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The map label for this gene is ccmC [H]

Identifier: 49474931

GI number: 49474931

Start: 152497

End: 153252

Strand: Reverse

Name: ccmC [H]

Synonym: BH01130

Alternate gene names: 49474931

Gene position: 153252-152497 (Counterclockwise)

Preceding gene: 49474932

Following gene: 49474930

Centisome position: 7.94

GC content: 40.61

Gene sequence:

>756_bases
ATGAATGAAACATTTCACACACATAAAATGAACACGCTTCCTGCAAGTTTTACCCGTTTCATGAAAATAAGCAGTGCCGT
TTTGCCTTGGTTAATCGGTATAACATTGTGTCTTCTTATCTTAGGATTTATTTTGATTATATATTCTCCTGATGACTATC
AACAGGGGATCACCGTCAAGATTATGTACATTCATGCACCATTCGCTTGGCTTTCTACATGTTGTTACATCATAATAAGT
GCTGCTGCTTTAGGAAGCCTGATTTGGAAGTATCATCTTGCTGATGTGACACTCAAATGTGGCGCACCCATTGGAGCAAT
TTTTACAGCCTTGGCCCTAGTGACAGGTGCACTTTGGGGACGTCCTACATGGGGAACATGGTGGGTATGGGATGCACGGT
TAACATCAGTTTTGATCCTGCTTTTTATCTACCTTGCCATTGTCATGCTTGCTCGCGCTTTTAATAACCAAGCAAAAGCT
GCACGCGCTACCGCAATTCTGACACTCGTTGGACTTGTAAATATTCCCATTATTAAATTTTCCGTCAATTGGTGGAATAC
ACTTCATCAATCAGCATCACTTTTACGTGCAGGAGGCCCAACAATTGAACGTGCTATGTTATGGCCCCTTATAACAATGC
TATTGTGTTTTAGCTTTATGTTTATTTCGCTTTATTTGATGGCTATGCGTAACGAAATCAATAGTCGTCATATCCAAATA
CTTCAGATCAAAAAAGCCCGTCGTGCACAACACTAG

Upstream 100 bases:

>100_bases
AGTCTTTTTAGCTCCTTTATTGCAGCTATAACACTCAAACTTTTATCAGAATAATAAAAGATGATTGCTGCACAACAAAA
CTCTGCCTATTATAAATTTC

Downstream 100 bases:

>100_bases
GACTCGTTAATCATGTTCGACTTCCATAACATGCACAGTGGATTTTTAGGAAATCTCTCTCAGCAAATTGATTTTTTCCT
TGGTACTCTTCATCACAAAC

Product: Heme exporter protein C

Products: NA

Alternate protein names: Cytochrome c-type biogenesis protein CycZ [H]

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MNETFHTHKMNTLPASFTRFMKISSAVLPWLIGITLCLLILGFILIIYSPDDYQQGITVKIMYIHAPFAWLSTCCYIIIS
AAALGSLIWKYHLADVTLKCGAPIGAIFTALALVTGALWGRPTWGTWWVWDARLTSVLILLFIYLAIVMLARAFNNQAKA
ARATAILTLVGLVNIPIIKFSVNWWNTLHQSASLLRAGGPTIERAMLWPLITMLLCFSFMFISLYLMAMRNEINSRHIQI
LQIKKARRAQH

Sequences:

>Translated_251_residues
MNETFHTHKMNTLPASFTRFMKISSAVLPWLIGITLCLLILGFILIIYSPDDYQQGITVKIMYIHAPFAWLSTCCYIIIS
AAALGSLIWKYHLADVTLKCGAPIGAIFTALALVTGALWGRPTWGTWWVWDARLTSVLILLFIYLAIVMLARAFNNQAKA
ARATAILTLVGLVNIPIIKFSVNWWNTLHQSASLLRAGGPTIERAMLWPLITMLLCFSFMFISLYLMAMRNEINSRHIQI
LQIKKARRAQH
>Mature_251_residues
MNETFHTHKMNTLPASFTRFMKISSAVLPWLIGITLCLLILGFILIIYSPDDYQQGITVKIMYIHAPFAWLSTCCYIIIS
AAALGSLIWKYHLADVTLKCGAPIGAIFTALALVTGALWGRPTWGTWWVWDARLTSVLILLFIYLAIVMLARAFNNQAKA
ARATAILTLVGLVNIPIIKFSVNWWNTLHQSASLLRAGGPTIERAMLWPLITMLLCFSFMFISLYLMAMRNEINSRHIQI
LQIKKARRAQH

Specific function: Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes [H]

COG id: COG0755

COG function: function code O; ABC-type transport system involved in cytochrome c biogenesis, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmC/CycZ/HelC family [H]

Homologues:

Organism=Escherichia coli, GI1788527, Length=236, Percent_Identity=41.9491525423729, Blast_Score=184, Evalue=7e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002541
- InterPro:   IPR003557 [H]

Pfam domain/function: PF01578 Cytochrom_C_asm [H]

EC number: NA

Molecular weight: Translated: 28340; Mature: 28340

Theoretical pI: Translated: 10.37; Mature: 10.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
6.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNETFHTHKMNTLPASFTRFMKISSAVLPWLIGITLCLLILGFILIIYSPDDYQQGITVK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEE
IMYIHAPFAWLSTCCYIIISAAALGSLIWKYHLADVTLKCGAPIGAIFTALALVTGALWG
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHCC
RPTWGTWWVWDARLTSVLILLFIYLAIVMLARAFNNQAKAARATAILTLVGLVNIPIIKF
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEE
SVNWWNTLHQSASLLRAGGPTIERAMLWPLITMLLCFSFMFISLYLMAMRNEINSRHIQI
EHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEH
LQIKKARRAQH
EEEHHHHCCCC
>Mature Secondary Structure
MNETFHTHKMNTLPASFTRFMKISSAVLPWLIGITLCLLILGFILIIYSPDDYQQGITVK
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCEEE
IMYIHAPFAWLSTCCYIIISAAALGSLIWKYHLADVTLKCGAPIGAIFTALALVTGALWG
EEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHCC
RPTWGTWWVWDARLTSVLILLFIYLAIVMLARAFNNQAKAARATAILTLVGLVNIPIIKF
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCEEEE
SVNWWNTLHQSASLLRAGGPTIERAMLWPLITMLLCFSFMFISLYLMAMRNEINSRHIQI
EHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEH
LQIKKARRAQH
EEEHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1850420; 12597275 [H]