| Definition | Bartonella henselae str. Houston-1, complete genome. |
|---|---|
| Accession | NC_005956 |
| Length | 1,931,047 |
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The map label for this gene is mrcA2 [H]
Identifier: 49475633
GI number: 49475633
Start: 975198
End: 977660
Strand: Reverse
Name: mrcA2 [H]
Synonym: BH08700
Alternate gene names: 49475633
Gene position: 977660-975198 (Counterclockwise)
Preceding gene: 49475634
Following gene: 49475632
Centisome position: 50.63
GC content: 40.48
Gene sequence:
>2463_bases ATGATTTTTTTTAGATATCTTCTGAGTTTTGTTGTTATAATTGGGTTTTGGAGAGTAATGACGCAGGGAGCGATAGCAAA AAGTCAGACGAGTCCGCTTCCTGACTATGAAGTTCTTTCGCTCTATGAGCCACCTGTGATGACTCGCGTTCATGCTTCTG ATGGAAGCCTTATGGCAGAATTTGCCACAAAACGTCGCCTCTATTTACCAATTCAGTCAATCCCAAAACTTCTTAAAGAC GCTTTTATTTCAGCTGAAGACAAAAATTTTTATCATCATTTTGGTTTAGATCCCGAAGGGCTCGCTAGAGCTTTAATCAA TAATATCCGCAATATTGGTTCTGGAAAACGTCCGGAGGGGGCATCAACCATTACACAACAAGTCGCTAAAAACTTTCTTT TAAGCTCAGACGCAACGTTGGAGCGTAAATTAAAGGAAGCTATCCTGGCAATGCGTATTGAGAAGACTTACTCGAAAGAT CATATTCTCGAACTTTATCTCAATGAAATTTATCTTGGTCGTAGTACTTATGGTATCGCAGCAGCATCTTTGACCTATTT CAATAAATCCGTAAATGATCTTACCTTAGAGCAGTGCGCTTATTTGGCTGCTCTTCCCAAAGGTCCAGCAAATTATGATC CATTTAAGAATACACAACGGGCTATTAATCGGCGCAATTGGGTTATAGATAGGATGGTTGCAAATGGATATGTAACACAT GAACAAGGTGAAGAAGCTAAAGCAAAACCGTTAGGGGTCACAATACGGGGAAGCGATAATTACGTTTTTGCTGCTGACTA TTTTACTGAAGAAGTGCGACGTCGTCTAATGCACCGCTATGGAGCAAAAACACTTTACGAAGGTGGACTTTCAATTCGTA CAACACTTGATCCGCATTTGCAACTTATTGCTAGGCGTGCTTTGCACAATGGATTAATTAAATTTGATCATTCACAAGGA TGGCGCGGAGCTTATGGACATATTGATAAGAAAGATGATTGGGGTGTAGAACTTGCAAATATAGCTGGATTAAGTGACGT TCCTGAATGGCGTTTAGCTGTTGTTCTTTCTGCTAACGCTCATAAAGTAGAGATTGGTTTACAGCCACAGCGCGAAGCTT CAGGTTTATTATCAACAAAGCGGGAAATTGCTGTTTTGTCTGAAACCGATTCAAAATGGGCATTACATATTATTAAAGAA AATGGCTATCGAAAAACTGTTCGGGATTTATCTCATGTTCTGCAAGTTGGAGATGTTGTTTTTGTCGAAAAAACCTCAAA TACAGACAATATTTATCGTTTACAACAAATCCCAAAGGTTGAGGGTGCAATTGTTGCTATGGAACCTCATACAGGGCGTG TTCTTGCGATGGTAGGAGGGTTTTCTTTTGCAGCATCTGAATTTAATCGTGCAACACAAGCCTATCGTCAGCCTGGTTCT GCTTTCAAGCCTTTTGTATATGCAGCCGCACTTGATAATGGATATACACCAGCATCCGTTGTTTTAGATGGTCCTATTGA AATTCGCCAATATAATGGTGAGGTTTGGCAACCTAAAAACTATGGTGGCACTTTTGCAGGACCTTCGACGTTGCGTTATG GCATTGAATATTCTCGTAATCTTATGACGATACGGCTTGCCAATGATATGGGAATGCCTCTTGTTGCTGAATATGCAGAG