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The map label for this gene is infC

Identifier: 49474873

GI number: 49474873

Start: 72362

End: 72880

Strand: Reverse

Name: infC

Synonym: BH00490

Alternate gene names: 49474873

Gene position: 72880-72362 (Counterclockwise)

Preceding gene: 49474877

Following gene: 49474872

Centisome position: 3.77

GC content: 38.73

Gene sequence:

>519_bases
ATGACACATACCCCAAAAGATGGGCCACGTGCAAATCAAGATATTCGGGTTCCTCGCGTTCAACTTATTAATGATGAGGG
GCAACATCAAGGAGTGGTTACAATACAAGAAGCTCTTGCTATGGCTGCAGAAGTCGGCCTTGATTTGGTTGAAATTGTAC
CAAATGCAGAACCTCCTGTGTGTAAAATTATCGATTTGGGCAAATTGAAATATCAGACCCAAAAAAAAGCGGCTGAAACA
CGTAAAAAACAAAAAGTCATTGAGATTAAAGAAATTAAGATGCGTCCAAATGTTGATGTTCATGATTATGGAGTCAAGCT
CAAGGCTATTCATCGTTTTATTGGTAATGGCGATAAAGTAAAGATTACTTTGCGTTTTCGTGGACGTGAAATGGCACACC
AAGATCTTGGATTAAAGCTTCTTCAGCGAGTTAAAGAAGATACAAGTGAAATTGCTAAAATCGAATCTGAGCCAAAACTC
GAAGGTCGTCAAATGATGATGGTGATAGCAGCTAAATAA

Upstream 100 bases:

>100_bases
AGCATGAATTCTAGTTGTTTTTCTGTGTATAATTGTATATTAAATTGTATTGTAGGTGAATCAAAATTAAGGAGCGTAAA
CCATTCGCAAACCATTTAAA

Downstream 100 bases:

>100_bases
TTTTTCATGGGAGTAATATAGAGAATACAACTCATCTAGAGTTGGTTTAGGAATATGATTTAAAAGTGCCACGTAAGGCA
GGTGGTGCTTTTAAGGGTTT

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MTHTPKDGPRANQDIRVPRVQLINDEGQHQGVVTIQEALAMAAEVGLDLVEIVPNAEPPVCKIIDLGKLKYQTQKKAAET
RKKQKVIEIKEIKMRPNVDVHDYGVKLKAIHRFIGNGDKVKITLRFRGREMAHQDLGLKLLQRVKEDTSEIAKIESEPKL
EGRQMMMVIAAK

Sequences:

>Translated_172_residues
MTHTPKDGPRANQDIRVPRVQLINDEGQHQGVVTIQEALAMAAEVGLDLVEIVPNAEPPVCKIIDLGKLKYQTQKKAAET
RKKQKVIEIKEIKMRPNVDVHDYGVKLKAIHRFIGNGDKVKITLRFRGREMAHQDLGLKLLQRVKEDTSEIAKIESEPKL
EGRQMMMVIAAK
>Mature_171_residues
THTPKDGPRANQDIRVPRVQLINDEGQHQGVVTIQEALAMAAEVGLDLVEIVPNAEPPVCKIIDLGKLKYQTQKKAAETR
KKQKVIEIKEIKMRPNVDVHDYGVKLKAIHRFIGNGDKVKITLRFRGREMAHQDLGLKLLQRVKEDTSEIAKIESEPKLE
GRQMMMVIAAK

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family

Homologues:

Organism=Escherichia coli, GI1788012, Length=164, Percent_Identity=57.3170731707317, Blast_Score=175, Evalue=1e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IF3_BARHE (Q6G570)

Other databases:

- EMBL:   BX897699
- RefSeq:   YP_032914.1
- ProteinModelPortal:   Q6G570
- GeneID:   2865561
- GenomeReviews:   BX897699_GR
- KEGG:   bhe:BH00490
- NMPDR:   fig|283166.1.peg.42
- HOGENOM:   HBG744268
- OMA:   APKAPIN
- PhylomeDB:   Q6G570
- ProtClustDB:   PRK00028
- BioCyc:   BHEN283166:BH00490-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00080
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814
- Gene3D:   G3DSA:3.10.20.80
- Gene3D:   G3DSA:3.30.110.10
- PANTHER:   PTHR10938
- TIGRFAMs:   TIGR00168

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N; SSF54364 IF3; SSF55200 IF3

EC number: NA

Molecular weight: Translated: 19432; Mature: 19301

Theoretical pI: Translated: 10.18; Mature: 10.18

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTHTPKDGPRANQDIRVPRVQLINDEGQHQGVVTIQEALAMAAEVGLDLVEIVPNAEPPV
CCCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHCCHHEECCCCCCCCE
CKIIDLGKLKYQTQKKAAETRKKQKVIEIKEIKMRPNVDVHDYGVKLKAIHRFIGNGDKV
EEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHCCHHHHHHHHHCCCCEE
KITLRFRGREMAHQDLGLKLLQRVKEDTSEIAKIESEPKLEGRQMMMVIAAK
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECC
>Mature Secondary Structure 
THTPKDGPRANQDIRVPRVQLINDEGQHQGVVTIQEALAMAAEVGLDLVEIVPNAEPPV
CCCCCCCCCCCCCCCCCEEEEECCCCCCCCEEHHHHHHHHHHHHCCHHEECCCCCCCCE
CKIIDLGKLKYQTQKKAAETRKKQKVIEIKEIKMRPNVDVHDYGVKLKAIHRFIGNGDKV
EEEEECCCHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCHHHCCHHHHHHHHHCCCCEE
KITLRFRGREMAHQDLGLKLLQRVKEDTSEIAKIESEPKLEGRQMMMVIAAK
EEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA