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The map label for this gene is yqgF [H]

Identifier: 49185336

GI number: 49185336

Start: 2326546

End: 2328297

Strand: Direct

Name: yqgF [H]

Synonym: BAS2327

Alternate gene names: 49185336

Gene position: 2326546-2328297 (Clockwise)

Preceding gene: 49185335

Following gene: 49185337

Centisome position: 44.5

GC content: 35.05

Gene sequence:

>1752_bases
ATGCAGTTGAATACGAAACGTGCGGATACAAAGATTACTAAAAAAGATATAGAAAAGTTTAAAGAAAAGGGAATAGAGGG
AAAAGAGTTAGATAAAAAAATAGAAGATTTAAGACGAAGTCGCGTTACAGAAGTAGAATTGGGTGAATTAACAGAACAAG
ATTTAAAGGTGTTAGCTATTAAAAGTAAAATGAGTTCAGGTTATCAACTAACACCACAAATTATTAAAAAAGATGTAACA
GATGAGGAGTATGCACGGATAAGTGAAAATCTTGCGAATTTTCCAGGAGTAGATGCAACGGTTGATTGGGAACGTAATTA
TGTAAATGGTAATTTGTTTCGTTCCGTATTAGGTAATATTACGAGTAGTGAAGAAGGTCTGCCGAAAGAAAACTTAGATT
CTTATTTGGTACGCGGATATAACCGTAATGACCGTGTCGGAAAAAGTTATATTGAACAACGATATGAAGATGTATTACAT
GGCACAAAAGAAGAAGTGAAAAACATTACTGATAAATCAGGAAACATTATAAATACAGAAGTAATCGCTAAAGGAAAAAG
TGGTAAAAGTTTAACATTAACGATTGATATGGAATTACAAAAGAAAGTGGAAGAAAGTATAGAGAAAAACTTGAGAGCTT
TTAAGAGTTCAGAGCCGCTACTCGATCGAGCTTTTGTCGTCATGACGAATCCAAATAACGGACAGATTTTATCTATGGCA
GGCAAAAAGATTGTAGAAAAAGAAGGAGTACTAGAGATTGAGGATTTGGCATTAGGCAATATGACAACTTCGTATGAGCT
AGGCTCTGCTGTAAAAGGTGCTACTTTATTAACTGGATATGAGACAGGAGCAATACATCCAGGAGATCAATTTTATGATG
CACCGATGAAATTTAAAGGTACACAAGCTAAGAAATCGTGGAATGTATCTGGATTTGGTAATATTAATGATTTACGAGCT
TTACAAGTATCTTCGAATGTATACATGTTCCAGACAGCTTTAAAAATTGCGGGAGTTAATTACGTACCAAATGGCTCATT
GGATATTAAACAAGGAGCATTTGATACGATGCGCTATTATTTCAAGCAATTTGGTTTAGGAGTCCCAACAGGTATCGATT
TACCGAATGAAATAATTGGACAAACTAGAAAAGTAGATAGTCAACCTGGATTTTTACTAGACTTTTCCATCGGTCAGTAT
GATACGTATACGCCGTTGCAATTAGCTCAATATATTTCAACGATTGCGAATGGTGGTTATAGAATGCAACCTCAAATTGT
ACAAGAAATACGAGAACAATCAATTAAAGAAGAGGTTGGTAAAGTTATTCGCTCTATAGAGCCTGTAGTATTAAATCGGA
TTGATATGAAGACAGAATATATTGATCGAATAAAAGAAGGGTTTAGATGGGTATTCCAAGAAGGGGATGGAACTGGCGTA
AAGCATTTCAAAAATGCTCCATATAAACCAGCAGGAAAGACAGGGACAGCCCAAACTGTGTATGGTGGAGATGATCCAAT
TGGTAGAAATGCAAAAGGAGAACGTATGGAATGTTACAACTTAACGTTAGTTGGATATGCTCCATATGATAATCCAGAAG
TAGCGTTTTCTGTAGTAGTCCCATGGCTTCATAATGATAAAAGTGGAATTAATTCTATAATCGGAAAGGAAGTTTTAGAT
GTATACTTTGATTTGAAAAAGCAGCGTATGCATGATGAAGCTGCTAGTACAGATACTTCGAATCAAAATTAG

Upstream 100 bases:

>100_bases
GTGACGATATTTTAAAAACAGCAAAAGACTTGGCGAAAGTACTTGAAATGCCTGAACAAGATATTAATAAATTAACTGAT
ATCGATAAAAAGATTTTTGG

Downstream 100 bases:

>100_bases
TAAAATTTGTGTACTTTTCTCAGGGAAGAACCCCTGTTTGTATAAAGGCATTTATAAGTAAAAAGATGAAATGTGAAATA
AGAGATAGCAGCGGTCATAG

Product: penicillin-binding protein, C-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MQLNTKRADTKITKKDIEKFKEKGIEGKELDKKIEDLRRSRVTEVELGELTEQDLKVLAIKSKMSSGYQLTPQIIKKDVT
DEEYARISENLANFPGVDATVDWERNYVNGNLFRSVLGNITSSEEGLPKENLDSYLVRGYNRNDRVGKSYIEQRYEDVLH
GTKEEVKNITDKSGNIINTEVIAKGKSGKSLTLTIDMELQKKVEESIEKNLRAFKSSEPLLDRAFVVMTNPNNGQILSMA
GKKIVEKEGVLEIEDLALGNMTTSYELGSAVKGATLLTGYETGAIHPGDQFYDAPMKFKGTQAKKSWNVSGFGNINDLRA
LQVSSNVYMFQTALKIAGVNYVPNGSLDIKQGAFDTMRYYFKQFGLGVPTGIDLPNEIIGQTRKVDSQPGFLLDFSIGQY
DTYTPLQLAQYISTIANGGYRMQPQIVQEIREQSIKEEVGKVIRSIEPVVLNRIDMKTEYIDRIKEGFRWVFQEGDGTGV
KHFKNAPYKPAGKTGTAQTVYGGDDPIGRNAKGERMECYNLTLVGYAPYDNPEVAFSVVVPWLHNDKSGINSIIGKEVLD
VYFDLKKQRMHDEAASTDTSNQN

Sequences:

>Translated_583_residues
MQLNTKRADTKITKKDIEKFKEKGIEGKELDKKIEDLRRSRVTEVELGELTEQDLKVLAIKSKMSSGYQLTPQIIKKDVT
DEEYARISENLANFPGVDATVDWERNYVNGNLFRSVLGNITSSEEGLPKENLDSYLVRGYNRNDRVGKSYIEQRYEDVLH
GTKEEVKNITDKSGNIINTEVIAKGKSGKSLTLTIDMELQKKVEESIEKNLRAFKSSEPLLDRAFVVMTNPNNGQILSMA
GKKIVEKEGVLEIEDLALGNMTTSYELGSAVKGATLLTGYETGAIHPGDQFYDAPMKFKGTQAKKSWNVSGFGNINDLRA
LQVSSNVYMFQTALKIAGVNYVPNGSLDIKQGAFDTMRYYFKQFGLGVPTGIDLPNEIIGQTRKVDSQPGFLLDFSIGQY
DTYTPLQLAQYISTIANGGYRMQPQIVQEIREQSIKEEVGKVIRSIEPVVLNRIDMKTEYIDRIKEGFRWVFQEGDGTGV
KHFKNAPYKPAGKTGTAQTVYGGDDPIGRNAKGERMECYNLTLVGYAPYDNPEVAFSVVVPWLHNDKSGINSIIGKEVLD
VYFDLKKQRMHDEAASTDTSNQN
>Mature_583_residues
MQLNTKRADTKITKKDIEKFKEKGIEGKELDKKIEDLRRSRVTEVELGELTEQDLKVLAIKSKMSSGYQLTPQIIKKDVT
DEEYARISENLANFPGVDATVDWERNYVNGNLFRSVLGNITSSEEGLPKENLDSYLVRGYNRNDRVGKSYIEQRYEDVLH
GTKEEVKNITDKSGNIINTEVIAKGKSGKSLTLTIDMELQKKVEESIEKNLRAFKSSEPLLDRAFVVMTNPNNGQILSMA
GKKIVEKEGVLEIEDLALGNMTTSYELGSAVKGATLLTGYETGAIHPGDQFYDAPMKFKGTQAKKSWNVSGFGNINDLRA
LQVSSNVYMFQTALKIAGVNYVPNGSLDIKQGAFDTMRYYFKQFGLGVPTGIDLPNEIIGQTRKVDSQPGFLLDFSIGQY
DTYTPLQLAQYISTIANGGYRMQPQIVQEIREQSIKEEVGKVIRSIEPVVLNRIDMKTEYIDRIKEGFRWVFQEGDGTGV
KHFKNAPYKPAGKTGTAQTVYGGDDPIGRNAKGERMECYNLTLVGYAPYDNPEVAFSVVVPWLHNDKSGINSIIGKEVLD
VYFDLKKQRMHDEAASTDTSNQN

Specific function: Cell Wall Formation; Pbp-2 Is Responsible For The Determination Of The Rod Shape Of The Cell. Its Synthesize Cross- Linked Peptidoglycan From The Lipid Intermediates. [C]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=530, Percent_Identity=24.9056603773585, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1786272, Length=427, Percent_Identity=25.9953161592506, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 65308; Mature: 65308

Theoretical pI: Translated: 5.92; Mature: 5.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLNTKRADTKITKKDIEKFKEKGIEGKELDKKIEDLRRSRVTEVELGELTEQDLKVLAI
CCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHEEEE
KSKMSSGYQLTPQIIKKDVTDEEYARISENLANFPGVDATVDWERNYVNGNLFRSVLGNI
HHHHCCCCEECHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHCCC
TSSEEGLPKENLDSYLVRGYNRNDRVGKSYIEQRYEDVLHGTKEEVKNITDKSGNIINTE
CCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEE
VIAKGKSGKSLTLTIDMELQKKVEESIEKNLRAFKSSEPLLDRAFVVMTNPNNGQILSMA
EEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEECC
GKKIVEKEGVLEIEDLALGNMTTSYELGSAVKGATLLTGYETGAIHPGDQFYDAPMKFKG
CHHHHHHCCCEEEEEEEECCCCCCHHHCCCCCCCEEEECCCCCCCCCCCHHCCCCCCCCC
TQAKKSWNVSGFGNINDLRALQVSSNVYMFQTALKIAGVNYVPNGSLDIKQGAFDTMRYY
CCCCCCCCCCCCCCCCCCEEEEECCCEEEHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
FKQFGLGVPTGIDLPNEIIGQTRKVDSQPGFLLDFSIGQYDTYTPLQLAQYISTIANGGY
HHHHCCCCCCCCCCCHHHHCCHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCE
RMQPQIVQEIREQSIKEEVGKVIRSIEPVVLNRIDMKTEYIDRIKEGFRWVFQEGDGTGV
EECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCC
KHFKNAPYKPAGKTGTAQTVYGGDDPIGRNAKGERMECYNLTLVGYAPYDNPEVAFSVVV
HHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEEEEE
PWLHNDKSGINSIIGKEVLDVYFDLKKQRMHDEAASTDTSNQN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQLNTKRADTKITKKDIEKFKEKGIEGKELDKKIEDLRRSRVTEVELGELTEQDLKVLAI
CCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHCHHHHHEEEE
KSKMSSGYQLTPQIIKKDVTDEEYARISENLANFPGVDATVDWERNYVNGNLFRSVLGNI
HHHHCCCCEECHHHHHHCCCHHHHHHHHHHHHCCCCCCEEECCCCCCCCHHHHHHHHCCC
TSSEEGLPKENLDSYLVRGYNRNDRVGKSYIEQRYEDVLHGTKEEVKNITDKSGNIINTE
CCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCCCEEEEE
VIAKGKSGKSLTLTIDMELQKKVEESIEKNLRAFKSSEPLLDRAFVVMTNPNNGQILSMA
EEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEECC
GKKIVEKEGVLEIEDLALGNMTTSYELGSAVKGATLLTGYETGAIHPGDQFYDAPMKFKG
CHHHHHHCCCEEEEEEEECCCCCCHHHCCCCCCCEEEECCCCCCCCCCCHHCCCCCCCCC
TQAKKSWNVSGFGNINDLRALQVSSNVYMFQTALKIAGVNYVPNGSLDIKQGAFDTMRYY
CCCCCCCCCCCCCCCCCCEEEEECCCEEEHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHH
FKQFGLGVPTGIDLPNEIIGQTRKVDSQPGFLLDFSIGQYDTYTPLQLAQYISTIANGGY
HHHHCCCCCCCCCCCHHHHCCHHCCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCE
RMQPQIVQEIREQSIKEEVGKVIRSIEPVVLNRIDMKTEYIDRIKEGFRWVFQEGDGTGV
EECHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCC
KHFKNAPYKPAGKTGTAQTVYGGDDPIGRNAKGERMECYNLTLVGYAPYDNPEVAFSVVV
HHHCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEEEEE
PWLHNDKSGINSIIGKEVLDVYFDLKKQRMHDEAASTDTSNQN
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]