CGTTTTGGTATTGTAGATGAATTACAACCTTATCTTCCCATGGCTTTAGGGGCTGCTGAAACAACAGTTCTACGGATGGT TACAGCTTATTCAGTGATAGCCAATGGGGGACGCTCTATTAATCCTTCTTTAATAGACAGAATTCAAGATCGTTATGGGA AAACAATTTACCGTCATGATGATCGTTTTTGTGAAAATTGTAATGCTCAGTCATGGGATAATCAAAGTGAACCCACATTG ATTGATGAGCGAGATCAAGTTCTTGATCCTATGACAGCTTATCAGATTACATCAATGATGGAAGGGGTTATTCAGCGCGG TACAGCTGGGCATTTGCGTTATCTCAATCGACATATTGCTGCTAAAACAGGAACAACGAATGACTCCAAAGATGTATGGT TTATGGGATTTACCCCTGATCTTGTTGTTGGTATTTTTGTCGGTTACGATCAACCAGCACCTTTAGGATACAATGGAACG GGAAGTTCATTGGCCGCGCCTATTTTTGGTGAGTTTATGGCAGCGGCTTTGAAAGGAAAGCCAGATGTACCATTTAAAAT GCCGGAAGGTATGATTTTAATGCCTATTAATCGTAAGACGGGTATGCTTGCAGAAAGAGGAGAGCAAGATGTTATTATAG AAGCCTTTAAACCAGGAACTGGACCTGCTGATATATATCAGGTCATTGGAAGTACGAACTCTTTTCAAGAAGGTGTTCCT GTAATAACGACTTCTCCACAAGTCAACAAGGCTCTTGAAAGTGGTACAGGTGGGTTGTATTAA
Upstream 100 bases:
>100_bases AAACAGTTTTTTCTCGCAGTAGTATTTCATGTCGCCTTTTTGTTGGTGAGGTGATGTGTTTTTTTTTCTCATTCTAAAGA AAGCGATAGCCGTTTTGATG
Downstream 100 bases:
>100_bases TCGGTAAGAATCTTTTTTAGGTAACTGGCAGAGAGAAAGAATTTTTCTCTGTTTTTTGCAGTATAGCTACAGTCAAAGAG CTTAAGGAAGCTATGCTGGC
Product: penicillin-binding protein 1a
Products: NA
Alternate protein names: PBP-1a; PBP1a; Penicillin-insensitive transglycosylase; Peptidoglycan TGase; Penicillin-sensitive transpeptidase; DD-transpeptidase [H]
Number of amino acids: Translated: 820; Mature: 820
Protein sequence:
>820_residues MIFFRYLLSFVVIIGFWRVMTQGAIAKSQTSPLPDYEVLSLYEPPVMTRVHASDGSLMAEFATKRRLYLPIQSIPKLLKD AFISAEDKNFYHHFGLDPEGLARALINNIRNIGSGKRPEGASTITQQVAKNFLLSSDATLERKLKEAILAMRIEKTYSKD HILELYLNEIYLGRSTYGIAAASLTYFNKSVNDLTLEQCAYLAALPKGPANYDPFKNTQRAINRRNWVIDRMVANGYVTH EQGEEAKAKPLGVTIRGSDNYVFAADYFTEEVRRRLMHRYGAKTLYEGGLSIRTTLDPHLQLIARRALHNGLIKFDHSQG WRGAYGHIDKKDDWGVELANIAGLSDVPEWRLAVVLSANAHKVEIGLQPQREASGLLSTKREIAVLSETDSKWALHIIKE NGYRKTVRDLSHVLQVGDVVFVEKTSNTDNIYRLQQIPKVEGAIVAMEPHTGRVLAMVGGFSFAASEFNRATQAYRQPGS AFKPFVYAAALDNGYTPASVVLDGPIEIRQYNGEVWQPKNYGGTFAGPSTLRYGIEYSRNLMTIRLANDMGMPLVAEYAE RFGIVDELQPYLPMALGAAETTVLRMVTAYSVIANGGRSINPSLIDRIQDRYGKTIYRHDDRFCENCNAQSWDNQSEPTL IDERDQVLDPMTAYQITSMMEGVIQRGTAGHLRYLNRHIAAKTGTTNDSKDVWFMGFTPDLVVGIFVGYDQPAPLGYNGT GSSLAAPIFGEFMAAALKGKPDVPFKMPEGMILMPINRKTGMLAERGEQDVIIEAFKPGTGPADIYQVIGSTNSFQEGVP VITTSPQVNKALESGTGGLY
Sequences:
