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The map label for this gene is ccmB [H]

Identifier: 49474932

GI number: 49474932

Start: 153299

End: 153964

Strand: Reverse

Name: ccmB [H]

Synonym: BH01140

Alternate gene names: 49474932

Gene position: 153964-153299 (Counterclockwise)

Preceding gene: 49474933

Following gene: 49474931

Centisome position: 7.97

GC content: 37.39

Gene sequence:

>666_bases
ATGAAAGCACTGTTCTGGCGTGATCTTAAATTAACCTTAGCACCACAAGCTTCCTCGTTAAAAGGGCTTTTGTTTTTCAT
TGCTATTATTATGATAATCCCCTTCGCCATTGGGCCAAATCCTAAAGTTCTTTCACAAATAGGTCCAGGTATATTATGGC
TGGGAGCTCTTCTCGCAGGACTTCTTAATCTCAATAAGCTTTTTCAAACCGATCATGATGATGGAAATCTTGACCAATTC
ATCCTTTCTGGACAAAGACAAAGTTTTACACTGATCGTATTAACCAAATGCCTTGCCCATTGGGTAGGAACTATGCTTCC
TCTTATTTTTGCCACTCCTTTTTTAGCATTCATGCTCCATTTAGATGCAATAATAACTTTTACAACAATACTCACTCTCT
TATGTGGAACACCAGCTATTATTTTTATTGGCGCTATCGGAGCTGCTCTTGCAACATCATTGTTGCATAGTACTCTTCTC
ATTTTTATCATAATCTTACCGTGGATTATTCCAATCATGATTTTTGGCGTTTCCGCTGCTACAGCTCCAACAAACCCAAA
TGTCTCTTTTCTCACTTCTTTGACTCTTCTTATCGGTTTTTCACTTCTTTTGAGTCTTTTTAGCTCCTTTATTGCAGCTA
TAACACTCAAACTTTTATCAGAATAA

Upstream 100 bases:

>100_bases
AAGGTGGTATGATTATCGCTGCAACCCATAGTCCTCTCGGCATTCCAGAAAACCATAAAATTACCTTGGAAAAATTTTTA
CCTCCCCAGGAGAAAATACA

Downstream 100 bases:

>100_bases
TAAAAGATGATTGCTGCACAACAAAACTCTGCCTATTATAAATTTCATGAATGAAACATTTCACACACATAAAATGAACA
CGCTTCCTGCAAGTTTTACC

Product: Heme exporter protein B

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycW [H]

Number of amino acids: Translated: 221; Mature: 221

Protein sequence:

>221_residues
MKALFWRDLKLTLAPQASSLKGLLFFIAIIMIIPFAIGPNPKVLSQIGPGILWLGALLAGLLNLNKLFQTDHDDGNLDQF
ILSGQRQSFTLIVLTKCLAHWVGTMLPLIFATPFLAFMLHLDAIITFTTILTLLCGTPAIIFIGAIGAALATSLLHSTLL
IFIIILPWIIPIMIFGVSAATAPTNPNVSFLTSLTLLIGFSLLLSLFSSFIAAITLKLLSE

Sequences:

>Translated_221_residues
MKALFWRDLKLTLAPQASSLKGLLFFIAIIMIIPFAIGPNPKVLSQIGPGILWLGALLAGLLNLNKLFQTDHDDGNLDQF
ILSGQRQSFTLIVLTKCLAHWVGTMLPLIFATPFLAFMLHLDAIITFTTILTLLCGTPAIIFIGAIGAALATSLLHSTLL
IFIIILPWIIPIMIFGVSAATAPTNPNVSFLTSLTLLIGFSLLLSLFSSFIAAITLKLLSE
>Mature_221_residues
MKALFWRDLKLTLAPQASSLKGLLFFIAIIMIIPFAIGPNPKVLSQIGPGILWLGALLAGLLNLNKLFQTDHDDGNLDQF
ILSGQRQSFTLIVLTKCLAHWVGTMLPLIFATPFLAFMLHLDAIITFTTILTLLCGTPAIIFIGAIGAALATSLLHSTLL
IFIIILPWIIPIMIFGVSAATAPTNPNVSFLTSLTLLIGFSLLLSLFSSFIAAITLKLLSE

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG2386

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmB/CycW/HelB family [H]

Homologues:

Organism=Escherichia coli, GI1788528, Length=212, Percent_Identity=37.2641509433962, Blast_Score=94, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003544 [H]

Pfam domain/function: PF03379 CcmB [H]

EC number: NA

Molecular weight: Translated: 23871; Mature: 23871

Theoretical pI: Translated: 8.80; Mature: 8.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALFWRDLKLTLAPQASSLKGLLFFIAIIMIIPFAIGPNPKVLSQIGPGILWLGALLAG
CCCHHHHCHHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHH
LLNLNKLFQTDHDDGNLDQFILSGQRQSFTLIVLTKCLAHWVGTMLPLIFATPFLAFMLH
HHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDAIITFTTILTLLCGTPAIIFIGAIGAALATSLLHSTLLIFIIILPWIIPIMIFGVSAA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TAPTNPNVSFLTSLTLLIGFSLLLSLFSSFIAAITLKLLSE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKALFWRDLKLTLAPQASSLKGLLFFIAIIMIIPFAIGPNPKVLSQIGPGILWLGALLAG
CCCHHHHCHHEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCHHHHHHHHHHH
LLNLNKLFQTDHDDGNLDQFILSGQRQSFTLIVLTKCLAHWVGTMLPLIFATPFLAFMLH
HHHHHHHHHCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDAIITFTTILTLLCGTPAIIFIGAIGAALATSLLHSTLLIFIIILPWIIPIMIFGVSAA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
TAPTNPNVSFLTSLTLLIGFSLLLSLFSSFIAAITLKLLSE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]