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The map label for this gene is yisV [H]

Identifier: 49185558

GI number: 49185558

Start: 2553057

End: 2554490

Strand: Direct

Name: yisV [H]

Synonym: BAS2550

Alternate gene names: 49185558

Gene position: 2553057-2554490 (Clockwise)

Preceding gene: 49185555

Following gene: 49185559

Centisome position: 48.83

GC content: 33.68

Gene sequence:

>1434_bases
ATGAAGATTGTACTGCGTAAAGAATCCAACATACCGTATTACAAGCAAATATATATGCAAATCGTTGAAAGAATACAAAG
TGGCATGCTTTCGCATGGTGACTCACTTCCATCTTTACGCTCTATGGCCGAAGATTTACAGATTAACCTATTAACTGTTC
GTAAGGCGTATAAACATCTGGAAAAGAAAGAATATATACGCATTGAACAAGGTAAAGGTGCTTATATACATAAACATGTA
AAAAAAGATTCTAAACCAATTCCGTATAAATGGCAACAAACGAAAACGATTAATGTTATGCGATCTCAATATGCAATGAA
TCAGCACCGGAAATATTACGATTTTTCACAAGCGATTTTGTATCCTCGTCTATTGCCAAATCCATTCTTGGCAGACGAAA
TGCATAAAATACTTAATAAAGACAAGATGATTCTAGCAACATATGGACCAGTTCAAGGAGATTATGAACTACGAGTTGAA
ATAGCAAATTACTTAAATGAACATCAAAAATTAGTGACAGACCCATCCCAGTTATTAATTACAAGCGGCGCACAACAAGG
AATTGATTTAATTGCTCAAACACTATTAAAACCTGGTGATATTGTGTTAGTGGAAAGTCCGTGTTATAGTGCTGCGCTTG
ATATTTTCATCAATAAAGGAGCTCAAATTATACCTGTTTCTCTAGATAATCATGGGGTTCGATCCGATTTAATCGATGAT
ATTTGTCAAAGTAAAAATCCCGTTTTATTGTATACGAATCCAACTTTCCAGAACCCGACAGGTACAGTAATGAGTAAAGA
ACGAAGAATGGAACTTATAGAACTAGCGGAGCTATATGAGTTTTTTATAATTGAAGATGATTCTTTCGGAGAAATATATT
TTGAAGATGCTATTGTTCCCCCTCCTATCAAAAATTTTGATACAAACGGACACGTACTATATATAAAAGGATTTAGTAAA
ACGTTAGCACCAGGACTGCGTATCGCATCTCTTATTGCCGATGGTCCTATTTTCGCATGGTTATATGCCGTAAAAGGTTC
GATGGATATCGGTAGCCCTTTATTAACACAAAAAGCACTTCTACCGTTTTTACGTGCAGAACGTATGAAACATCATTTAG
AAAAATTACGTACAGCTTTACAAATTAGACGTGATATAACGATTGATATGTTATCACCACTTAAAGAAATACAATTTGAA
ATACCTGATGGTGGCTTTAATTTATGGATTACTCTTCCTAATTCGATAGATCCCTTTACCTTATTACAAAAAGCAAATGA
AGTAGATGTTTCTTTTTTACCAGGAACAGCTTGTCTATTACATAACGATATAAACAATAACCAATTCAGGATTAGCTATT
CTATGTTAAATGAAAAAGATATGTTGATTGGTTTAGAGAAATTACATGACACAATACGAAAATTTAAGCTATAA

Upstream 100 bases:

>100_bases
GTATAACAGTGTATCTATGTATATAACAGTTGCCTAAAATAGTAGTTGATTCTCTTTATATTTTTCGCTTAAATTAAATA
AAAACGAAAAAGGTGAAACC

Downstream 100 bases:

>100_bases
AAGCATATGCACAATATCTTTAAGCTAAAAAGTAAATCCCCCAAAACATTTTAGTTTTGGGGGATAATGAAATTTTGAAA
GATACTTAATCATTTTCATT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 477; Mature: 477

Protein sequence:

>477_residues
MKIVLRKESNIPYYKQIYMQIVERIQSGMLSHGDSLPSLRSMAEDLQINLLTVRKAYKHLEKKEYIRIEQGKGAYIHKHV
KKDSKPIPYKWQQTKTINVMRSQYAMNQHRKYYDFSQAILYPRLLPNPFLADEMHKILNKDKMILATYGPVQGDYELRVE
IANYLNEHQKLVTDPSQLLITSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDIFINKGAQIIPVSLDNHGVRSDLIDD
ICQSKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYEFFIIEDDSFGEIYFEDAIVPPPIKNFDTNGHVLYIKGFSK
TLAPGLRIASLIADGPIFAWLYAVKGSMDIGSPLLTQKALLPFLRAERMKHHLEKLRTALQIRRDITIDMLSPLKEIQFE
IPDGGFNLWITLPNSIDPFTLLQKANEVDVSFLPGTACLLHNDINNNQFRISYSMLNEKDMLIGLEKLHDTIRKFKL

Sequences:

>Translated_477_residues
MKIVLRKESNIPYYKQIYMQIVERIQSGMLSHGDSLPSLRSMAEDLQINLLTVRKAYKHLEKKEYIRIEQGKGAYIHKHV
KKDSKPIPYKWQQTKTINVMRSQYAMNQHRKYYDFSQAILYPRLLPNPFLADEMHKILNKDKMILATYGPVQGDYELRVE
IANYLNEHQKLVTDPSQLLITSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDIFINKGAQIIPVSLDNHGVRSDLIDD
ICQSKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYEFFIIEDDSFGEIYFEDAIVPPPIKNFDTNGHVLYIKGFSK
TLAPGLRIASLIADGPIFAWLYAVKGSMDIGSPLLTQKALLPFLRAERMKHHLEKLRTALQIRRDITIDMLSPLKEIQFE
IPDGGFNLWITLPNSIDPFTLLQKANEVDVSFLPGTACLLHNDINNNQFRISYSMLNEKDMLIGLEKLHDTIRKFKL
>Mature_477_residues
MKIVLRKESNIPYYKQIYMQIVERIQSGMLSHGDSLPSLRSMAEDLQINLLTVRKAYKHLEKKEYIRIEQGKGAYIHKHV
KKDSKPIPYKWQQTKTINVMRSQYAMNQHRKYYDFSQAILYPRLLPNPFLADEMHKILNKDKMILATYGPVQGDYELRVE
IANYLNEHQKLVTDPSQLLITSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDIFINKGAQIIPVSLDNHGVRSDLIDD
ICQSKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYEFFIIEDDSFGEIYFEDAIVPPPIKNFDTNGHVLYIKGFSK
TLAPGLRIASLIADGPIFAWLYAVKGSMDIGSPLLTQKALLPFLRAERMKHHLEKLRTALQIRRDITIDMLSPLKEIQFE
IPDGGFNLWITLPNSIDPFTLLQKANEVDVSFLPGTACLLHNDINNNQFRISYSMLNEKDMLIGLEKLHDTIRKFKL

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=323, Percent_Identity=29.4117647058824, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI33469970, Length=323, Percent_Identity=29.4117647058824, Blast_Score=117, Evalue=2e-26,
Organism=Escherichia coli, GI1790797, Length=437, Percent_Identity=26.0869565217391, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1787710, Length=439, Percent_Identity=28.7015945330296, Blast_Score=149, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6321236, Length=384, Percent_Identity=25.2604166666667, Blast_Score=91, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6321929, Length=195, Percent_Identity=24.1025641025641, Blast_Score=75, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6321000, Length=380, Percent_Identity=25, Blast_Score=70, Evalue=7e-13,
Organism=Drosophila melanogaster, GI21356535, Length=366, Percent_Identity=26.5027322404372, Blast_Score=115, Evalue=8e-26,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54695; Mature: 54695

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIVLRKESNIPYYKQIYMQIVERIQSGMLSHGDSLPSLRSMAEDLQINLLTVRKAYKHL
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEHHHHHHHHHHC
EKKEYIRIEQGKGAYIHKHVKKDSKPIPYKWQQTKTINVMRSQYAMNQHRKYYDFSQAIL
CHHCCEEEECCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YPRLLPNPFLADEMHKILNKDKMILATYGPVQGDYELRVEIANYLNEHQKLVTDPSQLLI
HHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEEHHHHHHHHHHHHHCCCHHHEE
TSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDIFINKGAQIIPVSLDNHGVRSDLIDD
ECCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
ICQSKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYEFFIIEDDSFGEIYFEDAIVP
HHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCC
PPIKNFDTNGHVLYIKGFSKTLAPGLRIASLIADGPIFAWLYAVKGSMDIGSPLLTQKAL
CCCCCCCCCCCEEEEECCCHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHH
LPFLRAERMKHHLEKLRTALQIRRDITIDMLSPLKEIQFEIPDGGFNLWITLPNSIDPFT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHCEEECCCCCEEEEEECCCCCCHHH
LLQKANEVDVSFLPGTACLLHNDINNNQFRISYSMLNEKDMLIGLEKLHDTIRKFKL
HHHCCCCCCEEECCCCEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKIVLRKESNIPYYKQIYMQIVERIQSGMLSHGDSLPSLRSMAEDLQINLLTVRKAYKHL
CEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHEEEHHHHHHHHHHC
EKKEYIRIEQGKGAYIHKHVKKDSKPIPYKWQQTKTINVMRSQYAMNQHRKYYDFSQAIL
CHHCCEEEECCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
YPRLLPNPFLADEMHKILNKDKMILATYGPVQGDYELRVEIANYLNEHQKLVTDPSQLLI
HHHHCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCEEEEHHHHHHHHHHHHHCCCHHHEE
TSGAQQGIDLIAQTLLKPGDIVLVESPCYSAALDIFINKGAQIIPVSLDNHGVRSDLIDD
ECCCHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHH
ICQSKNPVLLYTNPTFQNPTGTVMSKERRMELIELAELYEFFIIEDDSFGEIYFEDAIVP
HHCCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCCC
PPIKNFDTNGHVLYIKGFSKTLAPGLRIASLIADGPIFAWLYAVKGSMDIGSPLLTQKAL
CCCCCCCCCCCEEEEECCCHHHCCHHHHHHHHHCCHHHHHHHHHCCCCCCCCHHHHHHHH
LPFLRAERMKHHLEKLRTALQIRRDITIDMLSPLKEIQFEIPDGGFNLWITLPNSIDPFT
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHCEEECCCCCEEEEEECCCCCCHHH
LLQKANEVDVSFLPGTACLLHNDINNNQFRISYSMLNEKDMLIGLEKLHDTIRKFKL
HHHCCCCCCEEECCCCEEEEECCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]