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The map label for this gene is penPC [H]

Identifier: 49185337

GI number: 49185337

Start: 2328549

End: 2329454

Strand: Direct

Name: penPC [H]

Synonym: BAS2328

Alternate gene names: 49185337

Gene position: 2328549-2329454 (Clockwise)

Preceding gene: 49185336

Following gene: 49185339

Centisome position: 44.53

GC content: 39.4

Gene sequence:

>906_bases
ATGCTAAAAATAGGGATGTGTGTTGGTATATTAGGTTTAAGTATTACAAGCCTAGTAACTTTTACAGGAGGTGCATTGCA
AGTTGAAGCGAAAGAAAAGACTGGACAAGTGAAACATAAAAATCAGGCGACGCATAAAGAGTTCTCTCAACTTGAGAAAA
AATTTGATGCTCGATTAGGTGTATATGCGATTGATACTGGTACAAATCAAACAATCGCTTATCGACCTAACGAAAGGTTT
GCCTTTGCATCAACTTACAAGGCTTTAGCGGCAGGGGTATTACTGCAACAGAACTCTACTAAGAAATTAGATGAAGTTAT
TACTTATACGAAAGAAGACTTAGTGGATTATTCACCTGTTACAGAGAAACATGTAGATACTGGAATGACACTAGGAGAAA
TTGCGGAGGCTGCTGTTCGTTACAGTGATAATACTGCAGGGAACATTTTATTTCATAAAATAGGCGGACCGAAAGGATAT
GAAAAAGCGCTTAGACAGATGGGGGACCGGGTTACTATGTCTGATCGTTTTGAAACAGAATTAAACGAGGCTATTCCAGG
AGACATTCGTGACACCAGTACAGCGAAAGCAATTGCTACGAATCTTAAAGCTTTTACGGCCGGAAATGCGCTTCCAAATC
ATAAACGTAACATTCTTACAAAGTGGATGAAAGGAAATGCTACAGGAGACAAACTTATTCGTGCAGGTGTGCCTACTAAC
TGGGTAGTTGCAGATAAATCAGGAGCTGGAAGTTACGGGACACGAAATGATATTGCTATCGTTTGGCCACCAAATAGAGC
ACCTATTATCATCGCAATTTTATCTAGTAAAGATGAAAAAGGGGCTACCTATGATAATCAACTCATTGCAGAGGCGGCTG
AAGTTATAGTTAATGCTTTTAGGTGA

Upstream 100 bases:

>100_bases
AAGTTTATGGAACAAATTTGTTTCGGTGATTGTCTATTATGTGTACGTATAAAAAGGTATTAAGTATTTGAAAGGAATGA
TAGTTTTGAAAAACAAGAAA

Downstream 100 bases:

>100_bases
TAATCTCTCAATTCTTTATGTAATGTAATTGAAAATATGAACTTGGAAAGCGATTCTTTTTAATATGAAAAGAATCGCTT
TTTTGTATTCCTAATACATT

Product: beta-lactamase

Products: NA

Alternate protein names: Beta-lactamase I; Penicillinase [H]

Number of amino acids: Translated: 301; Mature: 301

Protein sequence:

>301_residues
MLKIGMCVGILGLSITSLVTFTGGALQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLGVYAIDTGTNQTIAYRPNERF
AFASTYKALAAGVLLQQNSTKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGPKGY
EKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRNILTKWMKGNATGDKLIRAGVPTN
WVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKGATYDNQLIAEAAEVIVNAFR

Sequences:

>Translated_301_residues
MLKIGMCVGILGLSITSLVTFTGGALQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLGVYAIDTGTNQTIAYRPNERF
AFASTYKALAAGVLLQQNSTKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGPKGY
EKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRNILTKWMKGNATGDKLIRAGVPTN
WVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKGATYDNQLIAEAAEVIVNAFR
>Mature_301_residues
MLKIGMCVGILGLSITSLVTFTGGALQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLGVYAIDTGTNQTIAYRPNERF
AFASTYKALAAGVLLQQNSTKKLDEVITYTKEDLVDYSPVTEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGPKGY
EKALRQMGDRVTMSDRFETELNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRNILTKWMKGNATGDKLIRAGVPTN
WVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKGATYDNQLIAEAAEVIVNAFR

Specific function: Acts preferentially on penicillins [H]

COG id: COG2367

COG function: function code V; Beta-lactamase class A

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-A beta-lactamase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001466
- InterPro:   IPR000871 [H]

Pfam domain/function: PF00144 Beta-lactamase [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 32724; Mature: 32724

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS00146 BETA_LACTAMASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIGMCVGILGLSITSLVTFTGGALQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLG
CEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
VYAIDTGTNQTIAYRPNERFAFASTYKALAAGVLLQQNSTKKLDEVITYTKEDLVDYSPV
EEEEECCCCCEEEECCCCCEEHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCCCCC
TEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGPKGYEKALRQMGDRVTMSDRFETE
CHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHH
LNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRNILTKWMKGNATGDKLIRAGVPTN
HHHCCCCCCCCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHCCCCCHHHHEECCCCCC
WVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKGATYDNQLIAEAAEVIVNAF
EEEECCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHC
R
C
>Mature Secondary Structure
MLKIGMCVGILGLSITSLVTFTGGALQVEAKEKTGQVKHKNQATHKEFSQLEKKFDARLG
CEEHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
VYAIDTGTNQTIAYRPNERFAFASTYKALAAGVLLQQNSTKKLDEVITYTKEDLVDYSPV
EEEEECCCCCEEEECCCCCEEHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHCCCCCC
TEKHVDTGMTLGEIAEAAVRYSDNTAGNILFHKIGGPKGYEKALRQMGDRVTMSDRFETE
CHHHHHCCCCHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHCCCCCCCHHHHHH
LNEAIPGDIRDTSTAKAIATNLKAFTAGNALPNHKRNILTKWMKGNATGDKLIRAGVPTN
HHHCCCCCCCCCHHHHHHHHHHHHEECCCCCCCHHHHHHHHHHCCCCCHHHHEECCCCCC
WVVADKSGAGSYGTRNDIAIVWPPNRAPIIIAILSSKDEKGATYDNQLIAEAAEVIVNAF
EEEECCCCCCCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2991192 [H]