Click here to switch to the map view.

The map label for this gene is yggV [C]

Identifier: 49474878

GI number: 49474878

Start: 77425

End: 78072

Strand: Reverse

Name: yggV [C]

Synonym: BH00540

Alternate gene names: 49474878

Gene position: 78072-77425 (Counterclockwise)

Preceding gene: 49474881

Following gene: 49474877

Centisome position: 4.04

GC content: 40.59

Gene sequence:

>648_bases
ATGAGAAGCATAGCAAACAAAAAGCTCGTCATTGCTACACATAATATTGGCAAATTGCAGGAAATTACCACCTTGGTTGC
TCCCTTTGGTTTAACAATACAATCAGCCAAAGAGCTCGGATTACCTGAACCAAAAGAAACAGGAACAACATTTGAAGAAA
ATGCTTATATCAAAGCCTTTGCAGCTGCAAAAAATACAGGACTTCCTGCCCTCTCTGATGATTCAGGATTAGAAGTGGAT
GCACTGAATGGTGCACCAGGTGTTTATACCGCTGATCTCGCTCTTCAATCCGATGGTACACGCGACTTTTTAAAAGCTAT
GCAAAAAATAGAAGAGAAACTCCAAAAAATCGGAGCACATAAAAAAAGCCAACGAAAATGCCGGTTTATATCGGTTATAT
GCATTGCATGGCCCGATGCTCATGCAGATTATTTCCACGGACGTGTTGAAGGGTCATTCATTTGGCCACCACGTGGAGAT
AAGGGTTTTGGCTTTGATCCCGTTTTTTTACCAGATGGATATAAAAATACCTTTGGTGAAATGACAACGGAGCAAAAACA
TGGTTGGAAACTCAATGATCAAACACCGCTCTCTCATCGTGCATGTGCCTTCAAACTTTTAGCAGAAAACCTTTTAAAAC
TCTCATGA

Upstream 100 bases:

>100_bases
TATATCTCGTAAAATCTGGCAGAACTCATATTATATGTTCGTTTAAACTGATTTTTAGTCCAGAAAATAACACCCTCCTT
TCATTTTTAGAGAGACGTAT

Downstream 100 bases:

>100_bases
ATGAACCTTTTGGCATCTACATCCATTGGCCCTTTTGCGCTGCCAAATGTCCTTATTGTGACTTTAATTCGCATGTTCGC
CTTCATGGTGTTGATCAACC

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase

Number of amino acids: Translated: 215; Mature: 215

Protein sequence:

>215_residues
MRSIANKKLVIATHNIGKLQEITTLVAPFGLTIQSAKELGLPEPKETGTTFEENAYIKAFAAAKNTGLPALSDDSGLEVD
ALNGAPGVYTADLALQSDGTRDFLKAMQKIEEKLQKIGAHKKSQRKCRFISVICIAWPDAHADYFHGRVEGSFIWPPRGD
KGFGFDPVFLPDGYKNTFGEMTTEQKHGWKLNDQTPLSHRACAFKLLAENLLKLS

Sequences:

>Translated_215_residues
MRSIANKKLVIATHNIGKLQEITTLVAPFGLTIQSAKELGLPEPKETGTTFEENAYIKAFAAAKNTGLPALSDDSGLEVD
ALNGAPGVYTADLALQSDGTRDFLKAMQKIEEKLQKIGAHKKSQRKCRFISVICIAWPDAHADYFHGRVEGSFIWPPRGD
KGFGFDPVFLPDGYKNTFGEMTTEQKHGWKLNDQTPLSHRACAFKLLAENLLKLS
>Mature_215_residues
MRSIANKKLVIATHNIGKLQEITTLVAPFGLTIQSAKELGLPEPKETGTTFEENAYIKAFAAAKNTGLPALSDDSGLEVD
ALNGAPGVYTADLALQSDGTRDFLKAMQKIEEKLQKIGAHKKSQRKCRFISVICIAWPDAHADYFHGRVEGSFIWPPRGD
KGFGFDPVFLPDGYKNTFGEMTTEQKHGWKLNDQTPLSHRACAFKLLAENLLKLS

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family

Homologues:

Organism=Homo sapiens, GI15626999, Length=209, Percent_Identity=28.2296650717703, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1789324, Length=210, Percent_Identity=39.5238095238095, Blast_Score=130, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17556833, Length=205, Percent_Identity=29.2682926829268, Blast_Score=70, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322529, Length=216, Percent_Identity=28.2407407407407, Blast_Score=68, Evalue=9e-13,
Organism=Drosophila melanogaster, GI19920712, Length=211, Percent_Identity=31.2796208530806, Blast_Score=75, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NTPA_BARHE (Q6G565)

Other databases:

- EMBL:   BX897699
- RefSeq:   YP_032919.1
- ProteinModelPortal:   Q6G565
- SMR:   Q6G565
- GeneID:   2865975
- GenomeReviews:   BX897699_GR
- KEGG:   bhe:BH00540
- NMPDR:   fig|283166.1.peg.47
- HOGENOM:   HBG697237
- OMA:   VYTADWA
- PhylomeDB:   Q6G565
- ProtClustDB:   PRK00120
- BioCyc:   BHEN283166:BH00540-MONOMER
- BRENDA:   3.6.1.15
- HAMAP:   MF_01405
- InterPro:   IPR002637
- InterPro:   IPR020922
- PANTHER:   PTHR11067

Pfam domain/function: PF01725 Ham1p_like

EC number: =3.6.1.15

Molecular weight: Translated: 23662; Mature: 23662

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSIANKKLVIATHNIGKLQEITTLVAPFGLTIQSAKELGLPEPKETGTTFEENAYIKAF
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEHHHHHCCCCCCCCCCCCCCCCCEEEEE
AAAKNTGLPALSDDSGLEVDALNGAPGVYTADLALQSDGTRDFLKAMQKIEEKLQKIGAH
EHHCCCCCCCCCCCCCCEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
KKSQRKCRFISVICIAWPDAHADYFHGRVEGSFIWPPRGDKGFGFDPVFLPDGYKNTFGE
CCHHCCCEEEEEEEEECCCCCCHHHCCEECCEEECCCCCCCCCCCCCEECCCCCCHHHHH
MTTEQKHGWKLNDQTPLSHRACAFKLLAENLLKLS
CCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRSIANKKLVIATHNIGKLQEITTLVAPFGLTIQSAKELGLPEPKETGTTFEENAYIKAF
CCCCCCCEEEEEECCCCHHHHHHHHHHCCCCEEHHHHHCCCCCCCCCCCCCCCCCEEEEE
AAAKNTGLPALSDDSGLEVDALNGAPGVYTADLALQSDGTRDFLKAMQKIEEKLQKIGAH
EHHCCCCCCCCCCCCCCEEEECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCC
KKSQRKCRFISVICIAWPDAHADYFHGRVEGSFIWPPRGDKGFGFDPVFLPDGYKNTFGE
CCHHCCCEEEEEEEEECCCCCCHHHCCEECCEEECCCCCCCCCCCCCEECCCCCCHHHHH
MTTEQKHGWKLNDQTPLSHRACAFKLLAENLLKLS
CCCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA