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The map label for this gene is nuoL [H]

Identifier: 49475647

GI number: 49475647

Start: 999470

End: 1001434

Strand: Reverse

Name: nuoL [H]

Synonym: BH08840

Alternate gene names: 49475647

Gene position: 1001434-999470 (Counterclockwise)

Preceding gene: 49475648

Following gene: 49475646

Centisome position: 51.86

GC content: 37.4

Gene sequence:

>1965_bases
ATGTATTATACGATCGTCTTTCTTCCGCTTTTGGGTTTTTTAATTGCTGCTATAGCTGGAAAAACTATAGGAGATCGGGC
GAGTGAATTGGTTACATGTAGCTTTATGGTGATTGTTGCCACACTGTCATGGGTAGCATTTTTTAATATTGCATTTGGTC
ATACTCCAGTGGTTGATGTATTGGTATTGCATTGGCTCGATGTTGGCAGTCTAAGTTTTAGCTGGGCTTTACATATTGAT
ACATTAACATCTGTTATGCTTATTGTTGTTAACAGTGTTTCAGCATTAGTGCATATTTATTCAATTGGTTATATGCACCA
TGATCCTTCAAGACCTCGTTTTTTTTCTTATCTTTCTCTCTTTACATTTATGATGCTTATGTTGGTGACATCCAATAATT
TATTGCAAATGTTTTTTGGCTGGGAAGGTGTAGGGCTTGCTTCTTATTTGCTCATTGGTTTTTGGTTTCAGCGAGATTCT
GCAAATAAGGCTGCAATGAAGGCTTTTGTAGTTAATCGTGTTGGAGATTTTGGTTTTCTCTTAGGAATTTTTAGTATTTT
TGTTTTATTCCAATCTGTTGATTTTACCTCTATTTTTGCAAAAGCTGCAGACAATAGCTTCGTGCAAAATATGACGTTTT
TAGGTTGGCAGCTTAATGGACAAATGGCCATTACTGTTACATGTCTTTTGTTATTTATTGGTGCAATGGGAAAATCAGCA
CAATTTCTTTTACATACATGGCTCCCTGATGCCATGGAAGGGCCAACACCTGTATCAGCACTTATTCATGCCGCTACAAT
GGTAACGGCTGGTGTTTTTATGGTTGCGCGTATGTCGCCAATTTTTGAACTTTCTTCAATAGCTTTGACTGTAATTGTTA
TTATTGGAGCGACGACTGCATTTTTTGCAGCAACTGTGGGATTGGTGCAAAATGACATTAAGCGTGTTATTGCTTATTCT
ACATGTTCGCAACTTGGTTATATGTTTGTTGCATTAGGTGTTGGAGCTTATGGAGCGGCTGTTTTTCATCTCTTTACCCA
TGCTTTTTTTAAAGCTTTATTATTTCTTGGCGCAGGTTCTGTGATACATGCTGTATCTGATGAGCAAGATATGCGAAAAA
TGGGAGGGTTACGCAAGCGTATAAAGATAACTTATTGGATGATGATGATAGGAACTATCGCATTGACCGGTGTTGGAATT
CCTGGGACTGCTTTCGGCACAGCAGGTTTTTTCTCAAAAGATGCGATTATAGAGTCTGCTTTTGCATCGCATAATATTGC
TTCAGGATATGCTTTCTATCTTCTTGTTTTTTCGGCCTTTTTAACAAGCTTTTACTCATGGCGGCTTATATTTATGACAT
TTCACGGTAAACCACGAGCTACAGTTGATGTTATGCATCATGTTCATGAATCGCCTCCAGTGATGTTAATTCCACTATTT
ATTTTATCTATTGGAGCAATATTTGCTGGTGTTGTTTCCCACCCTTATTTCTTTGGTGACTTATATGATGCTTTTTGGAA
GGGAGCATTATTTACAAGCAGCTACAATCATATTCTTCATGATGCCCATCATGTATTTAACTGGGTAAAATGGTCGCCAT
TTATAGCGATGGTTCTTGGGTTTATGTTAGCCTATTTATTTTATATCTCTGTTCCTTCCATTCCCAAGAAAATTGCTAAA
TTAATGCCTGGATTGTATCGTTTTCTTTACCATAAATGGTATTTTGATGAATTGTATAACGTTCTATTTGTTCGCTCTGC
TTTAAGAATTGGTTCTTGTCTTTGGAAAGTGGGGGACGGTAAGATTATTGATGGTTTGGGTCCGAATGGTATCGCCGCAA
GTGTTATTAATATTACAAATAGAGTTATTCGGTTGCAGACAGGCTATCTTTATCATTATGCATTTGTAATGCTTATTGGC
ATTGCATCGCTGATCACATGGATGATGATCGGGGGCGTAAACTGA

Upstream 100 bases:

>100_bases
TGCTGAAGCTGCAATTGGTTTGGCAATTCTTGTTGTTTTCTTCCGTAATCGTGGTTCTATTGCGGTTGAAGATGTTAATG
TGATGAAAGGCTGACCAATG

Downstream 100 bases:

