKFANKYN
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCHHHHHHHHHHHHCC
VPVNLAHAVVRVESDYKAFIKGAAGEIGLMQIKPSTARGLGFKGSVQDLYDPATNLEYGM
CCHHHHHHHHHHCCHHHHHHHCCCCCEEEEEECCCHHCCCCCCCCHHHHHCCCCCHHHHH
RYLARAYKLSAGDTCGTILKYNAGHAAKKMNSISEKYCSKVKTYLASLK
HHHHHHHHCCCCCCCCHHEEECCCHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid Residue (N-Acetylmuramic Acid And N-Acetylglucosamine Residues) [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA