Click here to switch to the map view.

The map label for this gene is pcsA [H]

Identifier: 49475617

GI number: 49475617

Start: 959018

End: 959728

Strand: Reverse

Name: pcsA [H]

Synonym: BH08530

Alternate gene names: 49475617

Gene position: 959728-959018 (Counterclockwise)

Preceding gene: 49475621

Following gene: 49475616

Centisome position: 49.7

GC content: 35.72

Gene sequence:

>711_bases
ATGCCACAAGCAAAGGCTTTTTCTGTTCATTTATTAACAGCTTCGGGTTCGTTTTTAGCATTTCTTTCTCTTATATCGGC
CTCTCAAAAAGAATGGACTGCTATGTTTTGTTGGCTCGGACTTGCACTTCTCGTTGACGGTATCGATGGGCCAATTGCGC
GCAAACTTGATGTTAAATATGTACTTCCAACATGGTCTGGAGAACTCCTGGATAATATCATTGATTATGTGACTTATGTC
TTAATTCCAGCTTTTGCGCTTTATCAAAGTGGTTTTATGGGATCAGGATTATCATTTTTATTAAGTGCGATTATTGTCAT
TTCATCAGCGATTTATTACGCAGATACTGGAATGAAAACCAAAGAAAACTTTTTTAAAGGATTTCCTGTCGTTTGGAATA
TGATGGGTTTTACGCTTTTTGTCGTAAGACCAGGGGAGTGGATCACTTTTACCATTATTGTCTTATCAGCAATCATATCT
TTTTTACCCATTTATTTCATCCATCCAGTAAGGGTCATCCGTTTGCGTAAGCTTAATTTTCCAATTTTTCTTTTATGGTG
TTCCTTTGGTGTTGCTGCATTTTTTTACCAACTGAATGCCCCATTTTGGGTTAAGATGGGAATTTCAGTAACAGGTATTT
ATATGTATTCTATTGGTGCTATCATGCAAATATTTCCTCAATTAGGAATAAAAAAACAATTAGATAGATAG

Upstream 100 bases:

>100_bases
GAATGAAGATTTTAGAAACGAGGATAAGAAAACCTTGAAACGGAAGCTAACAAAAAAAATCAAAACGAATGCAGATCTTT
TGCGCCATAAAAAAGTAACA

Downstream 100 bases:

>100_bases
TTTTAGGAAGAGTATGAGATGCGAATTGACTTTGGGGCAGGTGATGAGATTTCTTTTATAAAAAAAGGGCATGCTGGTGT
TATAAAGCTCGCACGCTCTT

Product: phosphatidylcholine synthase

Products: NA

Alternate protein names: PC synthase; CDP-diglyceride-choline O-phosphatidyltransferase [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MPQAKAFSVHLLTASGSFLAFLSLISASQKEWTAMFCWLGLALLVDGIDGPIARKLDVKYVLPTWSGELLDNIIDYVTYV
LIPAFALYQSGFMGSGLSFLLSAIIVISSAIYYADTGMKTKENFFKGFPVVWNMMGFTLFVVRPGEWITFTIIVLSAIIS
FLPIYFIHPVRVIRLRKLNFPIFLLWCSFGVAAFFYQLNAPFWVKMGISVTGIYMYSIGAIMQIFPQLGIKKQLDR

Sequences:

>Translated_236_residues
MPQAKAFSVHLLTASGSFLAFLSLISASQKEWTAMFCWLGLALLVDGIDGPIARKLDVKYVLPTWSGELLDNIIDYVTYV
LIPAFALYQSGFMGSGLSFLLSAIIVISSAIYYADTGMKTKENFFKGFPVVWNMMGFTLFVVRPGEWITFTIIVLSAIIS
FLPIYFIHPVRVIRLRKLNFPIFLLWCSFGVAAFFYQLNAPFWVKMGISVTGIYMYSIGAIMQIFPQLGIKKQLDR
>Mature_235_residues
PQAKAFSVHLLTASGSFLAFLSLISASQKEWTAMFCWLGLALLVDGIDGPIARKLDVKYVLPTWSGELLDNIIDYVTYVL
IPAFALYQSGFMGSGLSFLLSAIIVISSAIYYADTGMKTKENFFKGFPVVWNMMGFTLFVVRPGEWITFTIIVLSAIISF
LPIYFIHPVRVIRLRKLNFPIFLLWCSFGVAAFFYQLNAPFWVKMGISVTGIYMYSIGAIMQIFPQLGIKKQLDR

Specific function: Condenses choline with CDP-diglyceride to produce phosphatidylcholine and CMP [H]

COG id: COG1183

COG function: function code I; Phosphatidylserine synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.24 [H]

Molecular weight: Translated: 26568; Mature: 26437

Theoretical pI: Translated: 9.63; Mature: 9.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQAKAFSVHLLTASGSFLAFLSLISASQKEWTAMFCWLGLALLVDGIDGPIARKLDVKY
CCCCCEEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEE
VLPTWSGELLDNIIDYVTYVLIPAFALYQSGFMGSGLSFLLSAIIVISSAIYYADTGMKT
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEECCCCCH
KENFFKGFPVVWNMMGFTLFVVRPGEWITFTIIVLSAIISFLPIYFIHPVRVIRLRKLNF
HHHHHCCCHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PIFLLWCSFGVAAFFYQLNAPFWVKMGISVTGIYMYSIGAIMQIFPQLGIKKQLDR
CHHHHHHHHHHHHHHHHCCCCEEEEECCEEEHHHHHHHHHHHHHHHHCCCHHHCCC
>Mature Secondary Structure 
PQAKAFSVHLLTASGSFLAFLSLISASQKEWTAMFCWLGLALLVDGIDGPIARKLDVKY
CCCCEEEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCHHEEEEEE
VLPTWSGELLDNIIDYVTYVLIPAFALYQSGFMGSGLSFLLSAIIVISSAIYYADTGMKT
ECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHEECCCCCH
KENFFKGFPVVWNMMGFTLFVVRPGEWITFTIIVLSAIISFLPIYFIHPVRVIRLRKLNF
HHHHHCCCHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PIFLLWCSFGVAAFFYQLNAPFWVKMGISVTGIYMYSIGAIMQIFPQLGIKKQLDR
CHHHHHHHHHHHHHHHHCCCCEEEEECCEEEHHHHHHHHHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11214968 [H]