>100_bases
TGACTGATTGGCCTATTCTTTCTACGGTTACATTTTTGCCGCTTGTTGGTGTAATTTTGATTCTCTTTATCAAAGATGAT
AGCGAGGCAGCACGATATAA

Product: NADH dehydrogenase subunit L

Products: NA

Alternate protein names: NADH dehydrogenase I subunit L; NDH-1 subunit L [H]

Number of amino acids: Translated: 654; Mature: 654

Protein sequence:

>654_residues
MYYTIVFLPLLGFLIAAIAGKTIGDRASELVTCSFMVIVATLSWVAFFNIAFGHTPVVDVLVLHWLDVGSLSFSWALHID
TLTSVMLIVVNSVSALVHIYSIGYMHHDPSRPRFFSYLSLFTFMMLMLVTSNNLLQMFFGWEGVGLASYLLIGFWFQRDS
ANKAAMKAFVVNRVGDFGFLLGIFSIFVLFQSVDFTSIFAKAADNSFVQNMTFLGWQLNGQMAITVTCLLLFIGAMGKSA
QFLLHTWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPIFELSSIALTVIVIIGATTAFFAATVGLVQNDIKRVIAYS
TCSQLGYMFVALGVGAYGAAVFHLFTHAFFKALLFLGAGSVIHAVSDEQDMRKMGGLRKRIKITYWMMMIGTIALTGVGI
PGTAFGTAGFFSKDAIIESAFASHNIASGYAFYLLVFSAFLTSFYSWRLIFMTFHGKPRATVDVMHHVHESPPVMLIPLF
ILSIGAIFAGVVSHPYFFGDLYDAFWKGALFTSSYNHILHDAHHVFNWVKWSPFIAMVLGFMLAYLFYISVPSIPKKIAK
LMPGLYRFLYHKWYFDELYNVLFVRSALRIGSCLWKVGDGKIIDGLGPNGIAASVINITNRVIRLQTGYLYHYAFVMLIG
IASLITWMMIGGVN

Sequences:

>Translated_654_residues
MYYTIVFLPLLGFLIAAIAGKTIGDRASELVTCSFMVIVATLSWVAFFNIAFGHTPVVDVLVLHWLDVGSLSFSWALHID
TLTSVMLIVVNSVSALVHIYSIGYMHHDPSRPRFFSYLSLFTFMMLMLVTSNNLLQMFFGWEGVGLASYLLIGFWFQRDS
ANKAAMKAFVVNRVGDFGFLLGIFSIFVLFQSVDFTSIFAKAADNSFVQNMTFLGWQLNGQMAITVTCLLLFIGAMGKSA
QFLLHTWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPIFELSSIALTVIVIIGATTAFFAATVGLVQNDIKRVIAYS
TCSQLGYMFVALGVGAYGAAVFHLFTHAFFKALLFLGAGSVIHAVSDEQDMRKMGGLRKRIKITYWMMMIGTIALTGVGI
PGTAFGTAGFFSKDAIIESAFASHNIASGYAFYLLVFSAFLTSFYSWRLIFMTFHGKPRATVDVMHHVHESPPVMLIPLF
ILSIGAIFAGVVSHPYFFGDLYDAFWKGALFTSSYNHILHDAHHVFNWVKWSPFIAMVLGFMLAYLFYISVPSIPKKIAK
LMPGLYRFLYHKWYFDELYNVLFVRSALRIGSCLWKVGDGKIIDGLGPNGIAASVINITNRVIRLQTGYLYHYAFVMLIG
IASLITWMMIGGVN
>Mature_654_residues
MYYTIVFLPLLGFLIAAIAGKTIGDRASELVTCSFMVIVATLSWVAFFNIAFGHTPVVDVLVLHWLDVGSLSFSWALHID
TLTSVMLIVVNSVSALVHIYSIGYMHHDPSRPRFFSYLSLFTFMMLMLVTSNNLLQMFFGWEGVGLASYLLIGFWFQRDS
ANKAAMKAFVVNRVGDFGFLLGIFSIFVLFQSVDFTSIFAKAADNSFVQNMTFLGWQLNGQMAITVTCLLLFIGAMGKSA
QFLLHTWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPIFELSSIALTVIVIIGATTAFFAATVGLVQNDIKRVIAYS
TCSQLGYMFVALGVGAYGAAVFHLFTHAFFKALLFLGAGSVIHAVSDEQDMRKMGGLRKRIKITYWMMMIGTIALTGVGI
PGTAFGTAGFFSKDAIIESAFASHNIASGYAFYLLVFSAFLTSFYSWRLIFMTFHGKPRATVDVMHHVHESPPVMLIPLF
ILSIGAIFAGVVSHPYFFGDLYDAFWKGALFTSSYNHILHDAHHVFNWVKWSPFIAMVLGFMLAYLFYISVPSIPKKIAK
LMPGLYRFLYHKWYFDELYNVLFVRSALRIGSCLWKVGDGKIIDGLGPNGIAASVINITNRVIRLQTGYLYHYAFVMLIG
IASLITWMMIGGVN

