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The map label for this gene is hemS [H]

Identifier: 49475291

GI number: 49475291

Start: 579273

End: 580316

Strand: Reverse

Name: hemS [H]

Synonym: BH04960

Alternate gene names: 49475291

Gene position: 580316-579273 (Counterclockwise)

Preceding gene: 49475292

Following gene: 49475290

Centisome position: 30.05

GC content: 36.3

Gene sequence:

>1044_bases
ATGTCATATACAGCCGAAATGATTATTCGTTTGCGTGAAGAAAAAAAAGAGATGCGTAATCGTGATTTTGCAATCTCTAT
TGGTATATCTGAAGCAGAACTTATTGCTGCCTATTGTACAATTGGAAAAGCAAAAAGACTAAAAACTGATATTGCCGTTC
TCCTGGAAAATGCTCCTCAACTTGGAACAGTTATGGCATTGACACGTAATGAACATGCTGTTCATGAAATCACAGGATGT
TTTGAAAAAATTGTTCAAAACCAACATGTCCTTCTCACACTTGGTGAAATTGACCTACGTATTTTTGCAAAACAATGGAA
ATTTTGTTTTGAATACGAAGCAATTGTTCTTGGAAAGCCTACGAAAAGTCTGCATTTCTTTGATCAAAATGGCGTTGCTA
TTTTTAAACTCTATTCTAAAGATACCACAAATATGGCAGAGTGGAATAAACTTGTTGATAAGTTGCTCCATGAGGATCAA
TCACCCGTTCTTGATATCCCTCCAAAAGCAATTCCAAACAAGCGCGATATTGTAGAACTGAATGTTGAAGAATTTCGCGA
TCGTTGGCGGAAAATGACTGATGTACACCAACTTCACGGGATTATTTCTGAACTCAAAATTAATCGACATGATGCTGTAA
AATATGTAGGAAATGAATTTGCTCATGAATTAAAGAGAGAAGCTATTGAAATTATGCTCAACCAGGTTGCGCAACAAGAA
GTACCTATTATGTGCTTTGTTGGAAACAAGGGATGTATCCAAATTTTTAGTGGACAAATAAAAAACATTAAGCAAATGGG
ACCTTGGCTTAATGTTCTCGATAAAAAATTTCACCTGCATTTACTCATTCCTGGAATCAAAAATGTATGGTGCGTTCGCA
AACCTACCAGTGATGGTCATGTCACTTCACTTGAAGTTTTTGATGAAAATGATGAGATGATTATTCAATTCTTTGGTATG
CGAAAAGAAGGGCAAAAAGAACGTGAAGATTGGCGCTCTTTATTAAATAGTTTGCCTCAAAGCCACGCAGTAGCAGTCGC
TTAG

Upstream 100 bases:

>100_bases
TTGGGTAAAATGGTTTGAACCCTTAAAAAGGTTCAAACTATTGCTTTGAAATTGTAAAATTTTAAAAGTTAGATCTCAAA
AAATATTATAAGGAAAGTCC

Downstream 100 bases:

>100_bases
AAAGGTAAAGTTGGATATGTTTACACTTCTTTTACACAAACGACCAAAATTTTTCCTTATTTGTATACTGCTCTTTTTTA
CCTTCTTTTCTAAACAAGTG

Product: hemin degrading protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MSYTAEMIIRLREEKKEMRNRDFAISIGISEAELIAAYCTIGKAKRLKTDIAVLLENAPQLGTVMALTRNEHAVHEITGC
FEKIVQNQHVLLTLGEIDLRIFAKQWKFCFEYEAIVLGKPTKSLHFFDQNGVAIFKLYSKDTTNMAEWNKLVDKLLHEDQ
SPVLDIPPKAIPNKRDIVELNVEEFRDRWRKMTDVHQLHGIISELKINRHDAVKYVGNEFAHELKREAIEIMLNQVAQQE
VPIMCFVGNKGCIQIFSGQIKNIKQMGPWLNVLDKKFHLHLLIPGIKNVWCVRKPTSDGHVTSLEVFDENDEMIIQFFGM
RKEGQKEREDWRSLLNSLPQSHAVAVA

Sequences:

>Translated_347_residues
MSYTAEMIIRLREEKKEMRNRDFAISIGISEAELIAAYCTIGKAKRLKTDIAVLLENAPQLGTVMALTRNEHAVHEITGC
FEKIVQNQHVLLTLGEIDLRIFAKQWKFCFEYEAIVLGKPTKSLHFFDQNGVAIFKLYSKDTTNMAEWNKLVDKLLHEDQ
SPVLDIPPKAIPNKRDIVELNVEEFRDRWRKMTDVHQLHGIISELKINRHDAVKYVGNEFAHELKREAIEIMLNQVAQQE
VPIMCFVGNKGCIQIFSGQIKNIKQMGPWLNVLDKKFHLHLLIPGIKNVWCVRKPTSDGHVTSLEVFDENDEMIIQFFGM
RKEGQKEREDWRSLLNSLPQSHAVAVA
>Mature_346_residues
SYTAEMIIRLREEKKEMRNRDFAISIGISEAELIAAYCTIGKAKRLKTDIAVLLENAPQLGTVMALTRNEHAVHEITGCF
EKIVQNQHVLLTLGEIDLRIFAKQWKFCFEYEAIVLGKPTKSLHFFDQNGVAIFKLYSKDTTNMAEWNKLVDKLLHEDQS
PVLDIPPKAIPNKRDIVELNVEEFRDRWRKMTDVHQLHGIISELKINRHDAVKYVGNEFAHELKREAIEIMLNQVAQQEV
PIMCFVGNKGCIQIFSGQIKNIKQMGPWLNVLDKKFHLHLLIPGIKNVWCVRKPTSDGHVTSLEVFDENDEMIIQFFGMR
KEGQKEREDWRSLLNSLPQSHAVAVA

Specific function: Part of the binding-protein-dependent transport system for hemin [H]

COG id: COG3720

COG function: function code P; Putative heme degradation protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: To Y.enterocolitica hemS [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007845 [H]

Pfam domain/function: PF05171 HemS [H]

EC number: NA

Molecular weight: Translated: 40014; Mature: 39883

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYTAEMIIRLREEKKEMRNRDFAISIGISEAELIAAYCTIGKAKRLKTDIAVLLENAPQ
CCHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
LGTVMALTRNEHAVHEITGCFEKIVQNQHVLLTLGEIDLRIFAKQWKFCFEYEAIVLGKP
CCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHEEEEEEEEECC
TKSLHFFDQNGVAIFKLYSKDTTNMAEWNKLVDKLLHEDQSPVLDIPPKAIPNKRDIVEL
CCCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCEEEE
NVEEFRDRWRKMTDVHQLHGIISELKINRHDAVKYVGNEFAHELKREAIEIMLNQVAQQE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPIMCFVGNKGCIQIFSGQIKNIKQMGPWLNVLDKKFHLHLLIPGIKNVWCVRKPTSDGH
CCEEEEECCCCEEEEHHHHHHHHHHHCHHHHHHCCCEEEEEEECCCCCEEEEECCCCCCC
VTSLEVFDENDEMIIQFFGMRKEGQKEREDWRSLLNSLPQSHAVAVA
EEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEECC
>Mature Secondary Structure 
SYTAEMIIRLREEKKEMRNRDFAISIGISEAELIAAYCTIGKAKRLKTDIAVLLENAPQ
CHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCC
LGTVMALTRNEHAVHEITGCFEKIVQNQHVLLTLGEIDLRIFAKQWKFCFEYEAIVLGKP
CCEEEEEECCCHHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHEEEEEEEEECC
TKSLHFFDQNGVAIFKLYSKDTTNMAEWNKLVDKLLHEDQSPVLDIPPKAIPNKRDIVEL
CCCEEEECCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCEEEE
NVEEFRDRWRKMTDVHQLHGIISELKINRHDAVKYVGNEFAHELKREAIEIMLNQVAQQE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
VPIMCFVGNKGCIQIFSGQIKNIKQMGPWLNVLDKKFHLHLLIPGIKNVWCVRKPTSDGH
CCEEEEECCCCEEEEHHHHHHHHHHHCHHHHHHCCCEEEEEEECCCCCEEEEECCCCCCC
VTSLEVFDENDEMIIQFFGMRKEGQKEREDWRSLLNSLPQSHAVAVA
EEEEEEECCCCCEEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9026634; 11586360; 12142430 [H]