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The map label for this gene is dhbB [H]

Identifier: 49185216

GI number: 49185216

Start: 2205697

End: 2206584

Strand: Direct

Name: dhbB [H]

Synonym: BAS2207

Alternate gene names: 49185216

Gene position: 2205697-2206584 (Clockwise)

Preceding gene: 49185215

Following gene: 49185217

Centisome position: 42.18

GC content: 35.7

Gene sequence:

>888_bases
ATGGCTATCCCATCTATTTCAGTATACAAAATGCCAATTGAATCAGAATTACCAAAAAATAAAGTGAATTGGACACCAGA
TCCGAAACGTGCAGTGCTTTTAATTCATGACATGCAAGAATATTTTCTTGATGCATATAGCGATAAAGAATCACCAAAAG
TAGAACTCATTTCAAATATTAAGGTAATAAGAGAAAAATGTAAGGAACTTGGTATACCAGTTGTTTATACAGCACAGCCA
GGTGGACAAACACTAGAACAACGAGGATTATTACAAGACTTCTGGGGTGACGGTATTCCTGCTGGACCAGATAAAAAGAA
AATTGTCGATGAACTTACTCCTGATGAAGATGATATATTCTTAACAAAATGGAGATATAGTGCATTTAAAAAGACAAATC
TATTAGAAATTTTAAATGAACAAGGAAGAGATCAACTCATTATTTGCGGTATTTATGCGCATATTGGCTGCCTTTTAACA
GCTTGTGAAGCATTTATGGATGGAATTCAGCCGTTCTTTGTAGCAGATGCAGTTGCTGATTTTTCACTAGAACATCATAA
ACAAGCGTTGGAGTATGCGTCAAATAGATGTGCAGTAACGACATCAACTAACAGTTTGTTAACAGAGTTACAAGGTTTAA
AAGATGATGATGAAATCACTTTACAAAAAGTACATGAACTAGTTGCACAATTACTTCGTGAACCAGTAGAGAGTGTTGGG
ACTGATGAAGATTTATTAAATAGAGGACTTGATTCGGTCAGAATTATGAGTTTAGTAGAGAAGTGGCGTCGCGAAGGAAA
GGAGATTACTTTTGCGGATTTAGCAGAGAACCCAACGGTTGTTGATTGGTATCGCTTATTATCTCCGCAAACAGAACATG
TACTTTAA

Upstream 100 bases:

>100_bases
GTTGGAAAGGTAAGCAAAAAAGAATTACGTAAAGTCATTGCGGAAAAACTTGTTACGGTAAAAAGATAAAAAAATATAAA
ACTTGGAAGGAAGTGATTAG

Downstream 100 bases:

>100_bases
TATAGACTACATAATAAAGGGGTAGTAAAGAATGCCTAATAGTCAAAAGGTTCGTCATTCGTTATCATCTGCGCAGTCTG
GTATGTGGTTTGCGCAACAA

Product: isochorismatase

Products: NA

Alternate protein names: 2,3 dihydro-2,3 dihydroxybenzoate synthase; Superoxide-inducible protein 1; SOI1 [H]

Number of amino acids: Translated: 295; Mature: 294

Protein sequence:

>295_residues
MAIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNIKVIREKCKELGIPVVYTAQP
GGQTLEQRGLLQDFWGDGIPAGPDKKKIVDELTPDEDDIFLTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLT
ACEAFMDGIQPFFVADAVADFSLEHHKQALEYASNRCAVTTSTNSLLTELQGLKDDDEITLQKVHELVAQLLREPVESVG
TDEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSPQTEHVL

Sequences:

>Translated_295_residues
MAIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNIKVIREKCKELGIPVVYTAQP
GGQTLEQRGLLQDFWGDGIPAGPDKKKIVDELTPDEDDIFLTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLT
ACEAFMDGIQPFFVADAVADFSLEHHKQALEYASNRCAVTTSTNSLLTELQGLKDDDEITLQKVHELVAQLLREPVESVG
TDEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSPQTEHVL
>Mature_294_residues
AIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNIKVIREKCKELGIPVVYTAQPG
GQTLEQRGLLQDFWGDGIPAGPDKKKIVDELTPDEDDIFLTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLTA
CEAFMDGIQPFFVADAVADFSLEHHKQALEYASNRCAVTTSTNSLLTELQGLKDDDEITLQKVHELVAQLLREPVESVGT
DEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSPQTEHVL

Specific function: Required For Production Of 2,3-Dhb. Also Serves As An Aryl Carrier Protein And Plays A Role In Enterobactin Assembly. [C]

COG id: COG1535

COG function: function code Q; Isochorismate hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 acyl carrier domain [H]

Homologues:

Organism=Escherichia coli, GI1786811, Length=290, Percent_Identity=45.8620689655172, Blast_Score=267, Evalue=8e-73,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009081
- InterPro:   IPR016291
- InterPro:   IPR000868
- InterPro:   IPR006163 [H]

Pfam domain/function: PF00857 Isochorismatase; PF00550 PP-binding [H]

EC number: =3.3.2.1 [H]

Molecular weight: Translated: 33431; Mature: 33299

Theoretical pI: Translated: 4.55; Mature: 4.55

Prosite motif: PS50075 ACP_DOMAIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNI
CCCCCCEEEECCCHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCHHHHHHHH
KVIREKCKELGIPVVYTAQPGGQTLEQRGLLQDFWGDGIPAGPDKKKIVDELTPDEDDIF
HHHHHHHHHCCCCEEEECCCCCHHHHHCCCHHHHCCCCCCCCCCHHHHHHHCCCCCCCEE
LTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLTACEAFMDGIQPFFVADAVAD
EEEHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FSLEHHKQALEYASNRCAVTTSTNSLLTELQGLKDDDEITLQKVHELVAQLLREPVESVG
HHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
TDEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSPQTEHVL
CCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHCCCHHCCC
>Mature Secondary Structure 
AIPSISVYKMPIESELPKNKVNWTPDPKRAVLLIHDMQEYFLDAYSDKESPKVELISNI
CCCCCEEEECCCHHCCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHCCCCCCHHHHHHHH
KVIREKCKELGIPVVYTAQPGGQTLEQRGLLQDFWGDGIPAGPDKKKIVDELTPDEDDIF
HHHHHHHHHCCCCEEEECCCCCHHHHHCCCHHHHCCCCCCCCCCHHHHHHHCCCCCCCEE
LTKWRYSAFKKTNLLEILNEQGRDQLIICGIYAHIGCLLTACEAFMDGIQPFFVADAVAD
EEEHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
FSLEHHKQALEYASNRCAVTTSTNSLLTELQGLKDDDEITLQKVHELVAQLLREPVESVG
HHHHHHHHHHHHHCCCEEEEECHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
TDEDLLNRGLDSVRIMSLVEKWRREGKEITFADLAENPTVVDWYRLLSPQTEHVL
CCHHHHHCCHHHHHHHHHHHHHHHCCCCEEEHHHCCCCCHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8550523; 9384377; 9298659 [H]