>Translated_820_residues MIFFRYLLSFVVIIGFWRVMTQGAIAKSQTSPLPDYEVLSLYEPPVMTRVHASDGSLMAEFATKRRLYLPIQSIPKLLKD AFISAEDKNFYHHFGLDPEGLARALINNIRNIGSGKRPEGASTITQQVAKNFLLSSDATLERKLKEAILAMRIEKTYSKD HILELYLNEIYLGRSTYGIAAASLTYFNKSVNDLTLEQCAYLAALPKGPANYDPFKNTQRAINRRNWVIDRMVANGYVTH EQGEEAKAKPLGVTIRGSDNYVFAADYFTEEVRRRLMHRYGAKTLYEGGLSIRTTLDPHLQLIARRALHNGLIKFDHSQG WRGAYGHIDKKDDWGVELANIAGLSDVPEWRLAVVLSANAHKVEIGLQPQREASGLLSTKREIAVLSETDSKWALHIIKE NGYRKTVRDLSHVLQVGDVVFVEKTSNTDNIYRLQQIPKVEGAIVAMEPHTGRVLAMVGGFSFAASEFNRATQAYRQPGS AFKPFVYAAALDNGYTPASVVLDGPIEIRQYNGEVWQPKNYGGTFAGPSTLRYGIEYSRNLMTIRLANDMGMPLVAEYAE RFGIVDELQPYLPMALGAAETTVLRMVTAYSVIANGGRSINPSLIDRIQDRYGKTIYRHDDRFCENCNAQSWDNQSEPTL IDERDQVLDPMTAYQITSMMEGVIQRGTAGHLRYLNRHIAAKTGTTNDSKDVWFMGFTPDLVVGIFVGYDQPAPLGYNGT GSSLAAPIFGEFMAAALKGKPDVPFKMPEGMILMPINRKTGMLAERGEQDVIIEAFKPGTGPADIYQVIGSTNSFQEGVP VITTSPQVNKALESGTGGLY >Mature_820_residues MIFFRYLLSFVVIIGFWRVMTQGAIAKSQTSPLPDYEVLSLYEPPVMTRVHASDGSLMAEFATKRRLYLPIQSIPKLLKD AFISAEDKNFYHHFGLDPEGLARALINNIRNIGSGKRPEGASTITQQVAKNFLLSSDATLERKLKEAILAMRIEKTYSKD HILELYLNEIYLGRSTYGIAAASLTYFNKSVNDLTLEQCAYLAALPKGPANYDPFKNTQRAINRRNWVIDRMVANGYVTH EQGEEAKAKPLGVTIRGSDNYVFAADYFTEEVRRRLMHRYGAKTLYEGGLSIRTTLDPHLQLIARRALHNGLIKFDHSQG WRGAYGHIDKKDDWGVELANIAGLSDVPEWRLAVVLSANAHKVEIGLQPQREASGLLSTKREIAVLSETDSKWALHIIKE NGYRKTVRDLSHVLQVGDVVFVEKTSNTDNIYRLQQIPKVEGAIVAMEPHTGRVLAMVGGFSFAASEFNRATQAYRQPGS AFKPFVYAAALDNGYTPASVVLDGPIEIRQYNGEVWQPKNYGGTFAGPSTLRYGIEYSRNLMTIRLANDMGMPLVAEYAE RFGIVDELQPYLPMALGAAETTVLRMVTAYSVIANGGRSINPSLIDRIQDRYGKTIYRHDDRFCENCNAQSWDNQSEPTL IDERDQVLDPMTAYQITSMMEGVIQRGTAGHLRYLNRHIAAKTGTTNDSKDVWFMGFTPDLVVGIFVGYDQPAPLGYNGT GSSLAAPIFGEFMAAALKGKPDVPFKMPEGMILMPINRKTGMLAERGEQDVIIEAFKPGTGPADIYQVIGSTNSFQEGVP VITTSPQVNKALESGTGGLY
Specific function: Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal
COG id: COG5009
COG function: function code M; Membrane carboxypeptidase/penicillin-binding protein
Gene ontology:
Cell location: Cell inner membrane; Single-pass type II membrane protein [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: In the C-terminal section; belongs to the transpeptidase family [H]
Homologues:
Organism=Escherichia coli, GI87082258, Length=848, Percent_Identity=33.7264150943396, Blast_Score=429, Evalue=1e-121, Organism=Escherichia coli, GI1786343, Length=274, Percent_Identity=35.4014598540146, Blast_Score=157, Evalue=2e-39, Organism=Escherichia coli, GI1788867, Length=317, Percent_Identity=29.3375394321767, Blast_Score=110, Evalue=5e-25, Organism=Escherichia coli, GI1789601, Length=233, Percent_Identity=31.7596566523605, Blast_Score=102, Evalue=1e-22,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR012338 - InterPro: IPR001264 - InterPro: IPR011816 - InterPro: IPR001460 [H]
Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]
EC number: 2.4.2.-; 3.4.-.-
Molecular weight: Translated: 91142; Mature: 91142
Theoretical pI: Translated: 7.79; Mature: 7.79
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.2 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIFFRYLLSFVVIIGFWRVMTQGAIAKSQTSPLPDYEVLSLYEPPVMTRVHASDGSLMAE CHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHEECCCCCEEEEECCCCCHHHH FATKRRLYLPIQSIPKLLKDAFISAEDKNFYHHFGLDPEGLARALINNIRNIGSGKRPEG HHHCCEEEECHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCC ASTITQQVAKNFLLSSDATLERKLKEAILAMRIEKTYSKDHILELYLNEIYLGRSTYGIA HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCHH AASLTYFNKSVNDLTLEQCAYLAALPKGPANYDPFKNTQRAINRRNWVIDRMVANGYVTH HHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEC EQGEEAKAKPLGVTIRGSDNYVFAADYFTEEVRRRLMHRYGAKTLYEGGLSIRTTLDPHL CCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEECCHHH QLIARRALHNGLIKFDHSQGWRGAYGHIDKKDDWGVELANIAGLSDVPEWRLAVVLSANA HHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEHHHCCCCCCCCEEEEEEEECCC HKVEIGLQPQREASGLLSTKREIAVLSETDSKWALHIIKENGYRKTVRDLSHVLQVGDVV EEEEECCCCCHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHCCEE FVEKTSNTDNIYRLQQIPKVEGAIVAMEPHTGRVLAMVGGFSFAASEFNRATQAYRQPGS EEEECCCCCCEEHHHHCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCC AFKPFVYAAALDNGYTPASVVLDGPIEIRQYNGEVWQPKNYGGTFAGPSTLRYGIEYSRN CCCCEEEEEECCCCCCCCEEEECCCEEEEECCCCEECCCCCCCCCCCHHHHHCCHHHCCC LMTIRLANDMGMPLVAEYAERFGIVDELQPYLPMALGAAETTVLRMVTAYSVIANGGRSI EEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC NPSLIDRIQDRYGKTIYRHDDRFCENCNAQSWDNQSEPTLIDERDQVLDPMTAYQITSMM CHHHHHHHHHHHCCEEEECCHHHHHCCCCCCCCCCCCCCEECCHHHHHCCHHHHHHHHHH EGVIQRGTAGHLRYLNRHIAAKTGTTNDSKDVWFMGFTPDLVVGIFVGYDQPAPLGYNGT HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHEEEEECCCCCCCCCCCCC GSSLAAPIFGEFMAAALKGKPDVPFKMPEGMILMPINRKTGMLAERGEQDVIIEAFKPGT CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHCCCCCEEEEEECCCC GPADIYQVIGSTNSFQEGVPVITTSPQVNKALESGTGGLY CHHHHHHHHCCCCCHHCCCCEEECCCHHHHHHHCCCCCCC >Mature Secondary Structure MIFFRYLLSFVVIIGFWRVMTQGAIAKSQTSPLPDYEVLSLYEPPVMTRVHASDGSLMAE CHHHHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCHHHEECCCCCEEEEECCCCCHHHH FATKRRLYLPIQSIPKLLKDAFISAEDKNFYHHFGLDPEGLARALINNIRNIGSGKRPEG HHHCCEEEECHHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHCCCCCCCCC ASTITQQVAKNFLLSSDATLERKLKEAILAMRIEKTYSKDHILELYLNEIYLGRSTYGIA HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCCCHH AASLTYFNKSVNDLTLEQCAYLAALPKGPANYDPFKNTQRAINRRNWVIDRMVANGYVTH HHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCEEEC EQGEEAKAKPLGVTIRGSDNYVFAADYFTEEVRRRLMHRYGAKTLYEGGLSIRTTLDPHL CCCCCCCCCCEEEEEECCCCEEEEHHHHHHHHHHHHHHHHCCCHHHHCCCEEEEECCHHH QLIARRALHNGLIKFDHSQGWRGAYGHIDKKDDWGVELANIAGLSDVPEWRLAVVLSANA HHHHHHHHHCCCEEEECCCCCCCCCCCCCCCCCCCEEEHHHCCCCCCCCEEEEEEEECCC HKVEIGLQPQREASGLLSTKREIAVLSETDSKWALHIIKENGYRKTVRDLSHVLQVGDVV EEEEECCCCCHHHHHHHHCCCCEEEEECCCCCEEEEEEECCCCHHHHHHHHHHHHHCCEE FVEKTSNTDNIYRLQQIPKVEGAIVAMEPHTGRVLAMVGGFSFAASEFNRATQAYRQPGS EEEECCCCCCEEHHHHCCCCCCEEEEECCCCCEEEEEECCCHHHHHHHHHHHHHHHCCCC AFKPFVYAAALDNGYTPASVVLDGPIEIRQYNGEVWQPKNYGGTFAGPSTLRYGIEYSRN CCCCEEEEEECCCCCCCCEEEECCCEEEEECCCCEECCCCCCCCCCCHHHHHCCHHHCCC LMTIRLANDMGMPLVAEYAERFGIVDELQPYLPMALGAAETTVLRMVTAYSVIANGGRSI EEEEEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCC NPSLIDRIQDRYGKTIYRHDDRFCENCNAQSWDNQSEPTLIDERDQVLDPMTAYQITSMM CHHHHHHHHHHHCCEEEECCHHHHHCCCCCCCCCCCCCCEECCHHHHHCCHHHHHHHHHH EGVIQRGTAGHLRYLNRHIAAKTGTTNDSKDVWFMGFTPDLVVGIFVGYDQPAPLGYNGT HHHHHCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHEEEEECCCCCCCCCCCCC GSSLAAPIFGEFMAAALKGKPDVPFKMPEGMILMPINRKTGMLAERGEQDVIIEAFKPGT CCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCCCCCHHHCCCCCEEEEEECCCC GPADIYQVIGSTNSFQEGVPVITTSPQVNKALESGTGGLY CHHHHHHHHCCCCCHHCCCCEEECCCHHHHHHHCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]
Inhibitor: NA
Structure determination priority: 6.0
TargetDB status: NA
Availability: NA
References: NA