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1009

COG function: function code CP; NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit

Gene ontology:

Cell location: Cellular chromatophore membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 5 family [H]

Homologues:

Organism=Homo sapiens, GI251831117, Length=427, Percent_Identity=41.4519906323185, Blast_Score=310, Evalue=2e-84,
Organism=Escherichia coli, GI1788614, Length=641, Percent_Identity=38.2215288611544, Blast_Score=347, Evalue=1e-96,
Organism=Escherichia coli, GI1788829, Length=436, Percent_Identity=30.5045871559633, Blast_Score=143, Evalue=4e-35,
Organism=Escherichia coli, GI1788831, Length=342, Percent_Identity=32.1637426900585, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI1788827, Length=435, Percent_Identity=26.8965517241379, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1788613, Length=358, Percent_Identity=27.0949720670391, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI2367154, Length=234, Percent_Identity=26.9230769230769, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI145693160, Length=231, Percent_Identity=26.4069264069264, Blast_Score=70, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001750
- InterPro:   IPR001516
- InterPro:   IPR003945
- InterPro:   IPR018393 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF00662 Oxidored_q1_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 72496; Mature: 72496

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYYTIVFLPLLGFLIAAIAGKTIGDRASELVTCSFMVIVATLSWVAFFNIAFGHTPVVDV
CEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LVLHWLDVGSLSFSWALHIDTLTSVMLIVVNSVSALVHIYSIGYMHHDPSRPRFFSYLSL
HHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCHHHHHHHH
FTFMMLMLVTSNNLLQMFFGWEGVGLASYLLIGFWFQRDSANKAAMKAFVVNRVGDFGFL
HHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHH
LGIFSIFVLFQSVDFTSIFAKAADNSFVQNMTFLGWQLNGQMAITVTCLLLFIGAMGKSA
HHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHEEEEECCCHHHHHHHHHHHHHCCCCCH
QFLLHTWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPIFELSSIALTVIVIIGATTA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
FFAATVGLVQNDIKRVIAYSTCSQLGYMFVALGVGAYGAAVFHLFTHAFFKALLFLGAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VIHAVSDEQDMRKMGGLRKRIKITYWMMMIGTIALTGVGIPGTAFGTAGFFSKDAIIESA
HEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
FASHNIASGYAFYLLVFSAFLTSFYSWRLIFMTFHGKPRATVDVMHHVHESPPVMLIPLF
HHCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHCCCCCEEHHHHH
ILSIGAIFAGVVSHPYFFGDLYDAFWKGALFTSSYNHILHDAHHVFNWVKWSPFIAMVLG
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FMLAYLFYISVPSIPKKIAKLMPGLYRFLYHKWYFDELYNVLFVRSALRIGSCLWKVGDG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KIIDGLGPNGIAASVINITNRVIRLQTGYLYHYAFVMLIGIASLITWMMIGGVN
CEECCCCCCHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MYYTIVFLPLLGFLIAAIAGKTIGDRASELVTCSFMVIVATLSWVAFFNIAFGHTPVVDV
CEEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHH
LVLHWLDVGSLSFSWALHIDTLTSVMLIVVNSVSALVHIYSIGYMHHDPSRPRFFSYLSL
HHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCEECCCCCCHHHHHHHH
FTFMMLMLVTSNNLLQMFFGWEGVGLASYLLIGFWFQRDSANKAAMKAFVVNRVGDFGFL
HHHHHHHHHHCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCHHHHH
LGIFSIFVLFQSVDFTSIFAKAADNSFVQNMTFLGWQLNGQMAITVTCLLLFIGAMGKSA
HHHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHEEEEECCCHHHHHHHHHHHHHCCCCCH
QFLLHTWLPDAMEGPTPVSALIHAATMVTAGVFMVARMSPIFELSSIALTVIVIIGATTA
HHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
FFAATVGLVQNDIKRVIAYSTCSQLGYMFVALGVGAYGAAVFHLFTHAFFKALLFLGAGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCH
VIHAVSDEQDMRKMGGLRKRIKITYWMMMIGTIALTGVGIPGTAFGTAGFFSKDAIIESA
HEEECCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
FASHNIASGYAFYLLVFSAFLTSFYSWRLIFMTFHGKPRATVDVMHHVHESPPVMLIPLF
HHCCCCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHCCCCCEEHHHHH
ILSIGAIFAGVVSHPYFFGDLYDAFWKGALFTSSYNHILHDAHHVFNWVKWSPFIAMVLG
HHHHHHHHHHHHHCCHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
FMLAYLFYISVPSIPKKIAKLMPGLYRFLYHKWYFDELYNVLFVRSALRIGSCLWKVGDG
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KIIDGLGPNGIAASVINITNRVIRLQTGYLYHYAFVMLIGIASLITWMMIGGVN
CEECCCCCCHHHHHHHHHHHHHEEEECCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8566820 [H]